JP2006515851A5 - - Google Patents
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- Publication number
- JP2006515851A5 JP2006515851A5 JP2004562317A JP2004562317A JP2006515851A5 JP 2006515851 A5 JP2006515851 A5 JP 2006515851A5 JP 2004562317 A JP2004562317 A JP 2004562317A JP 2004562317 A JP2004562317 A JP 2004562317A JP 2006515851 A5 JP2006515851 A5 JP 2006515851A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- compound
- aryl
- group
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 CC(*)(*)C1=C=CC=CC1 Chemical compound CC(*)(*)C1=C=CC=CC1 0.000 description 11
- VYUVMRUHJYJXTD-HSZGREIDSA-N C[C@@H](CN(CC1)C(C)(CC2)CCN2C(c2c(C)ncnc2C)=O)N1C(C(CCC1)CN1S(C1CC1)(=O)=O)c1ccccc1 Chemical compound C[C@@H](CN(CC1)C(C)(CC2)CCN2C(c2c(C)ncnc2C)=O)N1C(C(CCC1)CN1S(C1CC1)(=O)=O)c1ccccc1 VYUVMRUHJYJXTD-HSZGREIDSA-N 0.000 description 2
- XNBWLXAXAAJBGB-UHFFFAOYSA-N C=NS(c1cc(Cl)ccc1)(=O)=O Chemical compound C=NS(c1cc(Cl)ccc1)(=O)=O XNBWLXAXAAJBGB-UHFFFAOYSA-N 0.000 description 1
- QHAYFDYTNMGMID-UHFFFAOYSA-N CC(CN(CC1)C(C)(CC2)CCN2C(c2c(C)ncnc2C)=O)N1C(C(C1)CN1C(C1CC1)=O)c1cccc(F)c1 Chemical compound CC(CN(CC1)C(C)(CC2)CCN2C(c2c(C)ncnc2C)=O)N1C(C(C1)CN1C(C1CC1)=O)c1cccc(F)c1 QHAYFDYTNMGMID-UHFFFAOYSA-N 0.000 description 1
- DIGCGGYEEOYANN-UHFFFAOYSA-O CC(CN(CC1)C(C)(CC2)CCN2C(c2c(C)ncnc2C)=O)N1C(Cc1ccccc1)C(C1)CN1S(C1CC1)([OH2+])=O Chemical compound CC(CN(CC1)C(C)(CC2)CCN2C(c2c(C)ncnc2C)=O)N1C(Cc1ccccc1)C(C1)CN1S(C1CC1)([OH2+])=O DIGCGGYEEOYANN-UHFFFAOYSA-O 0.000 description 1
- YPNAOMDXMAXBOT-AKWYTYQQSA-O CC(CN(CC1)C(C)(CC2)CCN2C(c2c(C)ncnc2C)=O)N1[C@@H](Cc1ccccc1)C(C1)CN1[SH+](c1ccccc1)(O)O Chemical compound CC(CN(CC1)C(C)(CC2)CCN2C(c2c(C)ncnc2C)=O)N1[C@@H](Cc1ccccc1)C(C1)CN1[SH+](c1ccccc1)(O)O YPNAOMDXMAXBOT-AKWYTYQQSA-O 0.000 description 1
- BWPZAUWSFKCBNG-UHFFFAOYSA-N CS(c1cc(Cl)ccc1)(=O)=O Chemical compound CS(c1cc(Cl)ccc1)(=O)=O BWPZAUWSFKCBNG-UHFFFAOYSA-N 0.000 description 1
- JCAKFAAVIVNFFY-RCVCLBTQSA-N C[C@@H](CN(CC1)C(C)(CC2)CCN2C(c2c(C)ncnc2C)=O)N1C(Cc1ccccc1)C(CCC1)CN1S(C1CC1)(=O)=O Chemical compound C[C@@H](CN(CC1)C(C)(CC2)CCN2C(c2c(C)ncnc2C)=O)N1C(Cc1ccccc1)C(CCC1)CN1S(C1CC1)(=O)=O JCAKFAAVIVNFFY-RCVCLBTQSA-N 0.000 description 1
- VPENCBMGPNOJDK-UQGZBABSSA-N C[C@@H](CN(CC1)C(C)(CC2)CCN2C(c2c(C)ncnc2C)=O)N1C(Cc1ccccc1)C(CCC1)CN1S(c1cccc(Cl)c1)(=O)=O Chemical compound C[C@@H](CN(CC1)C(C)(CC2)CCN2C(c2c(C)ncnc2C)=O)N1C(Cc1ccccc1)C(CCC1)CN1S(c1cccc(Cl)c1)(=O)=O VPENCBMGPNOJDK-UQGZBABSSA-N 0.000 description 1
