CA2547511A1 - Recombinant icosahedral virus like particle production in pseudomonads - Google Patents
Recombinant icosahedral virus like particle production in pseudomonads Download PDFInfo
- Publication number
- CA2547511A1 CA2547511A1 CA002547511A CA2547511A CA2547511A1 CA 2547511 A1 CA2547511 A1 CA 2547511A1 CA 002547511 A CA002547511 A CA 002547511A CA 2547511 A CA2547511 A CA 2547511A CA 2547511 A1 CA2547511 A1 CA 2547511A1
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- Prior art keywords
- peptide
- cell
- virus
- icosahedral
- recombinant
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- C—CHEMISTRY; METALLURGY
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- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C—CHEMISTRY; METALLURGY
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5258—Virus-like particles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14311—Parvovirus, e.g. minute virus of mice
- C12N2750/14322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/14011—Bromoviridae
- C12N2770/14023—Virus like particles [VLP]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/36011—Togaviridae
- C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
- C12N2770/36122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Cell Biology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US52598203P | 2003-12-01 | 2003-12-01 | |
| US60/525,982 | 2003-12-01 | ||
| PCT/US2004/040117 WO2005067478A2 (en) | 2003-12-01 | 2004-12-01 | Recombinant icosahedral virus like particle production in pseudomonads |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2547511A1 true CA2547511A1 (en) | 2005-07-28 |
Family
ID=34794205
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002547511A Abandoned CA2547511A1 (en) | 2003-12-01 | 2004-12-01 | Recombinant icosahedral virus like particle production in pseudomonads |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20050214321A1 (https=) |
| EP (1) | EP1758925A4 (https=) |
| JP (1) | JP2007512842A (https=) |
| KR (1) | KR20060114340A (https=) |
| CN (1) | CN101151272A (https=) |
| AU (1) | AU2004313458B2 (https=) |
| BR (1) | BRPI0417159A (https=) |
| CA (1) | CA2547511A1 (https=) |
| MX (1) | MXPA06006221A (https=) |
| WO (1) | WO2005067478A2 (https=) |
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| US9453251B2 (en) | 2002-10-08 | 2016-09-27 | Pfenex Inc. | Expression of mammalian proteins in Pseudomonas fluorescens |
| EP1758925A4 (en) * | 2003-12-01 | 2009-04-08 | Dow Global Technologies Inc | PRODUCTION OF A RECOMBINANT ICOSAHEDRIC VIRUS LIKE PARTICLE |
| WO2005086667A2 (en) * | 2004-02-27 | 2005-09-22 | The Dow Chemical Company | High efficiency peptide production in plant cells |
| US8603824B2 (en) | 2004-07-26 | 2013-12-10 | Pfenex, Inc. | Process for improved protein expression by strain engineering |
| WO2007053188A2 (en) * | 2005-06-01 | 2007-05-10 | Dow Global Technologies, Inc. | Production of multivalent virus like particles |
| EP1909829A4 (en) * | 2005-07-19 | 2009-11-11 | Dow Global Technologies Inc | RECOMBINANT GRIP VACCINES |
| WO2008027099A2 (en) * | 2006-05-30 | 2008-03-06 | Dow Global Technologies Inc. | Rpa optimization |
| AT503690A1 (de) * | 2006-06-09 | 2007-12-15 | Biomay Ag | Hypoallergene moleküle |
| US7998487B2 (en) * | 2007-02-16 | 2011-08-16 | The Salk Institute For Biological Studies | Antitoxin and vaccine platform based on nodavirus VLPs |
| US9580719B2 (en) | 2007-04-27 | 2017-02-28 | Pfenex, Inc. | Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins |
| JP5444553B2 (ja) | 2007-04-27 | 2014-03-19 | フェネックス インコーポレイテッド | 微生物宿主を迅速にスクリーニングして、異種タンパク質発現の収率および/または質が改善されている特定の株を同定する方法 |
