JP2006505502A5 - - Google Patents
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- JP2006505502A5 JP2006505502A5 JP2003586180A JP2003586180A JP2006505502A5 JP 2006505502 A5 JP2006505502 A5 JP 2006505502A5 JP 2003586180 A JP2003586180 A JP 2003586180A JP 2003586180 A JP2003586180 A JP 2003586180A JP 2006505502 A5 JP2006505502 A5 JP 2006505502A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- composition
- peptide
- amino acid
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37391402P | 2002-04-19 | 2002-04-19 | |
| PCT/CA2003/000502 WO2003089460A1 (en) | 2002-04-19 | 2003-04-07 | Immunological methods and compositions for the treatment of alzheimer's disease |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009251464A Division JP5345920B2 (ja) | 2002-04-19 | 2009-10-30 | アルツハイマー病の処置のための免疫学的方法および組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006505502A JP2006505502A (ja) | 2006-02-16 |
| JP2006505502A5 true JP2006505502A5 (https=) | 2006-06-01 |
| JP4662719B2 JP4662719B2 (ja) | 2011-03-30 |
Family
ID=29251102
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003586180A Expired - Fee Related JP4662719B2 (ja) | 2002-04-19 | 2003-04-07 | アルツハイマー病の処置のための免疫学的方法および組成物 |
| JP2009251464A Expired - Fee Related JP5345920B2 (ja) | 2002-04-19 | 2009-10-30 | アルツハイマー病の処置のための免疫学的方法および組成物 |
| JP2012249078A Withdrawn JP2013075898A (ja) | 2002-04-19 | 2012-11-13 | アルツハイマー病の処置のための免疫学的方法および組成物 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009251464A Expired - Fee Related JP5345920B2 (ja) | 2002-04-19 | 2009-10-30 | アルツハイマー病の処置のための免疫学的方法および組成物 |
| JP2012249078A Withdrawn JP2013075898A (ja) | 2002-04-19 | 2012-11-13 | アルツハイマー病の処置のための免疫学的方法および組成物 |
Country Status (17)
| Country | Link |
|---|---|
| US (5) | US20030232758A1 (https=) |
| EP (2) | EP1497321B1 (https=) |
| JP (3) | JP4662719B2 (https=) |
| KR (1) | KR100994748B1 (https=) |
| CN (1) | CN100360555C (https=) |
| AT (1) | ATE514707T1 (https=) |
| AU (1) | AU2003218560B2 (https=) |
| CA (1) | CA2481952C (https=) |
| ES (1) | ES2368907T3 (https=) |
| IL (3) | IL164643A0 (https=) |
| MX (1) | MXPA04010255A (https=) |
| NO (2) | NO335192B1 (https=) |
| NZ (1) | NZ536064A (https=) |
| PL (1) | PL209696B1 (https=) |
| SG (1) | SG173214A1 (https=) |
| WO (1) | WO2003089460A1 (https=) |
| ZA (1) | ZA200408811B (https=) |
Families Citing this family (65)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1309341A2 (en) | 2000-07-07 | 2003-05-14 | Lars Lannfelt | Prevention and treatment of alzheimer's disease |
| WO2003039467A2 (en) * | 2001-11-02 | 2003-05-15 | Diagenics International Corporation | Monoclonal antibodies specific for beta-amyloid. |
| US20050106626A1 (en) * | 2002-10-20 | 2005-05-19 | George Pieczenik | Ligand binding of amyloid peptide protein epitope |
| DE10303974A1 (de) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
| SE0401601D0 (sv) | 2004-06-21 | 2004-06-21 | Bioarctic Neuroscience Ab | Protofibril specific antibodies and uses thereof |
