JP2007503818A5 - - Google Patents

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Publication number
JP2007503818A5
JP2007503818A5 JP2006524947A JP2006524947A JP2007503818A5 JP 2007503818 A5 JP2007503818 A5 JP 2007503818A5 JP 2006524947 A JP2006524947 A JP 2006524947A JP 2006524947 A JP2006524947 A JP 2006524947A JP 2007503818 A5 JP2007503818 A5 JP 2007503818A5
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JP
Japan
Prior art keywords
metabolic
kit
product
analytes
substrates
Prior art date
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Application number
JP2006524947A
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English (en)
Japanese (ja)
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JP4838129B2 (ja
JP2007503818A (ja
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Priority claimed from US10/652,732 external-priority patent/US20050048499A1/en
Application filed filed Critical
Publication of JP2007503818A publication Critical patent/JP2007503818A/ja
Publication of JP2007503818A5 publication Critical patent/JP2007503818A5/ja
Application granted granted Critical
Publication of JP4838129B2 publication Critical patent/JP4838129B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2006524947A 2003-08-29 2004-08-30 代謝酵素活性及び代謝産物レベルの同時検出のための質量分析法 Expired - Fee Related JP4838129B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/652,732 US20050048499A1 (en) 2003-08-29 2003-08-29 Tandem mass spectrometry method for the genetic screening of inborn errors of metabolism in newborns
US10/652,732 2003-08-29
PCT/US2004/028238 WO2005021779A1 (en) 2003-08-29 2004-08-30 Mass spectrometry methods for simultaneous detection of metabolic enzyme activity and metabolite levels

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2011126859A Division JP2011167208A (ja) 2003-08-29 2011-06-07 代謝酵素活性及び代謝産物レベルの同時検出のための質量分析法

Publications (3)

Publication Number Publication Date
JP2007503818A JP2007503818A (ja) 2007-03-01
JP2007503818A5 true JP2007503818A5 (enExample) 2007-10-18
JP4838129B2 JP4838129B2 (ja) 2011-12-14

Family

ID=34217718

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2006524947A Expired - Fee Related JP4838129B2 (ja) 2003-08-29 2004-08-30 代謝酵素活性及び代謝産物レベルの同時検出のための質量分析法
JP2011126859A Pending JP2011167208A (ja) 2003-08-29 2011-06-07 代謝酵素活性及び代謝産物レベルの同時検出のための質量分析法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2011126859A Pending JP2011167208A (ja) 2003-08-29 2011-06-07 代謝酵素活性及び代謝産物レベルの同時検出のための質量分析法

Country Status (7)

