JP2005530822A5 - - Google Patents
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- Publication number
- JP2005530822A5 JP2005530822A5 JP2004512710A JP2004512710A JP2005530822A5 JP 2005530822 A5 JP2005530822 A5 JP 2005530822A5 JP 2004512710 A JP2004512710 A JP 2004512710A JP 2004512710 A JP2004512710 A JP 2004512710A JP 2005530822 A5 JP2005530822 A5 JP 2005530822A5
- Authority
- JP
- Japan
- Prior art keywords
- mass
- suspension
- approximately
- active ingredient
- vehicle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000004480 active ingredient Substances 0.000 claims 10
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims 9
- 239000003981 vehicle Substances 0.000 claims 7
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 6
- 239000007971 pharmaceutical suspension Substances 0.000 claims 6
- 239000002245 particle Substances 0.000 claims 4
- 239000000725 suspension Substances 0.000 claims 4
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims 3
- HEFNNWSXXWATRW-UHFFFAOYSA-N Ibuprofen Chemical compound CC(C)CC1=CC=C(C(C)C(O)=O)C=C1 HEFNNWSXXWATRW-UHFFFAOYSA-N 0.000 claims 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims 3
- 239000007900 aqueous suspension Substances 0.000 claims 3
- 239000003795 chemical substances by application Substances 0.000 claims 3
- 239000013078 crystal Substances 0.000 claims 3
- 235000011187 glycerol Nutrition 0.000 claims 3
- 229960001680 ibuprofen Drugs 0.000 claims 3
- 239000000600 sorbitol Substances 0.000 claims 3
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims 2
- 229920002125 Sokalan® Polymers 0.000 claims 2
- 239000004376 Sucralose Substances 0.000 claims 2
- 238000013019 agitation Methods 0.000 claims 2
- 230000000845 anti-microbial effect Effects 0.000 claims 2
- 229960001631 carbomer Drugs 0.000 claims 2
- 230000005484 gravity Effects 0.000 claims 2
- 230000006641 stabilisation Effects 0.000 claims 2
- 238000011105 stabilization Methods 0.000 claims 2
- BAQAVOSOZGMPRM-QBMZZYIRSA-N sucralose Chemical compound O[C@@H]1[C@@H](O)[C@@H](Cl)[C@@H](CO)O[C@@H]1O[C@@]1(CCl)[C@@H](O)[C@H](O)[C@@H](CCl)O1 BAQAVOSOZGMPRM-QBMZZYIRSA-N 0.000 claims 2
- 235000019408 sucralose Nutrition 0.000 claims 2
- 239000002562 thickening agent Substances 0.000 claims 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 2
- CTKXFMQHOOWWEB-UHFFFAOYSA-N Ethylene oxide/propylene oxide copolymer Chemical compound CCCOC(C)COCCO CTKXFMQHOOWWEB-UHFFFAOYSA-N 0.000 claims 1
- 239000008186 active pharmaceutical agent Substances 0.000 claims 1
- 239000008135 aqueous vehicle Substances 0.000 claims 1
- 235000021028 berry Nutrition 0.000 claims 1
- 230000015556 catabolic process Effects 0.000 claims 1
- 235000008504 concentrate Nutrition 0.000 claims 1
- 239000012141 concentrate Substances 0.000 claims 1
- 230000003750 conditioning effect Effects 0.000 claims 1
- 238000001816 cooling Methods 0.000 claims 1
- 238000006731 degradation reaction Methods 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 239000000796 flavoring agent Substances 0.000 claims 1
- 235000019634 flavors Nutrition 0.000 claims 1
- 239000012530 fluid Substances 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 235000014666 liquid concentrate Nutrition 0.000 claims 1
- 230000000873 masking effect Effects 0.000 claims 1
- 229920001993 poloxamer 188 Polymers 0.000 claims 1
- 229940044519 poloxamer 188 Drugs 0.000 claims 1
- 239000008213 purified water Substances 0.000 claims 1
- 238000003756 stirring Methods 0.000 claims 1
- 239000004094 surface-active agent Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38873402P | 2002-06-17 | 2002-06-17 | |
| PCT/US2003/018922 WO2003105804A1 (en) | 2002-06-17 | 2003-06-17 | Ibuprofen suspension |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005530822A JP2005530822A (ja) | 2005-10-13 |
| JP2005530822A5 true JP2005530822A5 (enExample) | 2006-08-03 |
Family
ID=29736532
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004512710A Pending JP2005530822A (ja) | 2002-06-17 | 2003-06-17 | イブプロフェン懸濁液 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20040258716A1 (enExample) |
