JP2007515411A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2007515411A5 JP2007515411A5 JP2006542866A JP2006542866A JP2007515411A5 JP 2007515411 A5 JP2007515411 A5 JP 2007515411A5 JP 2006542866 A JP2006542866 A JP 2006542866A JP 2006542866 A JP2006542866 A JP 2006542866A JP 2007515411 A5 JP2007515411 A5 JP 2007515411A5
- Authority
- JP
- Japan
- Prior art keywords
- dimethylamino
- dioxo
- trihydroxy
- oxazole
- carboxamide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 C[C@@]([C@](C[C@]1(*)C*2c(*)c(*)c(*C(C*(*)*)=O)c(O)c22)([C@]3(*)C(*)=C1C2=O)I)C(*)=C(C(*)=C)C3=* Chemical compound C[C@@]([C@](C[C@]1(*)C*2c(*)c(*)c(*C(C*(*)*)=O)c(O)c22)([C@]3(*)C(*)=C1C2=O)I)C(*)=C(C(*)=C)C3=* 0.000 description 3
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US52792803P | 2003-12-08 | 2003-12-08 | |
| US60/527,928 | 2003-12-08 | ||
| US58482304P | 2004-07-01 | 2004-07-01 | |
| US60/584,823 | 2004-07-01 | ||
| PCT/US2004/040850 WO2005056538A1 (en) | 2003-12-08 | 2004-12-07 | Oxazole derivatives of tetracyclines |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007515411A JP2007515411A (ja) | 2007-06-14 |
| JP2007515411A5 true JP2007515411A5 (https=) | 2011-10-20 |
| JP4848287B2 JP4848287B2 (ja) | 2011-12-28 |
Family
ID=34681543
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006542866A Expired - Fee Related JP4848287B2 (ja) | 2003-12-08 | 2004-12-07 | テトラサイクリンのオキサゾール誘導体 |
Country Status (25)
| Country | Link |
|---|---|
| US (3) | US7176225B2 (https=) |
| EP (2) | EP1692117B1 (https=) |
| JP (1) | JP4848287B2 (https=) |
| KR (1) | KR101164262B1 (https=) |
| CN (1) | CN100545151C (https=) |
| AR (1) | AR047274A1 (https=) |
| AT (2) | ATE525365T1 (https=) |
| AU (1) | AU2004297243B2 (https=) |
| BR (1) | BRPI0417421A (https=) |
| CA (1) | CA2546895A1 (https=) |
| CO (1) | CO5700818A2 (https=) |
| CR (1) | CR8437A (https=) |
| DE (1) | DE602004023417D1 (https=) |
| EC (1) | ECSP066605A (https=) |
| ES (2) | ES2331574T3 (https=) |
| IL (2) | IL176162A (https=) |
| MY (1) | MY146098A (https=) |
| NO (1) | NO20062629L (https=) |
| PA (1) | PA8619601A1 (https=) |
| PE (1) | PE20050995A1 (https=) |
| RU (1) | RU2415844C2 (https=) |
| SG (1) | SG148216A1 (https=) |
| TW (1) | TW200528437A (https=) |
| UA (2) | UA83266C2 (https=) |
| WO (1) | WO2005056538A1 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2892332C (en) * | 2004-05-21 | 2017-03-21 | President And Fellows Of Harvard College | Synthesis of tetracyclines and analogues thereof |
| AU2005299294B2 (en) | 2004-10-25 | 2012-06-07 | Paratek Pharmaceuticals, Inc. | 4-aminotetracyclines and methods of use thereof |
| AR057324A1 (es) * | 2005-05-27 | 2007-11-28 | Wyeth Corp | Tigeciclina y metodos para preparar 9-aminominociclina |
| AR057033A1 (es) * | 2005-05-27 | 2007-11-14 | Wyeth Corp | Tigeciclina y metodos para preparar 9-nitrominociclina |
| AR057032A1 (es) * | 2005-05-27 | 2007-11-14 | Wyeth Corp | Tigeciclina y metodos de preparacion |
| JP2009502809A (ja) * | 2005-07-21 | 2009-01-29 | パラテック ファーマシューティカルズ インコーポレイテッド | １０−置換テトラサイクリンおよびその使用方法 |
| JP5335664B2 (ja) | 2006-04-07 | 2013-11-06 | プレジデント アンド フェロウズ オブ ハーバード カレッジ | テトラサイクリンおよびその類似体の合成 |
| WO2008127361A2 (en) | 2006-10-11 | 2008-10-23 | President And Fellows Of Harvard College | Synthesis of enone intermediate |
| WO2008045507A2 (en) | 2006-10-11 | 2008-04-17 | Paratek Pharmaceuticals, Inc. | Substituted tetracycline compounds for treatment of bacillus anthracis infections |
