JP2007512842A5 - - Google Patents
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- Publication number
- JP2007512842A5 JP2007512842A5 JP2006542692A JP2006542692A JP2007512842A5 JP 2007512842 A5 JP2007512842 A5 JP 2007512842A5 JP 2006542692 A JP2006542692 A JP 2006542692A JP 2006542692 A JP2006542692 A JP 2006542692A JP 2007512842 A5 JP2007512842 A5 JP 2007512842A5
- Authority
- JP
- Japan
- Prior art keywords
- cell
- construct
- virus
- peptide
- icosahedral
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 25
- 108090000765 processed proteins & peptides Proteins 0.000 claims 25
- 210000000234 capsid Anatomy 0.000 claims 14
- 150000007523 nucleic acids Chemical class 0.000 claims 13
- 241000700605 Viruses Species 0.000 claims 12
- 230000004927 fusion Effects 0.000 claims 8
- 108020004707 nucleic acids Proteins 0.000 claims 7
- 102000039446 nucleic acids Human genes 0.000 claims 7
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 6
- 239000002245 particle Substances 0.000 claims 6
- 241000589516 Pseudomonas Species 0.000 claims 5
- 239000000427 antigen Substances 0.000 claims 4
- 102000036639 antigens Human genes 0.000 claims 4
- 108091007433 antigens Proteins 0.000 claims 4
- 231100000331 toxic Toxicity 0.000 claims 3
- 230000002588 toxic effect Effects 0.000 claims 3
- 230000003612 virological effect Effects 0.000 claims 3
- 241000724328 Alfalfa mosaic virus Species 0.000 claims 2
- 108700042778 Antimicrobial Peptides Proteins 0.000 claims 2
- 102000044503 Antimicrobial Peptides Human genes 0.000 claims 2
- 241000724254 Cowpea chlorotic mottle virus Species 0.000 claims 2
- 241000723655 Cowpea mosaic virus Species 0.000 claims 2
- 241000196324 Embryophyta Species 0.000 claims 2
- 239000000178 monomer Substances 0.000 claims 2
- 239000003910 polypeptide antibiotic agent Substances 0.000 claims 2
- 241000701931 Canine parvovirus Species 0.000 claims 1
- 108091028732 Concatemer Proteins 0.000 claims 1
- 241000710945 Eastern equine encephalitis virus Species 0.000 claims 1
- 241000589540 Pseudomonas fluorescens Species 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 229960002235 anthrax antigen Drugs 0.000 claims 1
- 230000000813 microbial effect Effects 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
- 229960005486 vaccine Drugs 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US52598203P | 2003-12-01 | 2003-12-01 | |
| PCT/US2004/040117 WO2005067478A2 (en) | 2003-12-01 | 2004-12-01 | Recombinant icosahedral virus like particle production in pseudomonads |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007512842A JP2007512842A (ja) | 2007-05-24 |
| JP2007512842A5 true JP2007512842A5 (https=) | 2008-01-17 |
Family
ID=34794205
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006542692A Pending JP2007512842A (ja) | 2003-12-01 | 2004-12-01 | シュードモナスにおける組換え二十面体ウイルス様粒子の生産 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20050214321A1 (https=) |
| EP (1) | EP1758925A4 (https=) |
| JP (1) | JP2007512842A (https=) |
| KR (1) | KR20060114340A (https=) |
| CN (1) | CN101151272A (https=) |
| AU (1) | AU2004313458B2 (https=) |
| BR (1) | BRPI0417159A (https=) |
| CA (1) | CA2547511A1 (https=) |
| MX (1) | MXPA06006221A (https=) |
| WO (1) | WO2005067478A2 (https=) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9453251B2 (en) | 2002-10-08 | 2016-09-27 | Pfenex Inc. | Expression of mammalian proteins in Pseudomonas fluorescens |
| EP1758925A4 (en) * | 2003-12-01 | 2009-04-08 | Dow Global Technologies Inc | PRODUCTION OF A RECOMBINANT ICOSAHEDRIC VIRUS LIKE PARTICLE |
| WO2005086667A2 (en) * | 2004-02-27 | 2005-09-22 | The Dow Chemical Company | High efficiency peptide production in plant cells |
| US8603824B2 (en) | 2004-07-26 | 2013-12-10 | Pfenex, Inc. | Process for improved protein expression by strain engineering |
