JP2005533106A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2005533106A5 JP2005533106A5 JP2004521510A JP2004521510A JP2005533106A5 JP 2005533106 A5 JP2005533106 A5 JP 2005533106A5 JP 2004521510 A JP2004521510 A JP 2004521510A JP 2004521510 A JP2004521510 A JP 2004521510A JP 2005533106 A5 JP2005533106 A5 JP 2005533106A5
- Authority
- JP
- Japan
- Prior art keywords
- fatty acid
- film
- film composition
- composition
- forming polymer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 32
- 235000014113 dietary fatty acids Nutrition 0.000 claims 18
- 239000000194 fatty acid Substances 0.000 claims 18
- 229930195729 fatty acid Natural products 0.000 claims 18
- 229920000642 polymer Polymers 0.000 claims 10
- 229940079593 drug Drugs 0.000 claims 8
- 239000003814 drug Substances 0.000 claims 8
- -1 fatty acid ester Chemical class 0.000 claims 7
- 239000008194 pharmaceutical composition Substances 0.000 claims 6
- 238000012377 drug delivery Methods 0.000 claims 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 4
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 claims 3
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 3
- 239000001863 hydroxypropyl cellulose Substances 0.000 claims 3
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 claims 3
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims 2
- 208000010412 Glaucoma Diseases 0.000 claims 2
- 239000004372 Polyvinyl alcohol Substances 0.000 claims 2
- 239000001768 carboxy methyl cellulose Substances 0.000 claims 2
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims 2
- 239000008112 carboxymethyl-cellulose Substances 0.000 claims 2
- 238000001914 filtration Methods 0.000 claims 2
- 230000008018 melting Effects 0.000 claims 2
- 238000002844 melting Methods 0.000 claims 2
- 229920002451 polyvinyl alcohol Polymers 0.000 claims 2
- 238000001356 surgical procedure Methods 0.000 claims 2
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 claims 1
- 239000004354 Hydroxyethyl cellulose Substances 0.000 claims 1
- 229930012538 Paclitaxel Natural products 0.000 claims 1
- 229920002125 Sokalan® Polymers 0.000 claims 1
- 230000001028 anti-proliverative effect Effects 0.000 claims 1
- 239000003963 antioxidant agent Substances 0.000 claims 1
- 230000003078 antioxidant effect Effects 0.000 claims 1
- 239000002738 chelating agent Substances 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 claims 1
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims 1
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims 1
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims 1
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims 1
- 239000007943 implant Substances 0.000 claims 1
- 230000037431 insertion Effects 0.000 claims 1
- 238000003780 insertion Methods 0.000 claims 1
- 229960001592 paclitaxel Drugs 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 239000004584 polyacrylic acid Substances 0.000 claims 1
- 239000004094 surface-active agent Substances 0.000 claims 1
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39584002P | 2002-07-15 | 2002-07-15 | |
| US43272102P | 2002-12-12 | 2002-12-12 | |
| PCT/US2003/020706 WO2004006889A1 (en) | 2002-07-15 | 2003-06-30 | Bioerodible film for ophthalmic drug delivery |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005533106A JP2005533106A (ja) | 2005-11-04 |
