JP2007530971A5 - - Google Patents
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- Publication number
- JP2007530971A5 JP2007530971A5 JP2007506111A JP2007506111A JP2007530971A5 JP 2007530971 A5 JP2007530971 A5 JP 2007530971A5 JP 2007506111 A JP2007506111 A JP 2007506111A JP 2007506111 A JP2007506111 A JP 2007506111A JP 2007530971 A5 JP2007530971 A5 JP 2007530971A5
- Authority
- JP
- Japan
- Prior art keywords
- exchange chromatography
- liquid
- ion exchange
- matrix
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0400886-8 | 2004-04-02 | ||
| SE0400886A SE0400886D0 (sv) | 2004-04-02 | 2004-04-02 | Process of purification |
| PCT/SE2005/000467 WO2005094960A1 (en) | 2004-04-02 | 2005-03-31 | A method for chromatographic purification |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007530971A JP2007530971A (ja) | 2007-11-01 |
| JP2007530971A5 true JP2007530971A5 (https=) | 2008-05-15 |
| JP4831697B2 JP4831697B2 (ja) | 2011-12-07 |
Family
ID=32173667
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007506111A Expired - Lifetime JP4831697B2 (ja) | 2004-04-02 | 2005-03-31 | 精製方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20070213513A1 (https=) |
| EP (1) | EP1729867B1 (https=) |
| JP (1) | JP4831697B2 (https=) |
| AT (1) | ATE485880T1 (https=) |
| AU (1) | AU2005228834A1 (https=) |
| CA (1) | CA2560012A1 (https=) |
| DE (1) | DE602005024373D1 (https=) |
| SE (1) | SE0400886D0 (https=) |
| WO (1) | WO2005094960A1 (https=) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI456062B (zh) | 2006-09-13 | 2014-10-11 | Abbvie Inc | 細胞培養改良 |
| US8911964B2 (en) | 2006-09-13 | 2014-12-16 | Abbvie Inc. | Fed-batch method of making human anti-TNF-alpha antibody |
| WO2008156410A1 (en) * | 2007-06-19 | 2008-12-24 | Ge Healthcare Bio-Sciences Ab | Polymer two phase system and use thereof |
| WO2009090056A2 (en) | 2008-01-18 | 2009-07-23 | F. Hoffmann-La Roche Ag | Purification of not-glycosylated polypeptides |
| WO2009099375A1 (en) * | 2008-02-05 | 2009-08-13 | Ge Healthcare Bio-Sciences Ab | Method for production of separation media |
| FR2930780B1 (fr) | 2008-04-30 | 2010-08-20 | Moet & Chandon | Procede de degorgement de vins mousseux |
| CN102119168A (zh) * | 2008-06-03 | 2011-07-06 | 帕特里有限公司 | 抗体纯化工艺 |
| MX2011004201A (es) | 2008-10-20 | 2011-05-24 | Abbott Lab | Desactivacion viral durante purificacion de anticuerpos. |
| AU2009347206C1 (en) | 2008-10-20 | 2016-12-08 | Abbvie Inc. | Isolation and purification of antibodies using Protein A affinity chromatography |
| EP3318571B1 (en) | 2011-03-16 | 2021-02-17 | F. Hoffmann-La Roche AG | Ion exchange chromatography with improved selectivity for the separation of polypeptide monomers, aggregates and fragments by modulation of the mobile phase |
| KR102058254B1 (ko) | 2011-03-29 | 2019-12-20 | 글락소스미스클라인 엘엘씨 | 단백질 정제용 완충제 시스템 |
| SG195306A1 (en) * | 2011-06-08 | 2013-12-30 | Agency Science Tech & Res | Purification of biological products by constrained cohydration chromatography |
| EP2682168A1 (en) | 2012-07-02 | 2014-01-08 | Millipore Corporation | Purification of biological molecules |
| US10023608B1 (en) | 2013-03-13 | 2018-07-17 | Amgen Inc. | Protein purification methods to remove impurities |
| JPWO2015041218A1 (ja) * | 2013-09-17 | 2017-03-02 | 株式会社カネカ | 新規抗体精製方法及びそれから得られる抗体（ＮｏｖｅｌＡｎｔｉｂｏｄｙＰｕｒｉｆｉｃａｔｉｏｎＭｅｔｈｏｄａｎｄＡｎｔｉｂｏｄｙｏｂｔａｉｎｅｄｔｈｅｒｅｆｒｏｍ）、並びに陽イオン交換基を用いた新規抗体精製法及びそれから得られる抗体（ＮｏｖｅｌＡｎｔｉｂｏｄｙＰｕｒｉｆｉｃａｔｉｏｎｍｅｔｈｏｄｕｓｉｎｇＣａｔｉｏｎＥｘｃｈａｎｇｅｒａｎｄＡｎｔｉｂｏｄｙｏｂｔａｉｎｅｄｔｈｅｒｅｆｒｏｍ） |
| TW201628649A (zh) | 2014-10-09 | 2016-08-16 | 再生元醫藥公司 | 減少醫藥調配物中微可見顆粒之方法 |
| KR102369014B1 (ko) | 2016-08-16 | 2022-03-02 | 리제너론 파아마슈티컬스, 인크. | 혼합물로부터 개별 항체들을 정량하는 방법 |
| EA201990986A1 (ru) | 2016-10-25 | 2019-09-30 | Ридженерон Фармасьютикалз, Инк. | Способы и системы анализа хроматографических данных |
