JP2007530971A5 - - Google Patents

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Publication number
JP2007530971A5
JP2007530971A5 JP2007506111A JP2007506111A JP2007530971A5 JP 2007530971 A5 JP2007530971 A5 JP 2007530971A5 JP 2007506111 A JP2007506111 A JP 2007506111A JP 2007506111 A JP2007506111 A JP 2007506111A JP 2007530971 A5 JP2007530971 A5 JP 2007530971A5
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JP
Japan
Prior art keywords
exchange chromatography
liquid
ion exchange
matrix
antibody
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Application number
JP2007506111A
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English (en)
Japanese (ja)
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JP4831697B2 (ja
JP2007530971A (ja
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Publication date
Priority claimed from SE0400886A external-priority patent/SE0400886D0/xx
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Publication of JP2007530971A publication Critical patent/JP2007530971A/ja
Publication of JP2007530971A5 publication Critical patent/JP2007530971A5/ja
Application granted granted Critical
Publication of JP4831697B2 publication Critical patent/JP4831697B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP2007506111A 2004-04-02 2005-03-31 精製方法 Expired - Lifetime JP4831697B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0400886A SE0400886D0 (sv) 2004-04-02 2004-04-02 Process of purification
SE0400886-8 2004-04-02
PCT/SE2005/000467 WO2005094960A1 (en) 2004-04-02 2005-03-31 A method for chromatographic purification

Publications (3)

Publication Number Publication Date
JP2007530971A JP2007530971A (ja) 2007-11-01
JP2007530971A5 true JP2007530971A5 (https=) 2008-05-15
JP4831697B2 JP4831697B2 (ja) 2011-12-07

Family

ID=32173667

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007506111A Expired - Lifetime JP4831697B2 (ja) 2004-04-02 2005-03-31 精製方法

Country Status (9)

Country Link
US (1) US20070213513A1 (https=)
EP (1) EP1729867B1 (https=)
JP (1) JP4831697B2 (https=)
AT (1) ATE485880T1 (https=)
AU (1) AU2005228834A1 (https=)
CA (1) CA2560012A1 (https=)
DE (1) DE602005024373D1 (https=)
SE (1) SE0400886D0 (https=)
WO (1) WO2005094960A1 (https=)

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KR20100103595A (ko) * 2008-01-18 2010-09-27 에프. 호프만-라 로슈 아게 비-글라이코실화된 단백질의 정제
CN101939094B (zh) * 2008-02-05 2013-11-20 通用电气健康护理生物科学股份公司 分离介质的制备方法
FR2930780B1 (fr) * 2008-04-30 2010-08-20 Moet & Chandon Procede de degorgement de vins mousseux
CN102119168A (zh) * 2008-06-03 2011-07-06 帕特里有限公司 抗体纯化工艺
NZ592095A (en) 2008-10-20 2013-01-25 Abbott Lab Isolation and purification of il-12 and tnf-alpha antibodies using protein a affinity chromatography
BRPI0920572A8 (pt) 2008-10-20 2015-10-27 Abbott Lab Inativação viral durante a purificação dos anticorpos
EP2686334B2 (en) 2011-03-16 2020-07-01 F.Hoffmann-La Roche Ag Ion exchange chromatography with improved selectivity for the separation of polypeptide monomers, aggregates and fragments by modulation of the mobile phase
CN107915769A (zh) 2011-03-29 2018-04-17 葛兰素史密斯克莱有限责任公司 用于蛋白纯化的缓冲液体系
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EP2682168A1 (en) 2012-07-02 2014-01-08 Millipore Corporation Purification of biological molecules
US10023608B1 (en) 2013-03-13 2018-07-17 Amgen Inc. Protein purification methods to remove impurities
JPWO2015041218A1 (ja) * 2013-09-17 2017-03-02 株式会社カネカ 新規抗体精製方法及びそれから得られる抗体（ＮｏｖｅｌＡｎｔｉｂｏｄｙＰｕｒｉｆｉｃａｔｉｏｎＭｅｔｈｏｄａｎｄＡｎｔｉｂｏｄｙｏｂｔａｉｎｅｄｔｈｅｒｅｆｒｏｍ）、並びに陽イオン交換基を用いた新規抗体精製法及びそれから得られる抗体（ＮｏｖｅｌＡｎｔｉｂｏｄｙＰｕｒｉｆｉｃａｔｉｏｎｍｅｔｈｏｄｕｓｉｎｇＣａｔｉｏｎＥｘｃｈａｎｇｅｒａｎｄＡｎｔｉｂｏｄｙｏｂｔａｉｎｅｄｔｈｅｒｅｆｒｏｍ）
AR102198A1 (es) 2014-10-09 2017-02-08 Regeneron Pharma Proceso para reducir partículas subvisibles en una formulación farmacéutica
US11020686B2 (en) 2016-08-16 2021-06-01 Regeneron Pharmaceuticals, Inc. Methods for quantitating individual antibodies from a mixture
JP7102401B2 (ja) 2016-10-25 2022-07-19 リジェネロン・ファーマシューティカルズ・インコーポレイテッド クロマトグラフィーデータ解析のための方法およびシステム
CA3073935A1 (en) 2017-09-19 2019-03-28 Regeneron Pharmaceuticals, Inc. Methods of reducing particle formation and compositions formed thereby
CN108152104B (zh) * 2017-12-25 2020-08-11 上海微谱化工技术服务有限公司 超支化水性聚氨酯中二氧化硅填料的分离及定量方法
WO2019183334A1 (en) 2018-03-21 2019-09-26 Waters Technologies Corporation Non-antibody high-affinity-based sample preparation, sorbents, devices and methods
WO2019237100A1 (en) * 2018-06-08 2019-12-12 Board Of Regents, The University Of Texas System Systems and methods for separation of olefins from mixtures that contain reducing agents
TWI853823B (zh) 2018-07-02 2024-09-01 美商里珍納龍藥品有限公司 自混合物製備多肽之系統及方法
EA202192422A1 (ru) 2019-03-05 2021-12-09 Ридженерон Фармасьютикалз, Инк. Человеческий сывороточный альбумин в составах
JP2022550837A (ja) * 2019-10-04 2022-12-05 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング プロテインａアフィニティークロマトグラフィーにおけるモノクローナル抗体の溶離

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