JP2007503268A - 免疫応答修飾化合物の送達 - Google Patents
免疫応答修飾化合物の送達 Download PDFInfo
- Publication number
- JP2007503268A JP2007503268A JP2006524827A JP2006524827A JP2007503268A JP 2007503268 A JP2007503268 A JP 2007503268A JP 2006524827 A JP2006524827 A JP 2006524827A JP 2006524827 A JP2006524827 A JP 2006524827A JP 2007503268 A JP2007503268 A JP 2007503268A
- Authority
- JP
- Japan
- Prior art keywords
- irm
- substituted
- amine
- microneedle
- irm compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0021—Intradermal administration, e.g. through microneedle arrays or needleless injectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0046—Solid microneedles
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Anesthesiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49762803P | 2003-08-25 | 2003-08-25 | |
| PCT/US2004/027633 WO2005020912A2 (en) | 2003-08-25 | 2004-08-25 | Delivery of immune response modifier compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007503268A true JP2007503268A (ja) | 2007-02-22 |
| JP2007503268A5 JP2007503268A5 (enExample) | 2007-11-22 |
Family
ID=34272589
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006524827A Pending JP2007503268A (ja) | 2003-08-25 | 2004-08-25 | 免疫応答修飾化合物の送達 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8961477B2 (enExample) |
| EP (1) | EP1658035A4 (enExample) |
| JP (1) | JP2007503268A (enExample) |
| AU (2) | AU2004268616B2 (enExample) |
| CA (1) | CA2536249A1 (enExample) |
| WO (1) | WO2005020912A2 (enExample) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009506013A (ja) * | 2005-08-24 | 2009-02-12 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 医薬品送達用の経角膜システム |
| JP2023502618A (ja) * | 2019-11-18 | 2023-01-25 | オー. リハチョフ,エム.ディー.,アナ | 治療用アプリケータを非均一的な表面に整合させるためのシステム |
| KR102968936B1 (ko) | 2019-11-18 | 2026-05-22 | 엠.디. 안나 오. 리카체바 | 치료 어플리케이터를 불균일한 표면에 일치시키기 위한 시스템 |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US20040265351A1 (en) | 2003-04-10 | 2004-12-30 | Miller Richard L. | Methods and compositions for enhancing immune response |
| JP2007503268A (ja) | 2003-08-25 | 2007-02-22 | スリーエム イノベイティブ プロパティズ カンパニー | 免疫応答修飾化合物の送達 |
| NZ545412A (en) | 2003-08-27 | 2008-12-24 | Coley Pharm Group Inc | Aryloxy and arylalkyleneoxy substituted imidazoquinolines |
| EP1673087B1 (en) | 2003-10-03 | 2015-05-13 | 3M Innovative Properties Company | Alkoxy substituted imidazoquinolines |
| KR101494056B1 (ko) | 2003-10-03 | 2015-02-16 | 쓰리엠 이노베이티브 프로퍼티즈 컴파니 | 피라졸로피리딘 및 그의 유사체 |
| AU2004293078B2 (en) | 2003-11-25 | 2012-01-19 | 3M Innovative Properties Company | Substituted imidazo ring systems and methods |
| US8541438B2 (en) | 2004-06-18 | 2013-09-24 | 3M Innovative Properties Company | Substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines |
| CA2592904C (en) | 2004-12-30 | 2015-04-07 | 3M Innovative Properties Company | Chiral fused [1,2]imidazo[4,5-c] ring compounds |
| JP5313502B2 (ja) | 2004-12-30 | 2013-10-09 | スリーエム イノベイティブ プロパティズ カンパニー | 置換キラル縮合[1,2]イミダゾ[4,5−c]環状化合物 |
| JP5191740B2 (ja) * | 2005-01-28 | 2013-05-08 | ガレンバイオ、インコーポレイテッド | 免疫学的に活性な組成物 |
| CA2602083A1 (en) | 2005-02-09 | 2006-08-09 | Coley Pharmaceutical Group, Inc. | Oxime and hydroxylamine substituted thiazolo(4,5-c) ring compounds and methods |
