ZA200505878B - Use of N-desmethylclozapine to treat human neuropsychiatric disease - Google Patents
Use of N-desmethylclozapine to treat human neuropsychiatric disease Download PDFInfo
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- ZA200505878B ZA200505878B ZA200505878A ZA200505878A ZA200505878B ZA 200505878 B ZA200505878 B ZA 200505878B ZA 200505878 A ZA200505878 A ZA 200505878A ZA 200505878 A ZA200505878 A ZA 200505878A ZA 200505878 B ZA200505878 B ZA 200505878B
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Landscapes
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| ATE466014T1 (de) | 2001-12-28 | 2010-05-15 | Acadia Pharm Inc | Spiroazacyclische verbindungen als monoaminrezeptormodulatoren |
| US7538222B2 (en) | 2002-06-24 | 2009-05-26 | Acadia Pharmaceuticals, Inc. | N-substituted piperidine derivatives as serotonin receptor agents |
| US7253186B2 (en) | 2002-06-24 | 2007-08-07 | Carl-Magnus Andersson | N-substituted piperidine derivatives as serotonin receptor agents |
| MXPA04012893A (es) | 2002-06-24 | 2005-03-31 | Acadia Pharm Inc | Derivados de piperidina n-substituidos como agentes receptores de serotonina. |
| US7601740B2 (en) | 2003-01-16 | 2009-10-13 | Acadia Pharmaceuticals, Inc. | Selective serotonin 2A/2C receptor inverse agonists as therapeutics for neurodegenerative diseases |
| US20050250767A1 (en) * | 2003-01-23 | 2005-11-10 | Weiner David M | Use of N-desmethylclozapine to treat human neuropsychiatric disease |
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| EP1589974A2 (en) * | 2003-01-23 | 2005-11-02 | Acadia Pharmaceuticals Inc. | Use of n-desmethylclozapine to treat human neuropsychiatric disease |
| EP1596867A4 (en) * | 2003-02-19 | 2006-03-22 | Merck & Co Inc | TREATMENT OF PSYCHOSIS WITH A MUSCARIN M1 RECEPTOR ECTOPIC ACTIVATOR |
| US20060217365A1 (en) * | 2003-07-02 | 2006-09-28 | Astrazeneca Ab | Method of treating mood disorders |
| US20060252743A1 (en) * | 2005-01-07 | 2006-11-09 | Astrazeneca Ab | Method of treating sleep disorders |
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| US20060229292A1 (en) * | 2005-01-07 | 2006-10-12 | Astrazeneca Ab | Method of treating childhood disorders |
| DE602004028739D1 (de) * | 2003-07-02 | 2010-09-30 | Astrazeneca Ab | Metabolit von quetiapine |
| US20090093460A1 (en) * | 2003-07-02 | 2009-04-09 | Astrazeneca Ab | Compositions |
| US20060217366A1 (en) * | 2003-07-02 | 2006-09-28 | Astrazeneca Ab | Method of treating schizophrenia and other disorders |
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| US20090239840A1 (en) * | 2003-12-22 | 2009-09-24 | Acadia Pharmaceuticals, Inc. | AMINO SUBSTITUTED DIARYL[a,d]CYCLOHEPTENE ANALOGS AS MUSCARINIC AGONISTS AND METHODS OF TREATMENT OF NEUROPSYCHIATRIC DISORDERS |
| PL1696931T3 (pl) | 2003-12-22 | 2009-10-30 | Acadia Pharm Inc | Aminopodstawione analogi diarylo[A,D]cykloheptenowe jako agoniści receptorów muskarynowych i sposoby leczenia chorób neuropsychiatrycznych |
| US20050171088A1 (en) * | 2004-01-30 | 2005-08-04 | Astrazeneca Ab | Treatment of psychoses with dibenzothiazepine antipsychotic |
| RU2006138497A (ru) * | 2004-04-01 | 2008-05-10 | Акадиа Фармасьютикалз Инк. (Us) | Кристаллические формы n-десметилклозапина |
| US7820695B2 (en) | 2004-05-21 | 2010-10-26 | Acadia Pharmaceuticals, Inc. | Selective serotonin receptor inverse agonists as therapeutics for disease |
| US20050261278A1 (en) * | 2004-05-21 | 2005-11-24 | Weiner David M | Selective serotonin receptor inverse agonists as therapeutics for disease |
| JP2008509147A (ja) * | 2004-08-05 | 2008-03-27 | アカディア ファーマシューティカルズ，インコーポレーテッド | ヒト神経精神病を治療するためのｎ−デスメチルクロザピンの使用 |
| DK1794126T3 (da) * | 2004-09-27 | 2013-06-24 | Acadia Pharm Inc | Krystallinsk form af N-(-4-fluorbenzyl)-N-(1-methylpiperidn-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl)carbamid-hemitartrat |
| US7790899B2 (en) | 2004-09-27 | 2010-09-07 | Acadia Pharmaceuticals, Inc. | Synthesis of N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N′-(4-(2-methylpropyloxy)phenylmethyl)carbamide and its tartrate salt and crystalline forms |
| EP1865962A2 (en) * | 2005-04-04 | 2007-12-19 | Arcadia Pharmaceuticals Inc. | Use of n-desmethylclozapine and related compounds as dopamine stabilizing agents |
| CA2620333A1 (en) * | 2005-08-26 | 2007-03-01 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation |
| US20070105836A1 (en) * | 2005-10-31 | 2007-05-10 | Lars Pettersson | Prodrugs of muscarinic agonists and methods of treatment of neuropsychiatric disorders |
| WO2007148341A2 (en) | 2006-06-22 | 2007-12-27 | Ramot At Tel Aviv University Ltd. | Novel serotonin reuptake inhibitors as drugs having peripheral-system-restricted activity |
| US9278947B2 (en) | 2006-06-22 | 2016-03-08 | Ramot At Tel-Aviv University Ltd. | Serotonin reuptake inhibitors as drugs having peripheral-system-restricted activity |
| ES2423485T3 (es) | 2007-03-19 | 2013-09-20 | Acadia Pharmaceuticals Inc. | Asociaciones de agonistas y antagonistas inversos 5-HT2A con antipsicóticos |
| PL2307389T3 (pl) * | 2008-06-20 | 2013-05-31 | Astrazeneca Ab | Pochodne dibenzotiazepiny i ich zastosowanie |
| US9018202B2 (en) * | 2010-12-03 | 2015-04-28 | Allergan, Inc. | Methods for treating diseases of the retina |
| RU2506073C1 (ru) * | 2012-09-06 | 2014-02-10 | Алексей Николаевич Паршин | Способ лечения расстройства адаптации у пациентов с суицидальным риском |
| US20160184290A1 (en) * | 2014-12-31 | 2016-06-30 | Paul J. Markovitz | Method of treating schizophrenia |
| ES2890492T3 (es) | 2015-07-20 | 2022-01-20 | Acadia Pharm Inc | Métodos para preparar N-(4-fluorobencil)-N-(1-metilpiperidin-4-il)-N'-(4-(2-metilpropiloxi)fenilmetil)carbamida y su sal de tartrato y forma polimórfica C |
| WO2017117347A1 (en) * | 2015-12-30 | 2017-07-06 | Markovitz M D Paul | Method of treating schizophrenia |
| RU2667954C2 (ru) * | 2016-03-04 | 2018-09-25 | Общество С Ограниченной Ответственностью "Валентек" | Фармацевтическая композиция для лечения функциональных психических расстройств |
| WO2017165635A1 (en) | 2016-03-25 | 2017-09-28 | Acadia Pharmaceuticals Inc. | Combination of pimavanserin and cytochrome p450 modulators |
| US10953000B2 (en) | 2016-03-25 | 2021-03-23 | Acadia Pharmaceuticals Inc. | Combination of pimavanserin and cytochrome P450 modulators |
| WO2018118626A1 (en) | 2016-12-20 | 2018-06-28 | Acadia Pharmaceuticals Inc. | Pimavanserin alone or in combination for use in the treatment of alzheimer's disease psychosis |
| EP3615028A1 (en) | 2017-04-28 | 2020-03-04 | Acadia Pharmaceuticals Inc. | Pimavanserin for treating impulse control disorder |
