JP2007515487A - カリウムイブプロフェンの高度に濃厚な注入可能水溶液、それらの調製及びそれらの使用 - Google Patents
カリウムイブプロフェンの高度に濃厚な注入可能水溶液、それらの調製及びそれらの使用 Download PDFInfo
- Publication number
- JP2007515487A JP2007515487A JP2006547093A JP2006547093A JP2007515487A JP 2007515487 A JP2007515487 A JP 2007515487A JP 2006547093 A JP2006547093 A JP 2006547093A JP 2006547093 A JP2006547093 A JP 2006547093A JP 2007515487 A JP2007515487 A JP 2007515487A
- Authority
- JP
- Japan
- Prior art keywords
- composition
- ibuprofen
- potassium
- weight
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/744,545 US20050137262A1 (en) | 2003-12-22 | 2003-12-22 | Highly concentrated pourable aqueous solutions of potassium ibuprofen, their preparation and their uses |
| PCT/US2004/041584 WO2005065665A2 (en) | 2003-12-22 | 2004-12-13 | Highly concentrated pourable aqueous solutions of potassium ibuprofen, their preparation and their uses |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007515487A true JP2007515487A (ja) | 2007-06-14 |
| JP2007515487A5 JP2007515487A5 (enExample) | 2008-02-07 |
Family
ID=34678897
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006547093A Pending JP2007515487A (ja) | 2003-12-22 | 2004-12-13 | カリウムイブプロフェンの高度に濃厚な注入可能水溶液、それらの調製及びそれらの使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20050137262A1 (enExample) |
| EP (2) | EP1696891A2 (enExample) |
| JP (1) | JP2007515487A (enExample) |
| KR (1) | KR20060123378A (enExample) |
| CN (1) | CN1897925A (enExample) |
| CA (1) | CA2549731A1 (enExample) |
| WO (1) | WO2005065665A2 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060088590A1 (en) * | 2004-10-22 | 2006-04-27 | Banner Pharmacaps, Inc. | Non-blooming gelatin and non-gelatin formulations |
| US8231896B2 (en) | 2004-11-08 | 2012-07-31 | R.P. Scherer Technologies, Llc | Non-gelatin soft capsule system |
| WO2007035448A2 (en) * | 2005-09-19 | 2007-03-29 | Albemarle Corporation | Highly concentrated pourable aqueous solutions of potassium ibuprofen their preparation and their uses |
| US9629809B2 (en) | 2008-07-21 | 2017-04-25 | Si Group, Inc. | High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms |
| BRPI0916344A2 (pt) * | 2008-07-21 | 2020-07-21 | Albemarle Corporation | grânulos com alto teor de ibuprofeno de sódio, preparação e utilização para preparação de formas de dosagem sólidas não efervescentes |
| KR101599459B1 (ko) | 2015-02-05 | 2016-03-14 | 주식회사 네오셈 | 반도체 소자 테스트 시스템 및 방법 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH01502185A (ja) * | 1986-10-17 | 1989-08-03 | アール ピー シーラー コーポレーション | 医薬品のカプセル化の簡易化 |
| JPH03502800A (ja) * | 1988-03-25 | 1991-06-27 | オラテク・ファーマセウティカル・デベロプメント・コーポレーション | 水溶性イブプロフェン組成物及びその製造方法 |
| JPH05310566A (ja) * | 1991-12-19 | 1993-11-22 | Rp Scherer Corp | カプセルに封入する溶媒系 |
| WO2003075909A1 (en) * | 2002-03-11 | 2003-09-18 | Warner-Lambert Company Llc | Ibuprofen solution for hard shell capsules |
Family Cites Families (91)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB971700A (en) * | 1961-02-02 | 1964-09-30 | Boots Pure Drug Co Ltd | Anti-Inflammatory Agents |
| DE2231426C3 (de) * | 1972-06-27 | 1974-11-28 | Motoren- Und Turbinen-Union Muenchen Gmbh, 8000 Muenchen | Deckbandlose, innen gekühlte Axialturbinenlaufschaufel |
| US3987094A (en) * | 1974-12-10 | 1976-10-19 | The Upjohn Company | Preparing carboxylic acids from glycidonitriles |
| US4189596A (en) * | 1976-05-24 | 1980-02-19 | The Upjohn Company | Preparing 2-arylalkanoic acid derivatives |
