JP2006510740A - 出血と関連した神経系障害を治療する方法 - Google Patents

出血と関連した神経系障害を治療する方法 Download PDF

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Publication number
JP2006510740A
JP2006510740A JP2005507039A JP2005507039A JP2006510740A JP 2006510740 A JP2006510740 A JP 2006510740A JP 2005507039 A JP2005507039 A JP 2005507039A JP 2005507039 A JP2005507039 A JP 2005507039A JP 2006510740 A JP2006510740 A JP 2006510740A
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Japan
Prior art keywords
tudca
bleeding
administration
bcl
patient
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English (en)
Japanese (ja)
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JP2006510740A5 (enExample
Inventor
ジェイ． ステア，クリフォード
シー． ロウ，ウォルター
エミ．ペー． ロドリゲス，セシリア
ナン，チェンホン
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University of Minnesota Twin Cities
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University of Minnesota System
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Publication of JP2006510740A publication Critical patent/JP2006510740A/ja
Publication of JP2006510740A5 publication Critical patent/JP2006510740A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
JP2005507039A 2002-11-07 2003-10-08 出血と関連した神経系障害を治療する方法 Pending JP2006510740A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US42521002P 2002-11-07 2002-11-07
US45161503P 2003-03-03 2003-03-03
PCT/US2003/031989 WO2004043342A2 (en) 2002-11-07 2003-10-08 Methods of treating injuries of the nervous system associated with hemorrhage

Publications (2)

Publication Number Publication Date
JP2006510740A true JP2006510740A (ja) 2006-03-30
JP2006510740A5 JP2006510740A5 (enExample) 2006-11-24

Family

ID=32314576

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2005507039A Pending JP2006510740A (ja) 2002-11-07 2003-10-08 出血と関連した神経系障害を治療する方法

Country Status (8)

Country Link
US (1) US20060135494A1 (enExample)
EP (1) EP1575578B1 (enExample)
JP (1) JP2006510740A (enExample)
KR (1) KR20050103185A (enExample)
AT (1) ATE451108T1 (enExample)
AU (1) AU2003275495A1 (enExample)
DE (1) DE60330501D1 (enExample)
WO (1) WO2004043342A2 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7772220B2 (en) 2004-10-15 2010-08-10 Seo Hong Yoo Methods and compositions for reducing toxicity of a pharmaceutical compound
US20030044413A1 (en) * 2000-08-15 2003-03-06 Regents Of The University Of Minnesota Methods of limiting apoptosis of cells
US20060204481A1 (en) * 2003-04-02 2006-09-14 Steer Clifford J Methods of promoting cell viability
ES2339790T3 (es) 2004-08-30 2010-05-25 Seo Hong Yoo Efecto neuroprotector de udca solubilizado en modelo isquemico focal.
CA2584184A1 (en) 2004-10-15 2006-04-27 Seo Hong Yoo Methods and compositions for reducing toxicity of a pharmaceutical compound
KR20080012258A (ko) * 2005-02-10 2008-02-11 리전츠 오브 더 유니버스티 오브 미네소타 시각장애를 치료하는 방법
US20090312297A1 (en) * 2006-03-22 2009-12-17 President And Fellows Of Harvard College Methods for treating hypercholesterolemia and atherosclerosis
KR20180029317A (ko) * 2016-09-12 2018-03-21 경상대학교산학협력단 간손상 예방, 개선 또는 치료용 조성물
KR101953298B1 (ko) * 2017-07-18 2019-02-28 의료법인 성광의료재단 우르소데옥시콜산을 함유하는 염증성 질환 또는 척수 손상 예방 또는 치료용 조성물

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002011708A2 (en) * 2000-08-04 2002-02-14 Symphar S.A. Methods for inducing apolipoprotein e secretion

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0552373T3 (da) * 1991-07-03 1999-12-27 Otsuka Pharma Co Ltd Apoptoseregulator
US5656725A (en) * 1995-05-12 1997-08-12 Apoptosis Technology, Inc. Peptides and compositions which modulate apoptosis
WO1999015179A1 (en) * 1997-09-25 1999-04-01 Regents Of The University Of Minnesota Methods of limiting apoptosis of cells
EP1056464A1 (en) * 1998-02-27 2000-12-06 Nutramax Laboratories, Inc. L-ergothioneine, milk thistle, and s-adenosylmethionine for the prevention, treatment and repair of liver damage
US20030044413A1 (en) * 2000-08-15 2003-03-06 Regents Of The University Of Minnesota Methods of limiting apoptosis of cells

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002011708A2 (en) * 2000-08-04 2002-02-14 Symphar S.A. Methods for inducing apolipoprotein e secretion

Also Published As

Publication number Publication date
AU2003275495A1 (en) 2004-06-03
AU2003275495A8 (en) 2004-06-03
KR20050103185A (ko) 2005-10-27
ATE451108T1 (de) 2009-12-15
EP1575578B1 (en) 2009-12-09
DE60330501D1 (de) 2010-01-21
HK1086479A1 (zh) 2006-09-22
US20060135494A1 (en) 2006-06-22
WO2004043342A3 (en) 2004-07-15
EP1575578A4 (en) 2007-10-10
EP1575578A2 (en) 2005-09-21
WO2004043342A2 (en) 2004-05-27

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