JP2021500055A5 - - Google Patents
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- JP2021500055A5 JP2021500055A5 JP2020523378A JP2020523378A JP2021500055A5 JP 2021500055 A5 JP2021500055 A5 JP 2021500055A5 JP 2020523378 A JP2020523378 A JP 2020523378A JP 2020523378 A JP2020523378 A JP 2020523378A JP 2021500055 A5 JP2021500055 A5 JP 2021500055A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- cell
- lymphoma
- antibody
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023124386A JP2023139267A (ja) | 2017-10-27 | 2023-07-31 | Ｃｄ１２３に特異的な抗体および抗体－薬物コンジュゲートならびにその使用 |
| JP2024173232A JP2024177330A (ja) | 2017-10-27 | 2024-10-02 | Ｃｄ１２３に特異的な抗体および抗体－薬物コンジュゲートならびにその使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762577922P | 2017-10-27 | 2017-10-27 | |
| US62/577,922 | 2017-10-27 | ||
| PCT/IB2018/058013 WO2019082020A1 (en) | 2017-10-27 | 2018-10-16 | ANTIBODIES AND CONJUGATES CD123-SPECIFIC ANTIBODIES AND USES THEREOF |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023124386A Division JP2023139267A (ja) | 2017-10-27 | 2023-07-31 | Ｃｄ１２３に特異的な抗体および抗体－薬物コンジュゲートならびにその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021500055A JP2021500055A (ja) | 2021-01-07 |
| JP2021500055A5 true JP2021500055A5 (https=) | 2021-11-25 |
| JP7324749B2 JP7324749B2 (ja) | 2023-08-10 |
Family
ID=64109968
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020523378A Active JP7324749B2 (ja) | 2017-10-27 | 2018-10-16 | Ｃｄ１２３に特異的な抗体および抗体－薬物コンジュゲートならびにその使用 |
| JP2023124386A Pending JP2023139267A (ja) | 2017-10-27 | 2023-07-31 | Ｃｄ１２３に特異的な抗体および抗体－薬物コンジュゲートならびにその使用 |
| JP2024173232A Pending JP2024177330A (ja) | 2017-10-27 | 2024-10-02 | Ｃｄ１２３に特異的な抗体および抗体－薬物コンジュゲートならびにその使用 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023124386A Pending JP2023139267A (ja) | 2017-10-27 | 2023-07-31 | Ｃｄ１２３に特異的な抗体および抗体－薬物コンジュゲートならびにその使用 |
| JP2024173232A Pending JP2024177330A (ja) | 2017-10-27 | 2024-10-02 | Ｃｄ１２３に特異的な抗体および抗体－薬物コンジュゲートならびにその使用 |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US11613581B2 (https=) |
| EP (1) | EP3700929A1 (https=) |
| JP (3) | JP7324749B2 (https=) |
| KR (1) | KR102363746B1 (https=) |
| CN (2) | CN119119272A (https=) |
| AU (1) | AU2018357221B2 (https=) |
| BR (1) | BR112020008127A2 (https=) |
| CA (2) | CA3079788C (https=) |
| CO (1) | CO2020005347A2 (https=) |
| IL (1) | IL274095B2 (https=) |
| MX (1) | MX2020004381A (https=) |
| PE (1) | PE20201255A1 (https=) |
| PH (1) | PH12020550596A1 (https=) |
| SA (1) | SA520411849B1 (https=) |
| SG (1) | SG11202003246WA (https=) |
| TW (2) | TWI793513B (https=) |
| WO (1) | WO2019082020A1 (https=) |
| ZA (1) | ZA202002207B (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015015448A2 (en) * | 2013-07-31 | 2015-02-05 | Rinat Neuroscience Corp. | Engineered polypeptide conjugates |
| WO2018119142A1 (en) | 2016-12-21 | 2018-06-28 | Amgen Inc. | Anti-tnf alpha antibody formulations |
| NZ762376A (en) | 2017-09-19 | 2022-08-26 | Scherrer Inst Paul | Transglutaminase conjugation method and linker |
| MX2020004381A (es) | 2017-10-27 | 2020-08-20 | Pfizer | Anticuerpos y conjugados de anticuerpo-farmaco especificos para cd123 y usos de los mismos. |