| US4145440A (en) * | 1977-08-18 | 1979-03-20 | The Upjohn Company | Liquid suspension of an aluminum salt of ibuprofen |
| IT1209145B (it) * | 1979-11-23 | 1989-07-10 | Resfar Srl | Procedimento per migliorare le caratteristiche farmacologiche degli acidi aril-alcanoici adattivita' analgesica e anti-infiammatoria. |
| US4282252A (en) * | 1980-05-15 | 1981-08-04 | Thomas Jefferson University | Method of increasing coronary blood flow with ibuprofen |
| US4346108A (en) * | 1981-06-22 | 1982-08-24 | The Upjohn Manufacturing Company M | Method for preventing adhesion formation |
| US4447451A (en) * | 1981-07-20 | 1984-05-08 | The Upjohn Manufacturing Company M | Treatment of adult respiratory distress syndrome |
| US4404210A (en) * | 1982-06-30 | 1983-09-13 | E. I. Du Pont De Nemours And Company | Analgesic mixture of nalbuphine and ibuprofen |
| US4623736A (en) * | 1982-07-09 | 1986-11-18 | The Upjohn Company | Arylalkanoic acid process improvement |
| US4447443A (en) * | 1982-11-15 | 1984-05-08 | Merck & Co., Inc. | Anti-inflammatory/analgesic combination of α-fluoromethylhistidine and a selected non-steroidal anti-inflammatory drug (NSAID) |
| US4476248A (en) * | 1983-02-28 | 1984-10-09 | The Upjohn Company | Crystallization of ibuprofen |
| US4439450A (en) * | 1983-06-30 | 1984-03-27 | The Upjohn Manufacturing Company M | Treatment of the blood-brain barrier with ibuprofen |
| US4558051A (en) * | 1983-10-11 | 1985-12-10 | Richardson-Vicks, Inc. | Analgesic and anti-inflammatory compositions comprising xanthines and methods of using same |
| US4552899A (en) * | 1984-04-09 | 1985-11-12 | Analgesic Associates | Cough/cold mixtures comprising non-steroidal anti-inflammatory drugs |
| IE58110B1 (en) * | 1984-10-30 | 1993-07-14 | Elan Corp Plc | Controlled release powder and process for its preparation |
| FR2573753B1 (fr) * | 1984-11-29 | 1987-03-20 | Sanofi Sa | Procede de preparation d'a-hydroxy-acides et composes obtenus par ce procede |
| FR2573754B1 (fr) * | 1984-11-29 | 1987-02-27 | Sanofi Sa | Procede de preparation d'acides a-hydroxyphenylalcanoiques et composes obtenus par ce procede |
| US4569937A (en) * | 1985-02-11 | 1986-02-11 | E. I. Du Pont De Nemours And Company | Analgesic mixture of oxycodone and ibuprofen |
| CA1280414C (en) * | 1985-03-15 | 1991-02-19 | Saichi Matsumoto | Isoprenoidamine derivatives and antiulcer agents |
| US4687662A (en) * | 1985-08-30 | 1987-08-18 | Warner-Lambert Company | Therapeutic effervescent composition |
| GB8528195D0 (en) * | 1985-11-15 | 1985-12-18 | Boots Co Plc | Therapeutic compositions |
| JPH064561B2 (ja) * | 1986-02-08 | 1994-01-19 | 日本石油化学株式会社 | (置換アリ−ル)カルボン酸の製造方法 |
| US4761274A (en) * | 1986-03-27 | 1988-08-02 | Warner-Lambert Company | Medicament adsorbates of analgesics with complex magnesium aluminum silicate and their preparation |
| US4843099A (en) * | 1987-07-20 | 1989-06-27 | Colgate-Palmolive Company | Device and composition for treatment of the gums |
| US4861797A (en) * | 1987-10-15 | 1989-08-29 | Oratech Pharmaceutical Development Corporation | Liquid ibuprofen compositions and methods of making them |
| US5198568A (en) * | 1988-04-07 | 1993-03-30 | Sepracor, Inc. | Compounds useful in enzymatic resolution systems and their preparation |
| EP0336031A1 (en) * | 1988-04-07 | 1989-10-11 | Council of Scientific and Industrial Research | Process for the photochemical production of alpha-aryl propionic acid |
