JP2007511215A5 - - Google Patents
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- Publication number
- JP2007511215A5 JP2007511215A5 JP2006538966A JP2006538966A JP2007511215A5 JP 2007511215 A5 JP2007511215 A5 JP 2007511215A5 JP 2006538966 A JP2006538966 A JP 2006538966A JP 2006538966 A JP2006538966 A JP 2006538966A JP 2007511215 A5 JP2007511215 A5 JP 2007511215A5
- Authority
- JP
- Japan
- Prior art keywords
- herpes simplex
- simplex virus
- nucleic acid
- genome
- virus according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0326798.6A GB0326798D0 (en) | 2003-11-17 | 2003-11-17 | Methods for generating mutant virus |
| PCT/GB2004/004851 WO2005049845A2 (en) | 2003-11-17 | 2004-11-17 | Oncolytic herpes simplex virus encoding a heterologous nitroreductase |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007511215A JP2007511215A (ja) | 2007-05-10 |
| JP2007511215A5 true JP2007511215A5 (https=) | 2008-01-10 |
Family
ID=29763982
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006538966A Pending JP2007511215A (ja) | 2003-11-17 | 2004-11-17 | ウイルス変異株 |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US7498161B2 (https=) |
| EP (3) | EP1685254B1 (https=) |
| JP (1) | JP2007511215A (https=) |
| AT (2) | ATE433493T1 (https=) |
| DE (2) | DE602004029608D1 (https=) |
| GB (1) | GB0326798D0 (https=) |
| WO (2) | WO2005049844A2 (https=) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9415320D0 (en) | 1994-07-29 | 1994-09-21 | Medical Res Council | Cancer treatment |
| WO2007026146A1 (en) * | 2005-08-30 | 2007-03-08 | Crusade Laboratories Limited | Treatment using herpes simplex virus |
| US7897146B2 (en) | 2003-11-17 | 2011-03-01 | Crusade Laboratories Limited | Treatment using herpes simplex virus |
| US20070003520A1 (en) | 2003-11-17 | 2007-01-04 | Brown Susanne M | Mutant viruses |
| GB0409596D0 (en) * | 2004-04-29 | 2004-06-02 | Crusade Lab Ltd | Novel herpes simplex viruses and uses thereof |
| GB2446721B (en) | 2007-02-16 | 2009-03-25 | Crusade Lab Ltd | Herpes simplex viruses and methods of viral replication |
| US20090081639A1 (en) * | 2007-05-31 | 2009-03-26 | Phil Hill | Assay for sensitivity to chemotherapeutic agents |
| GB0714578D0 (en) * | 2007-07-26 | 2007-09-05 | Crusade Lab Ltd | Viruses |
| US8334097B2 (en) * | 2009-05-01 | 2012-12-18 | Vivebio, Llc | Method of pooling and/or concentrating biological specimens for analysis |
| WO2011119925A2 (en) * | 2010-03-25 | 2011-09-29 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Synthetic herpes simplex viruses for treatment of cancers |
| EP2593796A4 (en) * | 2010-07-16 | 2016-07-27 | Auckland Uniservices Ltd | BACTERIAL NITROREDUCTASE ENZYMES AND METHOD THEREFOR |
| WO2012071276A1 (en) * | 2010-11-23 | 2012-05-31 | Xiaoliu Zhang | Oncolytic virus as an inducer for innate antitumor immunity |
| US9447156B2 (en) | 2011-05-17 | 2016-09-20 | St. Jude Children's Research Hospital | Methods and compositions for inhibiting neddylation of proteins |
| WO2013052915A2 (en) | 2011-10-05 | 2013-04-11 | Genelux Corporation | Method for detecting replication or colonization of a biological therapeutic |
