JP2007501627A5 - - Google Patents
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- Publication number
- JP2007501627A5 JP2007501627A5 JP2006523302A JP2006523302A JP2007501627A5 JP 2007501627 A5 JP2007501627 A5 JP 2007501627A5 JP 2006523302 A JP2006523302 A JP 2006523302A JP 2006523302 A JP2006523302 A JP 2006523302A JP 2007501627 A5 JP2007501627 A5 JP 2007501627A5
- Authority
- JP
- Japan
- Prior art keywords
- subject
- allele
- genotype
- osteoporosis
- onset
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000000034 method Methods 0.000 claims 15
- 108700028369 Alleles Proteins 0.000 claims 14
- 208000001132 Osteoporosis Diseases 0.000 claims 9
- 101001033249 Homo sapiens Interleukin-1 beta Proteins 0.000 claims 6
- 102100039065 Interleukin-1 beta Human genes 0.000 claims 6
- 101710144554 Interleukin-1 receptor antagonist protein Proteins 0.000 claims 6
- 102100026018 Interleukin-1 receptor antagonist protein Human genes 0.000 claims 6
- 101001002634 Homo sapiens Interleukin-1 alpha Proteins 0.000 claims 4
- 102100020881 Interleukin-1 alpha Human genes 0.000 claims 4
- 108091034117 Oligonucleotide Proteins 0.000 claims 4
- 238000001514 detection method Methods 0.000 claims 3
- 238000009396 hybridization Methods 0.000 claims 3
- 230000003321 amplification Effects 0.000 claims 2
- 238000003199 nucleic acid amplification method Methods 0.000 claims 2
- 101710163270 Nuclease Proteins 0.000 claims 1
- 238000004458 analytical method Methods 0.000 claims 1
- 238000003556 assay Methods 0.000 claims 1
- 230000029087 digestion Effects 0.000 claims 1
- 238000002657 hormone replacement therapy Methods 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 206010041569 spinal fracture Diseases 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49386103P | 2003-08-08 | 2003-08-08 | |
| PCT/US2004/025858 WO2005013809A2 (en) | 2003-08-08 | 2004-08-09 | Diagnostic and therapeutics for osteoporosis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007501627A JP2007501627A (ja) | 2007-02-01 |
| JP2007501627A5 true JP2007501627A5 (enExample) | 2007-03-29 |
Family
ID=34135292
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006523302A Withdrawn JP2007501627A (ja) | 2003-08-08 | 2004-08-09 | 骨粗鬆症のための診断法および治療法 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7723028B2 (enExample) |
| EP (1) | EP1680513B1 (enExample) |
| JP (1) | JP2007501627A (enExample) |
| KR (1) | KR20060061350A (enExample) |
| CN (1) | CN1863928A (enExample) |
| AT (1) | ATE490339T1 (enExample) |
| AU (1) | AU2004263184B2 (enExample) |
| CA (1) | CA2534365A1 (enExample) |
| DE (1) | DE602004030367D1 (enExample) |
| WO (1) | WO2005013809A2 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090023147A1 (en) * | 1999-08-30 | 2009-01-22 | Kenneth Kornman | Diagnostics and therapeutics for osteoporosis |
| US20070264645A1 (en) * | 2002-01-25 | 2007-11-15 | Kenneth Kornman | IL-1 gene cluster and associated inflammatory polymorphisms and haplotypes |
| CN1863928A (zh) | 2003-08-08 | 2006-11-15 | 英特利金遗传学有限公司 | 骨质疏松的诊断和治疗 |
| US8105775B2 (en) * | 2005-10-25 | 2012-01-31 | Interleukin Genetics, Inc. | IL-1 gene cluster and associated inflammatory polymorphisms and haplotypes |
| CA2668722A1 (en) * | 2006-11-15 | 2008-05-22 | Interleukin Genetics, Inc. | The il-1 gene cluster, insulin resistance and coronary artery disease associated polymorphisms and haplotypes and methods of using same |
| KR100909709B1 (ko) * | 2007-03-30 | 2009-07-30 | 대한민국 | 골밀도 및 골절 위험과 ｉｔｇａ１ 유전자 다형성과의연관성 |
| US20100112570A1 (en) * | 2008-10-22 | 2010-05-06 | Interleukin Genetics, Inc. | Genetic Markers for Weight Management and Methods of Use Thereof |
| WO2010083294A2 (en) * | 2009-01-16 | 2010-07-22 | Interleukin Genetics, Inc. | Diagnostics and therapeutics for osteoporosis |
| JP2019503176A (ja) | 2016-01-12 | 2019-02-07 | インターロイキン ジェネティクス， インコーポレイテッド | 処置に対する応答を予測するための方法 |
| US10329620B2 (en) | 2017-01-12 | 2019-06-25 | Cardioforecast Ltd. | Methods and kits for treating cardiovascular disease |
| CA3142662A1 (en) | 2019-06-06 | 2020-12-10 | Sitokine Limited | Compositions and methods for treating lung, colorectal and breast cancer |
| WO2021028469A1 (en) | 2019-08-12 | 2021-02-18 | Sitokine Limited | Compositions and methods for treating cytokine release syndrome and neurotoxicity |
