JP2005534333A5 - - Google Patents
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- Publication number
- JP2005534333A5 JP2005534333A5 JP2004527717A JP2004527717A JP2005534333A5 JP 2005534333 A5 JP2005534333 A5 JP 2005534333A5 JP 2004527717 A JP2004527717 A JP 2004527717A JP 2004527717 A JP2004527717 A JP 2004527717A JP 2005534333 A5 JP2005534333 A5 JP 2005534333A5
- Authority
- JP
- Japan
- Prior art keywords
- phage
- promoter
- protein
- stop codon
- regulatory region
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108020004705 Codon Proteins 0.000 claims 5
- 230000001105 regulatory effect Effects 0.000 claims 5
- 101710132601 Capsid protein Proteins 0.000 claims 4
- 101710094648 Coat protein Proteins 0.000 claims 4
- 102100021181 Golgi phosphoprotein 3 Human genes 0.000 claims 4
- 101710125418 Major capsid protein Proteins 0.000 claims 4
- 101710141454 Nucleoprotein Proteins 0.000 claims 4
- 101710083689 Probable capsid protein Proteins 0.000 claims 4
- 108090000623 proteins and genes Proteins 0.000 claims 4
- 108091060545 Nonsense suppressor Proteins 0.000 claims 3
- 108020004707 nucleic acids Proteins 0.000 claims 3
- 102000039446 nucleic acids Human genes 0.000 claims 3
- 150000007523 nucleic acids Chemical class 0.000 claims 3
- 108090000565 Capsid Proteins Proteins 0.000 claims 2
- 102100023321 Ceruloplasmin Human genes 0.000 claims 2
- 241000724791 Filamentous phage Species 0.000 claims 2
- 108010052285 Membrane Proteins Proteins 0.000 claims 2
- 102400000368 Surface protein Human genes 0.000 claims 2
- 230000001939 inductive effect Effects 0.000 claims 2
- 230000002101 lytic effect Effects 0.000 claims 2
- 101100002068 Bacillus subtilis (strain 168) araR gene Proteins 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 102000004190 Enzymes Human genes 0.000 claims 1
- 241000701959 Escherichia virus Lambda Species 0.000 claims 1
- 108700005075 Regulator Genes Proteins 0.000 claims 1
- 101150044616 araC gene Proteins 0.000 claims 1
- PYMYPHUHKUWMLA-WDCZJNDASA-N arabinose Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)C=O PYMYPHUHKUWMLA-WDCZJNDASA-N 0.000 claims 1
- PYMYPHUHKUWMLA-UHFFFAOYSA-N arabinose Natural products OCC(O)C(O)C(O)C=O PYMYPHUHKUWMLA-UHFFFAOYSA-N 0.000 claims 1
- SRBFZHDQGSBBOR-UHFFFAOYSA-N beta-D-Pyranose-Lyxose Natural products OC1COC(O)C(O)C1O SRBFZHDQGSBBOR-UHFFFAOYSA-N 0.000 claims 1
- 210000000234 capsid Anatomy 0.000 claims 1
- WIIZWVCIJKGZOK-RKDXNWHRSA-N chloramphenicol Chemical compound ClC(Cl)C(=O)N[C@H](CO)[C@H](O)C1=CC=C([N+]([O-])=O)C=C1 WIIZWVCIJKGZOK-RKDXNWHRSA-N 0.000 claims 1
- 229960005091 chloramphenicol Drugs 0.000 claims 1
- 238000003776 cleavage reaction Methods 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 230000007017 scission Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/214,654 | 2002-08-07 | ||
| US10/214,654 US7112435B1 (en) | 2002-08-07 | 2002-08-07 | Uncoupling of DNA insert propagation and expression of protein for phage display |
| PCT/US2003/024221 WO2004015142A1 (en) | 2002-08-07 | 2003-08-01 | Uncoupling of dna propagation and expression of protein for phage display |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011210341A Division JP5389882B2 (ja) | 2002-08-07 | 2011-09-27 | Ｄｎａインサート増殖およびファージディスプレイ法のためのタンパク質発現の切り離し |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005534333A JP2005534333A (ja) | 2005-11-17 |
| JP2005534333A5 true JP2005534333A5 (enExample) | 2006-09-14 |
