JP2006503077A - チエノピロール誘導体を製造するための方法および中間体 - Google Patents
チエノピロール誘導体を製造するための方法および中間体 Download PDFInfo
- Publication number
- JP2006503077A JP2006503077A JP2004540938A JP2004540938A JP2006503077A JP 2006503077 A JP2006503077 A JP 2006503077A JP 2004540938 A JP2004540938 A JP 2004540938A JP 2004540938 A JP2004540938 A JP 2004540938A JP 2006503077 A JP2006503077 A JP 2006503077A
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- formula
- carbamoyl
- compound
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 0 *c1cc([s]c(*)c2*)c2[n]1 Chemical compound *c1cc([s]c(*)c2*)c2[n]1 0.000 description 5
- MAAYJKQLJPUKTK-UHFFFAOYSA-N CC(C)(C)OC(Nc1c[s]c(Cl)c1Cl)=O Chemical compound CC(C)(C)OC(Nc1c[s]c(Cl)c1Cl)=O MAAYJKQLJPUKTK-UHFFFAOYSA-N 0.000 description 2
- YTRPEPWHVNGJIF-UHFFFAOYSA-N CC(C)(C)OC(Nc1c(C=O)[s]c(Cl)c1Cl)=O Chemical compound CC(C)(C)OC(Nc1c(C=O)[s]c(Cl)c1Cl)=O YTRPEPWHVNGJIF-UHFFFAOYSA-N 0.000 description 1
- BXCIVCFRSLPEFH-UHFFFAOYSA-N OC(c1c[s]c(Cl)c1Cl)=O Chemical compound OC(c1c[s]c(Cl)c1Cl)=O BXCIVCFRSLPEFH-UHFFFAOYSA-N 0.000 description 1
- JPKMAPPQOGAGBO-UHFFFAOYSA-N ONc1c[nH]cc1 Chemical compound ONc1c[nH]cc1 JPKMAPPQOGAGBO-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/36—Nitrogen atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0222909.4A GB0222909D0 (en) | 2002-10-03 | 2002-10-03 | Novel process and intermediates |
| PCT/GB2003/004211 WO2004031193A1 (en) | 2002-10-03 | 2003-09-29 | Process and intermediates for the preparation of thienopyrrole derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006503077A true JP2006503077A (ja) | 2006-01-26 |
| JP2006503077A5 JP2006503077A5 (https=) | 2006-08-10 |
Family
ID=9945217
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004540938A Withdrawn JP2006503077A (ja) | 2002-10-03 | 2003-09-29 | チエノピロール誘導体を製造するための方法および中間体 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US7307174B2 (https=) |
| EP (1) | EP1549653A1 (https=) |
| JP (1) | JP2006503077A (https=) |
| KR (1) | KR20050061490A (https=) |
| CN (1) | CN1688588A (https=) |
| AU (1) | AU2003267656A1 (https=) |
| BR (1) | BR0314312A (https=) |
| CA (1) | CA2498843A1 (https=) |
| GB (1) | GB0222909D0 (https=) |
| MX (1) | MXPA05003387A (https=) |
| NO (1) | NO20051047L (https=) |
| WO (1) | WO2004031193A1 (https=) |
| ZA (1) | ZA200501742B (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0205165D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0205170D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0205175D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0205176D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0205166D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0205162D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0222912D0 (en) | 2002-10-03 | 2002-11-13 | Astrazeneca Ab | Novel process and intermediates |
| GB0321003D0 (en) * | 2003-09-09 | 2003-10-08 | Angeletti P Ist Richerche Bio | Compounds, compositions and uses |
| JP2007517056A (ja) | 2003-12-29 | 2007-06-28 | セプラコア インコーポレーテッド | ピロール及びピラゾールｄａａｏ阻害剤 |
| US20070203111A1 (en) | 2006-01-06 | 2007-08-30 | Sepracor Inc. | Cycloalkylamines as monoamine reuptake inhibitors |
| NZ569608A (en) | 2006-01-06 | 2011-09-30 | Sepracor Inc | Tetralone-based monoamine reuptake inhibitors |
| US7884124B2 (en) | 2006-06-30 | 2011-02-08 | Sepracor Inc. | Fluoro-substituted inhibitors of D-amino acid oxidase |
| MX2009007395A (es) * | 2007-01-09 | 2009-07-17 | Bayer Schering Pharma Ag | Marcacion radioactiva por fluoracion de aziridinas. |
| US7902252B2 (en) | 2007-01-18 | 2011-03-08 | Sepracor, Inc. | Inhibitors of D-amino acid oxidase |
| CA2688493C (en) | 2007-05-31 | 2016-04-19 | Sepracor Inc. | Phenyl substituted cycloalkylamines as monoamine reuptake inhibitors |
| CN106588868A (zh) * | 2016-11-16 | 2017-04-26 | 武汉理工大学 | 一种2‑溴‑3‑噻吩甲酸中间体的合成方法 |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU364613A1 (ru) | 1970-11-27 | 1972-12-28 | Всесоюзный научно исследовательский химико фармацевтический институт имени С. Орджоникидзе | Способ получения производных 2-аминотиено- |
| GB9302622D0 (en) | 1993-02-10 | 1993-03-24 | Wellcome Found | Heteroaromatic compounds |
| DE60007592T2 (de) | 1999-09-30 | 2004-09-16 | Pfizer Products Inc., Groton | Bicyclische Pyrrolylamide als Glycogenphosphorylase-Inhibitoren |
| AU778042B2 (en) | 1999-10-19 | 2004-11-11 | Merck & Co., Inc. | Tyrosine kinase inhibitors |
| SE9903998D0 (sv) | 1999-11-03 | 1999-11-03 | Astra Ab | New compounds |