| US8193250B2 (en) | 2004-10-22 | 2012-06-05 | Mount Sinai School Of Medicine | Compositions and methods for treating alzheimer's disease and related disorders and promoting a healthy nervous system |
| US20090123952A1 (en) * | 2004-11-12 | 2009-05-14 | Pfizer, Inc. | Method of Measuring Amyloid-Beta Peptides |
| PL2289909T3 (pl) | 2005-11-30 | 2015-04-30 | Abbvie Inc | Sposób przeszukiwania, proces oczyszczania niedyfundujących oligomerów Abeta, selektywne przeciwciała przeciw niedyfundującym oligomerom Abeta i sposób wytwarzania tych przeciwciał |
| RU2432362C2 (ru) | 2005-11-30 | 2011-10-27 | Эбботт Лэборетриз | Моноклональные антитела и их применения |
| SG10201404801YA (en) | 2005-12-12 | 2014-09-26 | Ac Immune Sa | Monoclonal antibody |
| EP1992639A4 (en) * | 2006-02-22 | 2009-08-26 | Hayashibara Biochem Lab | PEPTIDE VACCINE FOR INDUCING THE PRODUCTION OF AN ANTIAMYLOID PEPTIDANT BODY |
| RU2429244C2 (ru) | 2006-03-23 | 2011-09-20 | Байоарктик Ньюросайенс Аб | Улучшенные селективные в отношении протофибрилл антитела и их применение |
| WO2007126111A1 (ja) * | 2006-04-28 | 2007-11-08 | Kagoshima University | アミロイドβ線維化阻害ペプチド |
| NZ574188A (en) | 2006-07-14 | 2012-05-25 | Ac Immune Sa | Humanized antibody against amyloid beta |
| US8455626B2 (en) | 2006-11-30 | 2013-06-04 | Abbott Laboratories | Aβ conformer selective anti-aβ globulomer monoclonal antibodies |
| WO2008143708A2 (en) * | 2006-12-07 | 2008-11-27 | Mayo Foundation For Medical Education And Research | Methods and materials related to anti-amyloid antibodies |
| HRP20140049T1 (hr) | 2007-01-05 | 2014-02-28 | University Of Zürich | Anti beta-amiloid antitijela i njihova upotreba |
| EP2124952A2 (en) | 2007-02-27 | 2009-12-02 | Abbott GmbH & Co. KG | Method for the treatment of amyloidoses |
| AU2008220785B2 (en) | 2007-03-01 | 2013-02-21 | Vivoryon Therapeutics N.V. | New use of glutaminyl cyclase inhibitors |
| JP5667440B2 (ja) | 2007-04-18 | 2015-02-12 | プロビオドルグ エージー | グルタミニルシクラーゼ阻害剤としてのチオ尿素誘導体 |
| US8048420B2 (en) | 2007-06-12 | 2011-11-01 | Ac Immune S.A. | Monoclonal antibody |
| US8613923B2 (en) | 2007-06-12 | 2013-12-24 | Ac Immune S.A. | Monoclonal antibody |
| RS53174B (sr) | 2007-10-05 | 2014-06-30 | Genentech Inc. | Upotreba antiamiloidnog beta antitela u slučaju oboljenja oka |
| US8815794B2 (en) * | 2008-08-28 | 2014-08-26 | The Research Foundation For The State University Of New York | Treatment of amyloidoses using myelin basic protein and fragments thereof |
| US8912145B2 (en) | 2008-11-28 | 2014-12-16 | Hokko Chemical Industry Co., Ltd. | Vaccine composition for prophylaxis and/or therapy of Alzheimer's disease |
| EP2365071B1 (en) * | 2008-11-28 | 2016-04-06 | Hokko Chemical Industry Co., Ltd. | Transformed soybean plant which stores vaccine, and use thereof |
| CN101797493B (zh) * | 2009-02-06 | 2014-05-21 | 上海抗体药物国家工程研究中心有限公司 | 一种在反应釜中制备亲和层析介质的方法 |
| CN101486768B (zh) * | 2009-02-25 | 2012-05-30 | 吉林大学 | 一种用于治疗阿尔茨海默氏病的抗原蛋白及蛋白基因 |
| WO2010124028A2 (en) * | 2009-04-21 | 2010-10-28 | Vasylyev Sergiy V | Light collection and illumination systems employing planar waveguide |