| US20140087362A1 (en) | 2012-03-16 | 2014-03-27 | Aladar A. Szalay | Methods for assessing effectiveness and monitoring oncolytic virus treatment |
| WO2013158265A1 (en) | 2012-04-20 | 2013-10-24 | Genelux Corporation | Imaging methods for oncolytic virus therapy |
| EP2662117A1 (en) | 2012-05-11 | 2013-11-13 | Virttu Biologics Limited | Herpes Simplex Virus for the treatment of liver cancer |
| US20140140959A1 (en) | 2012-10-05 | 2014-05-22 | Aladar A. Szalay | Energy Absorbing-Based Diagnostic and Therapeutic Methods Employing Nucleic Acid Molecules Encoding Chromophore-Producing Enzymes |
| US10238700B2 (en) | 2014-01-02 | 2019-03-26 | Genelux Corporation | Oncolytic virus adjunct therapy with agents that increase virus infectivity |
| BR112017007765B1 (pt) | 2014-10-14 | 2023-10-03 | Halozyme, Inc | Composições de adenosina deaminase-2 (ada2), variantes do mesmo e métodos de usar o mesmo |
| WO2017181152A2 (en) | 2016-04-15 | 2017-10-19 | Alpine Immune Sciences, Inc. | Cd80 variant immunomodulatory proteins and uses thereof |
| MX2018012472A (es) | 2016-04-15 | 2019-08-12 | Alpine Immune Sciences Inc | Proteinas inmunomoduladoras variantes de ligando icos y sus usos. |
| WO2018022946A1 (en) | 2016-07-28 | 2018-02-01 | Alpine Immune Sciences, Inc. | Cd155 variant immunomodulatory proteins and uses thereof |
| US11471488B2 (en) | 2016-07-28 | 2022-10-18 | Alpine Immune Sciences, Inc. | CD155 variant immunomodulatory proteins and uses thereof |
| WO2018022945A1 (en) | 2016-07-28 | 2018-02-01 | Alpine Immune Sciences, Inc. | Cd112 variant immunomodulatory proteins and uses thereof |
| WO2018075978A1 (en) | 2016-10-20 | 2018-04-26 | Alpine Immune Sciences, Inc. | Secretable variant immunomodulatory proteins and engineered cell therapy |
| CN110869052A (zh) | 2016-12-23 | 2020-03-06 | 维图生物制剂公司 | 癌症的治疗 |
| CN110546265A (zh) | 2017-02-09 | 2019-12-06 | 因达普塔治疗公司 | 工程化自然杀伤(nk)细胞及其组合物和方法 |
| SG11201907769XA (en) | 2017-03-16 | 2019-09-27 | Alpine Immune Sciences Inc | Cd80 variant immunomodulatory proteins and uses thereof |
| EP3596116B1 (en) | 2017-03-16 | 2023-09-06 | Alpine Immune Sciences, Inc. | Pd-l1 variant immunomodulatory proteins and uses thereof |
| KR20190141146A (ko) | 2017-03-16 | 2019-12-23 | 알파인 이뮨 사이언시즈, 인코포레이티드 | Pd-l2 변이체 면역조절 단백질 및 그의 용도 |
| BR112020007542A2 (pt) | 2017-10-18 | 2020-12-01 | Alpine Immune Sciences, Inc. | proteínas imunomoduladoras ligantes de icos variantes e composições e métodos relacionados |
| AU2019205273B2 (en) | 2018-01-03 | 2024-04-04 | Alpine Immune Sciences, Inc. | Multi-domain immunomodulatory proteins and methods of use thereof |
| CN110117577B (zh) * | 2018-02-05 | 2023-10-24 | 中国科学院武汉物理与数学研究所 | 低毒单纯疱疹病毒系统及其构建方法和应用 |
| IL278294B2 (en) | 2018-05-01 | 2025-01-01 | Albert Einstein College Medicine | HSV-2-DELTA-gD vaccines and methods for their production and use |
| US11505782B2 (en) | 2018-06-04 | 2022-11-22 | Calidi Biotherapeutics, Inc. | Cell-based vehicles for potentiation of viral therapy |
| EA202000353A1 (ru) | 2018-06-04 | 2022-01-14 | Калиди Биотерапьютикс, Инк. | Основанные на клетках носители для потенциализации вирусной терапии |
