JP2006517384A5 - - Google Patents

Info

Publication number

JP2006517384A5

JP2006517384A5 JP2004519896A JP2004519896A JP2006517384A5 JP 2006517384 A5 JP2006517384 A5 JP 2006517384A5 JP 2004519896 A JP2004519896 A JP 2004519896A JP 2004519896 A JP2004519896 A JP 2004519896A JP 2006517384 A5 JP2006517384 A5 JP 2006517384A5

Authority

JP

Japan

Prior art keywords

seq

polypeptide

cell

pro71042

antibody

Prior art date

2003-07-08

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

• Espacenet
• Global Dossier
• Discuss

• 229920001184 polypeptide Polymers 0.000 claims 31
• 108090000765 processed proteins & peptides Proteins 0.000 claims 31
• 102000004196 processed proteins & peptides Human genes 0.000 claims 31
• 210000004027 cell Anatomy 0.000 claims 24
• 239000000523 sample Substances 0.000 claims 12
• 241000124008 Mammalia Species 0.000 claims 11
• 150000001875 compounds Chemical class 0.000 claims 8
• 201000010099 disease Diseases 0.000 claims 8
• 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 8
• 238000000034 method Methods 0.000 claims 8
• 150000007523 nucleic acids Chemical class 0.000 claims 8
• 108090000623 proteins and genes Proteins 0.000 claims 7
• 108091028043 Nucleic acid sequence Proteins 0.000 claims 5
• 239000013068 control sample Substances 0.000 claims 5
• 108020004707 nucleic acids Proteins 0.000 claims 5
• 102000039446 nucleic acids Human genes 0.000 claims 5
• 125000003275 alpha amino acid group Chemical group 0.000 claims 4
• 230000028993 immune response Effects 0.000 claims 4
• 239000000556 agonist Substances 0.000 claims 3
• 239000005557 antagonist Substances 0.000 claims 3
• 239000002773 nucleotide Substances 0.000 claims 3
• 125000003729 nucleotide group Chemical group 0.000 claims 3
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 2
• 210000003719 b-lymphocyte Anatomy 0.000 claims 2
• 230000015572 biosynthetic process Effects 0.000 claims 2
• 239000003814 drug Substances 0.000 claims 2
• 230000000694 effects Effects 0.000 claims 2
• 230000002757 inflammatory effect Effects 0.000 claims 2
• 230000004043 responsiveness Effects 0.000 claims 2
• 230000004936 stimulating effect Effects 0.000 claims 2
• 206010002556 Ankylosing Spondylitis Diseases 0.000 claims 1
• 208000011691 Burkitt lymphomas Diseases 0.000 claims 1
• 229940126062 Compound A Drugs 0.000 claims 1
• 241000588724 Escherichia coli Species 0.000 claims 1
• 206010018364 Glomerulonephritis Diseases 0.000 claims 1
• 208000035186 Hemolytic Autoimmune Anemia Diseases 0.000 claims 1
• NLDMNSXOCDLTTB-UHFFFAOYSA-N Heterophylliin A Natural products O1C2COC(=O)C3=CC(O)=C(O)C(O)=C3C3=C(O)C(O)=C(O)C=C3C(=O)OC2C(OC(=O)C=2C=C(O)C(O)=C(O)C=2)C(O)C1OC(=O)C1=CC(O)=C(O)C(O)=C1 NLDMNSXOCDLTTB-UHFFFAOYSA-N 0.000 claims 1
• 206010020751 Hypersensitivity Diseases 0.000 claims 1
• 208000007924 IgA Deficiency Diseases 0.000 claims 1
• 206010061598 Immunodeficiency Diseases 0.000 claims 1
• 208000029462 Immunodeficiency disease Diseases 0.000 claims 1
• 108060003951 Immunoglobulin Proteins 0.000 claims 1
• 206010025323 Lymphomas Diseases 0.000 claims 1
• 206010039915 Selective IgA immunodeficiency Diseases 0.000 claims 1
• 206010057863 Selective IgG subclass deficiency Diseases 0.000 claims 1
• 208000028483 Selective IgM deficiency Diseases 0.000 claims 1
• 208000026935 allergic disease Diseases 0.000 claims 1
• 230000000692 anti-sense effect Effects 0.000 claims 1
• 239000000427 antigen Substances 0.000 claims 1
• 108091007433 antigens Proteins 0.000 claims 1
• 102000036639 antigens Human genes 0.000 claims 1
• 201000000448 autoimmune hemolytic anemia Diseases 0.000 claims 1
• 238000004113 cell culture Methods 0.000 claims 1
• 210000004978 chinese hamster ovary cell Anatomy 0.000 claims 1
• 238000012258 culturing Methods 0.000 claims 1
• 230000007812 deficiency Effects 0.000 claims 1
• 229940079593 drug Drugs 0.000 claims 1
• 239000003937 drug carrier Substances 0.000 claims 1
• 201000003444 follicular lymphoma Diseases 0.000 claims 1
• 150000004676 glycans Chemical class 0.000 claims 1
• 230000009610 hypersensitivity Effects 0.000 claims 1
• 230000007813 immunodeficiency Effects 0.000 claims 1
• 102000018358 immunoglobulin Human genes 0.000 claims 1
• 201000007156 immunoglobulin alpha deficiency Diseases 0.000 claims 1
• 230000021633 leukocyte mediated immunity Effects 0.000 claims 1
• 238000004519 manufacturing process Methods 0.000 claims 1
• 230000001404 mediated effect Effects 0.000 claims 1
• 206010028417 myasthenia gravis Diseases 0.000 claims 1
• 229920001282 polysaccharide Polymers 0.000 claims 1
• 239000005017 polysaccharide Substances 0.000 claims 1
• 206010039073 rheumatoid arthritis Diseases 0.000 claims 1
• 208000029138 selective IgA deficiency disease Diseases 0.000 claims 1
• 208000016482 selective IgG deficiency disease Diseases 0.000 claims 1
• 201000000596 systemic lupus erythematosus Diseases 0.000 claims 1
• 230000001052 transient effect Effects 0.000 claims 1
• 210000005253 yeast cell Anatomy 0.000 claims 1