| JP5934645B2 (ja) | 2009-09-11 | 2016-06-15 | プロビオドルグ エージー | グルタミニルシクラーゼ阻害剤としてのヘテロ環式誘導体 |
| WO2011107530A2 (en) | 2010-03-03 | 2011-09-09 | Probiodrug Ag | Novel inhibitors |
| JP5688745B2 (ja) | 2010-03-10 | 2015-03-25 | プロビオドルグ エージー | グルタミニルシクラーゼ(qc、ec2.3.2.5)の複素環阻害剤 |
| ES2684475T3 (es) | 2010-04-15 | 2018-10-03 | Abbvie Inc. | Proteínas que se unen a beta amiloide |
| WO2011131748A2 (en) | 2010-04-21 | 2011-10-27 | Probiodrug Ag | Novel inhibitors |
| RU2607368C2 (ru) | 2010-07-30 | 2017-01-10 | Ац Иммуне С.А. | Безопасные и функциональные гуманизированные антитела |
| CN103298833B (zh) | 2010-08-14 | 2015-12-16 | Abbvie公司 | β淀粉样蛋白结合蛋白 |
| US20120321694A1 (en) * | 2010-10-27 | 2012-12-20 | Daniel Larocque | Compositions and uses |
| EP2686313B1 (en) | 2011-03-16 | 2016-02-03 | Probiodrug AG | Benzimidazole derivatives as inhibitors of glutaminyl cyclase |
| DE102011057019A1 (de) * | 2011-12-23 | 2013-06-27 | Forschungszentrum Jülich GmbH | Standard zur Quantifizierung von pathogenen Aggregaten aus körpereigenen Proteinen |
| MX366972B (es) * | 2012-01-20 | 2019-08-01 | Ananth Annapragada | Metodos y composiciones para caracterizar imagenes medicas en forma objetiva. |
| US9534048B2 (en) * | 2012-08-24 | 2017-01-03 | University Health Network | Antibodies to TTR and methods of use |
| EA201590459A1 (ru) * | 2012-09-12 | 2015-11-30 | Нейриммьюн Холдинг Аг | Специфические антитела к островковому амилоидному полипептиду человека (hiapp) и их применение |
| RU2689674C2 (ru) | 2012-10-15 | 2019-05-28 | Медиммьюн Лимитед | Антитела к бета-амилоиду |
| EP3027205A4 (en) | 2013-07-28 | 2017-07-19 | Qantu Therapeutics, Inc. | Vaccine formulations that induce a th2 immune response |
| PL3137094T3 (pl) | 2014-04-29 | 2023-03-13 | Advantage Therapeutics, Inc. | Leczenie i profilaktyka choroby alzheimera (ad) |
| EP3166970B1 (en) | 2014-07-10 | 2021-03-10 | BioArctic AB | Improved a-beta protofibril binding antibodies |
| MA41115A (fr) | 2014-12-02 | 2017-10-10 | Biogen Int Neuroscience Gmbh | Procédé de traitement de la maladie d'alzheimer |
| US10759837B2 (en) * | 2015-11-09 | 2020-09-01 | The University Of British Columbia | Anti-amyloid beta antibodies binding to a cyclic amyloid beta peptide |
| CN108699134A (zh) * | 2015-12-10 | 2018-10-23 | 国家生物技术研究所公司 | 淀粉样β-蛋白前体抑制剂结构域的变体 |
| BR112019009711A2 (pt) * | 2016-11-25 | 2019-08-13 | Genuv Inc | método de indução de neuro-regeneração, método de proteção de neurônios contra perda ou dano neuronal, método de prevenção ou tratamento de doença neurodegenerativa devido à perda ou dano neuronal, e método de triagem de candidatos de fármaco para o tratamento de doenças neurodegenerativas |
| AU2018308088B2 (en) | 2017-07-25 | 2025-05-29 | Truebinding, Inc. | Treating cancer by blocking the interaction of TIM-3 and its ligand |
| IL272773B2 (en) | 2017-08-22 | 2024-06-01 | Biogen Ma Inc | Pharmaceutical preparations containing anti-amyloid cell antibodies |
| ES2812698T3 (es) | 2017-09-29 | 2021-03-18 | Probiodrug Ag | Inhibidores de glutaminil ciclasa |
| KR102710762B1 (ko) | 2017-10-25 | 2024-09-25 | 얀센 파마슈티칼즈, 인코포레이티드 | 인산화 타우 펩티드의 조성물 및 이의 용도 |