| JP4870351B2 JP4870351B2 (ja) | 2012-02-08 |
Family
ID=31714248
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004527717A Expired - Lifetime JP4870351B2 (ja) | 2002-08-07 | 2003-08-01 | Ｄｎａインサート増殖およびファージディスプレイ法のためのタンパク質発現の切り離し |
| JP2011210341A Expired - Lifetime JP5389882B2 (ja) | 2002-08-07 | 2011-09-27 | Ｄｎａインサート増殖およびファージディスプレイ法のためのタンパク質発現の切り離し |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011210341A Expired - Lifetime JP5389882B2 (ja) | 2002-08-07 | 2011-09-27 | Ｄｎａインサート増殖およびファージディスプレイ法のためのタンパク質発現の切り離し |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7112435B1 (enExample) |
| EP (1) | EP1543160B1 (enExample) |
| JP (2) | JP4870351B2 (enExample) |
| AT (1) | ATE483810T1 (enExample) |
| AU (1) | AU2003257132B2 (enExample) |
| CA (1) | CA2493716A1 (enExample) |
| DE (1) | DE60334466D1 (enExample) |
| DK (1) | DK1543160T3 (enExample) |
| ES (1) | ES2350575T3 (enExample) |
| WO (1) | WO2004015142A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7897381B2 (en) | 2002-08-07 | 2011-03-01 | Ambit Biosciences Corporation | Uncoupling of DNA insert propagation and expression of protein for phage display |
| US7833741B2 (en) * | 2002-08-07 | 2010-11-16 | Ambit Biosciences Corporation | Uncoupling of DNA insert propagation and expression of protein for phage display |
| CA2576195A1 (en) * | 2004-08-05 | 2006-02-16 | Biosite Incorporated | Compositions and methods for phage display of polypeptides |
| GB2428293A (en) * | 2005-07-13 | 2007-01-24 | Domantis Ltd | Phage display libraries |
| MY159327A (en) | 2009-02-27 | 2016-12-25 | Ambit Biosciences Corp | Jak kinase modulating quinazoline derivatives and methods of use thereof |
| MX2012001974A (es) | 2009-08-19 | 2012-04-11 | Ambit Biosciences Corp | Compuestos de biarilo y metodos de uso de los mismos. |
| WO2011056764A1 (en) | 2009-11-05 | 2011-05-12 | Ambit Biosciences Corp. | Isotopically enriched or fluorinated imidazo[2,1-b][1,3]benzothiazoles |
| US9296722B2 (en) | 2010-05-27 | 2016-03-29 | Ambit Biosciences Corporation | Azolyl urea compounds and methods of use thereof |
| WO2011150201A2 (en) | 2010-05-27 | 2011-12-01 | Ambit Biosciences Corporation | Azolyl amide compounds and methods of use thereof |
| EP2611793A1 (en) | 2010-09-01 | 2013-07-10 | Ambit Biosciences Corporation | 2-cycloquinazoline derivatives and methods of use thereof |
| EP2663553B1 (en) | 2010-09-01 | 2015-08-26 | Ambit Biosciences Corporation | Quinoline and isoquinoline derivatives for use as jak modulators |
| WO2012030948A1 (en) | 2010-09-01 | 2012-03-08 | Ambit Biosciences Corporation | Quinazoline compounds and methods of use thereof |
| EP2611448A1 (en) | 2010-09-01 | 2013-07-10 | Ambit Biosciences Corporation | 7-cyclylquinazoline derivatives and methods of use thereof |
| AU2011296078B2 (en) | 2010-09-01 | 2015-06-18 | Ambit Biosciences Corporation | An optically active pyrazolylaminoquinazoline, and pharmaceutical compositions and methods of use thereof |
| EP2611812A1 (en) | 2010-09-01 | 2013-07-10 | Ambit Biosciences Corporation | Thienopyridine and thienopyrimidine compounds and methods of use thereof |
| WO2012030924A1 (en) | 2010-09-01 | 2012-03-08 | Ambit Biosciences Corporation | Azolopyridine and azolopyrimidine compounds and methods of use thereof |
| US20130225614A1 (en) | 2010-09-01 | 2013-08-29 | Ambit Biosciences Corporation | 4-azolylaminoquinazoline derivatives and methods of use thereof |
| AU2012322095B2 (en) | 2011-10-14 | 2017-06-29 | Ambit Biosciences Corporation | Heterocyclic compounds and use thereof as modulators of type III receptor tyrosine kinases |
| US10829484B2 (en) | 2015-07-28 | 2020-11-10 | Plexxikon Inc. | Compounds and methods for kinase modulation, and indications therefor |
| WO2024020328A1 (en) | 2022-07-16 | 2024-01-25 | Eurofins Discoverx Corporation | Binding assays using phage display technology and kits thereof |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5693489A (en) | 1984-03-30 | 1997-12-02 | Associated Universities, Inc. | Cloning and expression of the gene for bacteriophage T7 RNA polymerase |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| US5498538A (en) | 1990-02-15 | 1996-03-12 | The University Of North Carolina At Chapel Hill | Totally synthetic affinity reagents |
| US6172197B1 (en) | 1991-07-10 | 2001-01-09 | Medical Research Council | Methods for producing members of specific binding pairs |
| PT1024191E (pt) | 1991-12-02 | 2008-12-22 | Medical Res Council | Produção de auto-anticorpos a partir de reportórios de segmentos de anticorpo e exibidos em fagos |
| US5770356A (en) * | 1992-09-04 | 1998-06-23 | The Scripps Research Institute | Phagemids coexpressing a surface receptor and a surface heterologous protein |
| ES2156149T3 (es) | 1992-12-04 | 2001-06-16 | Medical Res Council | Proteinas de union multivalente y multiespecificas, su fabricacion y su uso. |
| US5766905A (en) | 1996-06-14 | 1998-06-16 | Associated Universities Inc. | Cytoplasmic bacteriophage display system |
| US20030124555A1 (en) * | 2001-05-21 | 2003-07-03 | Invitrogen Corporation | Compositions and methods for use in isolation of nucleic acid molecules |
| US6541011B2 (en) | 1998-02-11 | 2003-04-01 | Maxygen, Inc. | Antigen library immunization |
| JP2002522029A (ja) * | 1998-07-27 | 2002-07-23 | ジェネンテック・インコーポレーテッド | コートタンパク質の改変によるファージ提示における改良した形質転換効率 |
| CA2383186A1 (en) | 1999-09-03 | 2001-03-15 | Yale University | Method to identify gene function using small molecule probes |
| US7060506B2 (en) | 2000-01-31 | 2006-06-13 | Cyclacel, Ltd. | Compositions and methods for monitoring the modification of modification dependent binding partner polypeptides |
| WO2002085923A2 (en) | 2001-04-19 | 2002-10-31 | The Scripps Research Institute | In vivo incorporation of unnatural amino acids |
| US20030186221A1 (en) | 2002-04-02 | 2003-10-02 | Lockhart David J. | Phage display affinity filter and forward screen |
-
2002
- 2002-08-07 US US10/214,654 patent/US7112435B1/en not_active Expired - Lifetime
-
2003
- 2003-08-01 DE DE60334466T patent/DE60334466D1/de not_active Expired - Lifetime
- 2003-08-01 CA CA002493716A patent/CA2493716A1/en not_active Abandoned
- 2003-08-01 ES ES03784882T patent/ES2350575T3/es not_active Expired - Lifetime
- 2003-08-01 EP EP03784882A patent/EP1543160B1/en not_active Expired - Lifetime
- 2003-08-01 JP JP2004527717A patent/JP4870351B2/ja not_active Expired - Lifetime
- 2003-08-01 AU AU2003257132A patent/AU2003257132B2/en not_active Expired
- 2003-08-01 DK DK03784882.7T patent/DK1543160T3/da active
- 2003-08-01 WO PCT/US2003/024221 patent/WO2004015142A1/en not_active Ceased
- 2003-08-01 AT AT03784882T patent/ATE483810T1/de not_active IP Right Cessation
-
2011
- 2011-09-27 JP JP2011210341A patent/JP5389882B2/ja not_active Expired - Lifetime
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