|
US3536809A
(en)
|
1969-02-17 |
1970-10-27 |
Alza Corp |
Medication method
|
|
US3598123A
(en)
|
1969-04-01 |
1971-08-10 |
Alza Corp |
Bandage for administering drugs
|
|
BE757436A
(fr)
*
|
1969-10-27 |
1971-03-16 |
Robins Co Inc A H |
1-carbamoyl-4-phenyl-piperidines et -tetrahydropyridines, leur procede de preparation et leurs applications comme anticonvulsivants et relaxants musculaires
|
|
US3845770A
(en)
|
1972-06-05 |
1974-11-05 |
Alza Corp |
Osmatic dispensing device for releasing beneficial agent
|
|
US3916899A
(en)
|
1973-04-25 |
1975-11-04 |
Alza Corp |
Osmotic dispensing device with maximum and minimum sizes for the passageway
|
|
US4008719A
(en)
|
1976-02-02 |
1977-02-22 |
Alza Corporation |
Osmotic system having laminar arrangement for programming delivery of active agent
|
|
IE58110B1
(en)
|
1984-10-30 |
1993-07-14 |
Elan Corp Plc |
Controlled release powder and process for its preparation
|
|
DE3440141A1
(de)
|
1984-11-02 |
1986-05-07 |
Heiner Dipl.-Chem. Dr. 8000 München Eckert |
Verwendung von kohlensaeure-bis-trichlormethylester als proreagens fuer phosgen
|
|
JPH0680054B2
(ja)
|
1985-06-19 |
1994-10-12 |
吉富製薬株式会社 |
ピペリジン誘導体
|
|
US5316759A
(en)
|
1986-03-17 |
1994-05-31 |
Robert J. Schaap |
Agonist-antagonist combination to reduce the use of nicotine and other drugs
|
|
US4797419A
(en)
*
|
1986-11-03 |
1989-01-10 |
Warner-Lambert Company |
Method of treating the symptoms of senile cognitive decline employing di- or trisubstituted urea cholinergic agents
|
|
US5198459A
(en)
|
1987-07-11 |
1993-03-30 |
Sandoz Ltd. |
Use of 5HT-3 antagonists in preventing or reducing dependency on dependency-inducing agents
|
|
DE3822792C2
(de)
|
1987-07-11 |
1997-11-27 |
Sandoz Ag |
Neue Verwendung von 5HT¶3¶-Antagonisten
|
|
US5506191A
(en)
|
1987-11-02 |
1996-04-09 |
Sandoz Ltd. |
Heterocyclic hydrazines and hydrazones
|
|
US5073543A
(en)
|
1988-07-21 |
1991-12-17 |
G. D. Searle & Co. |
Controlled release formulations of trophic factors in ganglioside-lipsome vehicle
|
|
IT1229203B
(it)
|
1989-03-22 |
1991-07-25 |
Bioresearch Spa |
Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative.