| WO2021205013A1 (en) | 2020-04-09 | 2021-10-14 | Sitokine Limited | Compositions and methods for treating covid-19 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8311018D0 (en) | 1983-04-22 | 1983-05-25 | Amersham Int Plc | Detecting mutations in dna |
| US4833080A (en) | 1985-12-12 | 1989-05-23 | President And Fellows Of Harvard College | Regulation of eucaryotic gene expression |
| US4998617A (en) | 1986-09-15 | 1991-03-12 | Laura Lupton Inc | Facial cosmetic liquid make up kit |
| CA1316520C (en) | 1987-05-19 | 1993-04-20 | Larry C. Hamilton | Valve |
| US4968607A (en) | 1987-11-25 | 1990-11-06 | Immunex Corporation | Interleukin-1 receptors |
| US5459039A (en) | 1989-05-12 | 1995-10-17 | Duke University | Methods for mapping genetic mutations |
| FR2650840B1 (fr) | 1989-08-11 | 1991-11-29 | Bertin & Cie | Procede rapide de detection et/ou d'identification d'une seule base sur une sequence d'acide nucleique, et ses applications |
| US6004744A (en) | 1991-03-05 | 1999-12-21 | Molecular Tool, Inc. | Method for determining nucleotide identity through extension of immobilized primer |
| WO1992015694A1 (en) | 1991-03-08 | 1992-09-17 | The Salk Institute For Biological Studies | Flp-mediated gene modification in mammalian cells, and compositions and cells useful therefor |
| WO1993011149A1 (en) | 1991-12-03 | 1993-06-10 | Thomas Jefferson University | Methods of detecting a genetic predisposition for osteoporosis |
| US5593833A (en) | 1992-07-31 | 1997-01-14 | Garvan Institute Of Medical Research | Assessment of allelic variation in vitamin D receptor correlated to bone density or turnover |
| JP3472587B2 (ja) | 1992-08-28 | 2003-12-02 | アベンティス ファーマ株式会社 | 骨関連カルボキシペプチダーゼ様タンパク質およびその製造法 |
| EP0675903B1 (en) | 1992-12-28 | 2004-09-29 | David J Baylink | Bone resorption assay |
| EP0679196B1 (en) | 1993-01-07 | 2004-05-26 | Sequenom, Inc. | Dna sequencing by mass spectrometry |
| IL108947A0 (en) | 1993-03-12 | 1994-06-24 | Osteopharm Ltd | Bone stimulating factor |
| US5593826A (en) | 1993-03-22 | 1997-01-14 | Perkin-Elmer Corporation, Applied Biosystems, Inc. | Enzymatic ligation of 3'amino-substituted oligonucleotides |
| CA2164498C (en) | 1993-07-09 | 2007-09-11 | Paul A. Price | Assay for ykl-40 as a marker for degradation of mammalian connective tissue matrices |
| US5686246A (en) | 1995-08-03 | 1997-11-11 | Kornman; Kenneth S. | Detecting genetic predisposition to periodontal disease |
| US5942390A (en) | 1996-01-12 | 1999-08-24 | Cedars-Sinai Medical Center | Method of diagnosing predisposition for ulcerative colitis in Jewish population by detection of interleukin-1 receptor antagonist polymorphism |
| US5698399A (en) | 1996-04-05 | 1997-12-16 | Duff; Gordon W. | Detecting genetic predisposition for osteoporosis |
| GB9621129D0 (en) | 1996-10-10 | 1996-11-27 | Duff Gordon W | Detecting genetic predisposition to sight-threatening diabetic retinopathy |
| GB9706359D0 (en) | 1997-03-27 | 1997-05-14 | Gemini International Holdings | Polymorphisms of an il-1 receptor antagonist gene |
| GB9711040D0 (en) | 1997-05-29 | 1997-07-23 | Duff Gordon W | Prediction of inflammatory disease |
| EP1212464B1 (en) | 1999-08-30 | 2006-02-22 | Interleukin Genetics, Inc. | Diagnostics and therapeutics for osteoporosis |
| JP2002345500A (ja) * | 2000-12-22 | 2002-12-03 | Pfizer Prod Inc | 炎症性障害を発展させる増加したリスクを検出するための方法および試薬 |
| JP2005500032A (ja) * | 2001-06-15 | 2005-01-06 | インターリューキン ジェネティックス インコーポレイテッド | 老化関連症状の早期発現を検出および治療する方法 |
| CN1863928A (zh) | 2003-08-08 | 2006-11-15 | 英特利金遗传学有限公司 | 骨质疏松的诊断和治疗 |
-
2004
- 2004-08-09 CN CNA2004800291247A patent/CN1863928A/zh active Pending
- 2004-08-09 WO PCT/US2004/025858 patent/WO2005013809A2/en not_active Ceased
- 2004-08-09 CA CA002534365A patent/CA2534365A1/en not_active Abandoned
- 2004-08-09 KR KR1020067002708A patent/KR20060061350A/ko not_active Ceased
- 2004-08-09 DE DE602004030367T patent/DE602004030367D1/de not_active Expired - Lifetime
- 2004-08-09 US US10/914,396 patent/US7723028B2/en not_active Expired - Lifetime
- 2004-08-09 AU AU2004263184A patent/AU2004263184B2/en not_active Ceased
- 2004-08-09 EP EP04780660A patent/EP1680513B1/en not_active Expired - Lifetime
- 2004-08-09 JP JP2006523302A patent/JP2007501627A/ja not_active Withdrawn
- 2004-08-09 AT AT04780660T patent/ATE490339T1/de not_active IP Right Cessation
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