| US20080318998A1 (en) | 2005-02-09 | 2008-12-25 | Coley Pharmaceutical Group, Inc. | Alkyloxy Substituted Thiazoloquinolines and Thiazolonaphthyridines |
| CA2597446A1 (en) | 2005-02-11 | 2006-08-31 | Coley Pharmaceutical Group, Inc. | Substituted imidazoquinolines and imidazonaphthyridines |
| CA2598639A1 (en) | 2005-02-23 | 2006-08-31 | Coley Pharmaceutical Group, Inc. | Hydroxyalkyl substituted imidazonaphthyridines |
| AU2006223634A1 (en) | 2005-02-23 | 2006-09-21 | Coley Pharmaceutical Group, Inc. | Hydroxyalkyl substituted imidazoquinolines |
| EP1851218A2 (en) | 2005-02-23 | 2007-11-07 | 3M Innovative Properties Company | Hydroxyalkyl substituted imidazoquinoline compounds and methods |
| AU2006216686A1 (en) | 2005-02-23 | 2006-08-31 | Coley Pharmaceutical Group, Inc. | Method of preferentially inducing the biosynthesis of interferon |
| ZA200803029B (en) | 2005-09-09 | 2009-02-25 | Coley Pharm Group Inc | Amide and carbamate derivatives of alkyl substituted /V-[4-(4-amino-1H-imidazo[4,5-c] quinolin-1-yl)butyl] methane-sulfonamides and methods |
| AU2006287270A1 (en) | 2005-09-09 | 2007-03-15 | Coley Pharmaceutical Group, Inc. | Amide and carbamate derivatives of N-{2-[4-amino-2- (ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-1,1-dimethylethyl}methanesulfonamide and methods |
| WO2007056112A2 (en) | 2005-11-04 | 2007-05-18 | Coley Pharmaceutical Group, Inc. | Hydroxy and alkoxy substituted 1h-imidazoquinolines and methods |
| WO2007056527A2 (en) * | 2005-11-09 | 2007-05-18 | Cheng Si Yuan (China-International) Hepatitis Research Foundation | Diagnostic and therapeutic methods and agents |
| EP1988896A4 (en) | 2006-02-22 | 2011-07-27 | 3M Innovative Properties Co | CONJUGATES TO MODIFY IMMUNE REACTIONS |
| WO2007106854A2 (en) | 2006-03-15 | 2007-09-20 | Coley Pharmaceutical Group, Inc. | Hydroxy and alkoxy substituted 1h-imidazonaphthyridines and methods |
| US20090182306A1 (en) * | 2006-07-21 | 2009-07-16 | Georgia Tech Research Corporation | Microneedle Devices and Methods of Drug Delivery or Fluid Withdrawal |
| US8178539B2 (en) | 2006-09-06 | 2012-05-15 | 3M Innovative Properties Company | Substituted 3,4,6,7-tetrahydro-5H-1,2a,4a,8-tetraazacyclopenta[cd]phenalenes and methods |
| JP5331100B2 (ja) * | 2007-04-25 | 2013-10-30 | イミュアールエックス・インコーポレーテッド | Nktアクチベータ、cd40アゴニスト、及び任意選択的に抗原を含んでなるアジュバント組合せと、細胞性免疫において相乗的な増強を誘導するためのその使用 |
| EP2173431A4 (en) * | 2007-07-09 | 2013-06-12 | Apogee Technology Inc | IMMUNOSTIMULATING POLYPHOSPHAZEN COMPOUNDS FOR INTRADERMAL IMMUNIZATION |
| US20090016935A1 (en) * | 2007-07-09 | 2009-01-15 | Andrianov Alexander K | Coating formulations including polyphosphazene polyelectrolytes and biologically active agents and asperities coated with such formulations |
| US20100160368A1 (en) * | 2008-08-18 | 2010-06-24 | Gregory Jefferson J | Methods of Treating Dermatological Disorders and Inducing Interferon Biosynthesis With Shorter Durations of Imiquimod Therapy |
| MX336923B (es) | 2009-07-13 | 2016-02-05 | Medicis Pharmaceutical Corp | Formulaciones de imiquimod de concentracion de dosificacion inferior y regimenes de dosificacion cortos para tratar verrugas genitales y perianales. |
| CN102917722B (zh) | 2010-05-28 | 2018-05-22 | 3M创新有限公司 | 用于涂布微针阵列的水性制剂 |
| LT2606047T (lt) | 2010-08-17 | 2017-04-10 | 3M Innovative Properties Company | Imuninio atsako modifikatoriaus junginio lipidizuotos kompozicijos, sudėtys ir būdai |