| GB8813682D0 (en) * | 1988-06-09 | 1988-07-13 | Reckitt & Colmann Prod Ltd | Pharmaceutical compositions |
| US4916161A (en) * | 1988-10-25 | 1990-04-10 | Bristol-Myers Squibb | Taste-masking pharmaceutical agents |
| DE3838431A1 (de) * | 1988-11-12 | 1990-05-17 | Bayer Ag | Ibuprofen-brausezubereitungen |
| US5007790A (en) * | 1989-04-11 | 1991-04-16 | Depomed Systems, Inc. | Sustained-release oral drug dosage form |
| US5266723A (en) * | 1989-05-16 | 1993-11-30 | Medice, Ltd., Chem.-Pharm. Fabrik Putter Gmbh & Co. Kg | Process for the preparation of optically active 2-aryl-alkanoic acids, especially 2-aryl-propionic acids |
| US5262179A (en) * | 1989-09-13 | 1993-11-16 | Nicholas Kiwi Pty Ltd. | Non-effervescent ibuprofen compositions |
| US5015764A (en) * | 1990-06-18 | 1991-05-14 | Ethyl Corporation | Preparation of optically active aliphatic carboxylic acids |
| US5183829A (en) * | 1991-09-27 | 1993-02-02 | Applied Analytical Industries, Inc. | Oral liquid compositions of non-steroidal anti-inflammatory drugs |
| US5235100A (en) * | 1992-01-24 | 1993-08-10 | Ethyl Corporation | Preparation of optically active aliphatic carboxylic acids |
| US5235101A (en) * | 1992-01-24 | 1993-08-10 | Ethyl Corporation | Preparation by flotation of optically active aliphatic carboxylic acids |
| US5235095A (en) * | 1992-01-24 | 1993-08-10 | Ethyl Corporation | Preparation of optically active aliphatic carboxylic acids |
| US5512300A (en) * | 1992-09-15 | 1996-04-30 | Warner-Lambert Company | Prevention of ibuprofen from forming low melting eutectics with other therapeutic agents in solid dosage forms |
| US5278337A (en) * | 1992-10-14 | 1994-01-11 | Ethyl Corporation | Enantiomeric resolution of aryl-substituted aliphatic carboxylic acids |
| US5248813A (en) * | 1992-10-14 | 1993-09-28 | Ethyl Corporation | Enantiomeric resolution |
| ATE180668T1 (de) * | 1992-12-01 | 1999-06-15 | Spirig Ag | S(+)-ibuprofen enthaltende arzneimittel |
| US5376688A (en) * | 1992-12-18 | 1994-12-27 | R. P. Scherer Corporation | Enhanced solubility pharmaceutical solutions |
| IT1272149B (it) * | 1993-03-26 | 1997-06-11 | Zambon Spa | Composizione farmeceutiche ad attivita' analgesica |
| IT1264856B1 (it) * | 1993-06-21 | 1996-10-17 | Zambon Spa | Composizione farmaceutica ad attivita' analgesica |
| US5866162A (en) * | 1993-08-10 | 1999-02-02 | Smithkline Beecham P.L.C. | Pharmaceutical composition containing a drug/β-cyclodextrin complex in combination with an acid-base couple |
| US6149953A (en) * | 1993-11-08 | 2000-11-21 | Delta Food Group, Inc. | Seeded microcapsules |
| US20020048596A1 (en) * | 1994-12-30 | 2002-04-25 | Gregor Cevc | Preparation for the transport of an active substance across barriers |
| US5616621A (en) * | 1995-01-30 | 1997-04-01 | American Home Products Corporation | Taste masking liquids |
| WO1996031218A1 (en) * | 1995-04-03 | 1996-10-10 | Chugai Seiyaku Kabushiki Kaisha | Pharmaceutical composition containing sucralfate |
| US6214386B1 (en) * | 1995-11-22 | 2001-04-10 | Recordati, S.A. | Prompt-release oral pharmaceutical compositions for extemporaneous suspensions |
| US5900416A (en) * | 1996-02-01 | 1999-05-04 | Anthea Enterprises Incorporated | Aqueous caffeine dosage forms |
| AUPN969796A0 (en) * | 1996-05-07 | 1996-05-30 | F.H. Faulding & Co. Limited | Taste masked liquid suspensions |
