CN101151272A - 在假单胞菌中生产重组二十面体病毒样颗粒 - Google Patents

在假单胞菌中生产重组二十面体病毒样颗粒 Download PDF

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Publication number
CN101151272A
CN101151272A CNA2004800410956A CN200480041095A CN101151272A CN 101151272 A CN101151272 A CN 101151272A CN A2004800410956 A CNA2004800410956 A CN A2004800410956A CN 200480041095 A CN200480041095 A CN 200480041095A CN 101151272 A CN101151272 A CN 101151272A
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peptide
cell
capsid
virus
recombinant
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L·拉索霍娃
P·P·达奥
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Dow Global Technologies LLC
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Dow Global Technologies LLC
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    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
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    • C12N15/02—Preparation of hybrid cells by fusion of two or more cells, e.g. protoplast fusion
    • C12N15/03—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
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    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5256—Virus expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5258—Virus-like particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
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    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
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    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14311—Parvovirus, e.g. minute virus of mice
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    • C12N2770/00011—Details
    • C12N2770/36011—Togaviridae
    • C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
    • C12N2770/36122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

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  • Biotechnology (AREA)
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  • Microbiology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
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  • Animal Behavior & Ethology (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CNA2004800410956A 2003-12-01 2004-12-01 在假单胞菌中生产重组二十面体病毒样颗粒 Pending CN101151272A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52598203P 2003-12-01 2003-12-01
US60/525,982 2003-12-01

Publications (1)

Publication Number Publication Date
CN101151272A true CN101151272A (zh) 2008-03-26

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CNA2004800410956A Pending CN101151272A (zh) 2003-12-01 2004-12-01 在假单胞菌中生产重组二十面体病毒样颗粒

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Country Link
US (1) US20050214321A1 (https=)
EP (1) EP1758925A4 (https=)
JP (1) JP2007512842A (https=)
KR (1) KR20060114340A (https=)
CN (1) CN101151272A (https=)
AU (1) AU2004313458B2 (https=)
BR (1) BRPI0417159A (https=)
CA (1) CA2547511A1 (https=)
MX (1) MXPA06006221A (https=)
WO (1) WO2005067478A2 (https=)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103409377A (zh) * 2013-08-28 2013-11-27 中国农业科学院兰州兽医研究所 犬细小病毒病毒样颗粒的制备及用途
CN103882047A (zh) * 2014-03-18 2014-06-25 太原锦波生物医药科技有限公司 重组人酸性成纤维细胞生长因子蛋白的制备方法
CN105358683A (zh) * 2013-07-12 2016-02-24 Vlp治疗有限责任公司 包含pd-1抗原或pd-1配体抗原的病毒样颗粒
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria

