JP2005537282A - セファロタキシンアルカロイドによる血管新生抑制、並びにその誘導体、組成物、および使用方法 - Google Patents
セファロタキシンアルカロイドによる血管新生抑制、並びにその誘導体、組成物、および使用方法 Download PDFInfo
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- JP2005537282A JP2005537282A JP2004523305A JP2004523305A JP2005537282A JP 2005537282 A JP2005537282 A JP 2005537282A JP 2004523305 A JP2004523305 A JP 2004523305A JP 2004523305 A JP2004523305 A JP 2004523305A JP 2005537282 A JP2005537282 A JP 2005537282A
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- cephalotaxin
- host
- vascular disease
- angiogenesis
- homoharringtonine
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| US39765702P | 2002-07-22 | 2002-07-22 | |
| PCT/US2003/022926 WO2004009030A2 (en) | 2002-07-22 | 2003-07-22 | Angiogenesis inhibition by cephalotaxine alkaloids, derivatives, compositions and uses thereof |
Publications (2)
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| JP2005537282A true JP2005537282A (ja) | 2005-12-08 |
| JP2005537282A5 JP2005537282A5 (https=) | 2006-09-07 |
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| JP2004523305A Pending JP2005537282A (ja) | 2002-07-22 | 2003-07-22 | セファロタキシンアルカロイドによる血管新生抑制、並びにその誘導体、組成物、および使用方法 |
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| EP (1) | EP1539179B1 (https=) |
| JP (1) | JP2005537282A (https=) |
| AU (1) | AU2003254120B2 (https=) |
| CA (1) | CA2493544A1 (https=) |
| ES (1) | ES2572145T3 (https=) |
| WO (1) | WO2004009030A2 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102209386B1 (ko) * | 2020-01-09 | 2021-02-01 | 영남대학교 산학협력단 | 호모해링토닌을 유효성분으로 함유하는 대사질환 예방 또는 치료용 약학조성물 |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060211648A1 (en) * | 2000-04-12 | 2006-09-21 | Chemgenex Pharmaceuticals, Inc. | Naphthalimide compositions and uses thereof |
| US7135481B2 (en) * | 2000-04-12 | 2006-11-14 | Chemgenex Pharmaceuticals, Inc. | Naphthalimide compositions and uses thereof |
| US20050170015A1 (en) * | 2000-10-31 | 2005-08-04 | Brown Dennis M. | Antiproliferative colchicine compositions and uses thereof |
| US7901707B2 (en) * | 2004-03-15 | 2011-03-08 | Christine Allen | Biodegradable biocompatible implant and method of manufacturing same |
| JP2008501719A (ja) * | 2004-06-04 | 2008-01-24 | ケムジェネックス・ファーマシューティカルズ・インコーポレイテッド | ナフタルイミドおよびｐａｒｐ−１インヒビターを使用する細胞増殖性疾患の処置方法 |
| JP2008529667A (ja) * | 2005-02-10 | 2008-08-07 | ケムジェネックス・ファーマシューティカルズ・インコーポレイテッド | 医療デバイス |
| AU2008240044B2 (en) * | 2007-04-13 | 2013-09-12 | Teva Pharamceuticals International Gmbh | Oral cephalotaxine dosage forms |
| US8466142B2 (en) | 2008-03-03 | 2013-06-18 | Sloan-Kettering Institute For Cancer Research | Cephalotaxus esters, methods of synthesis, and uses thereof |
| US20120283306A1 (en) * | 2011-04-27 | 2012-11-08 | Georgia Health Sciences University | Mouse model for avm |
| KR102066684B1 (ko) * | 2018-02-19 | 2020-01-15 | 가천대학교 산학협력단 | 개비자나무 추출물 또는 이로부터 분리한 화합물을 유효성분으로 함유하는 자가면역질환의 예방 또는 치료용 조성물 |
| KR102174166B1 (ko) * | 2018-12-13 | 2020-11-04 | 영남대학교 산학협력단 | 호모해링토닌을 유효성분으로 함유하는 세포노화 관련 질환 예방 또는 치료용 조성물 |
| KR102066683B1 (ko) * | 2019-09-16 | 2020-01-15 | 가천대학교 산학협력단 | 개비자나무 추출물 또는 이로부터 분리한 화합물을 유효성분으로 함유하는 자가면역질환의 예방 또는 치료용 조성물 |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000048595A1 (en) * | 1999-02-17 | 2000-08-24 | Bristol-Myers Squibb Co. | A novel anti-angiogenic agent comprising at least one kringle region and an upstream pre-activation domain of plasminogen |
| WO2001034174A2 (en) * | 1999-11-12 | 2001-05-17 | Entremed, Inc. | Methods for administration of therapeutic agents on an antiangiogenic schedule |
| WO2001068098A2 (en) * | 2000-03-15 | 2001-09-20 | Chemgenex Therapeutics, Inc. | Cephalotaxine alkaloid combination compositions and uses thereof |
| WO2002032904A1 (en) * | 2000-10-17 | 2002-04-25 | Oncopharm Corporation | New cephalotaxanes, their method of preparation and their use in treatment of cancers, leukemias, parasites including thus resistant to usual chemotherapeutic agents and as reversal agents |