| US8121767B2 (en) * | 2007-11-02 | 2012-02-21 | GM Global Technology Operations LLC | Predicted and immediate output torque control architecture for a hybrid powertrain system |
| SI2220033T1 (sl) | 2007-11-14 | 2015-07-31 | Sandoz Ag | Kristalna oblika tigeciklin hidroklorida |
| CA2730377C (en) | 2008-07-11 | 2017-09-19 | Neumedics | Tetracycline derivatives with reduced antibiotic activity and neuroprotective benefits |
| US8513224B2 (en) | 2008-12-18 | 2013-08-20 | Sandoz Ag | Crystalline form C of tigecycline dihydrochloride and methods for its preparation |
| WO2010126607A2 (en) | 2009-04-30 | 2010-11-04 | President And Fellows Of Harvard College | Synthesis of tetracyclines and intermediates thereto |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US26253A (en) * | 1859-11-29 | Vegetable-cutter | ||
| US2482055A (en) | 1948-02-11 | 1949-09-13 | American Cyanamid Co | Aureomycin and preparation of same |
| US3007965A (en) | 1959-02-13 | 1961-11-07 | American Cyanamid Co | New tetracyclines produced by streptomyces aureofaciens |
| US3043875A (en) | 1959-10-22 | 1962-07-10 | Pfizer & Co C | Halogenated tetracycline derivatives and processes for their preparation |
| FR1430859A (https=) | 1960-05-23 | 1966-05-25 | ||
| US3338963A (en) | 1960-10-28 | 1967-08-29 | American Cyanamid Co | Tetracycline compounds |
| US3148212A (en) | 1961-12-22 | 1964-09-08 | American Cyanamid Co | Reductive alkylation process |
| US3360557A (en) | 1963-05-10 | 1967-12-26 | American Cyanamid Co | 9-hydroxytetracyclines and a process of preparing same |
| USRE26253E (en) | 1963-05-17 | 1967-08-15 | And z-alkylamino-g-deoxytetracycline | |
| US3341585A (en) | 1966-05-06 | 1967-09-12 | American Cyanamid Co | Substituted 7-and/or 9-amino-6-deoxytetracyclines |
| US3360561A (en) | 1967-06-19 | 1967-12-26 | American Cyanamid Co | Nitration of tetracyclines |
| US3518306A (en) | 1968-02-19 | 1970-06-30 | American Cyanamid Co | 7- and/or 9-(n-nitrosoalkylamino)-6-demethyl-6-deoxytetracyclines |
| US4806529A (en) | 1982-11-18 | 1989-02-21 | Trustees Of Tufts College, Tufts University | Tetracycline activity enhancement |
| DE122006000058I1 (de) * | 1991-10-04 | 2007-01-18 | Wyeth Corp | 7-Substituierte-9-substituierte Amino-6-Demethyl-6-Deoxy-Tetracycline |
| US5494903A (en) | 1991-10-04 | 1996-02-27 | American Cyanamid Company | 7-substituted-9-substituted amino-6-demethyl-6-deoxytetracyclines |
| US5328902A (en) * | 1992-08-13 | 1994-07-12 | American Cyanamid Co. | 7-(substituted)-9-[(substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines |
| MXPA02001471A (es) * | 1999-08-10 | 2002-07-02 | Smithkline Beecham Corp | 4,4-diaril ciclohexanos 1,4-substituidos. |
| EP2329826A1 (en) * | 2001-07-13 | 2011-06-08 | Paratek Pharmaceuticals, Inc. | Tetracyclines for the treatment of multiple sclerosis |
-
2004
- 2004-07-12 UA UAA200606344A patent/UA83266C2/ru unknown
- 2004-10-30 UA UAA200606646A patent/UA83268C2/ru unknown
- 2004-12-01 TW TW093137032A patent/TW200528437A/zh unknown
- 2004-12-07 MY MYPI20045049A patent/MY146098A/en unknown
- 2004-12-07 JP JP2006542866A patent/JP4848287B2/ja not_active Expired - Fee Related
- 2004-12-07 RU RU2006118367/04A patent/RU2415844C2/ru not_active IP Right Cessation
- 2004-12-07 EP EP04813199A patent/EP1692117B1/en not_active Expired - Lifetime
- 2004-12-07 ES ES04813199T patent/ES2331574T3/es not_active Expired - Lifetime
- 2004-12-07 PA PA20048619601A patent/PA8619601A1/es unknown