- KBTWPLJKSAWUQM-GHXQVECXSA-N C[C@@H](CN(CC1)C(C)(CC2)CCN2C(c2c(C)ncnc2C)=O)N1C(Cc1ccccc1)C1CNCCC1 Chemical compound C[C@@H](CN(CC1)C(C)(CC2)CCN2C(c2c(C)ncnc2C)=O)N1C(Cc1ccccc1)C1CNCCC1 KBTWPLJKSAWUQM-GHXQVECXSA-N 0.000 description 1
- XICGQQYGDRWQND-UHFFFAOYSA-N O=S(c1cccc(Cl)c1)(I)=O Chemical compound O=S(c1cccc(Cl)c1)(I)=O XICGQQYGDRWQND-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US43430602P | 2002-12-18 | 2002-12-18 | |
| PCT/US2003/040619 WO2004056770A2 (en) | 2002-12-18 | 2003-12-17 | Piperidine derivatives useful as ccr5 antagonists |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006515851A JP2006515851A (ja) | 2006-06-08 |
| JP2006515851A5 true JP2006515851A5 (https=) | 2007-02-01 |
| JP4589728B2 JP4589728B2 (ja) | 2010-12-01 |
Family
ID=32682021
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004562317A Expired - Fee Related JP4589728B2 (ja) | 2002-12-18 | 2003-12-17 | Ｃｃｒ５アンタゴニストとして有用なピペリジン誘導体 |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US7307081B2 (https=) |
| EP (1) | EP1581494A2 (https=) |
| JP (1) | JP4589728B2 (https=) |
| KR (1) | KR20050085700A (https=) |
| CN (2) | CN101768152A (https=) |
| AR (1) | AR042481A1 (https=) |
| AU (1) | AU2003297400B2 (https=) |
| CA (1) | CA2510027A1 (https=) |
| CL (1) | CL2003002637A1 (https=) |
| MX (1) | MXPA05006580A (https=) |
| MY (1) | MY147899A (https=) |
| NZ (1) | NZ540452A (https=) |
| PE (1) | PE20040769A1 (https=) |
| TW (1) | TWI331606B (https=) |
| WO (1) | WO2004056770A2 (https=) |
| ZA (1) | ZA200504772B (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA015517B1 (ru) | 2004-04-13 | 2011-08-30 | Инсайт Корпорейшн | Производные пиперазинилпиперидина в качестве антагонистов хемокинового рецептора |
| WO2006071958A1 (en) | 2004-12-29 | 2006-07-06 | Millennium Pharmaceuticals, Inc. | Compounds useful as chemokine receptor antagonists |
| WO2006071875A1 (en) * | 2004-12-29 | 2006-07-06 | Millennium Pharmaceuticals, Inc. | Compounds useful as chemokine receptor antagonists |
| JP4822367B2 (ja) * | 2005-02-23 | 2011-11-24 | シェーリング コーポレイション | ケモカイン受容体のインヒビターとして有用なピペリジニルピペリジン誘導体 |
| EP1858887A1 (en) * | 2005-02-23 | 2007-11-28 | Schering Corporation | Piperidinyl piperazine derivatives useful as inhibitors of chemokine receptors |
| JP2009517474A (ja) * | 2005-11-30 | 2009-04-30 | シェーリング コーポレイション | Ｃｃｒ５拮抗剤およびｃｘｃｒ４拮抗剤の組み合わせを含む組成物 |
| WO2008030853A2 (en) * | 2006-09-06 | 2008-03-13 | Incyte Corporation | Combination therapy for human immunodeficiency virus infection |
| CA2673233A1 (en) * | 2006-12-22 | 2008-07-03 | Schering Corporation | Process for preparing ccr-5 receptor antagonists utilizing 4-substituted 1-cyclopropane-sulfonyl-piperidinyl compounds |
| JP7611949B2 (ja) * | 2023-01-27 | 2025-01-10 | 株式会社Ｓｃｒｅｅｎホールディングス | 基板保持装置及びそれを備えた基板処理装置 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5889006A (en) | 1995-02-23 | 1999-03-30 | Schering Corporation | Muscarinic antagonists |
| IL117149A0 (en) | 1995-02-23 | 1996-06-18 | Schering Corp | Muscarinic antagonists |
| DE19614204A1 (de) * | 1996-04-10 | 1997-10-16 | Thomae Gmbh Dr K | Carbonsäurederivate, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung |
| US5952349A (en) | 1996-07-10 | 1999-09-14 | Schering Corporation | Muscarinic antagonists for treating memory loss |
| US5977138A (en) | 1996-08-15 | 1999-11-02 | Schering Corporation | Ether muscarinic antagonists |
| KR100439357B1 (ko) * | 1999-05-04 | 2004-07-07 | 쉐링 코포레이션 | Ｃｃｒ５ 길항제로서 유용한 피페리딘 유도체 |
| SK287418B6 (sk) * | 1999-05-04 | 2010-09-07 | Schering Corporation | Farmaceutický prípravok s obsahom CCR5 antagonistov a súprava s obsahom tohto prípravku |
| JP4303969B2 (ja) * | 2001-03-29 | 2009-07-29 | シェーリング コーポレイション | Ｃｃｒ５アンタゴニストとして有用なアリールオキシム−ピペラジン |
| AR033452A1 (es) * | 2001-03-29 | 2003-12-17 | Schering Corp | Antagonistas de ccr5 utiles para el tratamiento del sida |
-
2003
- 2003-12-10 PE PE2003001245A patent/PE20040769A1/es not_active Application Discontinuation
- 2003-12-16 AR ARP030104646A patent/AR042481A1/es unknown
- 2003-12-16 MY MYPI20034821A patent/MY147899A/en unknown
- 2003-12-16 CL CL200302637A patent/CL2003002637A1/es unknown
- 2003-12-17 CN CN200910266072A patent/CN101768152A/zh active Pending
- 2003-12-17 MX MXPA05006580A patent/MXPA05006580A/es active IP Right Grant
- 2003-12-17 AU AU2003297400A patent/AU2003297400B2/en not_active Ceased
- 2003-12-17 EP EP03813796A patent/EP1581494A2/en not_active Withdrawn
- 2003-12-17 CN CN200380107119A patent/CN100591678C/zh not_active Expired - Fee Related
- 2003-12-17 US US10/738,907 patent/US7307081B2/en not_active Expired - Fee Related
- 2003-12-17 TW TW092135748A patent/TWI331606B/zh not_active IP Right Cessation
- 2003-12-17 CA CA002510027A patent/CA2510027A1/en not_active Abandoned
- 2003-12-17 JP JP2004562317A patent/JP4589728B2/ja not_active Expired - Fee Related
- 2003-12-17 WO PCT/US2003/040619 patent/WO2004056770A2/en not_active Ceased
- 2003-12-17 NZ NZ540452A patent/NZ540452A/en not_active IP Right Cessation
- 2003-12-17 KR KR1020057011055A patent/KR20050085700A/ko not_active Ceased
-
2006
- 2006-01-16 ZA ZA200504772A patent/ZA200504772B/en unknown
-
2007
- 2007-10-26 US US11/925,119 patent/US20080095740A1/en not_active Abandoned
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