JP2023512824A5 - - Google Patents

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Publication number
JP2023512824A5
JP2023512824A5 JP2022548118A JP2022548118A JP2023512824A5 JP 2023512824 A5 JP2023512824 A5 JP 2023512824A5 JP 2022548118 A JP2022548118 A JP 2022548118A JP 2022548118 A JP2022548118 A JP 2022548118A JP 2023512824 A5 JP2023512824 A5 JP 2023512824A5
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JP
Japan
Prior art keywords
sequence
seq
protein
acid sequence
promoter
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JP2022548118A
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English (en)
Japanese (ja)
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JP7846626B2 (ja
JP2023512824A (ja
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Priority claimed from PCT/US2021/016720 external-priority patent/WO2021158854A2/en
Publication of JP2023512824A publication Critical patent/JP2023512824A/ja
Publication of JP2023512824A5 publication Critical patent/JP2023512824A5/ja
Application granted granted Critical
Publication of JP7846626B2 publication Critical patent/JP7846626B2/ja
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JP2022548118A 2020-02-07 2021-02-05 大型遺伝子ベクターならびにその送達および使用の方法 Active JP7846626B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202062971555P 2020-02-07 2020-02-07
US62/971,555 2020-02-07
PCT/US2021/016720 WO2021158854A2 (en) 2020-02-07 2021-02-05 Large gene vectors and delivery and uses thereof

Publications (3)

Publication Number Publication Date
JP2023512824A JP2023512824A (ja) 2023-03-29
JP2023512824A5 true JP2023512824A5 (enExample) 2024-02-14
JP7846626B2 JP7846626B2 (ja) 2026-04-15

Family

ID=77200426

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022548118A Active JP7846626B2 (ja) 2020-02-07 2021-02-05 大型遺伝子ベクターならびにその送達および使用の方法

Country Status (8)

Country Link
US (1) US20230090778A1 (enExample)
EP (1) EP4100518A4 (enExample)
JP (1) JP7846626B2 (enExample)
KR (1) KR20220139924A (enExample)
AU (1) AU2021216410A1 (enExample)
BR (1) BR112022015601A2 (enExample)
CA (1) CA3170709A1 (enExample)
WO (1) WO2021158854A2 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020014625A1 (en) 2018-07-13 2020-01-16 Akouos, Inc. Methods of treating non-syndromic sensorineural hearing loss
KR20220157944A (ko) 2020-02-21 2022-11-29 아카우오스, 인크. 인간 대상체에서 비-연령-연관 청각 장애를 치료하기 위한 조성물 및 방법
US20240352086A1 (en) * 2021-08-24 2024-10-24 The Regents Of The University Of California Compositions and methods comprising lipid associated transmembrane domains
CN116836975A (zh) * 2022-03-25 2023-10-03 上海玮美基因科技有限责任公司 一种耳蜗和/或前庭细胞特异性启动子及其应用
CN117106824B (zh) * 2022-05-17 2025-09-02 上海佑音医药生物科技有限公司 一种治疗听力损伤的双载体系统及其应用
WO2024258925A1 (en) 2023-06-12 2024-12-19 Children's Hospital Medical Center Aav-cftr vectors and methods of using same
CN116925239B (zh) * 2023-07-17 2024-10-18 苏州星奥拓维生物技术有限公司 双载体系统表达Otof基因的组合物和方法
CN118308390A (zh) * 2024-04-24 2024-07-09 广州派真生物技术有限公司 一种内含肽联用载体及其应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7405276B2 (en) * 2000-11-01 2008-07-29 Elusys Therapeutics, Inc. Method of producing bispecific molecules by protein trans-splicing
MX2008000985A (es) * 2005-07-21 2008-04-07 Abbott Lab Expresion de gen multiple que incluye construcciones y metodos sorf (cuadro de lectura abierta simple) con poliproteinas, pro-proteinas y proteolisis.
WO2011053699A1 (en) * 2009-10-30 2011-05-05 Abbott Laboratories Sorf constructs and multiple gene expression
KR102096534B1 (ko) * 2011-09-28 2020-04-03 에라 바이오테크, 에스.에이. 분할된 인테인 및 그의 이용
SI3265571T1 (sl) 2015-03-03 2022-10-28 Fondazione Telethon Več vektorski sistem in njegove uporabe
WO2017209280A1 (ja) * 2016-06-03 2017-12-07 国立大学法人鹿児島大学 酵母と断片化cDNAライブラリーを用いたタンパク質の新しい同定法
KR102622411B1 (ko) * 2016-10-14 2024-01-10 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 핵염기 에디터의 aav 전달
WO2018162748A1 (en) * 2017-03-10 2018-09-13 Genethon Treatment of glycogen storage disease iii
CA3065946A1 (en) * 2017-06-05 2018-12-13 Research Institute At Nationwide Children's Hospital Enhanced modified viral capsid proteins
WO2020014625A1 (en) * 2018-07-13 2020-01-16 Akouos, Inc. Methods of treating non-syndromic sensorineural hearing loss
IL282362B2 (en) * 2018-10-15 2025-10-01 Fond Telethon Ets Intein proteins and their uses

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