| EP3675827A1 (en) | 2017-08-30 | 2020-07-08 | Acadia Pharmaceuticals Inc. | Formulations of pimavanserin |
| US12459965B2 (en) | 2017-10-09 | 2025-11-04 | Compass Pathfinder Limited | Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use |
| GB2571696B (en) | 2017-10-09 | 2020-05-27 | Compass Pathways Ltd | Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced |
| CN107970243B (zh) * | 2017-10-30 | 2020-07-28 | 江苏理工学院 | 一种去甲氯氮平的新用途 |
| CN109761826B (zh) * | 2019-01-17 | 2022-02-25 | 烟台大学 | 一种o-去甲基文拉法辛苯醚化合物及其制备方法和用途 |
| CN113993523A (zh) | 2019-04-17 | 2022-01-28 | 指南针探路者有限公司 | 用赛洛西宾治疗抑郁症和其他各种病症 |
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| NL140242B (nl) * | 1963-03-01 | 1973-11-15 | Wander Ag Dr A | Werkwijze voor het bereiden van op de 11-plaats door een basische groep gesubstitueerde dibenz (b.f.)(1.4) oxazepinen. |
| US3389139A (en) * | 1963-06-14 | 1968-06-18 | Wander Ag Dr A | 6-homopiperazino and piperazinomorphanthridines |
| US3908010A (en) * | 1967-03-22 | 1975-09-23 | Wander Ag Dr A | Basically substituted heterocycles as anti-emetics |
| US3884920A (en) * | 1967-07-14 | 1975-05-20 | Sandoz Ag | 11-Basically substituted dibenz {8 b,f{9 {0 {8 1,4{9 {0 oxazepines |
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-
2004
- 2004-01-21 EP EP04704073A patent/EP1589974A2/en not_active Ceased
- 2004-01-21 MX MXPA05007784A patent/MXPA05007784A/es not_active Application Discontinuation
- 2004-01-21 WO PCT/US2004/001509 patent/WO2004064753A2/en not_active Ceased
- 2004-01-21 BR BR0406592-1A patent/BRPI0406592A/pt not_active IP Right Cessation
- 2004-01-21 KR KR1020057013323A patent/KR20050092123A/ko not_active Withdrawn
- 2004-01-21 US US10/761,787 patent/US20040224942A1/en not_active Abandoned
- 2004-01-21 EP EP08016004A patent/EP1994932A1/en not_active Withdrawn
- 2004-01-21 CA CA002512043A patent/CA2512043A1/en not_active Abandoned
- 2004-01-21 JP JP2006501063A patent/JP2006515628A/ja not_active Withdrawn
- 2004-01-21 CN CNA200480002642XA patent/CN1741803A/zh active Pending
- 2004-01-21 NZ NZ541014A patent/NZ541014A/en unknown
- 2004-01-21 AU AU2004206931A patent/AU2004206931A1/en not_active Abandoned
- 2004-01-21 SG SG200705214-5A patent/SG159390A1/en unknown
- 2004-01-21 RU RU2005126614/15A patent/RU2336879C2/ru not_active IP Right Cessation
-
2005
- 2005-07-21 ZA ZA200505878A patent/ZA200505878B/en unknown
-
2008
- 2008-04-28 RU RU2008116931/14A patent/RU2008116931A/ru not_active Application Discontinuation
- 2008-09-22 US US12/235,526 patent/US20090018119A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| NZ541014A (en) | 2008-05-30 |
| WO2004064753A3 (en) | 2004-11-25 |
| US20090018119A1 (en) | 2009-01-15 |
| CN1741803A (zh) | 2006-03-01 |
| RU2008116931A (ru) | 2009-11-10 |
| US20040224942A1 (en) | 2004-11-11 |
| AU2004206931A1 (en) | 2004-08-05 |
| SG159390A1 (en) | 2010-03-30 |
| EP1589974A2 (en) | 2005-11-02 |
| EP1994932A1 (en) | 2008-11-26 |
| CA2512043A1 (en) | 2004-08-05 |
| RU2336879C2 (ru) | 2008-10-27 |
| JP2006515628A (ja) | 2006-06-01 |
| BRPI0406592A (pt) | 2005-12-20 |
| WO2004064753A2 (en) | 2004-08-05 |
| KR20050092123A (ko) | 2005-09-20 |
| MXPA05007784A (es) | 2005-09-30 |
| RU2005126614A (ru) | 2006-01-27 |
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