| US9376470B2 (en) | 2008-11-28 | 2016-06-28 | Funpep Inc. | Polypeptide having angiogenesis-inducing activity and antibacterial activity, and use thereof for medical purposes |
| JP5750765B2 (ja) * | 2009-03-06 | 2015-07-22 | 株式会社ファンペップ | ポリペプチド及びその抗菌または消毒用途 |
| US8969311B2 (en) | 2009-05-25 | 2015-03-03 | Anges Mg, Inc. | Polypeptide having antibacterial activity and angiogenesis-inducing activity and wound-healing drug containing said polypeptide |
| CA2765357A1 (en) * | 2009-06-15 | 2010-12-23 | Plant Bioscience Limited | Production of viral capsids |
| NZ717682A (en) | 2012-02-16 | 2017-10-27 | Vlp Therapeutics Llc | Virus like particle composition |
| RU2525136C1 (ru) * | 2012-12-14 | 2014-08-10 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) | Способ получения препаративных количеств антигенов флоэмно-ограниченных вирусов |
| RU2555534C2 (ru) * | 2013-05-23 | 2015-07-10 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) | Способ получения препаративных количеств вирусных частиц флоэмно-органиченных вирусов |
| US9637532B2 (en) * | 2013-07-12 | 2017-05-02 | Vlp Therapeutics, Llc | Virus like particle comprising PD-1 antigen or PD-1 ligand antigen |
| CN103409377B (zh) * | 2013-08-28 | 2015-12-23 | 中国农业科学院兰州兽医研究所 | 犬细小病毒病毒样颗粒的制备及用途 |
| CN103882047B (zh) * | 2014-03-18 | 2016-06-29 | 杨霞 | 重组人酸性成纤维细胞生长因子蛋白的制备方法 |
| JP6824154B2 (ja) | 2014-08-08 | 2021-02-03 | ブイエルピー・セラピューティクス・リミテッド・ライアビリティ・カンパニーVLP Therapeutics, LLC | 修飾エンベロープタンパク質e3を含むウイルス様粒子 |
| US10385101B2 (en) | 2014-08-08 | 2019-08-20 | Vlp Therapeutics, Llc | Virus like particle comprising modified envelope protein E3 |
| KR102532832B1 (ko) | 2014-09-11 | 2023-05-16 | 브이엘피 테라퓨틱스 인코포레이티드 | 플라비바이러스 바이러스 유사 입자 |
| US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
| SG11202005792RA (en) | 2017-12-20 | 2020-07-29 | Vlp Therapeutics Llc | Alphavirus replicon particle |
| US12280102B2 (en) | 2020-04-17 | 2025-04-22 | Vlp Therapeutics, Inc. | Alphavirus replicon encoding chimeric SARS-CoV-2 receptor binding domains |
| JP2023524055A (ja) | 2020-04-30 | 2023-06-08 | ブイエルピー・セラピューティクス・インコーポレイテッド | サイトカイン免疫療法 |
| CN113278622B (zh) * | 2021-06-09 | 2023-09-19 | 集美大学 | 一种变形假单胞菌适配体及其筛选方法 |
| WO2024006433A1 (en) * | 2022-06-30 | 2024-01-04 | Carnegie Mellon University | Method for production of virus-like particles for gene delivery |
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| US4595658A (en) * | 1982-09-13 | 1986-06-17 | The Rockefeller University | Method for facilitating externalization of proteins synthesized in bacteria |
| US4511503A (en) * | 1982-12-22 | 1985-04-16 | Genentech, Inc. | Purification and activity assurance of precipitated heterologous proteins |
| US4755465A (en) * | 1983-04-25 | 1988-07-05 | Genentech, Inc. | Secretion of correctly processed human growth hormone in E. coli and Pseudomonas |
| US4680264A (en) * | 1983-07-01 | 1987-07-14 | Lubrizol Genetics, Inc. | Class II mobilizable gram-negative plasmid |
| US5281532A (en) * | 1983-07-27 | 1994-01-25 | Mycogen Corporation | Pseudomas hosts transformed with bacillus endotoxin genes |
| US4637980A (en) * | 1983-08-09 | 1987-01-20 | Smithkline Beckman Corporation | Externalization of products of bacteria |
| US4695455A (en) * | 1985-01-22 | 1987-09-22 | Mycogen Corporation | Cellular encapsulation of pesticides produced by expression of heterologous genes |
| US4695462A (en) * | 1985-06-28 | 1987-09-22 | Mycogen Corporation | Cellular encapsulation of biological pesticides |
| US5232840A (en) * | 1986-03-27 | 1993-08-03 | Monsanto Company | Enhanced protein production in bacteria by employing a novel ribosome binding site |
| US5128130A (en) * | 1988-01-22 | 1992-07-07 | Mycogen Corporation | Hybrid Bacillus thuringiensis gene, plasmid and transformed Pseudomonas fluorescens |