| JP2005533106A5 true JP2005533106A5 (enExample) | 2006-07-06 |
| JP4454019B2 JP4454019B2 (ja) | 2010-04-21 |
Family
ID=30118549
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004521510A Expired - Fee Related JP4454019B2 (ja) | 2002-07-15 | 2003-06-30 | 眼薬送達のための生体侵食性フィルム |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US8084054B2 (enExample) |
| EP (1) | EP1521572B1 (enExample) |
| JP (1) | JP4454019B2 (enExample) |
| KR (1) | KR101003514B1 (enExample) |
| CN (1) | CN100500221C (enExample) |
| AT (1) | ATE424187T1 (enExample) |
| AU (1) | AU2003247671B2 (enExample) |
| CA (1) | CA2491312C (enExample) |
| CY (1) | CY1109606T1 (enExample) |
| DE (1) | DE60326455D1 (enExample) |
| DK (1) | DK1521572T3 (enExample) |
| ES (1) | ES2321083T3 (enExample) |
| MX (1) | MXPA05000631A (enExample) |
| PL (1) | PL206379B1 (enExample) |
| PT (1) | PT1521572E (enExample) |
| SI (1) | SI1521572T1 (enExample) |
| WO (1) | WO2004006889A1 (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2006227116A1 (en) * | 2005-03-21 | 2006-09-28 | Santen Pharmaceutical Co., Ltd. | Drug delivery systems for treatment of diseases or conditions |
| US9877973B2 (en) | 2008-05-12 | 2018-01-30 | University Of Utah Research Foundation | Intraocular drug delivery device and associated methods |
| US9095404B2 (en) | 2008-05-12 | 2015-08-04 | University Of Utah Research Foundation | Intraocular drug delivery device and associated methods |
| US10064819B2 (en) | 2008-05-12 | 2018-09-04 | University Of Utah Research Foundation | Intraocular drug delivery device and associated methods |
| WO2009140246A2 (en) | 2008-05-12 | 2009-11-19 | University Of Utah Research Foundation | Intraocular drug delivery device and associated methods |
| US8623395B2 (en) | 2010-01-29 | 2014-01-07 | Forsight Vision4, Inc. | Implantable therapeutic device |
| US8399006B2 (en) | 2009-01-29 | 2013-03-19 | Forsight Vision4, Inc. | Posterior segment drug delivery |
| US20130226111A1 (en) * | 2010-07-29 | 2013-08-29 | Tsukioka Film Pharma Co., Ltd. | Drug support body, and method for producing same |
| EP2600876B1 (en) | 2010-08-05 | 2015-04-29 | Forsight Vision4, Inc. | Combined drug delivery methods and apparatus |
| PL2600930T3 (pl) | 2010-08-05 | 2021-09-06 | Forsight Vision4, Inc. | Urządzenie wstrzykujące do dostarczania leku |
| ES2894940T3 (es) | 2010-08-05 | 2022-02-16 | Forsight Vision4 Inc | Aparato para tratar un ojo |
| CA2818612C (en) | 2010-11-19 | 2020-12-29 | Forsight Vision4, Inc. | Therapeutic agent formulations for implanted devices |
| WO2012153870A1 (ja) * | 2011-05-11 | 2012-11-15 | 帝人株式会社 | 緑内障治療材 |
| US20120302954A1 (en) * | 2011-05-25 | 2012-11-29 | Zhao Jonathon Z | Expandable devices coated with a paclitaxel composition |
| EP2726016B1 (en) | 2011-06-28 | 2023-07-19 | ForSight Vision4, Inc. | An apparatus for collecting a sample of fluid from a reservoir chamber of a therapeutic device for the eye |
| EP2739252A4 (en) | 2011-08-05 | 2015-08-12 | Forsight Vision4 Inc | SMALL MOLECULE ADMINISTRATION USING AN IMPLANTABLE THERAPEUTIC DEVICE |
| SI2755600T1 (sl) | 2011-09-16 | 2021-08-31 | Forsight Vision4, Inc. | Naprava za izmenjavo tekočine |