| WO2007053188A2 (en) * | 2005-06-01 | 2007-05-10 | Dow Global Technologies, Inc. | Production of multivalent virus like particles |
| EP1909829A4 (en) * | 2005-07-19 | 2009-11-11 | Dow Global Technologies Inc | RECOMBINANT GRIP VACCINES |
| WO2008027099A2 (en) * | 2006-05-30 | 2008-03-06 | Dow Global Technologies Inc. | Rpa optimization |
| AT503690A1 (de) * | 2006-06-09 | 2007-12-15 | Biomay Ag | Hypoallergene moleküle |
| US7998487B2 (en) * | 2007-02-16 | 2011-08-16 | The Salk Institute For Biological Studies | Antitoxin and vaccine platform based on nodavirus VLPs |
| US9580719B2 (en) | 2007-04-27 | 2017-02-28 | Pfenex, Inc. | Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins |
| JP5444553B2 (ja) | 2007-04-27 | 2014-03-19 | フェネックス インコーポレイテッド | 微生物宿主を迅速にスクリーニングして、異種タンパク質発現の収率および／または質が改善されている特定の株を同定する方法 |
| US9376470B2 (en) | 2008-11-28 | 2016-06-28 | Funpep Inc. | Polypeptide having angiogenesis-inducing activity and antibacterial activity, and use thereof for medical purposes |
| JP5750765B2 (ja) * | 2009-03-06 | 2015-07-22 | 株式会社ファンペップ | ポリペプチド及びその抗菌または消毒用途 |
| US8969311B2 (en) | 2009-05-25 | 2015-03-03 | Anges Mg, Inc. | Polypeptide having antibacterial activity and angiogenesis-inducing activity and wound-healing drug containing said polypeptide |
| CA2765357A1 (en) * | 2009-06-15 | 2010-12-23 | Plant Bioscience Limited | Production of viral capsids |
| NZ717682A (en) | 2012-02-16 | 2017-10-27 | Vlp Therapeutics Llc | Virus like particle composition |
| RU2525136C1 (ru) * | 2012-12-14 | 2014-08-10 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) | Способ получения препаративных количеств антигенов флоэмно-ограниченных вирусов |
| RU2555534C2 (ru) * | 2013-05-23 | 2015-07-10 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) | Способ получения препаративных количеств вирусных частиц флоэмно-органиченных вирусов |
| US9637532B2 (en) * | 2013-07-12 | 2017-05-02 | Vlp Therapeutics, Llc | Virus like particle comprising PD-1 antigen or PD-1 ligand antigen |
| CN103409377B (zh) * | 2013-08-28 | 2015-12-23 | 中国农业科学院兰州兽医研究所 | 犬细小病毒病毒样颗粒的制备及用途 |
| CN103882047B (zh) * | 2014-03-18 | 2016-06-29 | 杨霞 | 重组人酸性成纤维细胞生长因子蛋白的制备方法 |
| JP6824154B2 (ja) | 2014-08-08 | 2021-02-03 | ブイエルピー・セラピューティクス・リミテッド・ライアビリティ・カンパニーＶＬＰ Ｔｈｅｒａｐｅｕｔｉｃｓ， ＬＬＣ | 修飾エンベロープタンパク質ｅ３を含むウイルス様粒子 |
| US10385101B2 (en) | 2014-08-08 | 2019-08-20 | Vlp Therapeutics, Llc | Virus like particle comprising modified envelope protein E3 |
| KR102532832B1 (ko) | 2014-09-11 | 2023-05-16 | 브이엘피 테라퓨틱스 인코포레이티드 | 플라비바이러스 바이러스 유사 입자 |
| US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
| SG11202005792RA (en) | 2017-12-20 | 2020-07-29 | Vlp Therapeutics Llc | Alphavirus replicon particle |
| US12280102B2 (en) | 2020-04-17 | 2025-04-22 | Vlp Therapeutics, Inc. | Alphavirus replicon encoding chimeric SARS-CoV-2 receptor binding domains |
| JP2023524055A (ja) | 2020-04-30 | 2023-06-08 | ブイエルピー・セラピューティクス・インコーポレイテッド | サイトカイン免疫療法 |
| CN113278622B (zh) * | 2021-06-09 | 2023-09-19 | 集美大学 | 一种变形假单胞菌适配体及其筛选方法 |
| WO2024006433A1 (en) * | 2022-06-30 | 2024-01-04 | Carnegie Mellon University | Method for production of virus-like particles for gene delivery |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4595658A (en) * | 1982-09-13 | 1986-06-17 | The Rockefeller University | Method for facilitating externalization of proteins synthesized in bacteria |
| US4511503A (en) * | 1982-12-22 | 1985-04-16 | Genentech, Inc. | Purification and activity assurance of precipitated heterologous proteins |
| US4755465A (en) * | 1983-04-25 | 1988-07-05 | Genentech, Inc. | Secretion of correctly processed human growth hormone in E. coli and Pseudomonas |
| US4680264A (en) * | 1983-07-01 | 1987-07-14 | Lubrizol Genetics, Inc. | Class II mobilizable gram-negative plasmid |
| US5281532A (en) * | 1983-07-27 | 1994-01-25 | Mycogen Corporation | Pseudomas hosts transformed with bacillus endotoxin genes |