| US5827535A (en) * | 1996-06-21 | 1998-10-27 | Banner Pharmacaps, Inc. | Graphically impressed softgel and method for making same |
| US5766622A (en) * | 1996-08-14 | 1998-06-16 | The Procter & Gamble Company | Inhibiting undesirable taste in oral compositions |
| ATE197900T1 (de) * | 1996-08-15 | 2000-12-15 | Losan Pharma Gmbh | Gut schluckbare orale arzneiform |
| US6767925B1 (en) * | 1996-10-31 | 2004-07-27 | Joseph A. Deihl | Sprayable analgesic composition and method of use |
| US6472000B1 (en) * | 1996-12-23 | 2002-10-29 | Wm. Wrigley Jr. Co. | Method of controlling release of bitterness inhibitors in chewing gum and gum produced thereby |
| US5759579A (en) * | 1996-12-05 | 1998-06-02 | American Home Products Corporation | Pharmaceutical suspension systems |
| US6071543A (en) * | 1997-06-02 | 2000-06-06 | Cellegy Pharmaceuticals, Inc. | Pyridine-thiols reverse mucocutaneous aging |
| US6197327B1 (en) * | 1997-06-11 | 2001-03-06 | Umd, Inc. | Device and method for treatment of dysmenorrhea |
| US7303768B2 (en) * | 1998-07-24 | 2007-12-04 | Seo Hong Yoo | Preparation of aqueous clear solution dosage forms with bile acids |
| IT1301966B1 (it) * | 1998-07-30 | 2000-07-20 | Zambon Spa | Composizioni farmaceutiche ad attivita' analgesica |
| US6596298B2 (en) * | 1998-09-25 | 2003-07-22 | Warner-Lambert Company | Fast dissolving orally comsumable films |
| US20030138499A1 (en) * | 1998-12-17 | 2003-07-24 | Shah Mandar V. | Stable surgical irrigating solutions |
| US6383471B1 (en) * | 1999-04-06 | 2002-05-07 | Lipocine, Inc. | Compositions and methods for improved delivery of ionizable hydrophobic therapeutic agents |
| US6309663B1 (en) * | 1999-08-17 | 2001-10-30 | Lipocine Inc. | Triglyceride-free compositions and methods for enhanced absorption of hydrophilic therapeutic agents |
| US6340473B1 (en) * | 1999-07-07 | 2002-01-22 | R.P. Scherer Technologies, Inc. | Film forming compositions comprising modified starches and iota-carrageenan and methods for manufacturing soft capsules using same |
| US6251426B1 (en) * | 1999-09-02 | 2001-06-26 | Banner Pharmacaps, Inc. | Ibuprofen-containing softgels |
| ES2288872T3 (es) * | 1999-09-29 | 2008-02-01 | R.P. Scherer Technologies, Inc. | Granulaciones con celulosa hidrolizada de sales de medicamentos. |
| US20030124176A1 (en) * | 1999-12-16 | 2003-07-03 | Tsung-Min Hsu | Transdermal and topical administration of drugs using basic permeation enhancers |
| US6586000B2 (en) * | 1999-12-16 | 2003-07-01 | Dermatrends, Inc. | Hydroxide-releasing agents as skin permeation enhancers |
| US20030104041A1 (en) * | 1999-12-16 | 2003-06-05 | Tsung-Min Hsu | Transdermal and topical administration of drugs using basic permeation enhancers |
| AU2001257511A1 (en) * | 2000-05-03 | 2001-11-12 | Joe D'silva | Process and device for producing liquid dosage formulations |
| DE10027258C1 (de) * | 2000-05-31 | 2001-10-31 | Lohmann Therapie Syst Lts | Transdermales therapeutisches System mit okklusiver wirkstoffhaltiger Schicht und nicht-okklusiver Rückschicht |
| US20040022787A1 (en) * | 2000-07-03 | 2004-02-05 | Robert Cohen | Methods for treating an autoimmune disease using a soluble CTLA4 molecule and a DMARD or NSAID |
| US6387400B1 (en) * | 2000-08-29 | 2002-05-14 | R.P. Scherer Technologies, Inc. | Process for preparing pharmaceutical compositions for use with soft gelatin formulations |
