TW229157B - - Google Patents

Info

Publication number
TW229157B
TW229157B TW081105603A TW81105603A TW229157B TW 229157 B TW229157 B TW 229157B TW 081105603 A TW081105603 A TW 081105603A TW 81105603 A TW81105603 A TW 81105603A TW 229157 B TW229157 B TW 229157B
Authority
TW
Taiwan
Application number
TW081105603A
Inventor
Seiji Akamatsu
Fumio Saitou
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Application granted granted Critical
Publication of TW229157B publication Critical patent/TW229157B/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
TW081105603A 1991-07-03 1992-07-15 TW229157B (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP16258791 1991-07-03
JP3346992 1992-02-20
JP4571892 1992-03-03
JP10058592 1992-03-25

Publications (1)

Publication Number Publication Date
TW229157B true TW229157B (zh) 1994-09-01

Family

ID=27459795

Family Applications (1)

Application Number Title Priority Date Filing Date
TW081105603A TW229157B (zh) 1991-07-03 1992-07-15

Country Status (12)

Country Link
US (5) US5672603A (zh)
EP (1) EP0552373B1 (zh)
KR (1) KR100196368B1 (zh)
AU (1) AU648690B2 (zh)
CA (1) CA2090876A1 (zh)
DE (1) DE69230131T2 (zh)
DK (1) DK0552373T3 (zh)
ES (1) ES2138971T3 (zh)
HK (1) HK1004469A1 (zh)
MX (1) MX9203950A (zh)
TW (1) TW229157B (zh)
WO (1) WO1993000902A1 (zh)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994004504A1 (en) * 1992-08-19 1994-03-03 Otsuka Pharmaceutical Co., Ltd. Apoptosis regulator
US5521185A (en) * 1993-03-02 1996-05-28 Otsuka Pharmaceutical Co., Ltd. Methods for inhibiting graft rejection and IL-1 production
GB9311132D0 (en) 1993-05-28 1993-07-14 Eisai London Res Lab Ltd Control of cell death
AU683697B2 (en) * 1993-10-21 1997-11-20 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivative for inhibiting production of interleukin-8
US5504093A (en) * 1994-08-01 1996-04-02 Otsuka Pharmaceutical Co., Ltd. Method for inhibiting nucleoside and nucleobase transport in mammalian cells, and method for inhibition of DNA virus replication
EP0749311A1 (en) * 1995-01-11 1996-12-27 Otsuka Pharmaceutical Co., Ltd. Pharmaceutical composition of indene derivatives for regulating apoptosis
WO1998046229A1 (fr) * 1995-06-21 1998-10-22 Otsuka Pharmaceutical Co., Ltd. Inhibiteurs de la production d'il-8 et du mcaf
JPH0971532A (ja) * 1995-09-06 1997-03-18 Otsuka Pharmaceut Co Ltd 発癌抑制剤
US5700803A (en) * 1995-12-12 1997-12-23 Otsuka Pharmaceutical Co., Ltd. Method for reducing infarct size in subjects afflicted with ischemic heart disease
AU6854398A (en) * 1997-04-25 1998-11-24 Otsuka Pharmaceutical Co., Ltd. Hyaluronate synthesis inhibitors
US6008209A (en) * 1997-04-28 1999-12-28 Hoffmann-La Roche Inc. Method of using vitamin D3 analogs with bis C-20 side chains
US6544972B1 (en) 1997-09-25 2003-04-08 Regents Of The University Of Minnesota Methods of limiting apoptosis of cells
US6281191B1 (en) 1997-12-29 2001-08-28 Vladimir I. Slesarev Compositions and methods for treating hepatitis-C
FR2774289B1 (fr) * 1998-02-03 2002-05-24 Goemar Lab Sa Medicament pour le traitement des dereglements de l'apoptose
JP4743672B2 (ja) 1998-07-13 2011-08-10 ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム アミノリン脂質に対する抗体を用いる癌処置方法
SI1107795T1 (en) 1998-09-04 2003-06-30 The Regents Of The University Of Michigan Thiomolybdate associated with at least one carbohydrate, and its use for preventing or treating diseases characterized by aberrant vascularization, such as cancer, wet type macular degeneration, rheumatoid arthritis
US6277974B1 (en) 1999-12-14 2001-08-21 Cogent Neuroscience, Inc. Compositions and methods for diagnosing and treating conditions, disorders, or diseases involving cell death
US20030044413A1 (en) * 2000-08-15 2003-03-06 Regents Of The University Of Minnesota Methods of limiting apoptosis of cells
AU2002360665A1 (en) * 2001-12-20 2003-07-09 Cogent Neuroscience, Inc. Methods for treating conditions, disorders, or diseases involving cell death
DK1537146T3 (da) 2002-07-15 2011-04-04 Univ Texas Antistoffer, der binder til anioniske phospholipider og aminophospholipider, og deres anvendelse til behandling af virusinfektioner
EP1575578B1 (en) * 2002-11-07 2009-12-09 Regents Of The University Of Minnesota Methods of treating injuries of the nervous system associated with hemorrhage
WO2008109433A2 (en) 2007-03-02 2008-09-12 The Cleveland Clinic Foundation Anti-angiogenic peptides
US20060204481A1 (en) * 2003-04-02 2006-09-14 Steer Clifford J Methods of promoting cell viability
US8147825B2 (en) 2004-01-22 2012-04-03 University Of Miami Topical co-enzyme Q10 formulations and methods of use
WO2006086452A1 (en) * 2005-02-10 2006-08-17 Regents Of The University Of Minnesota Methods for treating visual disorders
EP2614837A1 (en) 2007-11-09 2013-07-17 Affitech Research AS Anti-VEGF antibody compositions and methods

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5430184A (en) * 1977-08-10 1979-03-06 Otsuka Pharmaceut Co Ltd 3,4-dihydrocarbostyril derivative
JPS6038384B2 (ja) * 1978-03-24 1985-08-31 大塚製薬株式会社 チオセミカルバゾン誘導体
JPS5777676A (en) * 1980-10-31 1982-05-15 Otsuka Pharmaceut Co Ltd Carbostyril derivative
JPS5793962A (en) * 1980-12-01 1982-06-11 Otsuka Pharmaceut Co Ltd Carbostyryl derivative
JPS62135423A (ja) * 1985-12-09 1987-06-18 Otsuka Pharmaceut Co Ltd 低酸素症改善剤

Also Published As

Publication number Publication date
EP0552373A4 (en) 1993-09-22
EP0552373B1 (en) 1999-10-13
AU2231792A (en) 1993-02-11
WO1993000902A1 (en) 1993-01-21
EP0552373A1 (en) 1993-07-28
KR930702002A (ko) 1993-09-08
US5872120A (en) 1999-02-16
DK0552373T3 (da) 1999-12-27
US5916890A (en) 1999-06-29
DE69230131D1 (de) 1999-11-18
ES2138971T3 (es) 2000-02-01
DE69230131T2 (de) 2000-03-02
KR100196368B1 (ko) 1999-06-15
US5672603A (en) 1997-09-30
CA2090876A1 (en) 1993-01-04
MX9203950A (es) 1993-05-01
HK1004469A1 (en) 1998-11-27
US5925640A (en) 1999-07-20
AU648690B2 (en) 1994-04-28
US5798358A (en) 1998-08-25

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