| CA2838023C (en) | 2011-06-03 | 2019-08-13 | 3M Innovative Properties Company | Hydrazino 1h-imidazoquinolin-4-amines and conjugates made therefrom |
| EP2717919B1 (en) | 2011-06-03 | 2016-08-03 | 3M Innovative Properties Company | Heterobifunctional linkers with polyethylene glycol segments and immune response modifier conjugates made therefrom |
| KR102080061B1 (ko) * | 2011-06-24 | 2020-02-21 | 플루젠, 인코퍼레이티드 | 인플루엔자 바이러스 돌연변이체들 및 그들의 용도들 |
| US20130096532A1 (en) * | 2011-10-17 | 2013-04-18 | Rutgers, The State University Of New Jersey | Polymer-Based Micro-Needle Array Designs, Fabrication Processes, and Methods of Use Thereof for Drug Delivery |
| US10821276B2 (en) * | 2012-12-14 | 2020-11-03 | The Trustees Of Columbia University In The City Of New York | System and method to locally deliver therapeutic agent to inner ear |
| KR101724655B1 (ko) * | 2014-06-02 | 2017-04-13 | 주식회사 아모라이프사이언스 | 마이크로 니들 패치 및 그의 제조 방법 |
| EP3250228A1 (en) | 2015-01-27 | 2017-12-06 | 3M Innovative Properties Company | Alum-containing coating formulations for microneedle vaccine patches |
| SG11201706835WA (en) | 2015-03-16 | 2017-09-28 | Hoffmann La Roche | Combined treatment with a tlr7 agonist and an hbv capsid assembly inhibitor |
| ES2909043T3 (es) | 2015-10-09 | 2022-05-05 | Kindeva Drug Delivery Lp | Composiciones de zinc para sistemas de microagujas recubiertos |
| SG11201802769RA (en) | 2015-10-29 | 2018-05-30 | Novartis Ag | Antibody conjugates comprising toll-like receptor agonist |
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| EP3728255B1 (en) | 2017-12-20 | 2022-01-26 | 3M Innovative Properties Company | Amide substituted imidazo[4,5-c]quinoline compounds with a branched chain linking group for use as an immune response modifier |
| US11844919B2 (en) | 2018-01-03 | 2023-12-19 | The Trustees Of Columbia University In The City Of New York | Microneedle for local delivery of therapeutic agent |
| EP3804696A1 (en) * | 2019-10-07 | 2021-04-14 | Unigroup ApS | A multi-component wart destructing means |
| US20230073125A1 (en) * | 2019-10-29 | 2023-03-09 | The Regents Of The University Of California | Periodontal micropatch and uses thereof |
| KR20230013274A (ko) * | 2020-05-21 | 2023-01-26 | 백세스 테크놀로지스, 인코포레이티드 | 백신 방출을 위한 조성물 및 장치 및 그의 용도 |
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| JP2009506013A (ja) * | 2005-08-24 | 2009-02-12 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 医薬品送達用の経角膜システム |
| JP2023502618A (ja) * | 2019-11-18 | 2023-01-25 | オー. リハチョフ,エム.ディー.,アナ | 治療用アプリケータを非均一的な表面に整合させるためのシステム |
| JP2025118618A (ja) * | 2019-11-18 | 2025-08-13 | オー. リハチョフ,エム.ディー.,アナ | 治療用アプリケータを非均一的な表面に整合させるためのシステム |
| JP7728590B2 (ja) | 2019-11-18 | 2025-08-25 | オー. リハチョフ,エム.ディー.,アナ | 治療用アプリケータを非均一的な表面に整合させるためのシステム |
| KR102968936B1 (ko) | 2019-11-18 | 2026-05-22 | 엠.디. 안나 오. 리카체바 | 치료 어플리케이터를 불균일한 표면에 일치시키기 위한 시스템 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005020912A3 (en) | 2006-03-30 |
| AU2004268616A1 (en) | 2005-03-10 |
| US20060195067A1 (en) | 2006-08-31 |
| AU2010224314A1 (en) | 2010-10-14 |
| CA2536249A1 (en) | 2005-03-10 |
| US8961477B2 (en) | 2015-02-24 |
| AU2004268616B2 (en) | 2010-10-07 |
| WO2005020912A2 (en) | 2005-03-10 |
| EP1658035A4 (en) | 2007-08-22 |
| EP1658035A2 (en) | 2006-05-24 |
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