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EP1758925A4 (en) * 2003-12-01 2009-04-08 Dow Global Technologies Inc PRODUCTION OF A RECOMBINANT ICOSAHEDRIC VIRUS LIKE PARTICLE
WO2005086667A2 (en) * 2004-02-27 2005-09-22 The Dow Chemical Company High efficiency peptide production in plant cells
US8603824B2 (en) 2004-07-26 2013-12-10 Pfenex, Inc. Process for improved protein expression by strain engineering
WO2007053188A2 (en) * 2005-06-01 2007-05-10 Dow Global Technologies, Inc. Production of multivalent virus like particles
EP1909829A4 (en) * 2005-07-19 2009-11-11 Dow Global Technologies Inc RECOMBINANT GRIP VACCINES
WO2008027099A2 (en) * 2006-05-30 2008-03-06 Dow Global Technologies Inc. Rpa optimization
AT503690A1 (de) * 2006-06-09 2007-12-15 Biomay Ag Hypoallergene moleküle
US7998487B2 (en) * 2007-02-16 2011-08-16 The Salk Institute For Biological Studies Antitoxin and vaccine platform based on nodavirus VLPs
US9580719B2 (en) 2007-04-27 2017-02-28 Pfenex, Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
JP5444553B2 (ja) 2007-04-27 2014-03-19 フェネックス インコーポレイテッド 微生物宿主を迅速にスクリーニングして、異種タンパク質発現の収率および／または質が改善されている特定の株を同定する方法
US9376470B2 (en) 2008-11-28 2016-06-28 Funpep Inc. Polypeptide having angiogenesis-inducing activity and antibacterial activity, and use thereof for medical purposes
JP5750765B2 (ja) * 2009-03-06 2015-07-22 株式会社ファンペップ ポリペプチド及びその抗菌または消毒用途
US8969311B2 (en) 2009-05-25 2015-03-03 Anges Mg, Inc. Polypeptide having antibacterial activity and angiogenesis-inducing activity and wound-healing drug containing said polypeptide
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RU2525136C1 (ru) * 2012-12-14 2014-08-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) Способ получения препаративных количеств антигенов флоэмно-ограниченных вирусов
RU2555534C2 (ru) * 2013-05-23 2015-07-10 Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) Способ получения препаративных количеств вирусных частиц флоэмно-органиченных вирусов
JP6824154B2 (ja) 2014-08-08 2021-02-03 ブイエルピー・セラピューティクス・リミテッド・ライアビリティ・カンパニーＶＬＰ Ｔｈｅｒａｐｅｕｔｉｃｓ， ＬＬＣ 修飾エンベロープタンパク質ｅ３を含むウイルス様粒子
US10385101B2 (en) 2014-08-08 2019-08-20 Vlp Therapeutics, Llc Virus like particle comprising modified envelope protein E3
KR102532832B1 (ko) 2014-09-11 2023-05-16 브이엘피 테라퓨틱스 인코포레이티드 플라비바이러스 바이러스 유사 입자
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US12280102B2 (en) 2020-04-17 2025-04-22 Vlp Therapeutics, Inc. Alphavirus replicon encoding chimeric SARS-CoV-2 receptor binding domains
JP2023524055A (ja) 2020-04-30 2023-06-08 ブイエルピー・セラピューティクス・インコーポレイテッド サイトカイン免疫療法
CN113278622B (zh) * 2021-06-09 2023-09-19 集美大学 一种变形假单胞菌适配体及其筛选方法
WO2024006433A1 (en) * 2022-06-30 2024-01-04 Carnegie Mellon University Method for production of virus-like particles for gene delivery

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105358683A (zh) * 2013-07-12 2016-02-24 Vlp治疗有限责任公司 包含pd-1抗原或pd-1配体抗原的病毒样颗粒
TWI676636B (zh) * 2013-07-12 2019-11-11 Ｖｌｐ醫療股份有限公司 包含ｐｄ－１抗原或ｐｄ－１配體抗原的類病毒粒子
CN103409377A (zh) * 2013-08-28 2013-11-27 中国农业科学院兰州兽医研究所 犬细小病毒病毒样颗粒的制备及用途
CN103409377B (zh) * 2013-08-28 2015-12-23 中国农业科学院兰州兽医研究所 犬细小病毒病毒样颗粒的制备及用途
CN103882047A (zh) * 2014-03-18 2014-06-25 太原锦波生物医药科技有限公司 重组人酸性成纤维细胞生长因子蛋白的制备方法
CN103882047B (zh) * 2014-03-18 2016-06-29 杨霞 重组人酸性成纤维细胞生长因子蛋白的制备方法
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria

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AU2004313458A1 (en) 2005-07-28
JP2007512842A (ja) 2007-05-24
EP1758925A4 (en) 2009-04-08
EP1758925A2 (en) 2007-03-07
MXPA06006221A (es) 2008-02-13
CA2547511A1 (en) 2005-07-28
US20050214321A1 (en) 2005-09-29
WO2005067478A3 (en) 2007-11-22
AU2004313458B2 (en) 2010-07-22
BRPI0417159A (pt) 2007-03-06
WO2005067478A2 (en) 2005-07-28
KR20060114340A (ko) 2006-11-06

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