- 2004-12-07 PE PE2004001203A patent/PE20050995A1/es not_active Application Discontinuation
- 2004-12-07 AR ARP040104570A patent/AR047274A1/es unknown
- 2004-12-07 AU AU2004297243A patent/AU2004297243B2/en not_active Ceased
- 2004-12-07 SG SG200809014-4A patent/SG148216A1/en unknown
- 2004-12-07 CN CNB2004800364939A patent/CN100545151C/zh not_active Expired - Fee Related
- 2004-12-07 AT AT09010915T patent/ATE525365T1/de not_active IP Right Cessation
- 2004-12-07 KR KR1020067013606A patent/KR101164262B1/ko not_active Expired - Fee Related
- 2004-12-07 BR BRPI0417421-6A patent/BRPI0417421A/pt not_active IP Right Cessation
- 2004-12-07 CA CA002546895A patent/CA2546895A1/en not_active Abandoned
- 2004-12-07 ES ES09010915T patent/ES2372635T3/es not_active Expired - Lifetime
- 2004-12-07 EP EP09010915A patent/EP2157085B1/en not_active Expired - Lifetime
- 2004-12-07 WO PCT/US2004/040850 patent/WO2005056538A1/en not_active Ceased
- 2004-12-07 AT AT04813199T patent/ATE444290T1/de not_active IP Right Cessation
- 2004-12-07 DE DE602004023417T patent/DE602004023417D1/de not_active Expired - Lifetime
- 2004-12-08 US US11/007,621 patent/US7176225B2/en not_active Expired - Fee Related
-
2006
- 2006-06-05 EC EC2006006605A patent/ECSP066605A/es unknown
- 2006-06-06 IL IL176162A patent/IL176162A/en not_active IP Right Cessation
- 2006-06-06 CR CR8437A patent/CR8437A/es not_active Application Discontinuation
- 2006-06-08 CO CO06055450A patent/CO5700818A2/es unknown
- 2006-06-08 NO NO20062629A patent/NO20062629L/no not_active Application Discontinuation
- 2006-12-13 US US11/638,138 patent/US7365087B2/en not_active Expired - Fee Related
-
2008
- 2008-03-24 US US12/053,856 patent/US20080177080A1/en not_active Abandoned
-
2010
- 2010-05-27 IL IL206050A patent/IL206050A/en not_active IP Right Cessation
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2007515411A5 (https=) | ||
| JP6986045B2 (ja) | キナーゼを修飾する１ｈ−ピロロ［２，３−ｂ］ピリジン誘導体の合成 | |
| JP2010138190A5 (https=) | ||
| CA2879151C (en) | Processes for the preparation of (s)-3-(4-((4-(morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione and pharmaceutically acceptable forms thereof | |
| RU2012112050A (ru) | Производные дигидроптеридинона, способ их получения и фармацевтическое применение | |
| JP2011529073A5 (https=) | ||
| JP6285968B2 (ja) | （２ｓ，５ｒ）−６−ベンジルオキシ−７−オキソ−１，６−ジアザ−ビシクロ［３．２．１］オクタン−２−カルボン酸のナトリウム塩およびその調製 | |
| JP2004531563A5 (https=) | ||
| RU2015129560A (ru) | Производные маннозы для лечения бактериальных инфекций | |
| JP2017504576A5 (https=) | ||
| JP2009507909A5 (https=) | ||
| CY1114308T1 (el) | Παραγωγα της 3-αλκυλο-5-(4-αλκυλ-5-οξο-τετραϋδροφουραν-2-υλο)πυρρολιδιν-2-ονης ως ενδιαμεσες ενωσεις στη συνθεση των υποδοχεων της ρενινης | |
| RU2006118367A (ru) | Оксазольные производные тетрациклинов | |
| JP2004517070A5 (https=) | ||
| JP2011523952A5 (https=) | ||
| ES2539908T3 (es) | Métodos de preparación de un compuesto profármaco inhibidor de la fijación del VIH e intermedios | |
| JP2007502295A5 (https=) | ||
| AU2014284224A1 (en) | Free base crystals | |
| JP2008530106A5 (https=) | ||
| AR047739A1 (es) | Polimorfos cristalinos de un ligando receptor de cxc-quimiocina | |
| JP2008517897A5 (https=) | ||
| JP2011529942A5 (https=) | ||
| RU2011101661A (ru) | Пиримидилсульфонамидное производное и его применение для лечения хемокин-опосредованных заболеваний | |
| JP2005508954A5 (https=) | ||
| JP2015531746A5 (https=) |