JP2007528372A5 - - Google Patents
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- JP2007528372A5 JP2007528372A5 JP2006553216A JP2006553216A JP2007528372A5 JP 2007528372 A5 JP2007528372 A5 JP 2007528372A5 JP 2006553216 A JP2006553216 A JP 2006553216A JP 2006553216 A JP2006553216 A JP 2006553216A JP 2007528372 A5 JP2007528372 A5 JP 2007528372A5
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- molecule
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- 0 CC(C)(C)OC(CN(CCN(CC(*)=*)CC(OC(C)(C)C)=O)CCN(CC(OC(C)(C)C)=O)CC(OC(C)(C)C)=O)=O Chemical compound CC(C)(C)OC(CN(CCN(CC(*)=*)CC(OC(C)(C)C)=O)CCN(CC(OC(C)(C)C)=O)CC(OC(C)(C)C)=O)=O 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/776,470 US7405320B2 (en) | 1998-06-22 | 2004-02-11 | Therapeutic and diagnostic conjugates for use with multispecific antibodies |
| US10/776,470 | 2004-02-11 | ||
| PCT/US2005/004177 WO2005077071A2 (en) | 2004-02-11 | 2005-02-11 | Therapeutic and diagnostic conjugates for use with multispecific antibodies |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007528372A JP2007528372A (ja) | 2007-10-11 |
| JP2007528372A5 true JP2007528372A5 (https=) | 2008-03-27 |
| JP5084267B2 JP5084267B2 (ja) | 2012-11-28 |
Family
ID=34860853
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006553216A Expired - Fee Related JP5084267B2 (ja) | 2004-02-11 | 2005-02-11 | 多特異性抗体との使用のための治療および診断用コンジュゲート |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US7405320B2 (https=) |
| EP (1) | EP1720575B1 (https=) |
| JP (1) | JP5084267B2 (https=) |
| AU (2) | AU2005211754B2 (https=) |
| CA (2) | CA2819492C (https=) |
| WO (1) | WO2005077071A2 (https=) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7591994B2 (en) | 2002-12-13 | 2009-09-22 | Immunomedics, Inc. | Camptothecin-binding moiety conjugates |
| US8491896B2 (en) * | 2002-06-14 | 2013-07-23 | Immunomedics, Inc. | Anti-pancreatic cancer antibodies |
| US8877901B2 (en) | 2002-12-13 | 2014-11-04 | Immunomedics, Inc. | Camptothecin-binding moiety conjugates |
| US8435529B2 (en) | 2002-06-14 | 2013-05-07 | Immunomedics, Inc. | Combining radioimmunotherapy and antibody-drug conjugates for improved cancer therapy |
| ES2524767T3 (es) * | 2002-06-14 | 2014-12-12 | Immunomedics, Inc. | Anticuerpo monoclonal humanizado HPAM4 |
| US9599619B2 (en) | 2002-06-14 | 2017-03-21 | Immunomedics, Inc. | Anti-pancreatic cancer antibodies |
| RU2005100777A (ru) * | 2002-06-14 | 2005-08-27 | Иммуномедикс, Инк. (Us) | Моноклональное антитело рам4 и его применение для диагностики и лечения рака поджелудочной железы |
| US8821868B2 (en) | 2002-06-14 | 2014-09-02 | Immunomedics, Inc. | Anti-pancreatic cancer antibodies |
| US7601351B1 (en) | 2002-06-26 | 2009-10-13 | Human Genome Sciences, Inc. | Antibodies against protective antigen |
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| US8652484B2 (en) * | 2004-02-13 | 2014-02-18 | Immunomedics, Inc. | Delivery system for cytotoxic drugs by bispecific antibody pretargeting |
| ES2665422T3 (es) | 2005-03-03 | 2018-04-25 | Immunomedics Inc. | Anticuerpos L243 humanizados |
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| US20110159523A1 (en) * | 2007-06-27 | 2011-06-30 | Cedars-Sinai Medical Center | N-terminal specific chemical labeling for proteomics applications |
| PL2039679T3 (pl) * | 2007-09-20 | 2015-10-30 | Przed Produkcyjno Consultingowe Adob Sp Z O O Sp K | Sposób wytwarzania kwasu N,N'-di(2-hydroksybenzylo)etylenodiamino-N,N'-dioctowego i jego pochodnych |
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| EP2147683A1 (en) * | 2008-07-25 | 2010-01-27 | DKFZ Deutsches Krebsforschungszentrum | Construct and method for the internalization of cargo molecules into a cell |
| AU2011207189B2 (en) | 2008-08-08 | 2014-01-16 | Immunomedics, Inc. | Detection of early-stage pancreatic adenocarcinoma |
| ES3000111T3 (en) | 2009-02-13 | 2025-02-27 | Immunomedics Inc | Intermediates for preparing conjugates with an intracellularly-cleavable linkage |
| US20160095939A1 (en) | 2014-10-07 | 2016-04-07 | Immunomedics, Inc. | Neoadjuvant use of antibody-drug conjugates |
| EP2478110B1 (en) | 2009-09-16 | 2016-01-06 | Immunomedics, Inc. | Class i anti-cea antibodies and uses thereof |
