JP2007501305A - 血漿中で高度の抗血栓活性を有する多糖類誘導体 - Google Patents
血漿中で高度の抗血栓活性を有する多糖類誘導体 Download PDFInfo
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- JP2007501305A JP2007501305A JP2006522341A JP2006522341A JP2007501305A JP 2007501305 A JP2007501305 A JP 2007501305A JP 2006522341 A JP2006522341 A JP 2006522341A JP 2006522341 A JP2006522341 A JP 2006522341A JP 2007501305 A JP2007501305 A JP 2007501305A
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
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- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
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- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
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| IT001618A ITMI20031618A1 (it) | 2003-08-06 | 2003-08-06 | Derivati polisaccaridici dotati di alta attivita' |
| PCT/EP2004/051391 WO2005014656A1 (en) | 2003-08-06 | 2004-07-07 | Polysaccharides derivatives with high antithrombotic activity in plasma |
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| JP2007501305A true JP2007501305A (ja) | 2007-01-25 |
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| CA (1) | CA2534709A1 (https=) |
| DE (1) | DE602004025583D1 (https=) |
| DK (1) | DK1654288T3 (https=) |
| ES (1) | ES2341249T3 (https=) |
| IL (1) | IL173482A0 (https=) |
| IT (1) | ITMI20031618A1 (https=) |
| MX (1) | MXPA06001511A (https=) |
| RU (1) | RU2361881C2 (https=) |
| WO (1) | WO2005014656A1 (https=) |
| ZA (1) | ZA200601643B (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013503606A (ja) * | 2009-09-01 | 2013-02-04 | レンセラー ポリテクニック インスティチュート | Ｋ５ヘパロサン発酵および精製 |
| WO2017115674A1 (ja) * | 2015-12-28 | 2017-07-06 | 味の素株式会社 | 抗凝固活性を有するヘパラン硫酸の製造法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2007058592A1 (en) * | 2005-11-21 | 2007-05-24 | Ge Healthcare Bio-Sciences Ab | A method of chromatography using semi-synthetic heparin ligands |
| GB0818255D0 (en) | 2008-10-06 | 2008-11-12 | Agency Science Tech & Res | Isolation and identification of glycosaminoglycans |
| US9498494B2 (en) | 2008-09-11 | 2016-11-22 | Agency For Science, Technology And Research | Glycosaminoglycans |
| CN101698838B (zh) * | 2008-12-26 | 2012-05-23 | 北京大学 | 尿苷二磷酸葡萄糖醛酸异构酶及其编码基因与应用 |
| ITMI20091445A1 (it) * | 2009-08-07 | 2011-02-08 | Inalco S P A A Socio Unico | Derivati semi-sintetici del polisaccaride k5 per la prevenzione ed il trattamento del danno tissutale associato a ischemia e/o riperfusione |
| EP2598652A4 (en) | 2010-07-29 | 2014-04-30 | Shire Human Genetic Therapies | TESTS FOR THE DETECTION OF GLYCOSAMINOGLYCANES |
| EP2809796A4 (en) * | 2012-02-01 | 2016-08-17 | Shire Human Genetic Therapies | TESTS FOR THE DETECTION OF GLYCOSAMINOGLYCANES |
| CN102796723A (zh) * | 2012-09-11 | 2012-11-28 | 深圳市海普瑞药业股份有限公司 | 肝素酶i的固定化方法 |
| CN102888390B (zh) * | 2012-10-30 | 2014-09-03 | 深圳市海普瑞药业股份有限公司 | 肝素酶ⅲ的固定化方法 |
| CN103059165B (zh) * | 2012-12-26 | 2015-04-29 | 安徽丰原药业股份有限公司 | 一种多糖酰化物及其制备方法 |
| JP6225321B1 (ja) | 2016-08-31 | 2017-11-08 | 王子ホールディングス株式会社 | ポリ硫酸ペントサンの製造方法 |
| WO2018043666A1 (ja) | 2016-08-31 | 2018-03-08 | 王子ホールディングス株式会社 | 酸性キシロオリゴ糖の製造方法 |
| JP6281659B1 (ja) | 2017-02-28 | 2018-02-21 | 王子ホールディングス株式会社 | ポリ硫酸ペントサン、医薬組成物及び抗凝固剤 |
| EP3632451A4 (en) | 2017-05-31 | 2021-03-10 | Oji Holdings Corporation | MOISTURIZING TOPICAL PREPARATION |
| WO2019054344A1 (ja) | 2017-09-12 | 2019-03-21 | 王子ホールディングス株式会社 | ポリ硫酸ペントサン及びポリ硫酸ペントサンの製造方法 |
| AU2018387999B2 (en) | 2017-12-20 | 2021-06-17 | Oji Holdings Corporation | Pentosan polysulfate and medicine containing pentosan polysulfate |
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| US6162797A (en) * | 1996-05-10 | 2000-12-19 | Inalco S.P.A. | Derivatives of K5 polysaccharide having high anticoagulant activity |
| WO2001072848A1 (en) * | 2000-03-30 | 2001-10-04 | Inalco S.P.A. | Glycosaminoglycans derived from the k5 polysaccharide having high anticoagulant and antithrombotic activity and process for their preparation |
| JP2001518133A (ja) * | 1997-03-24 | 2001-10-09 | イナルコ ソシエタ ペル アチオニ | 高い抗血栓症活性を有するグリコサミノグリカン類 |
