JP2007500210A5 - - Google Patents
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- Publication number
- JP2007500210A5 JP2007500210A5 JP2006532392A JP2006532392A JP2007500210A5 JP 2007500210 A5 JP2007500210 A5 JP 2007500210A5 JP 2006532392 A JP2006532392 A JP 2006532392A JP 2006532392 A JP2006532392 A JP 2006532392A JP 2007500210 A5 JP2007500210 A5 JP 2007500210A5
- Authority
- JP
- Japan
- Prior art keywords
- amine
- substituted
- irm
- ether
- tetrahydroimidazoquinoline
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- -1 IRM compound Chemical class 0.000 claims 31
- RTZKZFJDLAIYFH-UHFFFAOYSA-N ether Substances CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims 15
- 229940124669 imidazoquinoline Drugs 0.000 claims 11
- 239000004202 carbamide Substances 0.000 claims 6
- 229940124530 sulfonamide Drugs 0.000 claims 6
- XSQUKJJJFZCRTK-UHFFFAOYSA-N urea group Chemical group NC(=O)N XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims 6
- 239000012876 carrier material Substances 0.000 claims 5
- 150000001408 amides Chemical group 0.000 claims 3
- 125000005013 aryl ether group Chemical group 0.000 claims 3
- 150000003456 sulfonamides Chemical group 0.000 claims 3
- 125000000101 thioether group Chemical group 0.000 claims 3
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 239000002245 particle Substances 0.000 claims 2
- QWTGJQJILBSXEC-UHFFFAOYSA-N 1,2,3,4-tetrahydro-1,8-naphthyridin-2-amine Chemical compound C1=CN=C2NC(N)CCC2=C1 QWTGJQJILBSXEC-UHFFFAOYSA-N 0.000 claims 1
- XGKHUHWWPFOKMN-UHFFFAOYSA-N 1,2,3,4-tetrahydroquinolin-2-amine Chemical compound C1=CC=C2NC(N)CCC2=C1 XGKHUHWWPFOKMN-UHFFFAOYSA-N 0.000 claims 1
- GCMNJUJAKQGROZ-UHFFFAOYSA-N 1,2-Dihydroquinolin-2-imine Chemical compound C1=CC=CC2=NC(N)=CC=C21 GCMNJUJAKQGROZ-UHFFFAOYSA-N 0.000 claims 1
- JWLAFIOGOBJKEP-UHFFFAOYSA-N 1h-imidazo[4,5-b][1,8]naphthyridin-2-amine Chemical compound C1=CN=C2NC3=NC(N)=NC3=CC2=C1 JWLAFIOGOBJKEP-UHFFFAOYSA-N 0.000 claims 1
- VIIYMKOWLFKDHA-UHFFFAOYSA-N 2,3,3a,4-tetrahydro-1h-imidazo[4,5-b][1,8]naphthyridin-2-amine Chemical compound N1C2=NC=CC=C2C=C2C1NC(N)N2 VIIYMKOWLFKDHA-UHFFFAOYSA-N 0.000 claims 1
- GCGNWZMOENODOJ-UHFFFAOYSA-N 2,3,3a,4-tetrahydro-1h-imidazo[4,5-h]quinoline Chemical class C1C=C2C=CC=NC2=C2C1NCN2 GCGNWZMOENODOJ-UHFFFAOYSA-N 0.000 claims 1
- ICSNLGPSRYBMBD-UHFFFAOYSA-N 2-aminopyridine Chemical compound NC1=CC=CC=N1 ICSNLGPSRYBMBD-UHFFFAOYSA-N 0.000 claims 1
- WSIZDLIFQIDDKA-UHFFFAOYSA-N 3h-imidazo[4,5-h]quinolin-2-amine Chemical compound C1=CC=NC2=C(NC(N)=N3)C3=CC=C21 WSIZDLIFQIDDKA-UHFFFAOYSA-N 0.000 claims 1
- QOOXNMYDCWUEHW-UHFFFAOYSA-N [1,3]oxazolo[4,5-h]quinolin-2-amine Chemical compound C1=CC=NC2=C(OC(N)=N3)C3=CC=C21 QOOXNMYDCWUEHW-UHFFFAOYSA-N 0.000 claims 1
- YUDGNSDTJOJYBS-UHFFFAOYSA-N [1,3]oxazolo[5,4-b][1,8]naphthyridin-2-amine Chemical compound C1=CN=C2N=C(OC(N)=N3)C3=CC2=C1 YUDGNSDTJOJYBS-UHFFFAOYSA-N 0.000 claims 1
- YSQNOJMVGVZJRJ-UHFFFAOYSA-N [1,3]oxazolo[5,4-b]pyridin-2-amine Chemical compound C1=CN=C2OC(N)=NC2=C1 YSQNOJMVGVZJRJ-UHFFFAOYSA-N 0.000 claims 1
- SQQXRXKYTKFFSM-UHFFFAOYSA-N chembl1992147 Chemical class OC1=C(OC)C(OC)=CC=C1C1=C(C)C(C(O)=O)=NC(C=2N=C3C4=NC(C)(C)N=C4C(OC)=C(O)C3=CC=2)=C1N SQQXRXKYTKFFSM-UHFFFAOYSA-N 0.000 claims 1
- 239000000539 dimer Substances 0.000 claims 1
- 125000001072 heteroaryl group Chemical group 0.000 claims 1
- 229920000592 inorganic polymer Polymers 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 239000002184 metal Substances 0.000 claims 1
