JP2006523233A5 - - Google Patents
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- Publication number
- JP2006523233A5 JP2006523233A5 JP2006509369A JP2006509369A JP2006523233A5 JP 2006523233 A5 JP2006523233 A5 JP 2006523233A5 JP 2006509369 A JP2006509369 A JP 2006509369A JP 2006509369 A JP2006509369 A JP 2006509369A JP 2006523233 A5 JP2006523233 A5 JP 2006523233A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- aryl
- hydrogen
- substituted
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 CNCC(****)=O Chemical compound CNCC(****)=O 0.000 description 3
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45882703P | 2003-03-28 | 2003-03-28 | |
| US60/458,827 | 2003-03-28 | ||
| US49616503P | 2003-08-19 | 2003-08-19 | |
| US60/496,165 | 2003-08-19 | ||
| PCT/US2004/009380 WO2004087672A1 (en) | 2003-03-28 | 2004-03-26 | Migrastatin analog compositions and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011039073A Division JP2011105766A (ja) | 2003-03-28 | 2011-02-24 | ミグラスタチンアナログ組成物およびその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006523233A JP2006523233A (ja) | 2006-10-12 |
| JP2006523233A5 true JP2006523233A5 (enExample) | 2007-06-07 |
| JP4719671B2 JP4719671B2 (ja) | 2011-07-06 |
Family
ID=33135114
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006509369A Expired - Fee Related JP4719671B2 (ja) | 2003-03-28 | 2004-03-26 | ミグラスタチンアナログ組成物およびその使用 |
| JP2006509430A Expired - Fee Related JP4928937B2 (ja) | 2003-03-28 | 2004-03-26 | ミグラスタチンアナログおよびその使用 |
| JP2011039073A Withdrawn JP2011105766A (ja) | 2003-03-28 | 2011-02-24 | ミグラスタチンアナログ組成物およびその使用 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006509430A Expired - Fee Related JP4928937B2 (ja) | 2003-03-28 | 2004-03-26 | ミグラスタチンアナログおよびその使用 |
| JP2011039073A Withdrawn JP2011105766A (ja) | 2003-03-28 | 2011-02-24 | ミグラスタチンアナログ組成物およびその使用 |
Country Status (5)
| Country | Link |
|---|---|
| US (4) | US7943800B2 (enExample) |
| EP (2) | EP1613603A2 (enExample) |
| JP (3) | JP4719671B2 (enExample) |
| CA (2) | CA2520377A1 (enExample) |
| WO (2) | WO2004087672A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070037783A1 (en) * | 2003-03-28 | 2007-02-15 | Xin-Yun Huang | Migrastatin analogs and uses thereof |
| JP4719671B2 (ja) | 2003-03-28 | 2011-07-06 | コーネル・リサーチ・ファンデーション・インコーポレイテッド | ミグラスタチンアナログ組成物およびその使用 |
| US8957056B2 (en) | 2004-05-25 | 2015-02-17 | Sloan-Kettering Instiute For Cancer Research | Migrastatin analogs in the treatment of cancer |
| WO2006000923A2 (en) * | 2004-06-03 | 2006-01-05 | Novimmune Sa | Macrolide compositions as therapeutic agent |
| US8188141B2 (en) | 2004-09-23 | 2012-05-29 | Sloan-Kettering Institute For Cancer Research | Isomigrastatin analogs in the treatment of cancer |
| EP2170827B1 (en) * | 2007-06-21 | 2013-08-14 | Janssen Pharmaceutica, N.V. | Indolin-2-ones and aza-indolin-2-ones |