| WO2019241758A1 (en) | 2018-06-15 | 2019-12-19 | Alpine Immune Sciences, Inc. | Pd-1 variant immunomodulatory proteins and uses thereof |
| US11242528B2 (en) | 2018-08-28 | 2022-02-08 | Actym Therapeutics, Inc. | Engineered immunostimulatory bacterial strains and uses thereof |
| CA3116192C (en) | 2018-11-06 | 2025-09-23 | Calidi Biotherapeutics (Nevada), Inc. | IMPROVED SYSTEMS FOR CELL-MEDIATED ONCOLYTIC VIRAL THERAPY |
| EP3884041A2 (en) | 2018-11-21 | 2021-09-29 | Indapta Therapeutics, Inc. | Methods for expansion of natural killer (nk) cell subset and related compositions and methods |
| TW202038947A (zh) | 2018-11-28 | 2020-11-01 | 德商創新分子有限責任公司 | 在與溶瘤病毒之組合療法中治療癌症的解旋酶引子酶抑制劑 |
| CA3120868A1 (en) | 2018-11-30 | 2020-06-04 | Alpine Immune Sciences, Inc. | Cd86 variant immunomodulatory proteins and uses thereof |
| US12024709B2 (en) | 2019-02-27 | 2024-07-02 | Actym Therapeutics, Inc. | Immunostimulatory bacteria engineered to colonize tumors, tumor-resident immune cells, and the tumor microenvironment |
| JP2022524951A (ja) | 2019-02-27 | 2022-05-11 | アクティム・セラピューティクス・インコーポレイテッド | 腫瘍、腫瘍常在免疫細胞および腫瘍微小環境にコロニー形成するよう操作した免疫刺激性細菌 |
| AU2021258194A1 (en) | 2020-04-22 | 2022-11-24 | Indapta Therapeutics, Inc. | Natural killer (NK) cell compositions and methods for generating same |
| WO2022147480A1 (en) | 2020-12-30 | 2022-07-07 | Ansun Biopharma, Inc. | Oncolytic virus encoding sialidase and multispecific immune cell engager |
| LT7046B (lt) | 2022-04-15 | 2024-02-12 | Vilniaus Universitetas | Hidrolazės ir jų panaudojimas |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5965138A (en) | 1985-09-06 | 1999-10-12 | Syntro Corporation | Recombinant chimeric virus and uses thereof |
| JP2538367B2 (ja) | 1988-06-24 | 1996-09-25 | ブリティッシュ・テクノロジー・グループ・リミテッド | Ｆｏｗｌｐｏｘウィルスの非必須領域 |
| GB9102126D0 (en) | 1991-01-31 | 1991-03-13 | Smithkline Beecham Biolog | Novel vaccine |
| DK0538496T3 (da) | 1991-08-26 | 2004-02-23 | Baxter Healthcare Sa | Rekombinant fjerkrækoppevirus med intakt FPV tk-gen |
| CA2122036C (en) * | 1991-10-23 | 2002-09-17 | Gillian Anlezark | Bacterial nitroreductase for the reduction of cb 1954 and analogues thereof to a cytotoxic form |
| DE4228458A1 (de) * | 1992-08-27 | 1994-06-01 | Beiersdorf Ag | Multicistronische Expressionseinheiten und deren Verwendung |
| WO1995004139A1 (en) | 1993-07-27 | 1995-02-09 | The Wistar Institute Of Anatomy And Biology | Modified dna virus vectors and uses therefor |
| AT403167B (de) * | 1994-11-14 | 1997-11-25 | Immuno Ag | Selektion und expression von fremdproteinen mittels eines selektions-amplifikations-systems |
| EP0753581A1 (en) | 1995-07-10 | 1997-01-15 | Immuno Ag | Improved recombinant eukaryotic cytoplasmic viruses, method for their production and their use as vaccines |
| ZA966287B (en) | 1995-07-27 | 1998-03-09 | American Cyanamid Co | Avirulent herpetic viruses useful as tumoricidal agents and vaccines. |
| WO1997014808A2 (en) | 1995-10-19 | 1997-04-24 | St. Jude Children's Research Hospital | Herpesvirus vectors and their uses |