| WO2013116061A1 (en) | 2012-02-03 | 2013-08-08 | Forsight Vision4, Inc. | Insertion and removal methods and apparatus for therapeutic devices |
| CA2878680C (en) | 2012-07-23 | 2019-09-17 | Crayola, Llc | Dissolvable films and methods of using the same |
| US9968603B2 (en) | 2013-03-14 | 2018-05-15 | Forsight Vision4, Inc. | Systems for sustained intraocular delivery of low solubility compounds from a port delivery system implant |
| CN105246438B (zh) | 2013-03-28 | 2018-01-26 | 弗赛特影像4股份有限公司 | 用于输送治疗物质的眼科植入物 |
| CA2955186C (en) | 2014-07-15 | 2023-08-29 | Forsight Vision4, Inc. | Ocular implant delivery device and method |
| JP2017524034A (ja) | 2014-08-08 | 2017-08-24 | フォーサイト・ビジョン フォー・インコーポレーテッドＦｏｒｓｉｇｈｔ Ｖｉｓｉｏｎ４， Ｉｎｃ． | 受容体型チロシンキナーゼ阻害剤の安定で可溶な製剤およびその調製の方法 |
| WO2016077371A1 (en) | 2014-11-10 | 2016-05-19 | Forsight Vision4, Inc. | Expandable drug delivery devices and method of use |
| KR20180084104A (ko) | 2015-11-20 | 2018-07-24 | 포사이트 비젼4, 인크. | 연장 방출 약물 전달 장치를 위한 다공성 구조물 |
| JP7009384B2 (ja) | 2016-04-05 | 2022-01-25 | フォーサイト・ビジョン フォー・インコーポレーテッド | 移植可能な眼薬送達デバイス |
| KR20200093581A (ko) | 2017-11-21 | 2020-08-05 | 포사이트 비젼4, 인크. | 확장 가능한 포트 전달 시스템을 위한 유체 교환 기기 및 사용 방법 |
| USD1033637S1 (en) | 2022-01-24 | 2024-07-02 | Forsight Vision4, Inc. | Fluid exchange device |
| WO2024059952A1 (en) * | 2022-09-23 | 2024-03-28 | Madd Ophthalmics Ltd. | Mucoadhesive drug delivery systems and methods of use |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6042766B2 (ja) * | 1978-12-09 | 1985-09-25 | 日本化薬株式会社 | 基剤 |
| GB8524421D0 (en) * | 1985-10-03 | 1985-11-06 | Boots Co Plc | Therapeutic agents |
| US4853224A (en) * | 1987-12-22 | 1989-08-01 | Visionex | Biodegradable ocular implants |
| US4880636A (en) * | 1988-05-13 | 1989-11-14 | Franz Robert M | Film coated tablet of ranitidine HCl |
| US4865846A (en) * | 1988-06-03 | 1989-09-12 | Kaufman Herbert E | Drug delivery system |
| US6117425A (en) * | 1990-11-27 | 2000-09-12 | The American National Red Cross | Supplemented and unsupplemented tissue sealants, method of their production and use |
| SK279279B6 (sk) * | 1991-05-13 | 1998-09-09 | The Boots Company Plc | S(-)-nátrium-2-(4-izobutylfenyl)propionát-dihydrát |
| GB9213077D0 (en) * | 1992-06-19 | 1992-08-05 | Erba Carlo Spa | Polymerbound taxol derivatives |
| US5614549A (en) * | 1992-08-21 | 1997-03-25 | Enzon, Inc. | High molecular weight polymer-based prodrugs |
| US5916596A (en) * | 1993-02-22 | 1999-06-29 | Vivorx Pharmaceuticals, Inc. | Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof |
| US6537579B1 (en) | 1993-02-22 | 2003-03-25 | American Bioscience, Inc. | Compositions and methods for administration of pharmacologically active compounds |
| US5362478A (en) * | 1993-03-26 | 1994-11-08 | Vivorx Pharmaceuticals, Inc. | Magnetic resonance imaging with fluorocarbons encapsulated in a cross-linked polymeric shell |
| US5665382A (en) * | 1993-02-22 | 1997-09-09 | Vivorx Pharmaceuticals, Inc. | Methods for the preparation of pharmaceutically active agents for in vivo delivery |
| US5439686A (en) * | 1993-02-22 | 1995-08-08 | Vivorx Pharmaceuticals, Inc. | Methods for in vivo delivery of substantially water insoluble pharmacologically active agents and compositions useful therefor |
| AU673057B2 (en) * | 1993-02-22 | 1996-10-24 | Abraxis Bioscience, Llc | Methods for (in vivo) delivery of biologics and compositionsuseful therefor |
| US6096331A (en) * | 1993-02-22 | 2000-08-01 | Vivorx Pharmaceuticals, Inc. | Methods and compositions useful for administration of chemotherapeutic agents |
| US5886026A (en) * | 1993-07-19 | 1999-03-23 | Angiotech Pharmaceuticals Inc. | Anti-angiogenic compositions and methods of use |
| TW406020B (en) * | 1993-09-29 | 2000-09-21 | Bristol Myers Squibb Co | Stabilized pharmaceutical composition and its method for preparation and stabilizing solvent |
| US5433951A (en) * | 1993-10-13 | 1995-07-18 | Bristol-Myers Squibb Company | Sustained release formulation containing captopril and method |
| US5484608A (en) * | 1994-03-28 | 1996-01-16 | Pharmavene, Inc. | Sustained-release drug delivery system |
| US5626862A (en) * | 1994-08-02 | 1997-05-06 | Massachusetts Institute Of Technology | Controlled local delivery of chemotherapeutic agents for treating solid tumors |
| US6063116A (en) * | 1994-10-26 | 2000-05-16 | Medarex, Inc. | Modulation of cell proliferation and wound healing |
| US5783178A (en) * | 1994-11-18 | 1998-07-21 | Supratek Pharma. Inc. | Polymer linked biological agents |
| US6369116B1 (en) * | 1995-06-02 | 2002-04-09 | Oculex Pharmaceuticals, Inc. | Composition and method for treating glaucoma |
| RU2086218C1 (ru) | 1995-07-26 | 1997-08-10 | Санкт-Петербургская медицинская академия последипломного образования | Способ лечения глаукомы |
| US5736152A (en) * | 1995-10-27 | 1998-04-07 | Atrix Laboratories, Inc. | Non-polymeric sustained release delivery system |
| FR2748209B1 (fr) * | 1996-05-06 | 1998-06-05 | Adir | Composition pharmaceutique a base de matrices lipophiles stabilisees pour la liberation controlee de principes actifs |
| DK0914102T3 (da) | 1996-05-24 | 2006-01-09 | Angiotech Pharm Inc | Præparater og fremgangsmåder til behandling eller forebyggelse af syddomme i legemskanaler |
| US5888493A (en) * | 1996-12-05 | 1999-03-30 | Sawaya; Assad S. | Ophthalmic aqueous gel formulation and related methods |
| EP1023050B1 (en) | 1997-06-27 | 2013-09-25 | Abraxis BioScience, LLC | Novel formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof |
| US6004573A (en) * | 1997-10-03 | 1999-12-21 | Macromed, Inc. | Biodegradable low molecular weight triblock poly(lactide-co-glycolide) polyethylene glycol copolymers having reverse thermal gelation properties |
| US20020164374A1 (en) | 1997-10-29 | 2002-11-07 | John Jackson | Polymeric systems for drug delivery and uses thereof |
| US6146659A (en) * | 1998-07-01 | 2000-11-14 | Neopharm, Inc. | Method of administering liposomal encapsulated taxane |
| US6017948A (en) * | 1998-10-30 | 2000-01-25 | Supergen, Inc. | Water-miscible pharmaceutical compositions |
| AU3287200A (en) * | 1999-03-16 | 2000-10-04 | Merck Patent Gmbh | Composition comprising isoquercetin and ascorbic acid in a sustained release form |
| CA2369740A1 (en) | 1999-04-22 | 2000-11-02 | American Biosciences, Inc. | Long term administration of pharmacologically active agents |
| US6306120B1 (en) * | 1999-06-07 | 2001-10-23 | Ben Gee Tan | Applicator and method for delivery of mitomycin to eye tissues during glaucoma filtering surgery |