|
|
US5120548A
(en)
|
1989-11-07 |
1992-06-09 |
Merck & Co., Inc. |
Swelling modulated polymeric drug delivery device
|
|
US5075341A
(en)
|
1989-12-01 |
1991-12-24 |
The Mclean Hospital Corporation |
Treatment for cocaine abuse
|
|
US5733566A
(en)
|
1990-05-15 |
1998-03-31 |
Alkermes Controlled Therapeutics Inc. Ii |
Controlled release of antiparasitic agents in animals
|
|
US5698155A
(en)
|
1991-05-31 |
1997-12-16 |
Gs Technologies, Inc. |
Method for the manufacture of pharmaceutical cellulose capsules
|
|
US6204284B1
(en)
|
1991-12-20 |
2001-03-20 |
American Cyanamid Company |
Use of 1-(substitutedphenyl)-3-azabicyclo[3.1.0]hexanes for the treatment of chemical dependencies
|
|
US5580578A
(en)
|
1992-01-27 |
1996-12-03 |
Euro-Celtique, S.A. |
Controlled release formulations coated with aqueous dispersions of acrylic polymers
|
|
US5232934A
(en)
|
1992-07-17 |
1993-08-03 |
Warner-Lambert Co. |
Method for the treatment of psychomotor stimulant addiction
|
|
DE4234295A1
(de)
*
|
1992-10-12 |
1994-04-14 |
Thomae Gmbh Dr K |
Carbonsäurederivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
|
|
US5591767A
(en)
|
1993-01-25 |
1997-01-07 |
Pharmetrix Corporation |
Liquid reservoir transdermal patch for the administration of ketorolac
|
|
US5321012A
(en)
|
1993-01-28 |
1994-06-14 |
Virginia Commonwealth University Medical College |
Inhibiting the development of tolerance to and/or dependence on a narcotic addictive substance
|
|
IT1270594B
(it)
|
1994-07-07 |
1997-05-07 |
Recordati Chem Pharm |
Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida
|
|
US5556837A
(en)
|
1994-08-01 |
1996-09-17 |
Regeneron Pharmaceuticals Inc. |
Methods for treating addictive disorders
|
|
US5762925A
(en)
|
1994-11-03 |
1998-06-09 |
Sagen; Jacqueline |
Preventing opiate tolerance by cellular implantation
|
|
ES2247604T3
(es)
|
1995-06-12 |
2006-03-01 |
G.D. SEARLE & CO. |
Composiciones que comprenden un inhibidor de ciclooxigenasa-2 y un inhibidor de 5-lipoxigenasa.
|
|
TR199800409T1
(xx)
|
1995-09-07 |
1998-05-21 |
F.Hoffmann-La Roche Ag |
Kalp ve b�brek yetersizli�inin tedavii�in yeni 4-(oksialkoksifenil)-3-oksi-piperidinler
|
|
FR2740134B1
(fr)
|
1995-10-18 |
1998-01-09 |
Pf Medicament |
Derives d'amines cycliques d'aryl-piperazines, leur preparation et les compositions pharmaceutiques les contenant
|
|
FR2744448B1
(fr)
*
|
1996-02-02 |
1998-04-24 |
Pf Medicament |
Nouvelles piperidines derivees d'aryl piperazine, ainsi que leur procede de preparation, les compositions pharmaceutiques et leur utilisation comme medicaments
|
|
CA2274593A1
(en)
|
1996-12-13 |
1998-06-18 |
Banyu Pharmaceutical Co., Ltd. |
Novel aminopyrazole derivatives
|
|
FR2758328B1
(fr)
*
|
1997-01-15 |
1999-04-02 |
Pf Medicament |
Nouvelles amines aromatiques derivees d'amines cycliques utiles comme medicaments
|
|
WO1999009140A1
(en)
|
1997-08-20 |
1999-02-25 |
The Regents Of The University Of California |
Nucleic acid sequences encoding capsaicin receptor and capsaicin receptor-related polypeptides and uses thereof
|
|
EP0943683A1
(en)
|
1998-03-10 |
1999-09-22 |
Smithkline Beecham Plc |
Human vanilloid receptor homologue Vanilrep1
|
|
AU4685699A
(en)
|
1998-06-19 |
2000-01-05 |
Eli Lilly And Company |
Preparation of heteroaryl compounds
|
|
ES2151828B1
(es)
|
1998-07-10 |
2001-08-16 |
Esteve Labor Dr |
Empleo de derivados de tetrahidropiridinas (ohidroxi-piperidinas)-b utilazoles en la elaboracion de un medicamento para el tratamiento del dolor.
