JP2007326877A5 - - Google Patents
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- Publication number
- JP2007326877A5 JP2007326877A5 JP2007229798A JP2007229798A JP2007326877A5 JP 2007326877 A5 JP2007326877 A5 JP 2007326877A5 JP 2007229798 A JP2007229798 A JP 2007229798A JP 2007229798 A JP2007229798 A JP 2007229798A JP 2007326877 A5 JP2007326877 A5 JP 2007326877A5
- Authority
- JP
- Japan
- Prior art keywords
- weight
- liposome
- parts
- cysteinyl
- glutamyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000002502 liposome Substances 0.000 claims 17
- 238000002360 preparation method Methods 0.000 claims 9
- 238000009472 formulation Methods 0.000 claims 8
- 239000000203 mixture Substances 0.000 claims 8
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims 6
- ATBOMIWRCZXYSZ-XZBBILGWSA-N [1-[2,3-dihydroxypropoxy(hydroxy)phosphoryl]oxy-3-hexadecanoyloxypropan-2-yl] (9e,12e)-octadeca-9,12-dienoate Chemical compound CCCCCCCCCCCCCCCC(=O)OCC(COP(O)(=O)OCC(O)CO)OC(=O)CCCCCCC\C=C\C\C=C\CCCCC ATBOMIWRCZXYSZ-XZBBILGWSA-N 0.000 claims 6
- AWUCVROLDVIAJX-UHFFFAOYSA-N alpha-glycerophosphate Natural products OCC(O)COP(O)(O)=O AWUCVROLDVIAJX-UHFFFAOYSA-N 0.000 claims 6
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims 6
- 150000001875 compounds Chemical class 0.000 claims 6
- 238000000034 method Methods 0.000 claims 6
- WTJKGGKOPKCXLL-RRHRGVEJSA-N phosphatidylcholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC WTJKGGKOPKCXLL-RRHRGVEJSA-N 0.000 claims 6
- 150000003839 salts Chemical class 0.000 claims 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 4
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims 4
- 229930006000 Sucrose Natural products 0.000 claims 4
- 150000002632 lipids Chemical class 0.000 claims 4
- 239000005720 sucrose Substances 0.000 claims 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 4
- 238000004519 manufacturing process Methods 0.000 claims 2
- 238000002512 chemotherapy Methods 0.000 claims 1
- 239000000470 constituent Substances 0.000 claims 1
- 230000001066 destructive effect Effects 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 238000004108 freeze drying Methods 0.000 claims 1
- 230000011132 hemopoiesis Effects 0.000 claims 1
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23853099A | 1999-01-27 | 1999-01-27 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000595670A Division JP2002535359A (ja) | 1999-01-27 | 2000-01-27 | グルタチオン類縁体を含有する治療用組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007326877A JP2007326877A (ja) | 2007-12-20 |
| JP2007326877A5 true JP2007326877A5 (enExample) | 2010-09-30 |
Family
ID=22898312
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000595670A Pending JP2002535359A (ja) | 1999-01-27 | 2000-01-27 | グルタチオン類縁体を含有する治療用組成物 |
| JP2007229798A Pending JP2007326877A (ja) | 1999-01-27 | 2007-09-05 | グルタチオン類縁体を含有する治療用組成物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000595670A Pending JP2002535359A (ja) | 1999-01-27 | 2000-01-27 | グルタチオン類縁体を含有する治療用組成物 |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP1143992B1 (enExample) |
| JP (2) | JP2002535359A (enExample) |
| KR (1) | KR100750842B1 (enExample) |
| CN (1) | CN1185008C (enExample) |
| AT (1) | ATE286741T1 (enExample) |
| AU (1) | AU778340B2 (enExample) |
| CA (1) | CA2360795C (enExample) |
| DE (1) | DE60017359T2 (enExample) |
| ES (1) | ES2231159T3 (enExample) |
| HK (1) | HK1043310B (enExample) |
| PT (1) | PT1143992E (enExample) |
| WO (1) | WO2000044366A2 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6627732B1 (en) | 1998-04-16 | 2003-09-30 | Teijin Limited | Glutathione derivatives and their dosage forms |
| US7029695B2 (en) | 2001-07-10 | 2006-04-18 | Telik, Inc. | Therapeutic compositions containing glutathione analogs |
| CN101090977B (zh) | 2005-01-06 | 2013-04-10 | 泰立克公司 | 三肽和四肽硫醚 |
| CN101434645B (zh) * | 2008-12-24 | 2013-01-16 | 中国农业大学 | 一种合成寡肽及其用途 |
| EP2785689A1 (en) * | 2011-12-02 | 2014-10-08 | Telik, Inc. | Amorphous ezatiostat ansolvate |
| CN108863888B (zh) * | 2018-07-18 | 2021-10-12 | 吉尔生化（上海）有限公司 | 一种(s)-1-(叔丁氧羰基)-5-氧吡咯烷-2-羧酸乙酯的制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5786336A (en) * | 1991-04-29 | 1998-07-28 | Terrapin Technologies, Inc. | Target-selective protocols based on mimics |
| JP3118869B2 (ja) * | 1991-05-14 | 2000-12-18 | ウェルファイド株式会社 | プロスタグランジン類含有脂肪小体組成物 |
| CA2087902C (en) * | 1992-02-05 | 2006-10-17 | Narendra Raghunathji Desai | Liposome compositions of porphyrin photosensitizers |
| JP3383704B2 (ja) * | 1993-04-02 | 2003-03-04 | わかもと製薬株式会社 | 安定なリポソーム水分散液 |
| EP0721328A4 (en) * | 1993-09-27 | 1997-09-17 | Smithkline Beecham Corp | CAMPTOTHECIN FORMULATIONS |
| JP2891883B2 (ja) * | 1993-11-05 | 1999-05-17 | 学校法人近畿大学 | 抗白内障医薬組成物 |
| JPH11507056A (ja) * | 1995-06-07 | 1999-06-22 | テラピン テクノロジーズ、インク． | グルタチオンアナログの代謝的効果 |
-
2000
- 2000-01-27 PT PT00908420T patent/PT1143992E/pt unknown
- 2000-01-27 ES ES00908420T patent/ES2231159T3/es not_active Expired - Lifetime
- 2000-01-27 HK HK02104871.4A patent/HK1043310B/zh not_active IP Right Cessation
- 2000-01-27 WO PCT/US2000/002297 patent/WO2000044366A2/en not_active Ceased
- 2000-01-27 AT AT00908420T patent/ATE286741T1/de active
- 2000-01-27 CA CA2360795A patent/CA2360795C/en not_active Expired - Fee Related
- 2000-01-27 DE DE60017359T patent/DE60017359T2/de not_active Expired - Lifetime
- 2000-01-27 EP EP00908420A patent/EP1143992B1/en not_active Expired - Lifetime
- 2000-01-27 KR KR1020017009543A patent/KR100750842B1/ko not_active Expired - Fee Related
- 2000-01-27 JP JP2000595670A patent/JP2002535359A/ja active Pending
- 2000-01-27 CN CNB008046522A patent/CN1185008C/zh not_active Expired - Fee Related
- 2000-01-27 AU AU29767/00A patent/AU778340B2/en not_active Ceased
-
2007
- 2007-09-05 JP JP2007229798A patent/JP2007326877A/ja active Pending
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