JP2006505502A5 - - Google Patents

Download PDF

Info

Publication number
JP2006505502A5
JP2006505502A5 JP2003586180A JP2003586180A JP2006505502A5 JP 2006505502 A5 JP2006505502 A5 JP 2006505502A5 JP 2003586180 A JP2003586180 A JP 2003586180A JP 2003586180 A JP2003586180 A JP 2003586180A JP 2006505502 A5 JP2006505502 A5 JP 2006505502A5
Authority
JP
Japan
Prior art keywords
seq
composition
peptide
amino acid
antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2003586180A
Other languages
English (en)
Japanese (ja)
Other versions
JP4662719B2 (ja
JP2006505502A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/CA2003/000502 external-priority patent/WO2003089460A1/en
Publication of JP2006505502A publication Critical patent/JP2006505502A/ja
Publication of JP2006505502A5 publication Critical patent/JP2006505502A5/ja
Application granted granted Critical
Publication of JP4662719B2 publication Critical patent/JP4662719B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP2003586180A 2002-04-19 2003-04-07 アルツハイマー病の処置のための免疫学的方法および組成物 Expired - Fee Related JP4662719B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37391402P 2002-04-19 2002-04-19
PCT/CA2003/000502 WO2003089460A1 (en) 2002-04-19 2003-04-07 Immunological methods and compositions for the treatment of alzheimer's disease

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2009251464A Division JP5345920B2 (ja) 2002-04-19 2009-10-30 アルツハイマー病の処置のための免疫学的方法および組成物

Publications (3)

Publication Number Publication Date
JP2006505502A JP2006505502A (ja) 2006-02-16
JP2006505502A5 true JP2006505502A5 (https=) 2006-06-01
JP4662719B2 JP4662719B2 (ja) 2011-03-30

Family

ID=29251102

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2003586180A Expired - Fee Related JP4662719B2 (ja) 2002-04-19 2003-04-07 アルツハイマー病の処置のための免疫学的方法および組成物
JP2009251464A Expired - Fee Related JP5345920B2 (ja) 2002-04-19 2009-10-30 アルツハイマー病の処置のための免疫学的方法および組成物
JP2012249078A Withdrawn JP2013075898A (ja) 2002-04-19 2012-11-13 アルツハイマー病の処置のための免疫学的方法および組成物

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2009251464A Expired - Fee Related JP5345920B2 (ja) 2002-04-19 2009-10-30 アルツハイマー病の処置のための免疫学的方法および組成物
JP2012249078A Withdrawn JP2013075898A (ja) 2002-04-19 2012-11-13 アルツハイマー病の処置のための免疫学的方法および組成物

Country Status (17)

Country Link
US (5) US20030232758A1 (https=)
EP (2) EP1497321B1 (https=)
JP (3) JP4662719B2 (https=)
KR (1) KR100994748B1 (https=)
CN (1) CN100360555C (https=)
AT (1) ATE514707T1 (https=)
AU (1) AU2003218560B2 (https=)
CA (1) CA2481952C (https=)
ES (1) ES2368907T3 (https=)
IL (3) IL164643A0 (https=)
MX (1) MXPA04010255A (https=)
NO (2) NO335192B1 (https=)
NZ (1) NZ536064A (https=)
PL (1) PL209696B1 (https=)
SG (1) SG173214A1 (https=)
WO (1) WO2003089460A1 (https=)
ZA (1) ZA200408811B (https=)

