BR0314312A - Processo para preparar um composto, e, composto - Google Patents

Processo para preparar um composto, e, composto

Info

Publication number
BR0314312A
BR0314312A BR0314312-0A BR0314312A BR0314312A BR 0314312 A BR0314312 A BR 0314312A BR 0314312 A BR0314312 A BR 0314312A BR 0314312 A BR0314312 A BR 0314312A
Authority
BR
Brazil
Prior art keywords
compound
preparing
formula
protecting group
intermediates
Prior art date
Application number
BR0314312-0A
Other languages
English (en)
Inventor
Michael Butters
Paul Schofield
Andrew Stocker
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of BR0314312A publication Critical patent/BR0314312A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
    • C07D333/36—Nitrogen atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)

Abstract

"PROCESSO PARA PREPARAR UM COMPOSTO, E, COMPOSTO". Processo e Intermediários novos. Processo para preparar um composto de fórmula (I) onde R^ 4^ e R^ 5^ são como definidos no relatório; e R^ 6^ é hidrogênio ou um grupo de proteção, em que o processo compreende ciclização de um composto de fórmula (II) onde R^ 4^ R^ 5^ e R^ 6^ são como definidos em relação à fórmula (I), e R^ 7^ é um grupo de proteção de nitrogênio, e remover o grupo R^ 7^, e desde então se desejado, remover qualquer grupo de proteção R^ 6^. Intermediários novos e o uso desses na formação de compostos farmacêuticos é também descrito e reivindicado.
BR0314312-0A 2002-10-03 2003-09-29 Processo para preparar um composto, e, composto BR0314312A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0222909.4A GB0222909D0 (en) 2002-10-03 2002-10-03 Novel process and intermediates
PCT/GB2003/004211 WO2004031193A1 (en) 2002-10-03 2003-09-29 Process and intermediates for the preparation of thienopyrrole derivatives

Publications (1)

Publication Number Publication Date
BR0314312A true BR0314312A (pt) 2005-07-26

Family

ID=9945217

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0314312-0A BR0314312A (pt) 2002-10-03 2003-09-29 Processo para preparar um composto, e, composto

Country Status (13)

Country Link
US (1) US7307174B2 (pt)
EP (1) EP1549653A1 (pt)
JP (1) JP2006503077A (pt)
KR (1) KR20050061490A (pt)
CN (1) CN1688588A (pt)
AU (1) AU2003267656A1 (pt)
BR (1) BR0314312A (pt)
CA (1) CA2498843A1 (pt)
GB (1) GB0222909D0 (pt)
MX (1) MXPA05003387A (pt)
NO (1) NO20051047L (pt)
WO (1) WO2004031193A1 (pt)
ZA (1) ZA200501742B (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0205166D0 (en) 2002-03-06 2002-04-17 Astrazeneca Ab Chemical compounds
GB0205165D0 (en) 2002-03-06 2002-04-17 Astrazeneca Ab Chemical compounds
GB0205162D0 (en) 2002-03-06 2002-04-17 Astrazeneca Ab Chemical compounds
GB0205175D0 (en) 2002-03-06 2002-04-17 Astrazeneca Ab Chemical compounds
GB0205176D0 (en) 2002-03-06 2002-04-17 Astrazeneca Ab Chemical compounds
GB0205170D0 (en) 2002-03-06 2002-04-17 Astrazeneca Ab Chemical compounds
GB0222912D0 (en) 2002-10-03 2002-11-13 Astrazeneca Ab Novel process and intermediates
GB0321003D0 (en) * 2003-09-09 2003-10-08 Angeletti P Ist Richerche Bio Compounds, compositions and uses
CZ2006427A3 (cs) 2003-12-29 2006-11-15 Sepracor Inc. Pyrrolové a pyrazolové inhibitory DAAO
ES2566479T3 (es) 2006-01-06 2016-04-13 Sunovion Pharmaceuticals Inc. Inhibidores de reabsorción de monoamina con base en tetralona
US20070203111A1 (en) 2006-01-06 2007-08-30 Sepracor Inc. Cycloalkylamines as monoamine reuptake inhibitors
US7884124B2 (en) 2006-06-30 2011-02-08 Sepracor Inc. Fluoro-substituted inhibitors of D-amino acid oxidase
WO2008083729A1 (en) * 2007-01-09 2008-07-17 Bayer Schering Pharma Aktiengesellschaft Radiolabelling via fluorination of aziridines
US7902252B2 (en) 2007-01-18 2011-03-08 Sepracor, Inc. Inhibitors of D-amino acid oxidase
JP5420534B2 (ja) 2007-05-31 2014-02-19 サノビオン ファーマシューティカルズ インク モノアミン再取り込み阻害薬としてのフェニル置換シクロアルキルアミン
CN106588868A (zh) * 2016-11-16 2017-04-26 武汉理工大学 一种2‑溴‑3‑噻吩甲酸中间体的合成方法