| ES2978177T3 (es) | 2009-12-02 | 2024-09-06 | Immunomedics Inc | Combinación de radio inmunoterapia y conjugados anticuerpo-fármaco para mejorar la terapia contra el cáncer |
| AU2010326004B2 (en) * | 2009-12-04 | 2016-04-21 | Immunomedics, Inc. | Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules |
| WO2011139379A2 (en) | 2010-05-06 | 2011-11-10 | Duke University | A method of treating patients undergoing protein replacement therapy, gene replacement therapy, or other therapeutic modalities |
| EP2675485A4 (en) | 2011-02-15 | 2014-10-15 | Immunomedics Inc | ANTI-MUCIN ANTIBODY FOR THE EARLY RECOGNITION AND TREATMENT OF PANCREATIC CANCER |
| US9623117B2 (en) * | 2011-04-04 | 2017-04-18 | Wisconsin Alumni Research Foundation | Method for selective targeting and entry of bacterial toxins to cells |
| EP2699596A4 (en) | 2011-04-22 | 2015-01-14 | Emergent Product Dev Seattle | PROSTATE-SPECIFIC MEMBRANE-BINDING PROTEINS AND COMPOSITIONS AND METHOD THEREFOR |
| US9757458B2 (en) | 2011-12-05 | 2017-09-12 | Immunomedics, Inc. | Crosslinking of CD22 by epratuzumab triggers BCR signaling and caspase-dependent apoptosis in hematopoietic cancer cells |
| US9382329B2 (en) | 2012-08-14 | 2016-07-05 | Ibc Pharmaceuticals, Inc. | Disease therapy by inducing immune response to Trop-2 expressing cells |
| CN104379169A (zh) | 2012-08-14 | 2015-02-25 | Ibc药品公司 | 用于治疗疾病的t-细胞重定向双特异性抗体 |
| CN107753954A (zh) | 2012-12-13 | 2018-03-06 | 免疫医疗公司 | 功效改进且毒性降低的抗体与sn‑38的免疫缀合物的剂量 |
| WO2017004144A1 (en) | 2015-07-01 | 2017-01-05 | Immunomedics, Inc. | Antibody-sn-38 immunoconjugates with a cl2a linker |
| US9452228B2 (en) | 2013-04-01 | 2016-09-27 | Immunomedics, Inc. | Antibodies reactive with an epitope located in the N-terminal region of MUC5AC comprising cysteine-rich subdomain 2 (Cys2) |
| GB201314718D0 (en) * | 2013-08-16 | 2013-10-02 | Algeta As | Quantification method |
| JP6447933B2 (ja) | 2014-02-21 | 2019-01-09 | アイビーシー ファーマスーティカルズ，インコーポレイテッド | Ｔｒｏｐ−２発現細胞に対する免疫応答を誘発することによる疾患治療 |
| WO2016161102A1 (en) * | 2015-04-02 | 2016-10-06 | The Research Foundation For The State University Of New York | A supramolecular chitosan complex drug delivery platform |
| AU2016252771B2 (en) | 2015-04-22 | 2021-12-16 | Immunomedics, Inc. | Isolation, detection, diagnosis and/or characterization of circulating Trop-2-positive cancer cells |
| JP6980980B2 (ja) | 2015-06-25 | 2021-12-15 | イミューノメディクス、インコーポレイテッドImmunomedics, Inc. | 抗ｈｌａ‐ｄｒまたは抗ｔｒｏｐ‐２抗体と微小管阻害剤、ｐａｒｐ阻害剤、ブルトンキナーゼ阻害剤またはホスホイノシチド３‐キナーゼ阻害剤との併用は癌の治療効果を有意に改善する |
| WO2017053469A2 (en) | 2015-09-21 | 2017-03-30 | Aptevo Research And Development Llc | Cd3 binding polypeptides |
| WO2017161356A1 (en) * | 2016-03-18 | 2017-09-21 | Wake Forest University | Compounds, compositions and associated methods using zirconium-89 in immuno-positron emission tomography |
| US11040973B2 (en) | 2017-03-29 | 2021-06-22 | Purdue Research Foundation | Inhibitors of kinase networks and uses thereof |
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| US2668165A (en) * | 1951-12-22 | 1954-02-02 | American Cyanamid Co | Condensation products of higher fatty acids, polyalkylene polyamines, and organic halides |
| US4468457A (en) | 1981-06-01 | 1984-08-28 | David M. Goldenberg | Method for producing a CSAp tryptic peptide and anti-CSAp antibodies |
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-
2004
- 2004-02-11 US US10/776,470 patent/US7405320B2/en not_active Expired - Fee Related
-
2005
- 2005-02-11 AU AU2005211754A patent/AU2005211754B2/en not_active Ceased
- 2005-02-11 JP JP2006553216A patent/JP5084267B2/ja not_active Expired - Fee Related
- 2005-02-11 CA CA2819492A patent/CA2819492C/en not_active Expired - Fee Related
- 2005-02-11 WO PCT/US2005/004177 patent/WO2005077071A2/en not_active Ceased
- 2005-02-11 EP EP20050726492 patent/EP1720575B1/en not_active Expired - Lifetime
- 2005-02-11 CA CA2555666A patent/CA2555666C/en not_active Expired - Fee Related
-
2008
- 2008-06-12 US US12/138,065 patent/US8158573B2/en not_active Expired - Fee Related
-
2010
- 2010-12-09 AU AU2010249265A patent/AU2010249265C1/en not_active Ceased
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