Families Citing this family (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2414772C (en) 2000-07-07 2011-06-28 Jan Naslund Prevention and treatment of alzheimer's disease
CA2504349A1 (en) * 2001-11-02 2003-05-15 Diagenics International Corporation Monoclonal antibodies specific for beta-amyloid
US20050106626A1 (en) * 2002-10-20 2005-05-19 George Pieczenik Ligand binding of amyloid peptide protein epitope
DE10303974A1 (de) 2003-01-31 2004-08-05 Abbott Gmbh & Co. Kg Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung
SE0401601D0 (sv) 2004-06-21 2004-06-21 Bioarctic Neuroscience Ab Protofibril specific antibodies and uses thereof
US8193250B2 (en) 2004-10-22 2012-06-05 Mount Sinai School Of Medicine Compositions and methods for treating alzheimer's disease and related disorders and promoting a healthy nervous system
US20090123952A1 (en) * 2004-11-12 2009-05-14 Pfizer, Inc. Method of Measuring Amyloid-Beta Peptides
US8691224B2 (en) 2005-11-30 2014-04-08 Abbvie Inc. Anti-Aβ globulomer 5F7 antibodies
HRP20140240T4 (hr) 2005-11-30 2017-02-24 Abbvie Inc. Monoklonalna antitijela protiv amiloidnih beta proteina i njihova upotreba
EP1959996A2 (en) 2005-12-12 2008-08-27 AC Immune S.A. Monoclonal antibody
JP5097695B2 (ja) 2006-02-22 2012-12-12 株式会社林原 抗アミロイドβペプチド抗体産生誘導用のペプチドワクチン
RU2429244C2 (ru) 2006-03-23 2011-09-20 Байоарктик Ньюросайенс Аб Улучшенные селективные в отношении протофибрилл антитела и их применение
DE112007001030T5 (de) * 2006-04-28 2009-02-26 Kagoshima University Amyloid-ß-Fibrillogenese-inhibierendes Peptid
EP2046833B9 (en) 2006-07-14 2014-02-19 AC Immune S.A. Humanized antibody against amyloid beta
US8455626B2 (en) 2006-11-30 2013-06-04 Abbott Laboratories Aβ conformer selective anti-aβ globulomer monoclonal antibodies
WO2008143708A2 (en) * 2006-12-07 2008-11-27 Mayo Foundation For Medical Education And Research Methods and materials related to anti-amyloid antibodies
HRP20140049T1 (hr) * 2007-01-05 2014-02-28 University Of Zürich Anti beta-amiloid antitijela i njihova upotreba
US8895004B2 (en) 2007-02-27 2014-11-25 AbbVie Deutschland GmbH & Co. KG Method for the treatment of amyloidoses
JP5930573B2 (ja) 2007-03-01 2016-06-15 プロビオドルグ エージー グルタミニルシクラーゼ阻害剤の新規使用
EP2142514B1 (en) 2007-04-18 2014-12-24 Probiodrug AG Thiourea derivatives as glutaminyl cyclase inhibitors
US8048420B2 (en) 2007-06-12 2011-11-01 Ac Immune S.A. Monoclonal antibody
US8613923B2 (en) 2007-06-12 2013-12-24 Ac Immune S.A. Monoclonal antibody
AU2008311367B2 (en) 2007-10-05 2014-11-13 Ac Immune S.A. Use of anti-amyloid beta antibody in ocular diseases
WO2010024927A2 (en) * 2008-08-28 2010-03-04 The Research Foundation Of State University Of New York Treatment of amyloidoses using myelin basic protein and fragments thereof
US8912145B2 (en) 2008-11-28 2014-12-16 Hokko Chemical Industry Co., Ltd. Vaccine composition for prophylaxis and/or therapy of Alzheimer's disease
WO2010061899A1 (ja) * 2008-11-28 2010-06-03 北興化学工業株式会社 ワクチンを蓄積する形質転換ダイズ植物およびその利用
CN101797493B (zh) * 2009-02-06 2014-05-21 上海抗体药物国家工程研究中心有限公司 一种在反应釜中制备亲和层析介质的方法
CN101486768B (zh) * 2009-02-25 2012-05-30 吉林大学 一种用于治疗阿尔茨海默氏病的抗原蛋白及蛋白基因
WO2010124028A2 (en) * 2009-04-21 2010-10-28 Vasylyev Sergiy V Light collection and illumination systems employing planar waveguide
JP5934645B2 (ja) 2009-09-11 2016-06-15 プロビオドルグ エージー グルタミニルシクラーゼ阻害剤としてのヘテロ環式誘導体
JP6026284B2 (ja) 2010-03-03 2016-11-16 プロビオドルグ エージー グルタミニルシクラーゼの阻害剤
NZ602312A (en) 2010-03-10 2014-02-28 Probiodrug Ag Heterocyclic inhibitors of glutaminyl cyclase (qc, ec 2.3.2.5)
US8987419B2 (en) 2010-04-15 2015-03-24 AbbVie Deutschland GmbH & Co. KG Amyloid-beta binding proteins
WO2011131748A2 (en) 2010-04-21 2011-10-27 Probiodrug Ag Novel inhibitors
EP2598882B1 (en) 2010-07-30 2017-07-26 AC Immune S.A. Safe and functional humanized antibodies for use in treating an amyloidosis
EP3533803B1 (en) 2010-08-14 2021-10-27 AbbVie Inc. Anti-amyloid-beta antibodies
US20120328605A1 (en) * 2010-10-27 2012-12-27 Daniel Larocque Compositions and uses
EP2686313B1 (en) 2011-03-16 2016-02-03 Probiodrug AG Benzimidazole derivatives as inhibitors of glutaminyl cyclase
DE102011057019A1 (de) * 2011-12-23 2013-06-27 Forschungszentrum Jülich GmbH Standard zur Quantifizierung von pathogenen Aggregaten aus körpereigenen Proteinen
CA2848994A1 (en) * 2012-01-20 2013-07-25 Ananth Annapragada Methods and compositions for objectively characterizing medical images
US9534048B2 (en) * 2012-08-24 2017-01-03 University Health Network Antibodies to TTR and methods of use
US9475866B2 (en) * 2012-09-12 2016-10-25 Neurimmune Holding Ag Human islet amyloid polypeptide (hIAPP) specific antibodies and uses thereof
SMT202000340T1 (it) 2012-10-15 2020-07-08 Medimmune Ltd Anticorpi contro il beta amiloide
US10195257B2 (en) 2013-07-28 2019-02-05 Qantu Therapeutics, Inc. Vaccine formulations comprising quillaja desacylsaponins and beta amyloid peptides or tau protein to induce a Th2 immune response
FI3137094T3 (fi) 2014-04-29 2023-03-20 Advantage Therapeutics Inc Alzheimerin taudin (ad) hoitaminen ja ehkäiseminen
WO2016005466A2 (en) 2014-07-10 2016-01-14 Bioarctic Neuroscience Ab IMPROVED Aß PROTOFIBRIL BINDING ANTIBODIES
MA41115A (fr) 2014-12-02 2017-10-10 Biogen Int Neuroscience Gmbh Procédé de traitement de la maladie d'alzheimer
AU2016353553B2 (en) * 2015-11-09 2022-01-20 The University Of British Columbia Amyloid beta epitopes and antibodies thereto
WO2017098516A1 (en) * 2015-12-10 2017-06-15 The National Institute for Biotechnology in the Negev Ltd. VARIANTS OF AMYLOID beta-PROTEIN PRECURSOR INHIBITOR DOMAIN
DK3425390T3 (da) * 2016-11-25 2021-02-15 Genuv Inc Sammensætning til fremme af differentiering og beskyttelse af neurale stamceller og fremgangsmåde til induktion af neural regenerering ved anvendelse heraf
CN111201030B (zh) 2017-07-25 2024-11-01 真和制药有限公司 通过阻断tim-3和其配体的相互作用治疗癌症
CN118370815A (zh) 2017-08-22 2024-07-23 渤健马萨诸塞州股份有限公司 含有抗β淀粉样蛋白抗体的药物组合物
ES2812698T3 (es) 2017-09-29 2021-03-18 Probiodrug Ag Inhibidores de glutaminil ciclasa
CN111787942B (zh) 2017-10-25 2024-03-29 杨森制药公司 磷酸化Tau肽的组合物及其用途
WO2019218079A1 (en) * 2018-05-18 2019-11-21 Universite Laval Use of nod2 agonist for the treatment, prophylaxis and/or delay of the onset of multiple sclerosis and alzheimer's disease
WO2020160156A2 (en) 2019-01-30 2020-08-06 Immutics, Inc. Anti-gal3 antibodies and uses thereof
MY206596A (en) * 2019-02-08 2024-12-25 Janssen Pharmaceuticals Inc Method of safe administration of phosphorylated tau peptide vaccine
JP7505713B2 (ja) 2019-02-22 2024-06-25 ロヨラ メリーマウント ユニバーシティ アミロイドペプチドバリアント
JOP20210284A1 (ar) 2019-04-24 2023-01-30 Janssen Pharmaceuticals Inc الإعطاء غير المتجانس للقاحات تاو
CN115066610A (zh) * 2020-02-05 2022-09-16 住友制药株式会社 用于tau病变和痴呆相关疾病的确定试剂和确定方法
TW202144387A (zh) * 2020-02-11 2021-12-01 美商聯合生物醫學公司 針對胰島澱粉樣多肽（iapp）的胜肽免疫原及其預防和治療與聚集iapp相關疾病的製劑
CA3183431A1 (en) * 2020-05-15 2021-11-18 Vib Vzw Means and methods for the treatment of pathological aggregation
EP4157338A4 (en) 2020-05-26 2024-11-13 TrueBinding, Inc. METHOD FOR TREATING INFLAMMATORY DISEASES BY GALECTIN-3 BLOCKING
WO2023159970A1 (zh) * 2022-02-28 2023-08-31 安域生物科技杭州有限公司 基于β-淀粉样蛋白修饰的抗原多肽及其应用
CN115786260B (zh) * 2022-12-26 2024-08-20 海南大学 Aβ42-hIAPP共寡聚化物诱导的AD脑类器官病理模型方法