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Publication number Priority date Publication date Assignee Title
SU364613A1 (ru) 1970-11-27 1972-12-28 Всесоюзный научно исследовательский химико фармацевтический институт имени С. Орджоникидзе Способ получения производных 2-аминотиено-
GB9302622D0 (en) * 1993-02-10 1993-03-24 Wellcome Found Heteroaromatic compounds
ES2211454T3 (es) 1999-09-30 2004-07-16 Pfizer Products Inc. Pirrolilamidas como inhibidores de la colageno fosforilasa.
ES2235970T3 (es) 1999-10-19 2005-07-16 MERCK & CO. INC. Inhibidores de tirosina quinasa.
SE9903998D0 (sv) 1999-11-03 1999-11-03 Astra Ab New compounds
JP2001294572A (ja) 2000-02-09 2001-10-23 Dai Ichi Seiyaku Co Ltd 新規スルホニル誘導体
EP1136071A3 (en) 2000-03-22 2003-03-26 Pfizer Products Inc. Use of glycogen phosphorylase inhibitors
GB0017676D0 (en) 2000-07-19 2000-09-06 Angeletti P Ist Richerche Bio Inhibitors of viral polymerase
GB0021831D0 (en) 2000-09-06 2000-10-18 Astrazeneca Ab Chemical compounds
MXPA03000966A (es) 2002-02-28 2003-09-04 Pfizer Prod Inc Agentes antidiabeticos.
GB0205165D0 (en) 2002-03-06 2002-04-17 Astrazeneca Ab Chemical compounds
GB0205166D0 (en) 2002-03-06 2002-04-17 Astrazeneca Ab Chemical compounds
GB0205162D0 (en) 2002-03-06 2002-04-17 Astrazeneca Ab Chemical compounds
GB0205175D0 (en) 2002-03-06 2002-04-17 Astrazeneca Ab Chemical compounds
GB0205176D0 (en) 2002-03-06 2002-04-17 Astrazeneca Ab Chemical compounds
GB0205170D0 (en) 2002-03-06 2002-04-17 Astrazeneca Ab Chemical compounds
AU2003227360A1 (en) 2002-04-25 2003-11-10 Yamanouchi Pharmaceutical Co., Ltd. Novel amide derivatives or salts thereof
AU2003272285A1 (en) 2002-09-06 2004-03-29 Janssen Pharmaceutica, N.V. Thienopyrrolyl and furanopyrrolyl compounds and their use as histamine h4 receptor ligands
GB0222912D0 (en) 2002-10-03 2002-11-13 Astrazeneca Ab Novel process and intermediates
CA2503727A1 (en) 2002-11-07 2004-05-21 Pfizer Products Inc. Anti-diabetic agents
US7098235B2 (en) 2002-11-14 2006-08-29 Bristol-Myers Squibb Co. Triglyceride and triglyceride-like prodrugs of glycogen phosphorylase inhibiting compounds
JP2004196702A (ja) 2002-12-18 2004-07-15 Yamanouchi Pharmaceut Co Ltd 新規なアミド誘導体又はその塩
KR20050110612A (ko) 2002-12-25 2005-11-23 다이이찌 세이야꾸 가부시기가이샤 디아민 유도체
MXPA05011176A (es) 2003-04-17 2005-12-14 Pfizer Prod Inc Derivados de carboxamida como agentes antidiabeticos.
MXPA05011702A (es) 2003-04-30 2006-01-23 Pfizer Prod Inc Agentes antidiabeticos.
WO2004113345A1 (ja) 2003-06-20 2004-12-29 Japan Tobacco Inc. 縮合ピロール化合物及びその医薬用途
GB0318463D0 (en) 2003-08-07 2003-09-10 Astrazeneca Ab Chemical compounds
GB0318464D0 (en) 2003-08-07 2003-09-10 Astrazeneca Ab Chemical compounds
GB0319759D0 (en) 2003-08-22 2003-09-24 Astrazeneca Ab Chemical compounds
GB0319690D0 (en) 2003-08-22 2003-09-24 Astrazeneca Ab Chemical compounds
WO2005020986A1 (en) 2003-08-29 2005-03-10 Astrazeneca Ab Heterocyclic amide derivatives which posses glycogen phosphorylase inhibitory activity
WO2005020985A1 (en) 2003-08-29 2005-03-10 Astrazeneca Ab Indolamide derivatives which possess glycogen phosphorylase inhibitory activity
GB0320422D0 (en) 2003-08-30 2003-10-01 Astrazeneca Ab Chemical compounds

Also Published As

Publication number Publication date
KR20050061490A (ko) 2005-06-22
EP1549653A1 (en) 2005-07-06
NO20051047L (no) 2005-04-28
AU2003267656A1 (en) 2004-04-23
ZA200501742B (en) 2006-03-29
GB0222909D0 (en) 2002-11-13
CN1688588A (zh) 2005-10-26
CA2498843A1 (en) 2004-04-15
US7307174B2 (en) 2007-12-11
US20050272938A1 (en) 2005-12-08
WO2004031193A1 (en) 2004-04-15
MXPA05003387A (es) 2005-06-22
JP2006503077A (ja) 2006-01-26

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]