JP2007530737A5 - - Google Patents
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- JP2007530737A5 JP2007530737A5 JP2007505079A JP2007505079A JP2007530737A5 JP 2007530737 A5 JP2007530737 A5 JP 2007530737A5 JP 2007505079 A JP2007505079 A JP 2007505079A JP 2007505079 A JP2007505079 A JP 2007505079A JP 2007530737 A5 JP2007530737 A5 JP 2007530737A5
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- 229920000642 polymer Polymers 0.000 claims 23
- 239000000203 mixture Substances 0.000 claims 22
- 150000001412 amines Chemical group 0.000 claims 17
- 239000002245 particle Substances 0.000 claims 13
- 239000002253 acid Substances 0.000 claims 9
- 239000003431 cross linking reagent Substances 0.000 claims 7
- 125000003118 aryl group Chemical group 0.000 claims 4
- 238000004132 cross linking Methods 0.000 claims 4
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 claims 4
- OFOBLEOULBTSOW-UHFFFAOYSA-N Propanedioic acid Natural products OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 claims 3
- 229920001577 copolymer Polymers 0.000 claims 3
- 239000011976 maleic acid Substances 0.000 claims 3
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 claims 2
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims 2
- 229920002126 Acrylic acid copolymer Polymers 0.000 claims 2
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 claims 2
- 229920002125 Sokalan® Polymers 0.000 claims 2
- PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Chemical compound C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 claims 2
- 125000002723 alicyclic group Chemical group 0.000 claims 2
- 150000008064 anhydrides Chemical group 0.000 claims 2
- 150000002148 esters Chemical class 0.000 claims 2
- 125000000524 functional group Chemical group 0.000 claims 2
- 125000000623 heterocyclic group Chemical group 0.000 claims 2
- 125000000547 substituted alkyl group Chemical group 0.000 claims 2
- YHRUOJUYPBUZOS-UHFFFAOYSA-N 1,3-dichloropropane Chemical group ClCCCCl YHRUOJUYPBUZOS-UHFFFAOYSA-N 0.000 claims 1
- JAHNSTQSQJOJLO-UHFFFAOYSA-N 2-(3-fluorophenyl)-1h-imidazole Chemical compound FC1=CC=CC(C=2NC=CN=2)=C1 JAHNSTQSQJOJLO-UHFFFAOYSA-N 0.000 claims 1
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims 1
- 229920000623 Cellulose acetate phthalate Polymers 0.000 claims 1
- BRLQWZUYTZBJKN-UHFFFAOYSA-N Epichlorohydrin Chemical compound ClCC1CO1 BRLQWZUYTZBJKN-UHFFFAOYSA-N 0.000 claims 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical group OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 claims 1
- 229920002845 Poly(methacrylic acid) Polymers 0.000 claims 1
- 239000013543 active substance Substances 0.000 claims 1
- 229920000615 alginic acid Polymers 0.000 claims 1
- 239000000783 alginic acid Substances 0.000 claims 1
- 235000010443 alginic acid Nutrition 0.000 claims 1
- 229960001126 alginic acid Drugs 0.000 claims 1
- -1 alginic acid ester Chemical class 0.000 claims 1
- 239000011324 bead Substances 0.000 claims 1
- 125000005620 boronic acid group Chemical group 0.000 claims 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 claims 1
- 239000001768 carboxy methyl cellulose Substances 0.000 claims 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims 1
- 125000002843 carboxylic acid group Chemical group 0.000 claims 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 claims 1
- 229940105329 carboxymethylcellulose Drugs 0.000 claims 1
- 229920001525 carrageenan Polymers 0.000 claims 1
- 239000000679 carrageenan Substances 0.000 claims 1
- 235000010418 carrageenan Nutrition 0.000 claims 1
- 229940113118 carrageenan Drugs 0.000 claims 1
- 229940081734 cellulose acetate phthalate Drugs 0.000 claims 1
- AOGYCOYQMAVAFD-UHFFFAOYSA-N chlorocarbonic acid Chemical group OC(Cl)=O AOGYCOYQMAVAFD-UHFFFAOYSA-N 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 229920006037 cross link polymer Polymers 0.000 claims 1
- DMSZORWOGDLWGN-UHFFFAOYSA-N ctk1a3526 Chemical group NP(N)(N)=O DMSZORWOGDLWGN-UHFFFAOYSA-N 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 125000003700 epoxy group Chemical group 0.000 claims 1
- 125000004185 ester group Chemical group 0.000 claims 1
- 239000001530 fumaric acid Substances 0.000 claims 1
- 150000004820 halides Chemical group 0.000 claims 1
- 125000005843 halogen group Chemical group 0.000 claims 1
- 229920003132 hydroxypropyl methylcellulose phthalate Polymers 0.000 claims 1
- 229940031704 hydroxypropyl methylcellulose phthalate Drugs 0.000 claims 1
- 201000005991 hyperphosphatemia Diseases 0.000 claims 1
- IQPQWNKOIGAROB-UHFFFAOYSA-N isocyanate group Chemical group [N-]=C=O IQPQWNKOIGAROB-UHFFFAOYSA-N 0.000 claims 1
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- LVHBHZANLOWSRM-UHFFFAOYSA-N methylenebutanedioic acid Natural products OC(=O)CC(=C)C(O)=O LVHBHZANLOWSRM-UHFFFAOYSA-N 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 229940124531 pharmaceutical excipient Drugs 0.000 claims 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N phenol group Chemical group C1(=CC=CC=C1)O ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 claims 1
- ABLZXFCXXLZCGV-UHFFFAOYSA-N phosphonic acid group Chemical group P(O)(O)=O ABLZXFCXXLZCGV-UHFFFAOYSA-N 0.000 claims 1
- 229920001467 poly(styrenesulfonates) Polymers 0.000 claims 1
- IIACRCGMVDHOTQ-UHFFFAOYSA-N sulfamic acid group Chemical group S(N)(O)(=O)=O IIACRCGMVDHOTQ-UHFFFAOYSA-N 0.000 claims 1
- 125000000542 sulfonic acid group Chemical group 0.000 claims 1
- 230000008961 swelling Effects 0.000 claims 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 claims 1
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/806,495 US7335795B2 (en) | 2004-03-22 | 2004-03-22 | Crosslinked amine polymers |
| US10/965,044 US7459502B2 (en) | 2003-11-03 | 2004-10-13 | Pharmaceutical compositions comprising crosslinked polyamine polymers |
| US10/980,991 US7608674B2 (en) | 2003-11-03 | 2004-11-03 | Pharmaceutical compositions comprising cross-linked small molecule amine polymers |
| PCT/US2005/009394 WO2005092039A2 (en) | 2004-03-22 | 2005-03-22 | Crosslinked amine polymers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007530737A JP2007530737A (ja) | 2007-11-01 |
| JP2007530737A5 true JP2007530737A5 (https=) | 2008-05-08 |
Family
ID=35056753
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007505079A Withdrawn JP2007530737A (ja) | 2004-03-22 | 2005-03-22 | 架橋アミンポリマー |
Country Status (4)
| Country | Link |
|---|---|
| US (3) | US7608674B2 (https=) |
| EP (1) | EP1742613A4 (https=) |
| JP (1) | JP2007530737A (https=) |
| WO (1) | WO2005092039A2 (https=) |
Families Citing this family (59)
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| US6733780B1 (en) | 1999-10-19 | 2004-05-11 | Genzyme Corporation | Direct compression polymer tablet core |
| US7381428B2 (en) | 2003-08-26 | 2008-06-03 | Shire International Licensing B.V. | Stabilized lanthanum carbonate compositions |
| MXPA06002257A (es) * | 2003-08-26 | 2006-05-17 | Shire Holdings Ag | Farmaceutica que comprende compuestos de lantano. |
| US7608674B2 (en) * | 2003-11-03 | 2009-10-27 | Ilypsa, Inc. | Pharmaceutical compositions comprising cross-linked small molecule amine polymers |
| US7385012B2 (en) | 2003-11-03 | 2008-06-10 | Ilypsa, Inc. | Polyamine polymers |
| US7335795B2 (en) * | 2004-03-22 | 2008-02-26 | Ilypsa, Inc. | Crosslinked amine polymers |
| US7459502B2 (en) * | 2003-11-03 | 2008-12-02 | Ilypsa, Inc. | Pharmaceutical compositions comprising crosslinked polyamine polymers |
| US7767768B2 (en) * | 2003-11-03 | 2010-08-03 | Ilypsa, Inc. | Crosslinked amine polymers |
| US7449605B2 (en) * | 2003-11-03 | 2008-11-11 | Ilypsa, Inc. | Crosslinked amine polymers |
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| US7985418B2 (en) | 2004-11-01 | 2011-07-26 | Genzyme Corporation | Aliphatic amine polymer salts for tableting |
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| US8114393B2 (en) * | 2005-09-14 | 2012-02-14 | Wisconsin Alumni Research Foundation | Methods and compositions for phosphate binding |
| US8158117B2 (en) | 2005-09-14 | 2012-04-17 | Wisconsin Alumni Research Foundation | Methods and compositions for phosphate binding |
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| TR201910825T4 (tr) * | 2006-12-22 | 2019-08-21 | Ironwood Pharmaceuticals Inc | Yemek borusu rahatsizliklarini tedavi̇ etmek i̇çi̇n yöntemler ve bi̇leşi̇mler |
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-
2004
- 2004-11-03 US US10/980,991 patent/US7608674B2/en not_active Expired - Fee Related
-
2005
- 2005-03-22 JP JP2007505079A patent/JP2007530737A/ja not_active Withdrawn
- 2005-03-22 EP EP05730071A patent/EP1742613A4/en not_active Withdrawn
- 2005-03-22 WO PCT/US2005/009394 patent/WO2005092039A2/en not_active Ceased
-
2006
- 2006-08-17 US US11/465,444 patent/US7589238B2/en not_active Expired - Fee Related
-
2009
- 2009-05-22 US US12/471,220 patent/US7718746B2/en not_active Expired - Fee Related
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