| US6054566A (en) * | 1988-02-26 | 2000-04-25 | Biosource Technologies, Inc. | Recombinant animal viral nucleic acids |
| US5316931A (en) * | 1988-02-26 | 1994-05-31 | Biosource Genetics Corp. | Plant viral vectors having heterologous subgenomic promoters for systemic expression of foreign genes |
| US5055294A (en) * | 1988-03-03 | 1991-10-08 | Mycogen Corporation | Chimeric bacillus thuringiensis crystal protein gene comprising hd-73 and berliner 1715 toxin genes, transformed and expressed in pseudomonas fluorescens |
| US5169772A (en) * | 1988-06-06 | 1992-12-08 | Massachusetts Institute Of Technology | Large scale method for purification of high purity heparinase from flavobacterium heparinum |
| US6780613B1 (en) * | 1988-10-28 | 2004-08-24 | Genentech, Inc. | Growth hormone variants |
| US5169760A (en) * | 1989-07-27 | 1992-12-08 | Mycogen Corporation | Method, vectors, and host cells for the control of expression of heterologous genes from lac operated promoters |
| GB9108386D0 (en) * | 1991-04-19 | 1991-06-05 | Agricultural Genetics Co | Modified plant viruses as vectors |
| US5527883A (en) * | 1994-05-06 | 1996-06-18 | Mycogen Corporation | Delta-endotoxin expression in pseudomonas fluorescens |
| AU702802B2 (en) * | 1994-10-18 | 1999-03-04 | Scottish Crop Research Institute | Method of producing a chimeric protein |
| US5869287A (en) * | 1996-07-12 | 1999-02-09 | Wisconsin Alumni Research Foundation | Method of producing particles containing nucleic acid sequences in yeast |
| KR100312456B1 (ko) * | 1999-03-13 | 2001-11-03 | 윤덕용 | 슈도모나스 플루오레슨스 유래의 외래단백질 분비촉진유전자 |
| US6514948B1 (en) * | 1999-07-02 | 2003-02-04 | The Regents Of The University Of California | Method for enhancing an immune response |
| AU2002339224B2 (en) * | 2001-09-14 | 2008-10-09 | Kuros Us Llc | Packaging of immunostimulatory substances into virus-like particles: method of preparation and use |
| ATE443767T1 (de) * | 2002-04-22 | 2009-10-15 | Dow Global Technologies Inc | Kostengünstige herstellung von peptiden |
| WO2003103605A2 (en) * | 2002-06-07 | 2003-12-18 | Large Scale Biology Corporation | Flexible vaccine assembly and vaccine delivery platform |
| EP1758925A4 (en) * | 2003-12-01 | 2009-04-08 | Dow Global Technologies Inc | PRODUCTION OF A RECOMBINANT ICOSAHEDRIC VIRUS LIKE PARTICLE |
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2004
- 2004-12-01 EP EP04821151A patent/EP1758925A4/en not_active Withdrawn
- 2004-12-01 KR KR1020067010713A patent/KR20060114340A/ko not_active Ceased
- 2004-12-01 JP JP2006542692A patent/JP2007512842A/ja active Pending
- 2004-12-01 MX MXPA06006221A patent/MXPA06006221A/es unknown
- 2004-12-01 WO PCT/US2004/040117 patent/WO2005067478A2/en not_active Ceased
- 2004-12-01 AU AU2004313458A patent/AU2004313458B2/en not_active Expired - Fee Related
- 2004-12-01 US US11/001,626 patent/US20050214321A1/en not_active Abandoned
- 2004-12-01 BR BRPI0417159-4A patent/BRPI0417159A/pt not_active IP Right Cessation
- 2004-12-01 CN CNA2004800410956A patent/CN101151272A/zh active Pending
- 2004-12-01 CA CA002547511A patent/CA2547511A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2004313458A1 (en) | 2005-07-28 |
| CN101151272A (zh) | 2008-03-26 |
| JP2007512842A (ja) | 2007-05-24 |
| EP1758925A4 (en) | 2009-04-08 |
| EP1758925A2 (en) | 2007-03-07 |
| MXPA06006221A (es) | 2008-02-13 |
| US20050214321A1 (en) | 2005-09-29 |
| WO2005067478A3 (en) | 2007-11-22 |
| AU2004313458B2 (en) | 2010-07-22 |
| BRPI0417159A (pt) | 2007-03-06 |
| WO2005067478A2 (en) | 2005-07-28 |
| KR20060114340A (ko) | 2006-11-06 |
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