JP2006506384A - 肥満の治療のためのメラノコルチン受容体リガンドとしての２−アルキル−（２−アミノ−３−アリール−プロピオニル）−ピペラジン誘導体及び関連化合物 - Google Patents

肥満の治療のためのメラノコルチン受容体リガンドとしての２−アルキル−（２−アミノ−３−アリール−プロピオニル）−ピペラジン誘導体及び関連化合物 Download PDF

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JP2006506384A
JP2006506384A JP2004546990A JP2004546990A JP2006506384A JP 2006506384 A JP2006506384 A JP 2006506384A JP 2004546990 A JP2004546990 A JP 2004546990A JP 2004546990 A JP2004546990 A JP 2004546990A JP 2006506384 A JP2006506384 A JP 2006506384A
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ethyl
oxo
piperazin
methyl
fluorophenyl
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Japanese (ja)
Inventor
ハロック エベチーノ フランク
シンロン ティアン
アダム メーザー ウィースロウ
コルソン アニー−オディル
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Procter and Gamble Co
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Procter and Gamble Co
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    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
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    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
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    • C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
    • C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
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    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
JP2004546990A 2002-10-23 2003-10-22 肥満の治療のためのメラノコルチン受容体リガンドとしての２−アルキル−（２−アミノ−３−アリール−プロピオニル）−ピペラジン誘導体及び関連化合物 Pending JP2006506384A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42057802P 2002-10-23 2002-10-23
PCT/US2003/033402 WO2004037797A2 (en) 2002-10-23 2003-10-22 2 - alkyl - (2 - amino - 3 - aryl - propionyl) - piperazine derivatives and related compounds as melanocortin receptor ligands for the treatment of obesity

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JP2006506384A true JP2006506384A (ja) 2006-02-23

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EP (1) EP1556361A2 (US07132539-20061107-C00077.png)
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CN (1) CN1703221A (US07132539-20061107-C00077.png)
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KR101478253B1 (ko) * 2007-09-17 2014-12-31 국민대학교산학협력단 아룸 팔래스티눔(Ａｒｕｍ ｐａｌａｅｓｔｉｎｕｎＢｏｉｓｓ) 유래 항암용 피페라지움 화합물
WO2017022733A1 (ja) * 2015-08-04 2017-02-09 アステラス製薬株式会社 ピペラジン誘導体

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US7132539B2 (en) 2006-11-07
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EP1556361A2 (en) 2005-07-27
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CA2501231A1 (en) 2004-05-06
RU2005111967A (ru) 2006-01-20
US20050010031A1 (en) 2005-01-13
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BR0315614A (pt) 2005-08-30
KR20050072445A (ko) 2005-07-11
MXPA05004378A (es) 2005-07-05
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AU2003286557A1 (en) 2004-05-13
AR043054A1 (es) 2005-07-13

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