ES2527306T3 - Métodos de espectrometría de masas para la detección simultánea de actividad de enzimas metabólicas y niveles de metabolitos - Google Patents
Métodos de espectrometría de masas para la detección simultánea de actividad de enzimas metabólicas y niveles de metabolitos Download PDFInfo
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- ES2527306T3 ES2527306T3 ES04782672.2T ES04782672T ES2527306T3 ES 2527306 T3 ES2527306 T3 ES 2527306T3 ES 04782672 T ES04782672 T ES 04782672T ES 2527306 T3 ES2527306 T3 ES 2527306T3
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
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- G—PHYSICS
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| US652732 | 2003-08-29 | ||
| PCT/US2004/028238 WO2005021779A1 (en) | 2003-08-29 | 2004-08-30 | Mass spectrometry methods for simultaneous detection of metabolic enzyme activity and metabolite levels |
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| US7485435B2 (en) * | 2004-08-30 | 2009-02-03 | Perkinelmer Las, Inc. | Simultaneous detection of metabolic enzyme activity and metabolite levels |
| JP5009784B2 (ja) * | 2004-04-30 | 2012-08-22 | マイクロマス ユーケー リミテッド | 質量分析計 |
| GB0409676D0 (en) * | 2004-04-30 | 2004-06-02 | Micromass Ltd | Mass spectrometer |
| DE602005016899D1 (de) * | 2005-05-20 | 2009-11-12 | Germediq Forsch & Entw Ges Mbh | Verfahren zur Bestimmung von kardiovaskulären Risikofaktoren |
| JP5005955B2 (ja) * | 2006-05-24 | 2012-08-22 | 田辺三菱製薬株式会社 | 被験物質の脂質代謝異常症誘発可能性を予測する方法 |
| EP2061899B1 (en) * | 2006-09-19 | 2012-08-29 | Metabolon Inc. | Biomarkers for prostate cancer and methods using the same |
| US7923257B2 (en) * | 2007-05-04 | 2011-04-12 | Perkinelmer Health Sciences, Inc. | Detecting isomers using differential derivatization mass spectrometry |
| CN101796408B (zh) * | 2007-06-29 | 2014-05-07 | 奎斯特诊断投资公司 | 用液相层析-质谱法分析体液内的氨基酸 |
| AU2008332886B2 (en) * | 2007-12-05 | 2014-10-09 | Spoton Clinical Diagnostics Limited | Methods and compositions |
| FI20090100A0 (fi) * | 2009-03-16 | 2009-03-16 | Wallac Oy | Biotinidaasimääritys |
| DE112015001169T5 (de) | 2014-03-10 | 2016-12-22 | Micromass Uk Limited | Bestätigung unter Verwendung einer Mehrzahl von Kollisionsquerschnitts-("CCS")-Messungen |
| WO2015152234A1 (ja) | 2014-03-31 | 2015-10-08 | 積水メディカル株式会社 | アシルカルニチン組成物 |
| JP6101385B2 (ja) * | 2015-04-24 | 2017-03-22 | 株式会社 資生堂 | 分析方法 |
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| CN105510583A (zh) * | 2015-11-25 | 2016-04-20 | 北京中科非凡生物技术有限公司 | 检测生物素酶酶活性的试剂盒 |
| EP3443497A1 (en) * | 2016-04-11 | 2019-02-20 | DiscernDx, Inc. | Mass spectrometric data analysis workflow |
| WO2018174858A1 (en) * | 2017-03-21 | 2018-09-27 | Mprobe Inc. | Clinical method for the population screening of adult metabolic disorder associated with chronic human disease |
| CN111272888A (zh) * | 2020-01-10 | 2020-06-12 | 山东英盛生物技术有限公司 | 一种新生儿血片中氨基酸及肉碱筛查预处理方法 |
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| CN114121275B (zh) * | 2021-11-02 | 2024-09-27 | 浙江大学 | 一种基于大数据遗传代谢病筛查效率提升的智能分析方法 |
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| US5629210A (en) * | 1995-06-02 | 1997-05-13 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Rapid screening test for smith-lemli-opitz syndrome |
| ATE253126T1 (de) * | 1998-08-25 | 2003-11-15 | Univ Washington | Schnelle quantitative analyse von proteinen oder proteinfunktionen in komplexen gemischen |
| WO2000026677A1 (en) | 1998-10-30 | 2000-05-11 | Burstein Laboratories, Inc. | Trackable optical discs with concurrently readable analyte material |
| US6455321B1 (en) * | 1999-01-30 | 2002-09-24 | Neo Gen Screening, Inc. | Method for interpreting tandem mass spectrometry data for clinical diagnosis |
| US6258605B1 (en) * | 1999-03-26 | 2001-07-10 | Neo Gen Screening, Inc. | Clinical method for the genetic screening of newborns using tandem mass spectrometry |
| DE60031357T2 (de) * | 1999-12-29 | 2007-08-30 | PerkinElmer Life Sciences, Inc., Norton | Geräte, Kits und Verfahren zum Testen von Körperflüssigkeiten zum Screening vonNeugeborenen durch Tandem-Massenspektrometrie-Kits |
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| US20120122131A1 (en) | 2012-05-17 |
| CA2537034A1 (en) | 2005-03-10 |
| EP1664325B1 (en) | 2014-10-08 |
| JP2011167208A (ja) | 2011-09-01 |
| US20060234326A1 (en) | 2006-10-19 |
| US8399186B2 (en) | 2013-03-19 |
| JP4838129B2 (ja) | 2011-12-14 |
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