DE60123911D1 - Verfahren zur Herstellung von Aryloctanoyl-amiden - Google Patents
Verfahren zur Herstellung von Aryloctanoyl-amidenInfo
- Publication number
- DE60123911D1 DE60123911D1 DE60123911T DE60123911T DE60123911D1 DE 60123911 D1 DE60123911 D1 DE 60123911D1 DE 60123911 T DE60123911 T DE 60123911T DE 60123911 T DE60123911 T DE 60123911T DE 60123911 D1 DE60123911 D1 DE 60123911D1
- Authority
- DE
- Germany
- Prior art keywords
- chem
- formula
- compounds
- removal
- reaction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
- C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/16—Preparation of optical isomers
- C07C231/18—Preparation of optical isomers by stereospecific synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH24422000 | 2000-12-14 | ||
CH24422000 | 2000-12-14 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60123911D1 true DE60123911D1 (de) | 2006-11-30 |
DE60123911T2 DE60123911T2 (de) | 2007-05-31 |
Family
ID=4569276
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60123911T Expired - Lifetime DE60123911T2 (de) | 2000-12-14 | 2001-12-06 | Verfahren zur Herstellung von Aryloctanoyl-amiden |
Country Status (8)
Country | Link |
---|---|
US (2) | US20020082302A1 (de) |
EP (1) | EP1215201B1 (de) |
AT (1) | ATE342887T1 (de) |
CY (1) | CY1107575T1 (de) |
DE (1) | DE60123911T2 (de) |
DK (1) | DK1215201T3 (de) |
ES (1) | ES2274847T3 (de) |
PT (1) | PT1215201E (de) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0212410D0 (en) * | 2002-05-29 | 2002-07-10 | Novartis Ag | Organic compounds |
WO2003103653A1 (en) * | 2002-06-11 | 2003-12-18 | Elan Pharmaceuticals, Inc. | Methods of treating alzheimer's disease using aryl alkanoic acid amides |
GB0327839D0 (en) * | 2003-12-01 | 2003-12-31 | Novartis Ag | Organic compounds |
GB0419361D0 (en) * | 2004-08-31 | 2004-10-06 | Novartis Ag | Organic compounds |
GB0511686D0 (en) * | 2005-06-08 | 2005-07-13 | Novartis Ag | Organic compounds |
GB0521083D0 (en) | 2005-10-17 | 2005-11-23 | Novartis Ag | Organic compounds |
GB2431646A (en) * | 2005-10-25 | 2007-05-02 | Novartis Ag | Alternative synthesis of aryl-octanoyl amide compounds |
GB2431643A (en) * | 2005-10-25 | 2007-05-02 | Novartis Ag | Synthesis of aryl-octanoyl amide compounds |
GB2431652A (en) * | 2005-10-25 | 2007-05-02 | Novartis Ag | Alternative synthesis of aryl-octanoyl amide compounds |
GB2431645A (en) * | 2005-10-25 | 2007-05-02 | Novartis Ag | Alternative synthesis of aryl-octanoyl amide compounds |
GB2431654A (en) * | 2005-10-25 | 2007-05-02 | Novartis Ag | Alternative synthesis of aryl-octanoyl amide compounds |
GB2431647A (en) * | 2005-10-25 | 2007-05-02 | Novartis Ag | Synthesis of aryl-octanoyl amide compounds |
GB2431651A (en) * | 2005-10-25 | 2007-05-02 | Novartis Ag | Synthesis of aryl-octanoyl amide compounds |
GB2431650A (en) * | 2005-10-25 | 2007-05-02 | Novartis Ag | Alternative synthesis of aryl-octanoyl amide compounds |
GB2431648A (en) * | 2005-10-25 | 2007-05-02 | Novartis Ag | Alternative synthesis of aryl-octanoyl amide compounds |
GB2431640A (en) * | 2005-10-25 | 2007-05-02 | Novartis Ag | Alternative synthesis of aryl-octanoyl amide compounds |
GB2431644A (en) * | 2005-10-25 | 2007-05-02 | Novartis Ag | Synthesis of aryl-octanoyl amide compounds |
GB0522789D0 (en) | 2005-11-08 | 2005-12-14 | Novartis Ag | Organic compounds |
EP2062874B1 (de) | 2007-11-20 | 2014-12-17 | KRKA, tovarna zdravil, d.d., Novo mesto | Verfahren und Zwischenprodukte für die Herstellung von Aliskiren |
EP2189442B1 (de) | 2008-11-20 | 2014-10-01 | Krka Tovarna Zdravil, D.D., Novo Mesto | Verfahren und Zwischenprodukte für die Herstellung von Aliskiren |
US8203005B2 (en) | 2009-10-29 | 2012-06-19 | Carbo Design Llc | Manufacturing process for enantiomerically pure 8-aryloctanoic acids as Aliskiren |
WO2011064790A1 (en) * | 2009-11-30 | 2011-06-03 | Avra Laboratories Pvt. Ltd | A novel process for making aliskiren, its novel intermediates and certain novel compounds |
US8703976B2 (en) | 2011-10-02 | 2014-04-22 | Milan Soukup | Manufacturing process for 8-aryloctanoic acids such as Aliskiren |
CN113546633B (zh) * | 2021-07-27 | 2022-07-01 | 云南大学 | 一种镨基磁性催化剂及其制备方法和应用 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MY119161A (en) * | 1994-04-18 | 2005-04-30 | Novartis Ag | Delta-amino-gamma-hydroxy-omega-aryl-alkanoic acid amides with enzyme especially renin inhibiting activities |
-
2001
- 2001-12-06 ES ES01128462T patent/ES2274847T3/es not_active Expired - Lifetime
- 2001-12-06 DE DE60123911T patent/DE60123911T2/de not_active Expired - Lifetime
- 2001-12-06 DK DK01128462T patent/DK1215201T3/da active
- 2001-12-06 AT AT01128462T patent/ATE342887T1/de active
- 2001-12-06 PT PT01128462T patent/PT1215201E/pt unknown
- 2001-12-06 EP EP01128462A patent/EP1215201B1/de not_active Expired - Lifetime
- 2001-12-14 US US10/014,400 patent/US20020082302A1/en not_active Abandoned
-
2003
- 2003-01-15 US US10/342,254 patent/US6670507B2/en not_active Expired - Fee Related
-
2006
- 2006-12-19 CY CY20061101815T patent/CY1107575T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP1215201A3 (de) | 2003-01-29 |
DK1215201T3 (da) | 2007-01-29 |
EP1215201A2 (de) | 2002-06-19 |
ES2274847T3 (es) | 2007-06-01 |
PT1215201E (pt) | 2007-02-28 |
US20020082302A1 (en) | 2002-06-27 |
CY1107575T1 (el) | 2013-03-13 |
US6670507B2 (en) | 2003-12-30 |
ATE342887T1 (de) | 2006-11-15 |
US20030176717A1 (en) | 2003-09-18 |
EP1215201B1 (de) | 2006-10-18 |
DE60123911T2 (de) | 2007-05-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |