JP2006515628A - ヒト神経精神疾患を処置するためのｎ−デスメチルクロザピンの使用 - Google Patents

ヒト神経精神疾患を処置するためのｎ−デスメチルクロザピンの使用 Download PDF

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JP2006515628A
JP2006515628A JP2006501063A JP2006501063A JP2006515628A JP 2006515628 A JP2006515628 A JP 2006515628A JP 2006501063 A JP2006501063 A JP 2006501063A JP 2006501063 A JP2006501063 A JP 2006501063A JP 2006515628 A JP2006515628 A JP 2006515628A
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desmethylclozapine
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additional therapeutic
therapeutic agent
reuptake inhibitor
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JP2006515628A5 (enExample
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ワイナー、デイヴィッド、エム．
ブラン、マーク、アール．
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アカディア ファーマシューティカルズ，インコーポレーテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hospice & Palliative Care (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2006501063A 2003-01-23 2004-01-21 ヒト神経精神疾患を処置するためのｎ−デスメチルクロザピンの使用 Withdrawn JP2006515628A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44269003P 2003-01-23 2003-01-23
PCT/US2004/001509 WO2004064753A2 (en) 2003-01-23 2004-01-21 Use of n-desmethylclozapine to treat human neuropsychiatric disease

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JP2006515628A true JP2006515628A (ja) 2006-06-01
JP2006515628A5 JP2006515628A5 (enExample) 2006-11-24

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JP2006501063A Withdrawn JP2006515628A (ja) 2003-01-23 2004-01-21 ヒト神経精神疾患を処置するためのｎ−デスメチルクロザピンの使用

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US (2) US20040224942A1 (enExample)
EP (2) EP1589974A2 (enExample)
JP (1) JP2006515628A (enExample)
KR (1) KR20050092123A (enExample)
CN (1) CN1741803A (enExample)
AU (1) AU2004206931A1 (enExample)
BR (1) BRPI0406592A (enExample)
CA (1) CA2512043A1 (enExample)
MX (1) MXPA05007784A (enExample)
NZ (1) NZ541014A (enExample)
RU (2) RU2336879C2 (enExample)
SG (1) SG159390A1 (enExample)
WO (1) WO2004064753A2 (enExample)
ZA (1) ZA200505878B (enExample)

Cited By (2)

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Publication number Priority date Publication date Assignee Title
JP2009506069A (ja) * 2005-08-26 2009-02-12 ブレインセルス，インコーポレイティド ムスカリン性受容体調節による神経発生
JP2013544838A (ja) * 2010-12-03 2013-12-19 アラーガン インコーポレイテッド 網膜の疾患を治療するための方法

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WO2004064753A3 (en) 2004-11-25
US20090018119A1 (en) 2009-01-15
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RU2008116931A (ru) 2009-11-10
US20040224942A1 (en) 2004-11-11
AU2004206931A1 (en) 2004-08-05
SG159390A1 (en) 2010-03-30
EP1589974A2 (en) 2005-11-02
EP1994932A1 (en) 2008-11-26
CA2512043A1 (en) 2004-08-05
RU2336879C2 (ru) 2008-10-27
BRPI0406592A (pt) 2005-12-20
WO2004064753A2 (en) 2004-08-05
KR20050092123A (ko) 2005-09-20
MXPA05007784A (es) 2005-09-30
RU2005126614A (ru) 2006-01-27
ZA200505878B (en) 2006-04-26

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