JP2006503068A - １ｈ−イミダゾダイマー - Google Patents
１ｈ−イミダゾダイマー Download PDFInfo
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- JP2006503068A JP2006503068A JP2004539956A JP2004539956A JP2006503068A JP 2006503068 A JP2006503068 A JP 2006503068A JP 2004539956 A JP2004539956 A JP 2004539956A JP 2004539956 A JP2004539956 A JP 2004539956A JP 2006503068 A JP2006503068 A JP 2006503068A
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- 125000000217 alkyl group Chemical group 0.000 claims description 56
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- 229910052739 hydrogen Inorganic materials 0.000 claims description 38
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- 241001465754 Metazoa Species 0.000 claims description 29
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- 229910052757 nitrogen Inorganic materials 0.000 claims description 17
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- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical group C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 claims description 8
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- ZYSPJZYARGFYMO-UHFFFAOYSA-N 1-[2-[2-[4-amino-2-(2-methoxyethyl)imidazo[4,5-c]quinolin-1-yl]ethoxy]ethyl]-3-[8-[2-[2-[4-amino-2-(2-methoxyethyl)imidazo[4,5-c]quinolin-1-yl]ethoxy]ethylcarbamoylamino]octyl]urea Chemical compound COCCC1=NC2=C(N)N=C3C=CC=CC3=C2N1CCOCCNC(=O)NCCCCCCCCNC(=O)NCCOCCN1C2=C3C=CC=CC3=NC(N)=C2N=C1CCOC ZYSPJZYARGFYMO-UHFFFAOYSA-N 0.000 claims description 2
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/06—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/42—Nitrogen atoms attached in position 4
- C07D215/46—Nitrogen atoms attached in position 4 with hydrocarbon radicals, substituted by nitrogen atoms, attached to said nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41384802P | 2002-09-26 | 2002-09-26 | |
| PCT/US2003/030372 WO2004028539A2 (en) | 2002-09-26 | 2003-09-25 | 1h-imidazo dimers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006503068A true JP2006503068A (ja) | 2006-01-26 |
| JP2006503068A5 JP2006503068A5 (https=) | 2006-11-09 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004539956A Pending JP2006503068A (ja) | 2002-09-26 | 2003-09-25 | １ｈ−イミダゾダイマー |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US6818650B2 (https=) |
| EP (1) | EP1542688A4 (https=) |
| JP (1) | JP2006503068A (https=) |
| AU (1) | AU2003299082A1 (https=) |
| WO (1) | WO2004028539A2 (https=) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010513493A (ja) * | 2006-12-20 | 2010-04-30 | シェーリング コーポレイション | 新規なｊｎｋ阻害剤 |
| JP2012500831A (ja) * | 2008-08-29 | 2012-01-12 | トポターゲット・アクティーゼルスカブ | 新規なウレアおよびチオウレア誘導体 |
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| WO2004028539A3 (en) | 2004-10-28 |
| AU2003299082A1 (en) | 2004-04-19 |
| WO2004028539A2 (en) | 2004-04-08 |
| US7112677B2 (en) | 2006-09-26 |
| US20040132766A1 (en) | 2004-07-08 |
| EP1542688A4 (en) | 2010-06-02 |
| US20050026947A1 (en) | 2005-02-03 |
| US6818650B2 (en) | 2004-11-16 |
| EP1542688A2 (en) | 2005-06-22 |
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