JP2005531529A5 - - Google Patents
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- Publication number
- JP2005531529A5 JP2005531529A5 JP2003582128A JP2003582128A JP2005531529A5 JP 2005531529 A5 JP2005531529 A5 JP 2005531529A5 JP 2003582128 A JP2003582128 A JP 2003582128A JP 2003582128 A JP2003582128 A JP 2003582128A JP 2005531529 A5 JP2005531529 A5 JP 2005531529A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutically acceptable
- pharmaceutical composition
- carrier
- compound according
- acceptable salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- 239000000969 carrier Substances 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- 239000003085 diluting agent Substances 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 239000011780 sodium chloride Substances 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 1
- 229910052731 fluorine Chemical group 0.000 claims 1
- 125000001153 fluoro group Chemical group F* 0.000 claims 1
- 125000004435 hydrogen atoms Chemical group [H]* 0.000 claims 1
- 230000001732 thrombotic Effects 0.000 claims 1
- 0 CN(CC1)CCC1N(CC1)CCN1C(C(C1CC1)NC(c(cc1)cc(*)c1OC)=O)=O Chemical compound CN(CC1)CCC1N(CC1)CCN1C(C(C1CC1)NC(c(cc1)cc(*)c1OC)=O)=O 0.000 description 1
Claims (4)
- 式（Ｉ）：
で示される化合物、またはその医薬的に許容し得る塩。 - １−(４−メトキシベンゾイル−Ｄ−シクロプロピルグリシニル)−４−(１−メチル−ピペリジン−４−イル)ピペラジン、またはその医薬的に許容し得る塩。
- 請求項１または２に記載の化合物を医薬的に許容し得る希釈物または担体と一緒に含む、医薬組成物。
- 処置を必要とする被験者における血栓性疾患を処置するのに適応した医薬組成物であって、請求項１または２に記載の化合物を医薬的に許容し得る希釈物または担体と一緒に含む、該医薬組成物。
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36852302P | 2002-04-01 | 2002-04-01 | |
| PCT/US2003/007794 WO2003084929A1 (en) | 2002-04-01 | 2003-03-24 | Certain 1-(d-cyclopropylglycinyl)-4-(piperidin-4-yl)piperazine compounds as inhibitors of the serine protease factor xa |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005531529A JP2005531529A (ja) | 2005-10-20 |
| JP2005531529A5 true JP2005531529A5 (ja) | 2006-05-11 |
Family
ID=28791889
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003582128A Pending JP2005531529A (ja) | 2002-04-01 | 2003-03-24 | セリンプロテアーゼ因子ｘａインヒビターとしての、１−（ｄ−シクロプロピルグリシニル）−４−（ピペリジン−４−イル）ピペラジン化合物 |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US7166606B2 (ja) |
| EP (1) | EP1492767B1 (ja) |
| JP (1) | JP2005531529A (ja) |
| KR (1) | KR20040094892A (ja) |
| CN (1) | CN1288135C (ja) |
| AT (1) | ATE303990T1 (ja) |
| AU (1) | AU2003218147A1 (ja) |
| BR (1) | BR0308870A (ja) |
| CA (1) | CA2478340A1 (ja) |
| CR (1) | CR7497A (ja) |
| DE (1) | DE60301569T2 (ja) |
| DK (1) | DK1492767T3 (ja) |
| EA (1) | EA007300B1 (ja) |
| EC (1) | ECSP045329A (ja) |
| ES (1) | ES2248737T3 (ja) |
| HK (1) | HK1070363A1 (ja) |
| HR (1) | HRP20040900B1 (ja) |
| IL (1) | IL164018A0 (ja) |
| MX (1) | MXPA04009640A (ja) |
| NO (1) | NO20044688L (ja) |
| NZ (1) | NZ535402A (ja) |
| PL (1) | PL373066A1 (ja) |
| UA (1) | UA76849C2 (ja) |
| WO (1) | WO2003084929A1 (ja) |
| ZA (1) | ZA200407418B (ja) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6834308B1 (en) | 2000-02-17 | 2004-12-21 | Audible Magic Corporation | Method and apparatus for identifying media content presented on a media playing device |
| US7363278B2 (en) | 2001-04-05 | 2008-04-22 | Audible Magic Corporation | Copyright detection and protection system and method |
