JP2006510348A5 - - Google Patents

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Publication number
JP2006510348A5
JP2006510348A5 JP2004523488A JP2004523488A JP2006510348A5 JP 2006510348 A5 JP2006510348 A5 JP 2006510348A5 JP 2004523488 A JP2004523488 A JP 2004523488A JP 2004523488 A JP2004523488 A JP 2004523488A JP 2006510348 A5 JP2006510348 A5 JP 2006510348A5
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JP
Japan
Prior art keywords
group
nucleic acid
acid probe
fluorescence
fluorescence quenching
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2004523488A
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English (en)
Japanese (ja)
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JP2006510348A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2003/022320 external-priority patent/WO2004010101A2/en
Publication of JP2006510348A publication Critical patent/JP2006510348A/ja
Publication of JP2006510348A5 publication Critical patent/JP2006510348A5/ja
Pending legal-status Critical Current

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JP2004523488A 2002-07-18 2003-07-17 蛍光消光脱離基を用いる化学ライゲーションの検出 Pending JP2006510348A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39677402P 2002-07-18 2002-07-18
PCT/US2003/022320 WO2004010101A2 (en) 2002-07-18 2003-07-17 Detection of chemical ligation using fluorescence quenching leaving groups

Publications (2)

Publication Number Publication Date
JP2006510348A JP2006510348A (ja) 2006-03-30
JP2006510348A5 true JP2006510348A5 (enExample) 2008-08-14

Family

ID=30770949

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004523488A Pending JP2006510348A (ja) 2002-07-18 2003-07-17 蛍光消光脱離基を用いる化学ライゲーションの検出

Country Status (6)

Country Link
US (1) US7749699B2 (enExample)
EP (1) EP1543156A4 (enExample)
JP (1) JP2006510348A (enExample)
AU (1) AU2003256587A1 (enExample)
CA (1) CA2492048A1 (enExample)
WO (1) WO2004010101A2 (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7033753B1 (en) 1999-01-15 2006-04-25 University Of Rochester Compositions and methods for nonenzymatic ligation of oligonucleotides and detection of genetic polymorphisms
US7745614B2 (en) 2004-09-03 2010-06-29 The Board Of Trustees Of The Leland Stanford Junior University Universal linker compositions for the release or transfer of chemical agents from a polynucleotide
CA2610027A1 (en) * 2005-05-26 2006-11-30 Ensemble Discovery Corporation Biodetection by nucleic acid-templated chemistry
EP2677039B8 (en) * 2006-05-10 2022-10-05 DxTerity Diagnostics Incorporated Detection of nucleic acid targets using chemically reactive oligonucleotide probes
JP2008259453A (ja) * 2007-04-12 2008-10-30 Toyobo Co Ltd 核酸の検出方法
KR102231531B1 (ko) 2009-02-13 2021-03-23 엑스-켐, 인크. Dna―코딩된 라이브러리의 생성 및 스크리닝 방법
DK2414544T3 (da) 2009-04-01 2014-06-16 Dxterity Diagnostics Inc Probe-amplifikations-afhængig kemisk ligering
WO2012077819A1 (ja) 2010-12-10 2012-06-14 国立大学法人 東京工業大学 標的核酸の検出方法及びキット
WO2012142003A2 (en) 2011-04-15 2012-10-18 Life Technologies Corporation Chemical ligation
CN106434871B (zh) 2011-05-17 2020-08-18 德克斯特里蒂诊断公司 用于检测目标核酸的方法与组合物
ES2675111T3 (es) 2011-09-07 2018-07-06 X-Chem, Inc. Métodos para etiquetar bibliotecas con codificación de ADN
CN104685115A (zh) 2012-07-13 2015-06-03 X-化学有限公司 具有聚合酶不可读的编码性寡核苷酸连接的dna编码文库
MX371428B (es) 2013-08-19 2020-01-30 Singular Bio Inc Ensayos para la deteccion de una sola molecula y uso de los mismos.
JP6739339B2 (ja) 2014-01-15 2020-08-12 アボット・ラボラトリーズAbbott Laboratories カバーされた配列変換dnaおよび検出方法
EP3154696B1 (en) 2014-06-10 2020-04-08 DxTerity Diagnostics Incorporated Devices and methods for collecting and stabilizing biological samples
JP6773651B2 (ja) * 2014-10-14 2020-10-21 アボット・ラボラトリーズAbbott Laboratories ポリdnaスペーサー配列を有する配列変換およびシグナル増幅dnaならびにそれらを用いた検出方法
US10604790B2 (en) 2014-12-24 2020-03-31 Abbott Laboratories Sequence conversion and signal amplifier DNA cascade reactions and detection methods using same
AU2016219943A1 (en) 2015-02-18 2017-10-12 Singular Bio, Inc. Assays for single molecule detection and use thereof
EP3350350B1 (en) * 2015-11-19 2021-04-14 Pacific Biosciences of California, Inc. Compounds and systems for improving signal detection

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5476925A (en) 1993-02-01 1995-12-19 Northwestern University Oligodeoxyribonucleotides including 3'-aminonucleoside-phosphoramidate linkages and terminal 3'-amino groups
WO1994024143A1 (en) 1993-04-12 1994-10-27 Northwestern University Method of forming oligonucleotides
US5681943A (en) 1993-04-12 1997-10-28 Northwestern University Method for covalently linking adjacent oligonucleotides
US5925517A (en) * 1993-11-12 1999-07-20 The Public Health Research Institute Of The City Of New York, Inc. Detectably labeled dual conformation oligonucleotide probes, assays and kits
EP0826066B1 (en) * 1995-05-05 2000-09-13 The Perkin-Elmer Corporation Methods and reagents for combined pcr amplification and hybridization probing assay
US6080868A (en) * 1998-01-23 2000-06-27 The Perkin-Elmer Corporation Nitro-substituted non-fluorescent asymmetric cyanine dye compounds
US5952202A (en) * 1998-03-26 1999-09-14 The Perkin Elmer Corporation Methods using exogenous, internal controls and analogue blocks during nucleic acid amplification

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