KR20050103185A - 출혈과 관련된 신경계 손상의 치료 방법 - Google Patents

출혈과 관련된 신경계 손상의 치료 방법 Download PDF

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Publication number
KR20050103185A
KR20050103185A KR1020057008192A KR20057008192A KR20050103185A KR 20050103185 A KR20050103185 A KR 20050103185A KR 1020057008192 A KR1020057008192 A KR 1020057008192A KR 20057008192 A KR20057008192 A KR 20057008192A KR 20050103185 A KR20050103185 A KR 20050103185A
Authority
KR
South Korea
Prior art keywords
tudca
bleeding
patient
bcl
ursodeoxycholic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1020057008192A
Other languages
English (en)
Korean (ko)
Inventor
클리포드 제이. 스틸러
왈터 씨. 로우
세실리아 엠. 피. 로드리게스
전홍 난
Original Assignee
리전츠 오브 더 유니버스티 오브 미네소타
클리포드 제이. 스틸러
왈터 씨. 로우
세실리아 엠. 피. 로드리게스
전홍 난
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 리전츠 오브 더 유니버스티 오브 미네소타, 클리포드 제이. 스틸러, 왈터 씨. 로우, 세실리아 엠. 피. 로드리게스, 전홍 난 filed Critical 리전츠 오브 더 유니버스티 오브 미네소타
Publication of KR20050103185A publication Critical patent/KR20050103185A/ko
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
KR1020057008192A 2002-11-07 2003-10-08 출혈과 관련된 신경계 손상의 치료 방법 Withdrawn KR20050103185A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US42521002P 2002-11-07 2002-11-07
US60/425,210 2002-11-07
US45161503P 2003-03-03 2003-03-03
US60/451,615 2003-03-03

Publications (1)

Publication Number Publication Date
KR20050103185A true KR20050103185A (ko) 2005-10-27

Family

ID=32314576

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020057008192A Withdrawn KR20050103185A (ko) 2002-11-07 2003-10-08 출혈과 관련된 신경계 손상의 치료 방법

Country Status (8)

Country Link
US (1) US20060135494A1 (enExample)
EP (1) EP1575578B1 (enExample)
JP (1) JP2006510740A (enExample)
KR (1) KR20050103185A (enExample)
AT (1) ATE451108T1 (enExample)
AU (1) AU2003275495A1 (enExample)
DE (1) DE60330501D1 (enExample)
WO (1) WO2004043342A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018048274A1 (ko) * 2016-09-12 2018-03-15 경상대학교 산학협력단 간손상 예방, 개선 또는 치료용 조성물
KR20190009174A (ko) * 2017-07-18 2019-01-28 의료법인 성광의료재단 우르소데옥시콜산을 함유하는 염증성 질환 또는 척수 손상 예방 또는 치료용 조성물

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7772220B2 (en) 2004-10-15 2010-08-10 Seo Hong Yoo Methods and compositions for reducing toxicity of a pharmaceutical compound
US20030044413A1 (en) * 2000-08-15 2003-03-06 Regents Of The University Of Minnesota Methods of limiting apoptosis of cells
US20060204481A1 (en) * 2003-04-02 2006-09-14 Steer Clifford J Methods of promoting cell viability
CN101035541B (zh) * 2004-08-30 2012-05-30 柳署弘 溶解的udca在局灶缺血模型中的神经保护作用
AU2005295541B2 (en) 2004-10-15 2011-02-17 Seo Hong Yoo Methods and compositions for reducing toxicity of a pharmaceutical compound
US20080194531A1 (en) * 2005-02-10 2008-08-14 Steer Clifford J Methods for Treating Visual Disorders
CN101534641A (zh) * 2006-03-22 2009-09-16 哈佛大学校长及研究员协会 治疗高胆固醇血症和动脉粥样硬化的方法和组合物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2090876A1 (en) * 1991-07-03 1993-01-04 Satoru Nakai Apoptosis regulating composition
US5656725A (en) * 1995-05-12 1997-08-12 Apoptosis Technology, Inc. Peptides and compositions which modulate apoptosis
US6544972B1 (en) * 1997-09-25 2003-04-08 Regents Of The University Of Minnesota Methods of limiting apoptosis of cells
US6555141B1 (en) * 1998-02-27 2003-04-29 Nutramax Laboratories, Inc. L-ergothioneine, Milk thistle, and S-adenosylmethionine for the prevention, treatment and repair of liver damage
GB0019290D0 (en) * 2000-08-04 2000-09-27 Symphar Sa Methods for inducing apolipoprotein E secretion
US20030044413A1 (en) * 2000-08-15 2003-03-06 Regents Of The University Of Minnesota Methods of limiting apoptosis of cells

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018048274A1 (ko) * 2016-09-12 2018-03-15 경상대학교 산학협력단 간손상 예방, 개선 또는 치료용 조성물
KR20190009174A (ko) * 2017-07-18 2019-01-28 의료법인 성광의료재단 우르소데옥시콜산을 함유하는 염증성 질환 또는 척수 손상 예방 또는 치료용 조성물

Also Published As

Publication number Publication date
EP1575578A4 (en) 2007-10-10
JP2006510740A (ja) 2006-03-30
DE60330501D1 (de) 2010-01-21
EP1575578B1 (en) 2009-12-09
US20060135494A1 (en) 2006-06-22
WO2004043342A3 (en) 2004-07-15
AU2003275495A8 (en) 2004-06-03
WO2004043342A2 (en) 2004-05-27
HK1086479A1 (zh) 2006-09-22
EP1575578A2 (en) 2005-09-21
AU2003275495A1 (en) 2004-06-03
ATE451108T1 (de) 2009-12-15

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PA0105 International application

Patent event date: 20050507

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
N231 Notification of change of applicant
PN2301 Change of applicant

Patent event date: 20051123

Comment text: Notification of Change of Applicant

Patent event code: PN23011R01D

PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid