DK0552373T3 - Apoptoseregulator - Google Patents

Apoptoseregulator

Info

Publication number
DK0552373T3
DK0552373T3 DK92914177T DK92914177T DK0552373T3 DK 0552373 T3 DK0552373 T3 DK 0552373T3 DK 92914177 T DK92914177 T DK 92914177T DK 92914177 T DK92914177 T DK 92914177T DK 0552373 T3 DK0552373 T3 DK 0552373T3
Authority
DK
Denmark
Prior art keywords
apoptosis regulator
apoptosis
regulator
Prior art date
Application number
DK92914177T
Other languages
English (en)
Inventor
Satoru Nakai
Masakazu Adachi
Koutoku Aihara
Hitomi Mori
Michiaki Tominaga
Hiroyuki Ichikawa
Seiji Akamatsu
Fumio Saito
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Application granted granted Critical
Publication of DK0552373T3 publication Critical patent/DK0552373T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
DK92914177T 1991-07-03 1992-07-02 Apoptoseregulator DK0552373T3 (da)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP16258791 1991-07-03
JP3346992 1992-02-20
JP4571892 1992-03-03
JP10058592 1992-03-25
PCT/JP1992/000841 WO1993000902A1 (en) 1991-07-03 1992-07-02 Apoptosis regulator

Publications (1)

Publication Number Publication Date
DK0552373T3 true DK0552373T3 (da) 1999-12-27

Family

ID=27459795

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92914177T DK0552373T3 (da) 1991-07-03 1992-07-02 Apoptoseregulator

Country Status (12)

Country Link
US (5) US5672603A (da)
EP (1) EP0552373B1 (da)
KR (1) KR100196368B1 (da)
AU (1) AU648690B2 (da)
CA (1) CA2090876A1 (da)
DE (1) DE69230131T2 (da)
DK (1) DK0552373T3 (da)
ES (1) ES2138971T3 (da)
HK (1) HK1004469A1 (da)
MX (1) MX9203950A (da)
TW (1) TW229157B (da)
WO (1) WO1993000902A1 (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5464833A (en) * 1992-08-19 1995-11-07 Otsuka Pharmaceutical Co., Ltd. Apoptosis regulating composition
WO1994020107A1 (en) * 1993-03-02 1994-09-15 Otsuka Pharmaceutical Co., Ltd. Rejection inhibitor for transplants and il-1 production inhibitor
GB9311132D0 (en) 1993-05-28 1993-07-14 Eisai London Res Lab Ltd Control of cell death
CN1073418C (zh) * 1993-10-21 2001-10-24 大塚制药株式会社 白细胞介素－8生成抑制剂
US5504093A (en) * 1994-08-01 1996-04-02 Otsuka Pharmaceutical Co., Ltd. Method for inhibiting nucleoside and nucleobase transport in mammalian cells, and method for inhibition of DNA virus replication
CA2185246A1 (en) * 1995-01-11 1996-07-18 Hideo Tanaka Pharmaceutical composition of indene derivatives for regulating apoptosis
WO1998046229A1 (fr) * 1995-06-21 1998-10-22 Otsuka Pharmaceutical Co., Ltd. Inhibiteurs de la production d'il-8 et du mcaf
JPH0971532A (ja) * 1995-09-06 1997-03-18 Otsuka Pharmaceut Co Ltd 発癌抑制剤
US5700803A (en) * 1995-12-12 1997-12-23 Otsuka Pharmaceutical Co., Ltd. Method for reducing infarct size in subjects afflicted with ischemic heart disease
AU6854398A (en) * 1997-04-25 1998-11-24 Otsuka Pharmaceutical Co., Ltd. Hyaluronate synthesis inhibitors
US6008209A (en) * 1997-04-28 1999-12-28 Hoffmann-La Roche Inc. Method of using vitamin D3 analogs with bis C-20 side chains
US6544972B1 (en) 1997-09-25 2003-04-08 Regents Of The University Of Minnesota Methods of limiting apoptosis of cells
US6281191B1 (en) 1997-12-29 2001-08-28 Vladimir I. Slesarev Compositions and methods for treating hepatitis-C
FR2774289B1 (fr) * 1998-02-03 2002-05-24 Goemar Lab Sa Medicament pour le traitement des dereglements de l'apoptose
EP1096955B9 (en) 1998-07-13 2006-07-05 Board of Regents, The University of Texas System Uses of antibodies to aminophospholipids for cancer treatment
EP1234585A3 (en) 1998-09-04 2004-01-21 The Regents Of The University Of Michigan Methods and compositions for the prevention or treatment of cancer
US6277974B1 (en) 1999-12-14 2001-08-21 Cogent Neuroscience, Inc. Compositions and methods for diagnosing and treating conditions, disorders, or diseases involving cell death
US20030044413A1 (en) * 2000-08-15 2003-03-06 Regents Of The University Of Minnesota Methods of limiting apoptosis of cells
EP1467767A2 (en) * 2001-12-20 2004-10-20 Cogent Neuroscience, Inc. Methods for treating conditions,disorders,or diseases involving cell death
BR0312692A (pt) 2002-07-15 2007-06-26 Univ Texas anticorpos selecionados e peptìdeos de duramicina que se ligam a fosfolipìdios aniÈnicos e aminofosfolipìdios e seus usos no tratamento de infecções virais e cáncer
KR20050103185A (ko) * 2002-11-07 2005-10-27 리전츠 오브 더 유니버스티 오브 미네소타 출혈과 관련된 신경계 손상의 치료 방법
WO2008109433A2 (en) 2007-03-02 2008-09-12 The Cleveland Clinic Foundation Anti-angiogenic peptides
US20060204481A1 (en) * 2003-04-02 2006-09-14 Steer Clifford J Methods of promoting cell viability
KR101535395B1 (ko) 2004-01-22 2015-07-08 유니버시티 오브 마이애미 국소용 코-엔자임 큐10 제형 및 그의 사용 방법
KR20080012258A (ko) * 2005-02-10 2008-02-11 리전츠 오브 더 유니버스티 오브 미네소타 시각장애를 치료하는 방법
JP5809415B2 (ja) 2007-11-09 2015-11-10 ペレグリン ファーマシューティカルズ，インコーポレーテッド 抗ｖｅｇｆ抗体の組成物および方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5430184A (en) * 1977-08-10 1979-03-06 Otsuka Pharmaceut Co Ltd 3,4-dihydrocarbostyril derivative
JPS6038384B2 (ja) * 1978-03-24 1985-08-31 大塚製薬株式会社 チオセミカルバゾン誘導体
JPS5777676A (en) * 1980-10-31 1982-05-15 Otsuka Pharmaceut Co Ltd Carbostyril derivative
JPS5793962A (en) * 1980-12-01 1982-06-11 Otsuka Pharmaceut Co Ltd Carbostyryl derivative
JPS62135423A (ja) * 1985-12-09 1987-06-18 Otsuka Pharmaceut Co Ltd 低酸素症改善剤

Also Published As

Publication number Publication date
EP0552373A4 (en) 1993-09-22
DE69230131T2 (de) 2000-03-02
CA2090876A1 (en) 1993-01-04
EP0552373A1 (en) 1993-07-28
KR100196368B1 (ko) 1999-06-15
US5872120A (en) 1999-02-16
US5925640A (en) 1999-07-20
HK1004469A1 (en) 1998-11-27
KR930702002A (ko) 1993-09-08
WO1993000902A1 (en) 1993-01-21
DE69230131D1 (de) 1999-11-18
AU2231792A (en) 1993-02-11
US5798358A (en) 1998-08-25
EP0552373B1 (en) 1999-10-13
AU648690B2 (en) 1994-04-28
US5916890A (en) 1999-06-29
ES2138971T3 (es) 2000-02-01
TW229157B (da) 1994-09-01
US5672603A (en) 1997-09-30
MX9203950A (es) 1993-05-01

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