| CA3099946A1 (en) * | 2018-05-18 | 2019-11-21 | Universite Laval | Use of nod2 agonist for the treatment, prophylaxis and/or delay of the onset of multiple sclerosis and alzheimer's disease |
| AU2020214796A1 (en) | 2019-01-30 | 2021-07-29 | Truebinding, Inc. | Anti-Gal3 antibodies and uses thereof |
| AU2020219804A1 (en) | 2019-02-08 | 2021-08-19 | Ac Immune S.A. | Method of safe administration of phosphorylated Tau peptide vaccine |
| JP7505713B2 (ja) * | 2019-02-22 | 2024-06-25 | ロヨラ メリーマウント ユニバーシティ | アミロイドペプチドバリアント |
| EA202192891A1 (ru) | 2019-04-24 | 2022-02-04 | Янссен Фармасьютикалз, Инк. | Гетерологичное введение анти-тау вакцин |
| WO2021157634A1 (ja) * | 2020-02-05 | 2021-08-12 | 大日本住友製薬株式会社 | タウオパチーおよび認知症関連疾患の判定薬および判定方法 |
| TW202144387A (zh) * | 2020-02-11 | 2021-12-01 | 美商聯合生物醫學公司 | 針對胰島澱粉樣多肽(iapp)的胜肽免疫原及其預防和治療與聚集iapp相關疾病的製劑 |
| CN116234562A (zh) * | 2020-05-15 | 2023-06-06 | 非营利性组织佛兰芒综合大学生物技术研究所 | 用于治疗病理性聚集的手段和方法 |
| WO2021242776A2 (en) | 2020-05-26 | 2021-12-02 | Truebinding, Inc. | Methods of treating inflammatory diseases by blocking galectin-3 |
| CN115925987A (zh) * | 2022-02-28 | 2023-04-07 | 安域生物科技(杭州)有限公司 | 基于β-淀粉样蛋白修饰的抗原多肽及其应用 |
| CN115786260B (zh) * | 2022-12-26 | 2024-08-20 | 海南大学 | Aβ42-hIAPP共寡聚化物诱导的AD脑类器官病理模型方法 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4235877A (en) | 1979-06-27 | 1980-11-25 | Merck & Co., Inc. | Liposome particle containing viral or bacterial antigenic subunit |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US4666829A (en) * | 1985-05-15 | 1987-05-19 | University Of California | Polypeptide marker for Alzheimer's disease and its use for diagnosis |
| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| US5770429A (en) | 1990-08-29 | 1998-06-23 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5814318A (en) | 1990-08-29 | 1998-09-29 | Genpharm International Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5874299A (en) | 1990-08-29 | 1999-02-23 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| DK0671948T3 (da) | 1992-06-25 | 1997-09-01 | Smithkline Beecham Biolog | Vaccinepræparat indeholdende adjuvanser |
| US5766846A (en) * | 1992-07-10 | 1998-06-16 | Athena Neurosciences | Methods of screening for compounds which inhibit soluble β-amyloid peptide production |
| US5840294A (en) | 1993-03-29 | 1998-11-24 | Queen's University At Kingston | Method for treating amyloidosis |
| AU687805B2 (en) * | 1993-04-27 | 1998-03-05 | United Biomedical Inc. | Immunogenic LHRH peptide constructs and synthetic universal immune stimulators for vaccines |
| US5759551A (en) | 1993-04-27 | 1998-06-02 | United Biomedical, Inc. | Immunogenic LHRH peptide constructs and synthetic universal immune stimulators for vaccines |
| US5744144A (en) | 1993-07-30 | 1998-04-28 | University Of Pittsburgh University Patent Committee Policy And Procedures | Synthetic multiple tandem repeat mucin and mucin-like peptides, and uses thereof |
| GB9326253D0 (en) | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