| US8972481B2 (en) | 2001-07-20 | 2015-03-03 | Audible Magic, Inc. | Playlist generation method and apparatus |
| DE102014108210A1 (de) | 2014-06-11 | 2015-12-17 | Dietrich Gulba | Rodentizid |
| US11014920B2 (en) | 2016-11-18 | 2021-05-25 | Merck Sharp & Dohme Corp. | Factor XIIa inhibitors |
| EP4070658A1 (de) | 2021-04-06 | 2022-10-12 | BIORoxx GmbH | Verwendung von blutgerinnungshemmenden verbindungen als rodentizide |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000077027A2 (en) | 1999-06-14 | 2000-12-21 | Tularik Limited | Serine protease inhibitors |
| AU8875798A (en) | 1997-08-29 | 1999-03-22 | Proteus Molecular Design Ltd | Meta-benzamidine derivatives as serin protease inhibitors |
| EP1192132B1 (en) | 1999-06-14 | 2005-09-07 | Eli Lilly And Company | Serine protease inhibitors |
| GB0030303D0 (en) | 2000-12-13 | 2001-01-24 | Lilly Co Eli | Compounds |
| GB0030304D0 (en) * | 2000-12-13 | 2001-01-24 | Lilly Co Eli | Compounds |
| GB0030305D0 (en) | 2000-12-13 | 2001-01-24 | Lilly Co Eli | Compounds |
| GB0030306D0 (en) | 2000-12-13 | 2001-01-24 | Lilly Co Eli | Compounds |
| TWI257389B (en) | 2001-06-12 | 2006-07-01 | Lilly Co Eli | Pharmaceutical compound |
| ES2298386T3 (es) * | 2001-07-26 | 2008-05-16 | Eli Lilly And Company | 1-glicinil-4-(1-metilpiperidin-4-il)piperazinas y -piperidinas como antagonistas del factor xa. |
-
2003
- 2003-03-24 JP JP2003582128A patent/JP2005531529A/ja active Pending
- 2003-03-24 EA EA200401290A patent/EA007300B1/ru not_active IP Right Cessation
- 2003-03-24 BR BR0308870-7A patent/BR0308870A/pt not_active IP Right Cessation
- 2003-03-24 DK DK03714138T patent/DK1492767T3/da active
- 2003-03-24 AU AU2003218147A patent/AU2003218147A1/en not_active Abandoned
- 2003-03-24 KR KR10-2004-7015486A patent/KR20040094892A/ko not_active Application Discontinuation
- 2003-03-24 US US10/486,138 patent/US7166606B2/en not_active Expired - Fee Related
- 2003-03-24 PL PL03373066A patent/PL373066A1/xx unknown
- 2003-03-24 WO PCT/US2003/007794 patent/WO2003084929A1/en active IP Right Grant
- 2003-03-24 IL IL16401803A patent/IL164018A0/xx unknown
- 2003-03-24 MX MXPA04009640A patent/MXPA04009640A/es active IP Right Grant
- 2003-03-24 CN CNB038074141A patent/CN1288135C/zh not_active Expired - Fee Related
- 2003-03-24 CA CA002478340A patent/CA2478340A1/en not_active Abandoned
- 2003-03-24 EP EP03714138A patent/EP1492767B1/en not_active Expired - Lifetime
- 2003-03-24 AT AT03714138T patent/ATE303990T1/de not_active IP Right Cessation
- 2003-03-24 UA UA20041008649A patent/UA76849C2/uk unknown
- 2003-03-24 NZ NZ535402A patent/NZ535402A/en unknown
- 2003-03-24 ES ES03714138T patent/ES2248737T3/es not_active Expired - Lifetime
- 2003-03-24 DE DE60301569T patent/DE60301569T2/de not_active Expired - Fee Related
-
2004
- 2004-09-15 ZA ZA200407418A patent/ZA200407418B/en unknown
- 2004-09-24 CR CR7497A patent/CR7497A/es unknown
- 2004-09-29 EC EC2004005329A patent/ECSP045329A/es unknown
- 2004-09-30 HR HR20040900A patent/HRP20040900B1/xx not_active IP Right Cessation
- 2004-10-29 NO NO20044688A patent/NO20044688L/no not_active Application Discontinuation
-
2005
- 2005-04-11 HK HK05103052A patent/HK1070363A1/xx not_active IP Right Cessation
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