- 229920000620 organic polymer Polymers 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46214003P | 2003-04-10 | 2003-04-10 | |
| US10/640,904 US7427629B2 (en) | 2002-08-15 | 2003-08-14 | Immunostimulatory compositions and methods of stimulating an immune response |
| US51525603P | 2003-10-29 | 2003-10-29 | |
| US54554204P | 2004-02-18 | 2004-02-18 | |
| US54542404P | 2004-02-18 | 2004-02-18 | |
| PCT/US2004/011081 WO2004108072A2 (en) | 2003-04-10 | 2004-04-09 | Delivery of immune response modifier compounds using metal-containing particulate support materials |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007500210A JP2007500210A (ja) | 2007-01-11 |
| JP2007500210A5 true JP2007500210A5 (https=) | 2007-05-31 |
Family
ID=33136302
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006532392A Withdrawn JP2007500210A (ja) | 2003-04-10 | 2004-04-09 | 金属含有微粒子担体材料を使用した免疫反応調節物質化合物の送達 |
| JP2006509884A Ceased JP2006522823A (ja) | 2003-04-10 | 2004-04-09 | 免疫反応調節物質化合物の送達 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006509884A Ceased JP2006522823A (ja) | 2003-04-10 | 2004-04-09 | 免疫反応調節物質化合物の送達 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20040202720A1 (https=) |
| EP (2) | EP1615665A4 (https=) |
| JP (2) | JP2007500210A (https=) |
| AU (2) | AU2004244962A1 (https=) |
| CA (1) | CA2521682A1 (https=) |
| WO (2) | WO2004108072A2 (https=) |
Families Citing this family (128)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA67760C2 (uk) | 1997-12-11 | 2004-07-15 | Міннесота Майнінг Енд Мануфакчурінг Компані | Імідазонафтиридин та тетрагідроімідазонафтиридин, фармацевтична композиція, спосіб індукування біосинтезу цитокінів та спосіб лікування вірусної інфекції, проміжні сполуки |
| US6756382B2 (en) * | 1999-06-10 | 2004-06-29 | 3M Innovative Properties Company | Amide substituted imidazoquinolines |
| US6331539B1 (en) * | 1999-06-10 | 2001-12-18 | 3M Innovative Properties Company | Sulfonamide and sulfamide substituted imidazoquinolines |
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| US20060142202A1 (en) * | 2000-12-08 | 2006-06-29 | 3M Innovative Properties Company | Compositions and methods for targeted delivery of immune response modifiers |
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| NZ534566A (en) * | 2002-02-22 | 2007-02-23 | 3M Innovative Properties Co | Method of reducing and treating UVB-induced immunosuppression |
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| JP2007530450A (ja) * | 2003-12-29 | 2007-11-01 | スリーエム イノベイティブ プロパティズ カンパニー | ピペラジン、［１，４］ジアゼパン、［１，４］ジアゾカン、および［１，５］ジアゾカン縮合イミダゾ環化合物 |
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2004
- 2004-04-09 AU AU2004244962A patent/AU2004244962A1/en not_active Abandoned
- 2004-04-09 JP JP2006532392A patent/JP2007500210A/ja not_active Withdrawn
- 2004-04-09 EP EP04749964A patent/EP1615665A4/en not_active Withdrawn
- 2004-04-09 WO PCT/US2004/011081 patent/WO2004108072A2/en not_active Ceased
- 2004-04-09 US US10/821,319 patent/US20040202720A1/en not_active Abandoned
- 2004-04-09 EP EP04775876A patent/EP1617871A4/en not_active Withdrawn
- 2004-04-09 WO PCT/US2004/011062 patent/WO2004091500A2/en not_active Ceased
- 2004-04-09 US US10/821,335 patent/US7923560B2/en not_active Expired - Fee Related
- 2004-04-09 JP JP2006509884A patent/JP2006522823A/ja not_active Ceased
- 2004-04-09 CA CA002521682A patent/CA2521682A1/en not_active Abandoned
- 2004-04-09 AU AU2004229478A patent/AU2004229478B2/en not_active Ceased
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