| WO2009110938A2 (en) * | 2007-12-10 | 2009-09-11 | Novobiotic Pharmaceuticals Llc | Novel macrocyclic polyene lactams |
| CN102076339A (zh) * | 2008-04-24 | 2011-05-25 | 百时美施贵宝公司 | 埃坡霉素D在治疗包括阿尔茨海默病的τ相关疾病中的用途 |
| AU2012239977B9 (en) | 2011-04-07 | 2016-11-17 | Sloan-Kettering Institute For Cancer Research | Migrastatins and uses thereof |
| WO2013013240A2 (en) * | 2011-07-21 | 2013-01-24 | Theracrine, Inc. | Macrocyclic compounds and related compositons and methods of use |
| CN108218932B (zh) * | 2017-12-27 | 2019-01-04 | 北京大学 | 凝集素受体介导的癌症预靶向治疗药物 |
| US11187655B2 (en) | 2018-05-16 | 2021-11-30 | Sensera, Inc. | Compact gas sensors |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL66434C (enExample) * | 1946-12-06 | |||
| FR1264032A (fr) | 1960-05-06 | 1961-06-19 | Rhone Poulenc Sa | Acide cycloundecanecarboxylique |
| GB1036084A (en) * | 1962-02-23 | 1966-07-13 | Upjohn Co | Oxygenated cycloalkanes and the preparation thereof |
| NL302921A (enExample) | 1963-01-21 | |||
| DE2934683A1 (de) | 1979-08-28 | 1981-03-12 | Haarmann & Reimer Gmbh, 3450 Holzminden | 3-methyl-cyclohexadecen-5-on-1, verfahren zu seiner herstellung und seine verwendung als riechstoff. |
| DE2934678A1 (de) | 1979-08-28 | 1981-03-12 | Haarmann & Reimer Gmbh, 3450 Holzminden | Cyclopentadecen-8-on-1, verfahren zu seiner herstellung und seine verwendung als riechstoff |
| US4472435A (en) | 1980-07-31 | 1984-09-18 | Hoffman-La Roche Inc. | Benzophenone derivatives useful in treating heart failure |
| JPS6156146A (ja) | 1984-08-28 | 1986-03-20 | Nippon Mining Co Ltd | 大環状ケトンの製造方法 |
| US4938949A (en) | 1988-09-12 | 1990-07-03 | University Of New York | Treatment of damaged bone marrow and dosage units therefor |
| EP0374445A1 (fr) | 1988-12-23 | 1990-06-27 | Firmenich Sa | Nouveaux composés cycliques oxygénés, leur utilisation à titre d'ingrédients parfumants, procédé pour leur préparation |
| JPH07138257A (ja) | 1993-11-16 | 1995-05-30 | Taisho Pharmaceut Co Ltd | 骨吸収抑制物質ｂｒ−０４０及びｂｒ−０４２ |
| AR043071A1 (es) | 1997-10-31 | 2005-07-20 | Abbott Lab | Uso de macrolidos para el tratamiento del cancer y degeneracion macular y una composicion farmaceutica |
| EP0976714A1 (en) | 1998-07-06 | 2000-02-02 | Quest International B.V. | Addition of ketones to alkenes |
| SG80643A1 (en) | 1998-09-03 | 2001-05-22 | Givaudan Roure Int | Methylcyclotetradec-5-en-1-ones |
| JP2000247949A (ja) | 1999-02-26 | 2000-09-12 | Eisai Co Ltd | スルホンアミド含有インドール化合物 |
| JP2001078793A (ja) | 1999-09-10 | 2001-03-27 | Nippon Kayaku Co Ltd | 新規生理活性物質の醗酵法による製造法 |
| JP2001081088A (ja) | 1999-09-10 | 2001-03-27 | Nippon Kayaku Co Ltd | 新規生理活性物質ｎｋ３０４２４類縁体とそれらの製造法および用途 |
| WO2001046451A1 (en) | 1999-12-22 | 2001-06-28 | Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai | Migrastatin, process for producing the same and medicinal compositions |
| US6750047B2 (en) * | 2000-08-21 | 2004-06-15 | Kosan Biosciences, Inc. | Fermentation and purification of migrastatin and analog |