| US6375963B1 (en) * | 1999-06-16 | 2002-04-23 | Michael A. Repka | Bioadhesive hot-melt extruded film for topical and mucosal adhesion applications and drug delivery and process for preparation thereof |
| WO2002087563A2 (en) * | 2001-05-01 | 2002-11-07 | Angiotech Pharmaceuticals Inc. | Compositions comprising an anti-microtubule agent and a polypeptide or a polysaccharide and the use thereof for the preparation of a medicament for the treatment of inflammatory conditions |
| US20040058313A1 (en) * | 2002-04-24 | 2004-03-25 | Abreu Marcio Marc | Compositions, targets, methods and devices for the therapy of ocular and periocular disorders |
-
2003
- 2003-06-30 CA CA2491312A patent/CA2491312C/en not_active Expired - Fee Related
- 2003-06-30 DK DK03764333T patent/DK1521572T3/da active
- 2003-06-30 MX MXPA05000631A patent/MXPA05000631A/es active IP Right Grant
- 2003-06-30 EP EP03764333A patent/EP1521572B1/en not_active Expired - Lifetime
- 2003-06-30 KR KR1020057000486A patent/KR101003514B1/ko not_active Expired - Fee Related
- 2003-06-30 WO PCT/US2003/020706 patent/WO2004006889A1/en not_active Ceased
- 2003-06-30 SI SI200331565T patent/SI1521572T1/sl unknown
- 2003-06-30 DE DE60326455T patent/DE60326455D1/de not_active Expired - Lifetime
- 2003-06-30 PL PL374764A patent/PL206379B1/pl not_active IP Right Cessation
- 2003-06-30 JP JP2004521510A patent/JP4454019B2/ja not_active Expired - Fee Related
- 2003-06-30 AU AU2003247671A patent/AU2003247671B2/en not_active Ceased
- 2003-06-30 AT AT03764333T patent/ATE424187T1/de active
- 2003-06-30 US US10/610,090 patent/US8084054B2/en not_active Expired - Fee Related
- 2003-06-30 ES ES03764333T patent/ES2321083T3/es not_active Expired - Lifetime
- 2003-06-30 CN CNB038167921A patent/CN100500221C/zh not_active Expired - Fee Related
- 2003-06-30 PT PT03764333T patent/PT1521572E/pt unknown
-
2009
- 2009-04-28 CY CY20091100469T patent/CY1109606T1/el unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2005533106A5 (enExample) | ||
| CA2491312A1 (en) | Bioerodible film for ophthalmic drug delivery | |
| JP2020169171A5 (enExample) | ||
| JP2008505157A5 (enExample) | ||
| JP2006514052A (ja) | 吸湿性および／または潮解性の薬剤を含む固体分散剤 | |
| JP2010511663A5 (enExample) | ||
| JPWO2002024161A1 (ja) | 直腸下部滞留型坐剤 | |
| JP2010517955A5 (enExample) | ||
| AU2019305565A1 (en) | Certain (2S)- N-[(1A)-1-cyano-2-phenylethyl]-1,4- oxazepane-2-carboxamides for treating inflammatory bowel disease | |
| JP2025116047A5 (ja) | 放射線不透過性ポリマーを含む放射線不透過性液体塞栓組成物 | |
| US20220380761A1 (en) | Oral delivery of oligonucleotides | |
| JP2009533462A (ja) | ブリモニジンおよびチモロールの組成物 | |
| JP2004529145A5 (enExample) | ||
| JP2020510660A5 (enExample) | ||
| JP2003512327A5 (enExample) | ||
| JP2023012533A (ja) | 局所製剤およびその使用 | |
| JP2007512252A (ja) | 緑内障および関連疾患を処置するための新規プロスタミド | |
| JP2013530931A5 (enExample) | ||
| JPH10502083A (ja) | 医療診断用の画像形成のためのｘ線造影剤として有用な２，４，６−トリヨード−５−置換アミノ−イソフタル酸エステル | |
| JP2003509494A5 (enExample) | ||
| JP2005522542A5 (enExample) | ||
| JPH01128924A (ja) | ピペリジノアルカノール誘導体の製剤組成物 | |
| JP6148842B2 (ja) | フタル酸モノマーをベースとする改善された加水分解安定性を有する歯科材料 | |
| JP5836360B2 (ja) | １‐シクロプロピル‐８‐メチル‐７‐［５‐メチル‐６‐（メチルアミノ）‐３‐ピリジニル］‐４‐オキソ‐１，４‐ジヒドロ‐３‐キノリンカルボン酸塩 | |
| US20080051406A1 (en) | Brimonidine and timolol compositions |