| JP2001294572A (ja) * | 2000-02-09 | 2001-10-23 | Dai Ichi Seiyaku Co Ltd | 新規スルホニル誘導体 |
| EP1136071A3 (en) | 2000-03-22 | 2003-03-26 | Pfizer Products Inc. | Use of glycogen phosphorylase inhibitors |
| GB0017676D0 (en) | 2000-07-19 | 2000-09-06 | Angeletti P Ist Richerche Bio | Inhibitors of viral polymerase |
| GB0021831D0 (en) | 2000-09-06 | 2000-10-18 | Astrazeneca Ab | Chemical compounds |
| MXPA03000966A (es) | 2002-02-28 | 2003-09-04 | Pfizer Prod Inc | Agentes antidiabeticos. |
| GB0205170D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0205162D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0205166D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0205175D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0205176D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0205165D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| JPWO2003091213A1 (ja) | 2002-04-25 | 2005-09-02 | アステラス製薬株式会社 | 新規なアミド誘導体又はその塩 |
| EP1543011B1 (en) | 2002-09-06 | 2006-05-03 | Janssen Pharmaceutica N.V. | Thienopyrrolyl and furanopyrrolyl compounds and their use as histamine h4 receptor ligands |
| GB0222912D0 (en) | 2002-10-03 | 2002-11-13 | Astrazeneca Ab | Novel process and intermediates |
| WO2004041780A2 (en) | 2002-11-07 | 2004-05-21 | Pfizer Products Inc. | N-(indole-2-carbonyl) amides as anti-diabetic agents |
| US7098235B2 (en) | 2002-11-14 | 2006-08-29 | Bristol-Myers Squibb Co. | Triglyceride and triglyceride-like prodrugs of glycogen phosphorylase inhibiting compounds |
| JP2004196702A (ja) | 2002-12-18 | 2004-07-15 | Yamanouchi Pharmaceut Co Ltd | 新規なアミド誘導体又はその塩 |
| JP4109288B2 (ja) | 2002-12-25 | 2008-07-02 | 第一三共株式会社 | ジアミン誘導体 |
| BRPI0409465A (pt) | 2003-04-17 | 2006-05-02 | Pfizer Prod Inc | derivados de carboxamida como agentes antidiabéticos |
| BRPI0409952A (pt) | 2003-04-30 | 2006-04-25 | Pfizer Prod Inc | agentes anti-diabéticos |
| WO2004113345A1 (ja) | 2003-06-20 | 2004-12-29 | Japan Tobacco Inc. | 縮合ピロール化合物及びその医薬用途 |
| GB0318463D0 (en) | 2003-08-07 | 2003-09-10 | Astrazeneca Ab | Chemical compounds |
| GB0318464D0 (en) | 2003-08-07 | 2003-09-10 | Astrazeneca Ab | Chemical compounds |
| GB0319690D0 (en) | 2003-08-22 | 2003-09-24 | Astrazeneca Ab | Chemical compounds |
| GB0319759D0 (en) | 2003-08-22 | 2003-09-24 | Astrazeneca Ab | Chemical compounds |
| WO2005020986A1 (en) | 2003-08-29 | 2005-03-10 | Astrazeneca Ab | Heterocyclic amide derivatives which posses glycogen phosphorylase inhibitory activity |
| WO2005020985A1 (en) | 2003-08-29 | 2005-03-10 | Astrazeneca Ab | Indolamide derivatives which possess glycogen phosphorylase inhibitory activity |
| GB0320422D0 (en) | 2003-08-30 | 2003-10-01 | Astrazeneca Ab | Chemical compounds |
-
2002
- 2002-10-03 GB GBGB0222909.4A patent/GB0222909D0/en not_active Ceased
-
2003
- 2003-09-29 CN CNA038237369A patent/CN1688588A/zh active Pending
- 2003-09-29 EP EP03748348A patent/EP1549653A1/en not_active Withdrawn
- 2003-09-29 BR BR0314312-0A patent/BR0314312A/pt not_active Application Discontinuation
- 2003-09-29 CA CA002498843A patent/CA2498843A1/en not_active Abandoned
- 2003-09-29 AU AU2003267656A patent/AU2003267656A1/en not_active Abandoned
- 2003-09-29 JP JP2004540938A patent/JP2006503077A/ja not_active Withdrawn
- 2003-09-29 KR KR1020057005374A patent/KR20050061490A/ko not_active Withdrawn
- 2003-09-29 US US10/528,612 patent/US7307174B2/en not_active Expired - Fee Related
- 2003-09-29 WO PCT/GB2003/004211 patent/WO2004031193A1/en not_active Ceased
- 2003-09-29 MX MXPA05003387A patent/MXPA05003387A/es not_active Application Discontinuation
-
2005
- 2005-02-25 NO NO20051047A patent/NO20051047L/no unknown
-
2006
- 2006-01-19 ZA ZA200501742A patent/ZA200501742B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2004031193A1 (en) | 2004-04-15 |
| MXPA05003387A (es) | 2005-06-22 |
| US7307174B2 (en) | 2007-12-11 |
| NO20051047L (no) | 2005-04-28 |
| KR20050061490A (ko) | 2005-06-22 |
| EP1549653A1 (en) | 2005-07-06 |
| US20050272938A1 (en) | 2005-12-08 |
| CA2498843A1 (en) | 2004-04-15 |
| GB0222909D0 (en) | 2002-11-13 |
| AU2003267656A1 (en) | 2004-04-23 |
| BR0314312A (pt) | 2005-07-26 |
| CN1688588A (zh) | 2005-10-26 |
| ZA200501742B (en) | 2006-03-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20060622 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20060622 |
|
| A761 | Written withdrawal of application |
Free format text: JAPANESE INTERMEDIATE CODE: A761 Effective date: 20090319 |