| WO2002041882A2 (en) * | 2000-11-22 | 2002-05-30 | Novartis Ag | Combination comprising an agent decreasing vegf activity and an agent decreasing egf activity |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US3793454A (en) * | 1971-11-12 | 1974-02-19 | Us Agriculture | Harringtonine and isopharringtonine for treating l1210 or p388 leukemic tumors in mice |
| US4152214A (en) | 1977-10-07 | 1979-05-01 | The United States Of America As Represented By The Secretary Of Agriculture | Production of homodeoxyharringtonine and other cephalotaxine esters by tissue culture |
| JPS5835146A (ja) | 1981-08-28 | 1983-03-01 | Isukura Sangyo Kk | ２−ケト−６−メチル−５−ヘプテン酸エチルエステルの製造方法 |
| US5380747A (en) * | 1992-10-30 | 1995-01-10 | Emory University | Treatment for atherosclerosis and other cardiovascular and inflammatory diseases |
| US5629327A (en) * | 1993-03-01 | 1997-05-13 | Childrens Hospital Medical Center Corp. | Methods and compositions for inhibition of angiogenesis |
| HUT76095A (en) | 1994-04-26 | 1997-06-30 | Childrens Medical Center | Angiostatin and method of use for inhibition of angiogenesis |
| CA2294247C (en) * | 1997-07-01 | 2004-10-26 | Atherogenics, Inc. | Antioxidant enhancement of therapy for hyperproliferative conditions |
| US6025353A (en) * | 1997-11-19 | 2000-02-15 | G.D. Searle & Co. | Method of using cyclooxygenase-2 inhibitors as anti-angiogenic agents |
| WO2000014083A1 (en) * | 1998-09-09 | 2000-03-16 | Inflazyme Pharmaceuticals Ltd. | SUBSTITUTED η-PHENYL-Δ-LACTONES AND ANALOGS THEREOF AND USES RELATED THERETO |
| ATE305312T1 (de) | 2000-04-12 | 2005-10-15 | Chemgenex Pharmaceuticals Inc | Zusammensetzungen welche ein naphthalmid und ein antiproliferatives mittel enthalten |
| US6978497B1 (en) | 2000-06-21 | 2005-12-27 | Shigeo Takizawa | Motivative exercise and lifting aid dual device |
| CN100396286C (zh) * | 2002-12-30 | 2008-06-25 | 北京大学第一医院 | 高三尖杉酯碱和三尖杉酯碱在制备抑制血管生成药物中的应用 |
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2003
- 2003-07-22 WO PCT/US2003/022926 patent/WO2004009030A2/en not_active Ceased
- 2003-07-22 CA CA002493544A patent/CA2493544A1/en not_active Abandoned
- 2003-07-22 AU AU2003254120A patent/AU2003254120B2/en not_active Ceased
- 2003-07-22 ES ES03765931T patent/ES2572145T3/es not_active Expired - Lifetime
- 2003-07-22 JP JP2004523305A patent/JP2005537282A/ja active Pending
- 2003-07-22 EP EP03765931.5A patent/EP1539179B1/en not_active Expired - Lifetime
- 2003-07-22 US US10/625,866 patent/US7642252B2/en not_active Expired - Fee Related
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2009
- 2009-07-07 US US12/498,815 patent/US20090270368A1/en not_active Abandoned
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000048595A1 (en) * | 1999-02-17 | 2000-08-24 | Bristol-Myers Squibb Co. | A novel anti-angiogenic agent comprising at least one kringle region and an upstream pre-activation domain of plasminogen |
| WO2001034174A2 (en) * | 1999-11-12 | 2001-05-17 | Entremed, Inc. | Methods for administration of therapeutic agents on an antiangiogenic schedule |
| WO2001068098A2 (en) * | 2000-03-15 | 2001-09-20 | Chemgenex Therapeutics, Inc. | Cephalotaxine alkaloid combination compositions and uses thereof |
| WO2002032904A1 (en) * | 2000-10-17 | 2002-04-25 | Oncopharm Corporation | New cephalotaxanes, their method of preparation and their use in treatment of cancers, leukemias, parasites including thus resistant to usual chemotherapeutic agents and as reversal agents |
| WO2002041882A2 (en) * | 2000-11-22 | 2002-05-30 | Novartis Ag | Combination comprising an agent decreasing vegf activity and an agent decreasing egf activity |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102209386B1 (ko) * | 2020-01-09 | 2021-02-01 | 영남대학교 산학협력단 | 호모해링토닌을 유효성분으로 함유하는 대사질환 예방 또는 치료용 약학조성물 |
Also Published As
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| US20090270368A1 (en) | 2009-10-29 |
| AU2003254120B2 (en) | 2009-09-10 |
| WO2004009030A3 (en) | 2004-09-10 |
| EP1539179B1 (en) | 2016-03-02 |
| EP1539179A2 (en) | 2005-06-15 |
| ES2572145T3 (es) | 2016-05-30 |
| WO2004009030A2 (en) | 2004-01-29 |
| CA2493544A1 (en) | 2004-01-29 |
| AU2003254120A1 (en) | 2004-02-09 |
| EP1539179A4 (en) | 2007-01-31 |
| US7642252B2 (en) | 2010-01-05 |
| US20040077629A1 (en) | 2004-04-22 |
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