| SE544015C2 (en) * | 2019-06-18 | 2021-11-02 | Tx Medic Ab | Allogenic car-t cell therapy |
| US20230095053A1 (en) * | 2020-03-03 | 2023-03-30 | Sutro Biopharma, Inc. | Antibodies comprising site-specific glutamine tags, methods of their preparation and methods of their use |
| CN113563470B (zh) * | 2020-04-29 | 2023-02-10 | 广州昂科免疫生物技术有限公司 | 结合tigit抗原的抗体及其制备方法与应用 |
| JP7787101B2 (ja) * | 2020-05-20 | 2025-12-16 | ヤンセン バイオテツク，インコーポレーテツド | グリコシル化Ｆｃドメインを含むタンパク質の部位特異的コンジュゲーションのための方法 |
| KR20230096052A (ko) | 2020-10-25 | 2023-06-29 | 아라리스 바이오테크 아게 | 항체-링커 접합체를 생성하기 위한 수단 및 방법 |
| AU2022282609A1 (en) * | 2021-05-26 | 2023-11-30 | Oxford Biotherapeutics Ltd | Pharmaceutical combination comprising an anti-cd205 antibody and an immune checkpoint inhibitor |
| CN116018351A (zh) * | 2021-08-16 | 2023-04-25 | 上海优替济生生物医药有限公司 | 靶向cd123的抗体、嵌合抗原受体及其用途 |
| WO2023072934A1 (en) * | 2021-10-25 | 2023-05-04 | Araris Biotech Ag | Methods for producing antibody-linker conjugates |
| WO2024123765A1 (en) * | 2022-12-08 | 2024-06-13 | Immunogen, Inc. | Therapeutic combinations comprising anti-cd123 antibody-drug conjugates and anti-cd47 antibodies |
| CN118416247A (zh) * | 2024-04-30 | 2024-08-02 | 上海药明合联生物技术有限公司 | 用于制备具有高d4含量的抗体-药物缀合物（adc）组合物的方法 |
| WO2025227361A1 (en) * | 2024-04-30 | 2025-11-06 | Wuxi Xdc (Shanghai) Co., Ltd. | Process for preparing a composition of antibody-drug conjugates (adcs) with high d4 content |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| US4485045A (en) | 1981-07-06 | 1984-11-27 | Research Corporation | Synthetic phosphatidyl cholines useful in forming liposomes |
| US4544545A (en) | 1983-06-20 | 1985-10-01 | Trustees University Of Massachusetts | Liposomes containing modified cholesterol for organ targeting |
| US4754065A (en) | 1984-12-18 | 1988-06-28 | Cetus Corporation | Precursor to nucleic acid probe |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| GB8601597D0 (en) | 1986-01-23 | 1986-02-26 | Wilson R H | Nucleotide sequences |
| US4800159A (en) | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
| US5013556A (en) | 1989-10-20 | 1991-05-07 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| US5981568A (en) | 1993-01-28 | 1999-11-09 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| US5663149A (en) | 1994-12-13 | 1997-09-02 | Arizona Board Of Regents Acting On Behalf Of Arizona State University | Human cancer inhibitory pentapeptide heterocyclic and halophenyl amides |
| GB9809951D0 (en) | 1998-05-08 | 1998-07-08 | Univ Cambridge Tech | Binding molecules |
| WO2000053211A2 (en) | 1999-03-09 | 2000-09-14 | University Of Southern California | Method of promoting myocyte proliferation and myocardial tissue repair |
| US8163279B2 (en) | 2007-04-13 | 2012-04-24 | Stemline Therapeutics, Inc. | IL3Rα antibody conjugates and uses thereof |
| JP5694923B2 (ja) * | 2009-04-27 | 2015-04-01 | 協和発酵キリン株式会社 | 血液腫瘍治療を目的とした抗ＩＬ−３Ｒα抗体 |
| CA2813411C (en) | 2010-11-05 | 2016-08-02 | Rinat Neuroscience Corporation | Engineered polypeptide conjugates and methods for making thereof using transglutaminase |