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4235877A (en) 1979-06-27 1980-11-25 Merck & Co., Inc. Liposome particle containing viral or bacterial antigenic subunit
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4666829A (en) * 1985-05-15 1987-05-19 University Of California Polypeptide marker for Alzheimer's disease and its use for diagnosis
GB8823869D0 (en) 1988-10-12 1988-11-16 Medical Res Council Production of antibodies
US5814318A (en) 1990-08-29 1998-09-29 Genpharm International Inc. Transgenic non-human animals for producing heterologous antibodies
US5874299A (en) 1990-08-29 1999-02-23 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
US5770429A (en) 1990-08-29 1998-06-23 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
CA2138997C (en) 1992-06-25 2003-06-03 Jean-Paul Prieels Vaccine composition containing adjuvants
US5766846A (en) * 1992-07-10 1998-06-16 Athena Neurosciences Methods of screening for compounds which inhibit soluble β-amyloid peptide production
US5840294A (en) 1993-03-29 1998-11-24 Queen's University At Kingston Method for treating amyloidosis
US5759551A (en) 1993-04-27 1998-06-02 United Biomedical, Inc. Immunogenic LHRH peptide constructs and synthetic universal immune stimulators for vaccines
WO1994025060A1 (en) * 1993-04-27 1994-11-10 Ladd Anna E Immunogenic lhrh peptide constructs and synthetic universal immune stimulators for vaccines
US5744144A (en) 1993-07-30 1998-04-28 University Of Pittsburgh University Patent Committee Policy And Procedures Synthetic multiple tandem repeat mucin and mucin-like peptides, and uses thereof
GB9326253D0 (en) 1993-12-23 1994-02-23 Smithkline Beecham Biolog Vaccines
UA56132C2 (uk) 1995-04-25 2003-05-15 Смітклайн Бічем Байолоджікалс С.А. Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини
AU6728396A (en) 1995-08-17 1997-03-12 Ontario Cancer Institute, The Protein fibril assembly assay
US7964192B1 (en) * 1997-12-02 2011-06-21 Janssen Alzheimer Immunotherapy Prevention and treatment of amyloidgenic disease
US6750324B1 (en) * 1997-12-02 2004-06-15 Neuralab Limited Humanized and chimeric N-terminal amyloid beta-antibodies
AU2001270377A1 (en) 2000-06-20 2002-01-02 The Governing Council Of The University Of Toronto Transgenic animal model of neurodegenerative disorders
US6310810B1 (en) 2000-07-14 2001-10-30 Raj Kumar Jain High-speed sense amplifier
US6906169B2 (en) * 2001-05-25 2005-06-14 United Biomedical, Inc. Immunogenic peptide composition comprising measles virus Fprotein Thelper cell epitope (MUFThl-16) and N-terminus of β-amyloid peptide