| WO2002050125A2 (en) * | 2000-12-18 | 2002-06-27 | Pasqua Oreste | Glycosaminoglycans derived from k5 polysaccharide having high antithrombin activity and process for their preparation |
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| IT1214609B (it) * | 1985-05-17 | 1990-01-18 | Opocrin Spa | Esosaminoglicani solfati depolimerizzati ad attivita'antitrombotica, fibrinolitica, antinfiammatoria, loro procedimento di preparazione e composizioni farmaceutiche che li contengono. |
| FR2669932B1 (fr) | 1990-12-03 | 1994-07-01 | Sanofi Sa | Nouvel heparosane-n,o-sulfate, son procede de preparation et les compositions pharmaceutiques qui le contiennent. |
| IT1271057B (it) | 1994-11-04 | 1997-05-26 | Inalco Spa | Polisaccaridi aventi un elevato contenuto di acido iduronico |
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| PL375088A1 (en) * | 2002-06-18 | 2005-11-14 | Glycores 2000 S.R.L. | Epimerized derivatives of k5 polysaccharide with a very high degree of sulfation |
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2003
- 2003-08-06 IT IT001618A patent/ITMI20031618A1/it unknown
-
2004
- 2004-07-07 CA CA002534709A patent/CA2534709A1/en not_active Abandoned
- 2004-07-07 WO PCT/EP2004/051391 patent/WO2005014656A1/en not_active Ceased
- 2004-07-07 EP EP04766148A patent/EP1654288B9/en not_active Expired - Lifetime
- 2004-07-07 MX MXPA06001511A patent/MXPA06001511A/es active IP Right Grant
- 2004-07-07 ES ES04766148T patent/ES2341249T3/es not_active Expired - Lifetime
- 2004-07-07 RU RU2006106790/04A patent/RU2361881C2/ru not_active IP Right Cessation
- 2004-07-07 JP JP2006522341A patent/JP2007501305A/ja active Pending
- 2004-07-07 AT AT04766148T patent/ATE458009T1/de not_active IP Right Cessation
- 2004-07-07 DE DE602004025583T patent/DE602004025583D1/de not_active Expired - Fee Related
- 2004-07-07 US US10/557,584 patent/US7687249B2/en not_active Expired - Fee Related
- 2004-07-07 CN CNA2004800223076A patent/CN1832966A/zh active Pending
- 2004-07-07 BR BRPI0413346-3A patent/BRPI0413346A/pt not_active IP Right Cessation
- 2004-07-07 KR KR1020067002532A patent/KR20060063933A/ko not_active Withdrawn
- 2004-07-07 AU AU2004262584A patent/AU2004262584A1/en not_active Abandoned
- 2004-07-07 DK DK04766148.3T patent/DK1654288T3/da active
-
2006
- 2006-01-31 IL IL173482A patent/IL173482A0/en unknown
- 2006-02-24 ZA ZA200601643A patent/ZA200601643B/en unknown
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| US6162797A (en) * | 1996-05-10 | 2000-12-19 | Inalco S.P.A. | Derivatives of K5 polysaccharide having high anticoagulant activity |
| JP2001518133A (ja) * | 1997-03-24 | 2001-10-09 | イナルコ ソシエタ ペル アチオニ | 高い抗血栓症活性を有するグリコサミノグリカン類 |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013503606A (ja) * | 2009-09-01 | 2013-02-04 | レンセラー ポリテクニック インスティチュート | Ｋ５ヘパロサン発酵および精製 |
| WO2017115674A1 (ja) * | 2015-12-28 | 2017-07-06 | 味の素株式会社 | 抗凝固活性を有するヘパラン硫酸の製造法 |
| JPWO2017115674A1 (ja) * | 2015-12-28 | 2018-10-18 | 味の素株式会社 | 抗凝固活性を有するヘパラン硫酸の製造法 |
| US10704068B2 (en) | 2015-12-28 | 2020-07-07 | Ajinomoto Co., Inc. | Method of producing heparan sulfate having anticoagulant activity |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1654288B1 (en) | 2010-02-17 |
| ES2341249T3 (es) | 2010-06-17 |
| AU2004262584A1 (en) | 2005-02-17 |
| CN1832966A (zh) | 2006-09-13 |
| WO2005014656A1 (en) | 2005-02-17 |
| EP1654288B9 (en) | 2010-06-23 |
| RU2361881C2 (ru) | 2009-07-20 |
| DK1654288T3 (da) | 2010-09-20 |
| DE602004025583D1 (de) | 2010-04-01 |
| EP1654288A1 (en) | 2006-05-10 |
| KR20060063933A (ko) | 2006-06-12 |
| ZA200601643B (en) | 2007-05-30 |
| ATE458009T1 (de) | 2010-03-15 |
| ITMI20031618A1 (it) | 2005-02-07 |
| US7687249B2 (en) | 2010-03-30 |
| US20070042993A1 (en) | 2007-02-22 |
| RU2006106790A (ru) | 2007-09-20 |
| IL173482A0 (en) | 2006-06-11 |
| CA2534709A1 (en) | 2005-02-17 |
| MXPA06001511A (es) | 2006-05-15 |
| BRPI0413346A (pt) | 2006-10-10 |
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