| JP6072771B2 (ja) | 2011-04-20 | 2017-02-01 | メディミューン，エルエルシー | Ｂ７−ｈ１およびｐｄ−１に結合する抗体およびその他の分子 |
| CN104185477B (zh) | 2011-11-17 | 2017-05-24 | 辉瑞公司 | 细胞毒性肽及其抗体‑药物缀合物 |
| WO2015015448A2 (en) | 2013-07-31 | 2015-02-05 | Rinat Neuroscience Corp. | Engineered polypeptide conjugates |
| SG11201605437YA (en) * | 2014-01-27 | 2016-08-30 | Pfizer | Bifunctional cytotoxic agents |
| PT3134127T (pt) * | 2014-04-25 | 2020-04-09 | Rinat Neuroscience Corp | Conjugados de anticorpo-fármaco com alta carga de fármaco |
| MA40609B1 (fr) * | 2014-09-05 | 2020-05-29 | Janssen Pharmaceutica Nv | Agents de liaison cd123 et leurs utilisations |
| CN120988137A (zh) * | 2015-01-23 | 2025-11-21 | 赛诺菲 | 抗cd3抗体、抗cd123抗体和与cd3和/或cd123特异性结合的双特异性抗体 |
| TW201709932A (zh) * | 2015-06-12 | 2017-03-16 | 西雅圖遺傳學公司 | Ｃｄ１２３抗體及其共軛物 |
| JP6768011B2 (ja) * | 2015-06-23 | 2020-10-14 | バイエル ファーマ アクチエンゲゼルシャフト | キネシンスピンドルタンパク質（ｋｓｐ）阻害剤の抗ｃｄ１２３抗体との抗体薬物複合体 |
| AU2016285552B2 (en) * | 2015-06-29 | 2022-10-13 | Immunogen, Inc. | Anti-CD123 antibodies and conjugates and derivatives thereof |
| US11976121B2 (en) * | 2017-07-20 | 2024-05-07 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | CD123-binding chimeric antigen receptors |
| MX2020004381A (es) | 2017-10-27 | 2020-08-20 | Pfizer | Anticuerpos y conjugados de anticuerpo-farmaco especificos para cd123 y usos de los mismos. |
-
2018
- 2018-10-16 MX MX2020004381A patent/MX2020004381A/es unknown
- 2018-10-16 CA CA3079788A patent/CA3079788C/en active Active
- 2018-10-16 IL IL274095A patent/IL274095B2/en unknown
- 2018-10-16 CN CN202411219753.1A patent/CN119119272A/zh active Pending
- 2018-10-16 KR KR1020207014653A patent/KR102363746B1/ko active Active
- 2018-10-16 WO PCT/IB2018/058013 patent/WO2019082020A1/en not_active Ceased
- 2018-10-16 CA CA3205442A patent/CA3205442A1/en active Pending
- 2018-10-16 PE PE2020000682A patent/PE20201255A1/es unknown
- 2018-10-16 CN CN201880069901.2A patent/CN111556876B/zh active Active
- 2018-10-16 US US16/758,124 patent/US11613581B2/en active Active
- 2018-10-16 AU AU2018357221A patent/AU2018357221B2/en active Active
- 2018-10-16 SG SG11202003246WA patent/SG11202003246WA/en unknown
- 2018-10-16 JP JP2020523378A patent/JP7324749B2/ja active Active
- 2018-10-16 EP EP18797140.3A patent/EP3700929A1/en active Pending
- 2018-10-16 BR BR112020008127-2A patent/BR112020008127A2/pt unknown
- 2018-10-24 TW TW110103347A patent/TWI793513B/zh active
- 2018-10-24 TW TW107137519A patent/TWI718427B/zh active
-
2020
- 2020-04-27 SA SA520411849A patent/SA520411849B1/ar unknown
- 2020-04-28 CO CONC2020/0005347A patent/CO2020005347A2/es unknown
- 2020-04-29 PH PH12020550596A patent/PH12020550596A1/en unknown
- 2020-05-04 ZA ZA2020/02207A patent/ZA202002207B/en unknown
-
2023
- 2023-03-08 US US18/180,704 patent/US20230357417A1/en not_active Abandoned
- 2023-07-31 JP JP2023124386A patent/JP2023139267A/ja active Pending
-
2024
- 2024-10-02 JP JP2024173232A patent/JP2024177330A/ja active Pending
- 2024-12-03 US US18/967,173 patent/US20250154270A1/en active Pending
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