| UA56132C2 (uk) | 1995-04-25 | 2003-05-15 | Смітклайн Бічем Байолоджікалс С.А. | Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини |
| WO1997007402A1 (en) | 1995-08-17 | 1997-02-27 | The Ontario Cancer Institute | Protein fibril assembly assay |
| US7964192B1 (en) * | 1997-12-02 | 2011-06-21 | Janssen Alzheimer Immunotherapy | Prevention and treatment of amyloidgenic disease |
| US6750324B1 (en) * | 1997-12-02 | 2004-06-15 | Neuralab Limited | Humanized and chimeric N-terminal amyloid beta-antibodies |
| SI1292187T1 (sl) | 2000-06-20 | 2006-10-31 | Univ Toronto | Transgenski zivalski model nevrodegenerativnih motenj |
| US6310810B1 (en) | 2000-07-14 | 2001-10-30 | Raj Kumar Jain | High-speed sense amplifier |
| US6906169B2 (en) * | 2001-05-25 | 2005-06-14 | United Biomedical, Inc. | Immunogenic peptide composition comprising measles virus Fprotein Thelper cell epitope (MUFThl-16) and N-terminus of β-amyloid peptide |
-
2003
- 2003-04-07 JP JP2003586180A patent/JP4662719B2/ja not_active Expired - Fee Related
- 2003-04-07 PL PL373450A patent/PL209696B1/pl unknown
- 2003-04-07 ES ES03711746T patent/ES2368907T3/es not_active Expired - Lifetime
- 2003-04-07 MX MXPA04010255A patent/MXPA04010255A/es unknown
- 2003-04-07 CN CNB038088584A patent/CN100360555C/zh not_active Expired - Fee Related
- 2003-04-07 NZ NZ536064A patent/NZ536064A/en not_active IP Right Cessation
- 2003-04-07 EP EP03711746A patent/EP1497321B1/en not_active Expired - Lifetime
- 2003-04-07 WO PCT/CA2003/000502 patent/WO2003089460A1/en not_active Ceased
- 2003-04-07 IL IL16464303A patent/IL164643A0/xx unknown
- 2003-04-07 SG SG2006073324A patent/SG173214A1/en unknown
- 2003-04-07 EP EP10182139.5A patent/EP2330113B1/en not_active Expired - Lifetime
- 2003-04-07 AU AU2003218560A patent/AU2003218560B2/en not_active Ceased
- 2003-04-07 CA CA2481952A patent/CA2481952C/en not_active Expired - Fee Related
- 2003-04-07 KR KR1020047016794A patent/KR100994748B1/ko not_active Expired - Fee Related
- 2003-04-07 AT AT03711746T patent/ATE514707T1/de not_active IP Right Cessation
- 2003-04-10 US US10/411,544 patent/US20030232758A1/en not_active Abandoned
-
2004
- 2004-10-17 IL IL164643A patent/IL164643A/en not_active IP Right Cessation
- 2004-11-01 ZA ZA2004/08811A patent/ZA200408811B/en unknown
- 2004-11-18 NO NO20045021A patent/NO335192B1/no not_active IP Right Cessation
-
2005
- 2005-07-13 US US11/180,225 patent/US20090041771A1/en not_active Abandoned
-
2009
- 2009-01-15 IL IL196532A patent/IL196532A/en not_active IP Right Cessation
- 2009-10-30 JP JP2009251464A patent/JP5345920B2/ja not_active Expired - Fee Related
-
2012
- 2012-03-29 US US13/434,205 patent/US20120315321A1/en not_active Abandoned
- 2012-11-13 JP JP2012249078A patent/JP2013075898A/ja not_active Withdrawn
-
2013
- 2013-11-07 NO NO20131483A patent/NO20131483L/no not_active Application Discontinuation
-
2014
- 2014-04-07 US US14/246,830 patent/US20140212481A1/en not_active Abandoned
-
2016
- 2016-06-17 US US15/186,049 patent/US20160297876A1/en not_active Abandoned
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