|
|
CN1129581C
(zh)
|
1998-09-22 |
2003-12-03 |
山之内制药株式会社 |
氰基苯基衍生物
|
|
SE9803773D0
(sv)
|
1998-11-05 |
1998-11-05 |
Astra Pharma Prod |
Compounds
|
|
CA2358095A1
(en)
|
1998-12-23 |
2000-07-06 |
Eli Lilly And Company |
Heteroroaromatic amides as inhibitor of factor xa
|
|
AU3215500A
(en)
|
1999-01-25 |
2000-08-07 |
Smithkline Beecham Corporation |
Compounds and methods
|
|
GB9907097D0
(en)
|
1999-03-26 |
1999-05-19 |
Novartis Ag |
Organic compounds
|
|
EP1183238A1
(en)
*
|
1999-05-17 |
2002-03-06 |
Eli Lilly And Company |
Metabotropic glutamate receptor antagonists
|
|
AU7514700A
(en)
*
|
1999-09-07 |
2001-04-10 |
Syngenta Participations Ag |
Cyanopiperidines
|
|
ATE402704T1
(de)
|
2000-03-27 |
2008-08-15 |
Abbott Gmbh & Co Kg |
Dopamin-d3-rezeptor-liganden zur behandlung von sucht
|
|
EP1285651B1
(en)
|
2000-04-28 |
2010-09-01 |
Takeda Pharmaceutical Company Limited |
Melanin concentrating hormone antagonists
|
|
OA12274A
(en)
|
2000-05-22 |
2006-05-09 |
Aventis Pharma Inc |
Arylmethylamine derivatives for use as tryptase inhibitors.
|
|
AU2001281817B2
(en)
|
2000-06-21 |
2005-11-24 |
F. Hoffmann-La Roche Ag |
Benzothiazole derivatives
|
|
AU2001280599A1
(en)
|
2000-07-15 |
2002-01-30 |
Smith Kline Beecham Corporation |
Compounds and methods
|
|
EP1301484A2
(en)
|
2000-07-20 |
2003-04-16 |
Neurogen Corporation |
Capsaicin receptor ligands
|
|
US20040259912A1
(en)
|
2001-09-28 |
2004-12-23 |
Takahiro Matsumoto |
Benzine derivatives, process for preparing the same and use thereof
|
|
WO2003053922A2
(en)
*
|
2001-12-19 |
2003-07-03 |
Merck & Co., Inc. |
Heteroaryl substituted imidazole modulators of metabotropic glutamate receptor-5
|
|
US7390813B1
(en)
|
2001-12-21 |
2008-06-24 |
Xenon Pharmaceuticals Inc. |
Pyridylpiperazines and aminonicotinamides and their use as therapeutic agents
|
|
US7071335B2
(en)
|
2002-02-01 |
2006-07-04 |
Euro-Celtique S.A. |
2-pyridinyl-1-piperazine therapeutic agents useful for treating pain
|
|
AU2003245773A1
(en)
|
2002-02-15 |
2003-09-04 |
Glaxo Group Limited |
Vanilloid receptor modulators
|
|
US6974818B2
(en)
|
2002-03-01 |
2005-12-13 |
Euro-Celtique S.A. |
1,2,5-thiadiazol-3-YL-piperazine therapeutic agents useful for treating pain
|
|
GB0209715D0
(en)
|
2002-04-27 |
2002-06-05 |
Astrazeneca Ab |
Chemical compounds
|
|
WO2003099266A2
(en)
|
2002-05-23 |
2003-12-04 |
Abbott Laboratories |
Acetamides and benzamides that are useful in treating sexual dysfunction
|
|
US20030232836A1
(en)
|
2002-05-23 |
2003-12-18 |
Stewart Andrew O. |
Acetamides and benzamides that are useful in treating sexual dysfunction
|
|
JPWO2004002531A1
(ja)
|
2002-06-26 |
2005-10-27 |
小野薬品工業株式会社 |
血管の収縮または拡張による疾患治療剤
|
|
EA200500114A1
(ru)
|
2002-06-28 |
2005-06-30 |
Еуро-Селтик, С. А. |
Терапевтические агенты, используемые для лечения боли
|
|
US7262194B2
(en)
|
2002-07-26 |