| WO2019060062A1 (en) | 2017-09-19 | 2019-03-28 | Regeneron Pharmaceuticals Inc. | METHODS OF REDUCING PARTICLE FORMATION AND COMPOSITIONS FORMED THEREFROM |
| CN108152104B (zh) * | 2017-12-25 | 2020-08-11 | 上海微谱化工技术服务有限公司 | 超支化水性聚氨酯中二氧化硅填料的分离及定量方法 |
| CN111902720B (zh) | 2018-03-21 | 2025-02-07 | 沃特世科技公司 | 基于非抗体高亲和力的样品制备、吸附剂、装置和方法 |
| WO2019237100A1 (en) * | 2018-06-08 | 2019-12-12 | Board Of Regents, The University Of Texas System | Systems and methods for separation of olefins from mixtures that contain reducing agents |
| TWI853823B (zh) | 2018-07-02 | 2024-09-01 | 美商里珍納龍藥品有限公司 | 自混合物製備多肽之系統及方法 |
| EA202192422A1 (ru) | 2019-03-05 | 2021-12-09 | Ридженерон Фармасьютикалз, Инк. | Человеческий сывороточный альбумин в составах |
| JP2022550837A (ja) * | 2019-10-04 | 2022-12-05 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | プロテインａアフィニティークロマトグラフィーにおけるモノクローナル抗体の溶離 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3869436A (en) * | 1971-06-01 | 1975-03-04 | Statens Bakteriologiska Lab | Method for fractionating plasma proteins using peg and ion-exchangers |
| EP0119767B1 (en) * | 1983-03-11 | 1990-11-22 | FUJIREBIO KABUSHIKI KAISHA also trading as FUJIREBIO INC. | Method of measuring ligands |
| US4683294A (en) * | 1985-04-03 | 1987-07-28 | Smith Kline Rit, S.A. | Process for the extraction and purification of proteins from culture media producing them |
| ES2052602T3 (es) * | 1986-10-03 | 1994-07-16 | Ciba Geigy Ag | Nuevos peptidos afines a las linfocinas. |
| US5151358A (en) * | 1989-06-13 | 1992-09-29 | Genencor International, Inc. | Processes for the recovery of naturally produced chymosin |
| DE4321904B4 (de) * | 1993-07-01 | 2013-05-16 | Qiagen Gmbh | Verfahren zur chromatographischen Reinigung und Trennung von Nucleinsäuregemischen |
| US5443953A (en) * | 1993-12-08 | 1995-08-22 | Immunomedics, Inc. | Preparation and use of immunoconjugates |
| US5561064A (en) * | 1994-02-01 | 1996-10-01 | Vical Incorporated | Production of pharmaceutical-grade plasmid DNA |
| US5429746A (en) * | 1994-02-22 | 1995-07-04 | Smith Kline Beecham Corporation | Antibody purification |
| SE9503925D0 (sv) * | 1995-11-07 | 1995-11-07 | Pharmacia Biotech Ab | Separationsmedium för IgG |
| CA2268085A1 (en) * | 1996-10-22 | 1998-04-30 | Go Wakabayashi | Sepsis remedy comprising anti-il-8 antibody as active ingredient |
| AUPR110100A0 (en) * | 2000-10-30 | 2000-11-23 | Life Therapeutics Limited | Improved separation of macromolecules |
| US7514078B2 (en) * | 2001-06-01 | 2009-04-07 | Cornell Research Foundation, Inc. | Methods of treating prostate cancer with anti-prostate specific membrane antigen antibodies |
| US7998705B2 (en) * | 2002-08-06 | 2011-08-16 | FUJIFILM Diosynth Biotechnologies U.S.A., Inc | Increased dynamic binding capacity in ion exchange chromatography by addition of polyethylene glycol |
| US20060275766A1 (en) * | 2003-01-07 | 2006-12-07 | Haurum John S | Method for manufacturing recombinant polyclonal proteins |
-
2004
- 2004-04-02 SE SE0400886A patent/SE0400886D0/xx unknown
-
2005
- 2005-03-31 WO PCT/SE2005/000467 patent/WO2005094960A1/en not_active Ceased
- 2005-03-31 US US10/594,187 patent/US20070213513A1/en not_active Abandoned
- 2005-03-31 JP JP2007506111A patent/JP4831697B2/ja not_active Expired - Lifetime
- 2005-03-31 DE DE602005024373T patent/DE602005024373D1/de not_active Expired - Lifetime
- 2005-03-31 EP EP05722292A patent/EP1729867B1/en not_active Expired - Lifetime
- 2005-03-31 AT AT05722292T patent/ATE485880T1/de not_active IP Right Cessation
- 2005-03-31 AU AU2005228834A patent/AU2005228834A1/en not_active Abandoned
- 2005-03-31 CA CA002560012A patent/CA2560012A1/en not_active Abandoned
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