Similar Documents

Publication Publication Date Title
JP2006505502A5 (https=)
CN1826354B (zh) 预防和治疗阿尔茨海默病(ad)的方法
DK1546734T3 (en) MONOCLONAL ANTIBODIES AGAINST N-11-TRUNCATED AMYLOID BETA, COMPOSITIONS, PROCEDURES AND APPLICATIONS
JP5179866B2 (ja) アルツハイマー病の予防および治療方法
JP2010065046A5 (https=)
WO2005023870A1 (ja) ＴＧＦ－β活性化制御領域の切断面を認識する抗体
AU2009257170A1 (en) Compounds for treating symptoms associated with Parkinson's disease
CN101481415B (zh) 一种新型prrs病毒受体及该受体的阻断抑制剂
JP2007522119A5 (https=)
JPH03501968A (ja) オリゴペプチド、及びａｉｄｓまたはａｒｃの診断及びワクチン接種を目的としたそれらの用途
JP2007300856A (ja) アミロイドタンパク質模倣物
JP2022511995A5 (https=)
CN100467484C (zh) Sars早期诊断方法及试剂盒
JP2008515390A5 (https=)
JPH05230097A (ja) Ｂ型肝炎ウイルスのＨＢｃ抗原由来の合成ペプチド、このウイルスによる感染を検出すること及び抗Ｂ型肝炎ワクチンのための該ペプチドの使用
CN100393743C (zh) Sars早期诊断的多肽及试剂盒
CN118598973A (zh) 一种组蛋白h3多肽及组蛋白h3抗体
Viter et al. Analysis of antigenic structure of Potato Virus M Ukrainian strains
JPH0987297A (ja) ヘリコバクター・ピロリ菌ウレアーゼ蛋白由来の人工抗原及びその人工抗原によって誘発された抗体
Chagnaud et al. Identification of epitopes recognized by monoclonal antibodies directed against HTLV-I envelope surface glycoprotein using peptide phage display
JPH03128393A (ja) ヒトリンパ栄養性ウィルスの処理及び診断
Paantjens et al. Identification of Allo-and Auto-Antibodies after Lung Transplantation
JP2005104975A (ja) 抗体の用途
AU2006203495A1 (en) Mimotopes
JP2007537985A5 (https=)