| DE10103860B4 (de) * | 2001-01-30 | 2004-12-23 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System für die Verabreichung carboxylgruppenhaltiger, nichtsteroidaler Antiphlogistika, sowie Verfahren zu seiner Herstellung |
| ITRM20010048A1 (it) * | 2001-01-30 | 2002-07-30 | Gregorio Mauro De | Metodo per preparare soluzioni acquose fisiologicamente accettabili esoluzioni cosi' ottenute. |
| CA2410469A1 (en) * | 2001-03-27 | 2002-10-03 | R.P. Scherer Technologies, Inc. | Improved forms of pharmaceutically active agents and method for manufacture thereof |
| GB0108082D0 (en) * | 2001-03-30 | 2001-05-23 | Novartis Consumer Health Sa | Topical composition |
| US20020182600A1 (en) * | 2001-04-11 | 2002-12-05 | Smith Jack V. | Method for assaying biological and other constituents using synthetic nucleounits in lateral flow, liquid, and dry chemistry techniques |
| US6551615B1 (en) * | 2001-10-18 | 2003-04-22 | M/S. Strides Arcolab Limited | Dexibuprofen-containing soft gelatin capsules and process for preparing the same |
| US7004171B2 (en) * | 2002-02-25 | 2006-02-28 | Hi-Gienic Intra Vaginal Technologies Ltd. | System for transvaginal drug delivery |
| WO2003099264A1 (en) * | 2002-05-23 | 2003-12-04 | Umd, Inc. | Compositions and method for transmucosal drug delivery and cryoprotection |
| US20030022390A1 (en) * | 2002-05-30 | 2003-01-30 | Stephens James Matthew | Method and kit for making interfering substances in urine undetectable |
| US7008763B2 (en) * | 2002-09-23 | 2006-03-07 | Cheung David T | Method to treat collagenous connective tissue for implant remodeled by host cells into living tissue |
| US7166641B2 (en) * | 2002-10-02 | 2007-01-23 | Yung Shin Pharmaceutical Industrial Co., Ltd. | Pharmaceutically acceptable salts containing local anesthetic and anti-inflammatory activities and methods for preparing the same |
| US20040147534A1 (en) * | 2003-01-23 | 2004-07-29 | Foote Mary Ann | Topical composition and method for treating occlusive wounds |
-
2003
- 2003-12-22 US US10/744,545 patent/US20050137262A1/en not_active Abandoned
-
2004
- 2004-12-13 CA CA002549731A patent/CA2549731A1/en not_active Abandoned
- 2004-12-13 EP EP04813842A patent/EP1696891A2/en not_active Withdrawn
- 2004-12-13 KR KR1020067012547A patent/KR20060123378A/ko not_active Withdrawn
- 2004-12-13 JP JP2006547093A patent/JP2007515487A/ja active Pending
- 2004-12-13 WO PCT/US2004/041584 patent/WO2005065665A2/en not_active Ceased
- 2004-12-13 CN CNA200480038266XA patent/CN1897925A/zh active Pending
- 2004-12-13 EP EP09014697A patent/EP2156825A1/en not_active Withdrawn
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH01502185A (ja) * | 1986-10-17 | 1989-08-03 | アール ピー シーラー コーポレーション | 医薬品のカプセル化の簡易化 |
| JPH03502800A (ja) * | 1988-03-25 | 1991-06-27 | オラテク・ファーマセウティカル・デベロプメント・コーポレーション | 水溶性イブプロフェン組成物及びその製造方法 |
| JPH05310566A (ja) * | 1991-12-19 | 1993-11-22 | Rp Scherer Corp | カプセルに封入する溶媒系 |
| WO2003075909A1 (en) * | 2002-03-11 | 2003-09-18 | Warner-Lambert Company Llc | Ibuprofen solution for hard shell capsules |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2549731A1 (en) | 2005-07-21 |
| US20050137262A1 (en) | 2005-06-23 |
| CN1897925A (zh) | 2007-01-17 |
| WO2005065665A3 (en) | 2005-11-24 |
| KR20060123378A (ko) | 2006-12-01 |
| EP1696891A2 (en) | 2006-09-06 |
| WO2005065665A2 (en) | 2005-07-21 |
| EP2156825A1 (en) | 2010-02-24 |
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