| US4637980A (en) * | 1983-08-09 | 1987-01-20 | Smithkline Beckman Corporation | Externalization of products of bacteria |
| US4695455A (en) * | 1985-01-22 | 1987-09-22 | Mycogen Corporation | Cellular encapsulation of pesticides produced by expression of heterologous genes |
| US4695462A (en) * | 1985-06-28 | 1987-09-22 | Mycogen Corporation | Cellular encapsulation of biological pesticides |
| US5232840A (en) * | 1986-03-27 | 1993-08-03 | Monsanto Company | Enhanced protein production in bacteria by employing a novel ribosome binding site |
| US5128130A (en) * | 1988-01-22 | 1992-07-07 | Mycogen Corporation | Hybrid Bacillus thuringiensis gene, plasmid and transformed Pseudomonas fluorescens |
| US6054566A (en) * | 1988-02-26 | 2000-04-25 | Biosource Technologies, Inc. | Recombinant animal viral nucleic acids |
| US5316931A (en) * | 1988-02-26 | 1994-05-31 | Biosource Genetics Corp. | Plant viral vectors having heterologous subgenomic promoters for systemic expression of foreign genes |
| US5055294A (en) * | 1988-03-03 | 1991-10-08 | Mycogen Corporation | Chimeric bacillus thuringiensis crystal protein gene comprising hd-73 and berliner 1715 toxin genes, transformed and expressed in pseudomonas fluorescens |
| US5169772A (en) * | 1988-06-06 | 1992-12-08 | Massachusetts Institute Of Technology | Large scale method for purification of high purity heparinase from flavobacterium heparinum |
| US6780613B1 (en) * | 1988-10-28 | 2004-08-24 | Genentech, Inc. | Growth hormone variants |
| US5169760A (en) * | 1989-07-27 | 1992-12-08 | Mycogen Corporation | Method, vectors, and host cells for the control of expression of heterologous genes from lac operated promoters |
| GB9108386D0 (en) * | 1991-04-19 | 1991-06-05 | Agricultural Genetics Co | Modified plant viruses as vectors |
| US5527883A (en) * | 1994-05-06 | 1996-06-18 | Mycogen Corporation | Delta-endotoxin expression in pseudomonas fluorescens |
| AU702802B2 (en) * | 1994-10-18 | 1999-03-04 | Scottish Crop Research Institute | Method of producing a chimeric protein |
| US5869287A (en) * | 1996-07-12 | 1999-02-09 | Wisconsin Alumni Research Foundation | Method of producing particles containing nucleic acid sequences in yeast |
| KR100312456B1 (ko) * | 1999-03-13 | 2001-11-03 | 윤덕용 | 슈도모나스 플루오레슨스 유래의 외래단백질 분비촉진유전자 |
| US6514948B1 (en) * | 1999-07-02 | 2003-02-04 | The Regents Of The University Of California | Method for enhancing an immune response |
| AU2002339224B2 (en) * | 2001-09-14 | 2008-10-09 | Kuros Us Llc | Packaging of immunostimulatory substances into virus-like particles: method of preparation and use |
| ATE443767T1 (de) * | 2002-04-22 | 2009-10-15 | Dow Global Technologies Inc | Kostengünstige herstellung von peptiden |
| WO2003103605A2 (en) * | 2002-06-07 | 2003-12-18 | Large Scale Biology Corporation | Flexible vaccine assembly and vaccine delivery platform |
| EP1758925A4 (en) * | 2003-12-01 | 2009-04-08 | Dow Global Technologies Inc | PRODUCTION OF A RECOMBINANT ICOSAHEDRIC VIRUS LIKE PARTICLE |
-
2004
- 2004-12-01 EP EP04821151A patent/EP1758925A4/en not_active Withdrawn
- 2004-12-01 KR KR1020067010713A patent/KR20060114340A/ko not_active Ceased
- 2004-12-01 JP JP2006542692A patent/JP2007512842A/ja active Pending
- 2004-12-01 MX MXPA06006221A patent/MXPA06006221A/es unknown
- 2004-12-01 WO PCT/US2004/040117 patent/WO2005067478A2/en not_active Ceased
- 2004-12-01 AU AU2004313458A patent/AU2004313458B2/en not_active Expired - Fee Related
- 2004-12-01 US US11/001,626 patent/US20050214321A1/en not_active Abandoned
- 2004-12-01 BR BRPI0417159-4A patent/BRPI0417159A/pt not_active IP Right Cessation
- 2004-12-01 CN CNA2004800410956A patent/CN101151272A/zh active Pending
- 2004-12-01 CA CA002547511A patent/CA2547511A1/en not_active Abandoned
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