| US5998174A (en) | 1997-05-12 | 1999-12-07 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Multigene vectors |
| GB9801930D0 (en) * | 1998-01-29 | 1998-03-25 | Univ London | Mutant herpes simplex viruses and uses thereof |
| US5922576A (en) * | 1998-02-27 | 1999-07-13 | The John Hopkins University | Simplified system for generating recombinant adenoviruses |
| US6602499B1 (en) * | 1998-04-30 | 2003-08-05 | The General Hospital Corporation | Combination viral-based and gene-based therapy of tumors |
| EP1153136A2 (en) | 1998-12-09 | 2001-11-14 | The General Hospital Corporation | Enhanced packaging of herpes virus amplicons and generation of recombinant virus vectors |
| PT1212428E (pt) * | 1999-08-31 | 2005-03-31 | Gen Hospital Corp | Redireccionamento da expressao do gene gama 34.5 de herpes atraves de um promotor especifico de celulas e/ou especifico de tumores |
| EP1111061A1 (en) * | 1999-12-20 | 2001-06-27 | Universite Libre De Bruxelles | Double selection vector |
| GB9930418D0 (en) | 1999-12-22 | 2000-02-16 | Neurovex Ltd | Replication incompetent herpes virus vectors |
| GB2375113B (en) * | 2000-01-21 | 2004-10-20 | Biovex Ltd | A modified, oncolytic, non-laboratory HSV strain and its use in treating cancer |
| JP2004535813A (ja) * | 2001-07-17 | 2004-12-02 | ミルナー，アン，ジョセフィーヌ | 遺伝子発現のサイレンシング |
| NZ531413A (en) * | 2001-08-21 | 2006-01-27 | Innovata Plc | Improved nitroreductase enzymes |
| US7348418B2 (en) | 2002-02-08 | 2008-03-25 | Memorial Sloan-Kettering Cancer Center | Carcinoma-related genes and polypeptides and methods of use thereof |
| GB0203285D0 (en) * | 2002-02-12 | 2002-03-27 | Brown Susanne M | An herpes simplex virus complex |
| CA2476724A1 (en) * | 2002-03-01 | 2003-09-12 | Sloan-Kettering Institute For Cancer Research | Prevention of recurrence and metastasis of cancer |
| US7288529B2 (en) * | 2003-04-24 | 2007-10-30 | New York University | ALK protein tyrosine kinase, cells and methods embodying and using same |
-
2003
- 2003-11-17 GB GBGB0326798.6A patent/GB0326798D0/en not_active Ceased
-
2004
- 2004-11-17 JP JP2006538966A patent/JP2007511215A/ja active Pending
- 2004-11-17 AT AT04798569T patent/ATE433493T1/de not_active IP Right Cessation
- 2004-11-17 AT AT04798619T patent/ATE484596T1/de not_active IP Right Cessation
- 2004-11-17 US US10/579,606 patent/US7498161B2/en not_active Expired - Lifetime
- 2004-11-17 DE DE602004029608T patent/DE602004029608D1/de not_active Expired - Lifetime
- 2004-11-17 WO PCT/GB2004/004839 patent/WO2005049844A2/en not_active Ceased
- 2004-11-17 WO PCT/GB2004/004851 patent/WO2005049845A2/en not_active Ceased
- 2004-11-17 DE DE602004021496T patent/DE602004021496D1/de not_active Expired - Lifetime
- 2004-11-17 US US10/579,607 patent/US20070110720A1/en not_active Abandoned
- 2004-11-17 EP EP04798569A patent/EP1685254B1/en not_active Expired - Lifetime
- 2004-11-17 EP EP04798558A patent/EP1692294A2/en not_active Withdrawn
- 2004-11-17 EP EP10186056A patent/EP2281897A3/en not_active Withdrawn
-
2009
- 2009-01-21 US US12/357,123 patent/US20090208460A1/en not_active Abandoned
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