2007-08-28 |
Euro-Celtique S.A. |
Therapeutic agents useful for treating pain
|
|
US7157462B2
(en)
|
2002-09-24 |
2007-01-02 |
Euro-Celtique S.A. |
Therapeutic agents useful for treating pain
|
|
DE10252666A1
(de)
|
2002-11-11 |
2004-08-05 |
Grünenthal GmbH |
N-Piperidyl-cyclohexan-Derivate
|
|
US7582635B2
(en)
*
|
2002-12-24 |
2009-09-01 |
Purdue Pharma, L.P. |
Therapeutic agents useful for treating pain
|
|
US7223788B2
(en)
|
2003-02-14 |
2007-05-29 |
Sanofi-Aventis Deutschland Gmbh |
Substituted N-aryl heterocycles, process for their preparation and their use as medicaments
|
|
DE10306250A1
(de)
*
|
2003-02-14 |
2004-09-09 |
Aventis Pharma Deutschland Gmbh |
Substituierte N-Arylheterozyklen, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
|
US7067509B2
(en)
|
2003-03-07 |
2006-06-27 |
Neurocrine Biosciences, Inc. |
Melanin-concentrating hormone receptor antagonists and compositions and methods related thereto
|
|
DE10311065A1
(de)
|
2003-03-13 |
2004-09-23 |
Abbott Gmbh & Co. Kg |
Pyrimidin-2-on-Verbindungen und ihre therapeutische Verwendung
|
|
CN1780836A
(zh)
|
2003-04-28 |
2006-05-31 |
埃科特莱茵药品有限公司 |
作为血管紧张肽原酶抑制剂的新型二氮杂双环壬烯和四氢吡啶衍生物
|
|
EP1627869B1
(en)
|
2003-05-20 |
2012-05-02 |
Ajinomoto Co., Inc. |
Vanilloid receptor modulators
|
|
TWI287010B
(en)
|
2003-06-12 |
2007-09-21 |
Euro Celtique Sa |
Therapeutic agents useful for treating pain
|
|
US20050009841A1
(en)
|
2003-07-11 |
2005-01-13 |
Zheng Guo Zhu |
Novel amides useful for treating pain
|
|
US7129235B2
(en)
|
2003-07-11 |
2006-10-31 |
Abbott Laboratories |
Amides useful for treating pain
|
|
GEP20094676B
(en)
|
2003-07-24 |
2009-05-10 |
Euro Celtique Sa |
Piperidine compounds and pharmaceutical compositions containing them
|
|
DE602004017316D1
(de)
|
2003-07-24 |
2008-12-04 |
Euro Celtique Sa |
Heteroaryl-tetrahydropyridylverbindungen, die sich für die behandlung bzw. die prävention von schmerzen eignen
|
|
MXPA06001202A
(es)
|
2003-07-29 |
2006-08-31 |
Xenon Pharmaceuticals Inc |
Derivados piridilo y su uso como agentes terapeuticos.
|
|
US7456180B2
(en)
|
2003-07-30 |
2008-11-25 |
Xenon Pharmaceuticals Inc. |
Piperazine derivatives and their use as therapeutic agents
|
|
CA2533897A1
(en)
|
2003-07-30 |
2005-02-10 |
Xenon Pharmaceuticals Inc. |
Pyridazine derivatives and their use as therapeutic agents
|
|
WO2005012287A1
(en)
|
2003-08-01 |
2005-02-10 |
Euro-Celtique S.A. |
Therapeutic agents useful for treating pain
|
|
PL1664041T3
(pl)
|
2003-09-22 |
2008-12-31 |
Euro Celtique Sa |
Przydatne do leczenia bólu związki fenylowo-karboksyamidowe
|
|
EP1680431A1
(en)
|
2003-10-17 |
2006-07-19 |
Rigel Pharmaceuticals, Inc. |
Benzothiazole and thiazole'5,5-b!pyridine compositions and their use as ubiquitin ligase inhibitors
|
|
NZ590160A
(en)
|
2003-11-21 |
2012-07-27 |
Array Biopharma Inc |
AKT protein kinase inhibitors
|