WO2006025863A3 - Simultaneous detection of metabolic enzyme activity and metabolite levels - Google Patents
Simultaneous detection of metabolic enzyme activity and metabolite levels Download PDFInfo
- Publication number
- WO2006025863A3 WO2006025863A3 PCT/US2005/006371 US2005006371W WO2006025863A3 WO 2006025863 A3 WO2006025863 A3 WO 2006025863A3 US 2005006371 W US2005006371 W US 2005006371W WO 2006025863 A3 WO2006025863 A3 WO 2006025863A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- metabolic
- product
- enzymes
- enzyme activity
- analytes
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6848—Methods of protein analysis involving mass spectrometry
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/04—Endocrine or metabolic disorders
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Computational Biology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Cell Biology (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/539,180 US7485435B2 (en) | 2004-08-30 | 2005-02-28 | Simultaneous detection of metabolic enzyme activity and metabolite levels |
US12/349,669 US8318417B2 (en) | 2003-08-29 | 2009-01-07 | Simultaneous detection of metabolic enzyme activity and metabolite levels |
US13/357,324 US8399186B2 (en) | 2003-08-29 | 2012-01-24 | Simultaneous detection of metabolic enzyme activity and metabolite levels |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US2004/028238 WO2005021779A1 (en) | 2003-08-29 | 2004-08-30 | Mass spectrometry methods for simultaneous detection of metabolic enzyme activity and metabolite levels |
USPCT/US04/28238 | 2004-08-30 |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/652,732 Continuation US20050048499A1 (en) | 2003-08-29 | 2003-08-29 | Tandem mass spectrometry method for the genetic screening of inborn errors of metabolism in newborns |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/539,180 A-371-Of-International US7485435B2 (en) | 2003-08-29 | 2005-02-28 | Simultaneous detection of metabolic enzyme activity and metabolite levels |
US12/349,669 Continuation US8318417B2 (en) | 2003-08-29 | 2009-01-07 | Simultaneous detection of metabolic enzyme activity and metabolite levels |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2006025863A2 WO2006025863A2 (en) | 2006-03-09 |
WO2006025863A3 true WO2006025863A3 (en) | 2007-11-22 |
Family
ID=36000463
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2005/006371 WO2006025863A2 (en) | 2003-08-29 | 2005-02-28 | Simultaneous detection of metabolic enzyme activity and metabolite levels |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2006025863A2 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8628936B2 (en) | 2007-12-05 | 2014-01-14 | King's College London | Methods and compositions for multiplexed screening of disease |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5096812A (en) * | 1989-06-08 | 1992-03-17 | Osborn Laboratories, Inc. | Assay method for gamma glutamyltransferase (GGT) in liquid blood and dried blood |
US6258605B1 (en) * | 1999-03-26 | 2001-07-10 | Neo Gen Screening, Inc. | Clinical method for the genetic screening of newborns using tandem mass spectrometry |
US6455321B1 (en) * | 1999-01-30 | 2002-09-24 | Neo Gen Screening, Inc. | Method for interpreting tandem mass spectrometry data for clinical diagnosis |
-
2005
- 2005-02-28 WO PCT/US2005/006371 patent/WO2006025863A2/en active Application Filing
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5096812A (en) * | 1989-06-08 | 1992-03-17 | Osborn Laboratories, Inc. | Assay method for gamma glutamyltransferase (GGT) in liquid blood and dried blood |
US6455321B1 (en) * | 1999-01-30 | 2002-09-24 | Neo Gen Screening, Inc. | Method for interpreting tandem mass spectrometry data for clinical diagnosis |
US6258605B1 (en) * | 1999-03-26 | 2001-07-10 | Neo Gen Screening, Inc. | Clinical method for the genetic screening of newborns using tandem mass spectrometry |
Also Published As
Publication number | Publication date |
---|---|
WO2006025863A2 (en) | 2006-03-09 |
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