| US6660306B2 (en) | 2000-10-12 | 2003-12-09 | Mickey L. Peshoff | Wound healing compound |
| TWI312681B (en) | 2001-02-01 | 2009-08-01 | Novel physiologically active substance | |
| AU2002254822A1 (en) | 2001-04-26 | 2002-11-11 | Ecopia Biosciences Inc. | Genes and proteins for the biosynthesis of polyketides |
| DE60216362T2 (de) * | 2001-06-08 | 2007-09-20 | Takasago International Corp. | Inhibitoren der Melaninherstellung und solche Inhibitoren enthaltende Hautpflegemittel |
| JP2003104967A (ja) | 2001-09-28 | 2003-04-09 | Takuma Sasaki | ウロキナーゼ産生阻害剤、血管新生阻害剤、癌転移抑制剤および抗腫瘍剤 |
| JP3973889B2 (ja) | 2001-12-04 | 2007-09-12 | 株式会社ジャパンエナジー | 大環状ケトン化合物の製造方法 |
| JP4463682B2 (ja) | 2002-07-23 | 2010-05-19 | ソシエテ ド テクノロジー ミシュラン | 補強構造体の非真直アンカーリングを備えたタイヤ |
| KR20050084224A (ko) | 2002-12-09 | 2005-08-26 | 더 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 | 야누스 티로신 키나제 3을 선택적으로 저해하는 방법 |
| JP4337815B2 (ja) | 2003-03-19 | 2009-09-30 | 宇部興産株式会社 | ω−シアノアルデヒド化合物の製造法 |
| US20070037783A1 (en) | 2003-03-28 | 2007-02-15 | Xin-Yun Huang | Migrastatin analogs and uses thereof |
| JP4719671B2 (ja) | 2003-03-28 | 2011-07-06 | コーネル・リサーチ・ファンデーション・インコーポレイテッド | ミグラスタチンアナログ組成物およびその使用 |
| WO2005019181A1 (en) | 2003-08-19 | 2005-03-03 | Cornell Research Foundation, Inc. | Migrastatin analog cell migration inhibitors |
| US8957056B2 (en) | 2004-05-25 | 2015-02-17 | Sloan-Kettering Instiute For Cancer Research | Migrastatin analogs in the treatment of cancer |
| US8188141B2 (en) | 2004-09-23 | 2012-05-29 | Sloan-Kettering Institute For Cancer Research | Isomigrastatin analogs in the treatment of cancer |
| CN101918036A (zh) | 2007-11-21 | 2010-12-15 | 康奈尔大学 | 抑制肌成束蛋白的方法 |
| EP2348845A4 (en) | 2008-10-15 | 2013-01-23 | Infinity Pharmaceuticals Inc | ANSAMYCIN HYDROQUINONE COMPOSITIONS |
-
2004
- 2004-03-26 JP JP2006509369A patent/JP4719671B2/ja not_active Expired - Fee Related
- 2004-03-26 US US10/551,158 patent/US7943800B2/en not_active Expired - Fee Related
- 2004-03-26 EP EP04758529A patent/EP1613603A2/en not_active Withdrawn
- 2004-03-26 WO PCT/US2004/009380 patent/WO2004087672A1/en not_active Ceased
- 2004-03-26 CA CA002520377A patent/CA2520377A1/en not_active Abandoned
- 2004-03-26 JP JP2006509430A patent/JP4928937B2/ja not_active Expired - Fee Related
- 2004-03-26 WO PCT/US2004/009571 patent/WO2004087673A2/en not_active Ceased
- 2004-03-26 EP EP04758436A patent/EP1608626A1/en not_active Withdrawn
- 2004-03-26 CA CA2520732A patent/CA2520732C/en not_active Expired - Fee Related
-
2011
- 2011-02-24 JP JP2011039073A patent/JP2011105766A/ja not_active Withdrawn
- 2011-03-21 US US13/053,161 patent/US8202911B2/en not_active Expired - Fee Related
- 2011-05-12 US US13/106,625 patent/US8324284B2/en not_active Expired - Fee Related
-
2012
- 2012-11-30 US US13/690,832 patent/US8835693B2/en not_active Expired - Fee Related
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