Country Link
US (4) US20050048499A1 (enExample)
EP (1) EP1664325B1 (enExample)
JP (2) JP4838129B2 (enExample)
AU (1) AU2004269410B2 (enExample)
CA (1) CA2537034C (enExample)
ES (1) ES2527306T3 (enExample)
WO (1) WO2005021779A1 (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050048499A1 (en) * 2003-08-29 2005-03-03 Perkin Elmer Life Sciences, Inc. Tandem mass spectrometry method for the genetic screening of inborn errors of metabolism in newborns
US7485435B2 (en) * 2004-08-30 2009-02-03 Perkinelmer Las, Inc. Simultaneous detection of metabolic enzyme activity and metabolite levels
GB0409676D0 (en) * 2004-04-30 2004-06-02 Micromass Ltd Mass spectrometer
GB2413695B (en) * 2004-04-30 2009-01-21 Micromass Ltd Mass spectrometer
DE602005016899D1 (de) * 2005-05-20 2009-11-12 Germediq Forsch & Entw Ges Mbh Verfahren zur Bestimmung von kardiovaskulären Risikofaktoren
JP5005955B2 (ja) * 2006-05-24 2012-08-22 田辺三菱製薬株式会社 被験物質の脂質代謝異常症誘発可能性を予測する方法
AU2007299846B2 (en) 2006-09-19 2014-11-20 Metabolon, Inc. Biomarkers for prostate cancer and methods using the same
US7923257B2 (en) * 2007-05-04 2011-04-12 Perkinelmer Health Sciences, Inc. Detecting isomers using differential derivatization mass spectrometry
CN104076100A (zh) * 2007-06-29 2014-10-01 奎斯特诊断投资公司 用液相层析-质谱法分析体液内的氨基酸
WO2009071904A1 (en) * 2007-12-05 2009-06-11 King's College London Methods and compositions
FI20090100A0 (fi) * 2009-03-16 2009-03-16 Wallac Oy Biotinidaasimääritys
WO2015136264A1 (en) 2014-03-10 2015-09-17 Micromass Uk Limited Confirmation using multiple collision cross section ("ccs") measurements
KR20160140793A (ko) 2014-03-31 2016-12-07 세키스이 메디칼 가부시키가이샤 아실카르니틴 조성물
WO2016171182A1 (ja) * 2015-04-24 2016-10-27 株式会社資生堂 分析方法及び内部標準物質
JP6101385B2 (ja) * 2015-04-24 2017-03-22 株式会社 資生堂 分析方法
CN105510583A (zh) * 2015-11-25 2016-04-20 北京中科非凡生物技术有限公司 检测生物素酶酶活性的试剂盒
CN109416926A (zh) * 2016-04-11 2019-03-01 迪森德克斯公司 质谱数据分析工作流程
WO2018174858A1 (en) * 2017-03-21 2018-09-27 Mprobe Inc. Clinical method for the population screening of adult metabolic disorder associated with chronic human disease
CN111272888A (zh) * 2020-01-10 2020-06-12 山东英盛生物技术有限公司 一种新生儿血片中氨基酸及肉碱筛查预处理方法
US20220395767A1 (en) * 2021-06-15 2022-12-15 Perkinelmer Health Sciences, Inc. Enhancing lcms analyte signals
CN114121275B (zh) * 2021-11-02 2024-09-27 浙江大学 一种基于大数据遗传代谢病筛查效率提升的智能分析方法
EP4679082A1 (en) 2024-07-10 2026-01-14 Masdiag Sp. z o.o. Method for improved determination of the acylcarnitine profile in biological material

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5096812A (en) * 1989-06-08 1992-03-17 Osborn Laboratories, Inc. Assay method for gamma glutamyltransferase (GGT) in liquid blood and dried blood
US5538857A (en) * 1994-06-01 1996-07-23 Isolab, Inc. Assay for enzyme activity from a red blood sample using a direct microfluorometric assay
US5629210A (en) * 1995-06-02 1997-05-13 University Of Pittsburgh Of The Commonwealth System Of Higher Education Rapid screening test for smith-lemli-opitz syndrome
ATE253126T1 (de) * 1998-08-25 2003-11-15 Univ Washington Schnelle quantitative analyse von proteinen oder proteinfunktionen in komplexen gemischen
EP1125136B1 (en) 1998-10-30 2006-05-31 Burstein Technologies, Inc. Trackable optical discs with concurrently readable analyte material
US6455321B1 (en) * 1999-01-30 2002-09-24 Neo Gen Screening, Inc. Method for interpreting tandem mass spectrometry data for clinical diagnosis
US6258605B1 (en) * 1999-03-26 2001-07-10 Neo Gen Screening, Inc. Clinical method for the genetic screening of newborns using tandem mass spectrometry
ATE343130T1 (de) 1999-12-29 2006-11-15 Perkinelmer Life Sciences Inc Testtablett, kit und verfahren zum screening von körperflüssigkeiten von neugeborenen durch tandem-massenspektrometrie
US20050048499A1 (en) 2003-08-29 2005-03-03 Perkin Elmer Life Sciences, Inc. Tandem mass spectrometry method for the genetic screening of inborn errors of metabolism in newborns

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