| EP (1) | EP1513499B1 (enExample) |
| JP (1) | JP2005530822A (enExample) |
| CN (2) | CN101862292A (enExample) |
| AT (1) | ATE541562T1 (enExample) |
| AU (1) | AU2003238221A1 (enExample) |
| CA (1) | CA2486553C (enExample) |
| ES (1) | ES2379464T3 (enExample) |
| IL (1) | IL165786A0 (enExample) |
| WO (1) | WO2003105804A1 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005076829A2 (en) * | 2004-02-05 | 2005-08-25 | Taro Pharmaceuticals U.S.A., Inc. | Stable loratadine spill resistant formulation |
| US20050266031A1 (en) * | 2004-05-25 | 2005-12-01 | Jay Dickerson | Pharmaceutical suspension composition |
| US8021682B2 (en) * | 2004-08-13 | 2011-09-20 | Gallipot, Inc. | Palatable suspending vehicle for pharmaceutical ingredients |
| US7799331B2 (en) | 2005-08-04 | 2010-09-21 | Taro Pharmaceutical North America, Inc. | Oral suspension of prednisolone acetate |
| US8497258B2 (en) | 2005-11-12 | 2013-07-30 | The Regents Of The University Of California | Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract |
| CA2641450A1 (en) * | 2006-02-06 | 2007-08-16 | Taro Pharmaceuticals North America, Inc. | Spill resistant antibiotic formulations |
| WO2007117605A2 (en) * | 2006-04-06 | 2007-10-18 | Taro Pharmaceuticals North America, Inc. | Novel spill-resistant formulations comprising hydrocolloidal polymers |
| CN101472676B (zh) * | 2006-04-20 | 2013-09-11 | 万罗赛斯公司 | 利用微通道工艺技术处理和/或形成一种非牛顿流体的方法 |
| GB2438287A (en) * | 2006-05-19 | 2007-11-21 | Norbrook Lab Ltd | Stable aqueous suspension |
| FR2922443B1 (fr) * | 2007-10-17 | 2012-11-09 | Georgia Pacific France | Composition cosmetique destinee a impregner un article de nettoyage et/ou de soin de la peau |
| CA2705681C (en) | 2007-11-13 | 2013-06-18 | Meritage Pharma, Inc. | Corticosteroid compositions |
| CA2726726A1 (en) * | 2008-09-10 | 2010-03-18 | Thrubit B.V. | Ibuprofen for topical administration |
| EP2207536A1 (en) | 2008-09-22 | 2010-07-21 | BioChemics, Inc. | Transdermal drug delivery using an osmolyte and vasoactive agent |
| TW201038296A (en) * | 2009-04-27 | 2010-11-01 | Aplicaciones Farmacodinamicas S A Lab De | Ibuprofen lysinate oral suspension |
| EP2440210A4 (en) | 2009-06-12 | 2014-01-29 | Meritage Pharma Inc | METHOD FOR THE TREATMENT OF STOMACH DARM DISEASES |
| KR101683293B1 (ko) * | 2009-06-29 | 2016-12-06 | 라이온 가부시키가이샤 | 경구용 조성물 |
| AR078283A1 (es) * | 2009-09-10 | 2011-10-26 | Bial Portela & Ca Sa | Formulaciones de suspension oral de dibenzazepina carboxamidas |
| US20140080912A1 (en) * | 2012-09-18 | 2014-03-20 | Mcneil-Ppc, Inc. | Suspension Pharmaceutical Formulations Comprising Low Melting Propionic Acid Derivative Particles |
| JP6221644B2 (ja) * | 2012-11-09 | 2017-11-01 | 大正製薬株式会社 | 経口用組成物 |
| WO2015155703A2 (en) | 2014-04-09 | 2015-10-15 | Nanoceutica Laboratories Pvt. Ltd | Composition and method of producing nanoformulation of water insoluble bioactives in aqueous base |
| US20160346300A1 (en) * | 2015-05-29 | 2016-12-01 | Kiel Laboratories, Inc. | Liquid formulations of celecoxib for oral administration |
| CN106397181B (zh) * | 2016-09-08 | 2019-01-01 | 山东理工大学 | 一种通过添加十二烷基硫酸钠自水溶液中制备长针状布洛芬晶体的方法 |
| US20180078516A1 (en) * | 2016-09-19 | 2018-03-22 | Innovazone Labs LLC | Pharmaceutical Composition of Ibuprofen Sodium for Oral Administration |
| US20240000734A1 (en) * | 2020-12-04 | 2024-01-04 | Laboratorios Silanes S.A. De C.V. | Pharmaceutical composition having an analgaesic and an antihistamine for treating respiratory diseases |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2921884A (en) * | 1957-09-30 | 1960-01-19 | Sterling Drug Inc | Pharmaceutical compositions |
| JPS5831210B2 (ja) * | 1973-04-09 | 1983-07-05 | 武田薬品工業株式会社 | アンテイナスイセイケンダクエキノセイゾウホウ |
| US4361580A (en) * | 1980-06-20 | 1982-11-30 | The Upjohn Manufacturing Company | Aluminum ibuprofen pharmaceutical suspensions |
| US4427681A (en) * | 1982-09-16 | 1984-01-24 | Richardson-Vicks, Inc. | Thixotropic compositions easily convertible to pourable liquids |
| DE3532562A1 (de) * | 1985-09-12 | 1987-03-12 | Dolorgiet Gmbh & Co Kg | Transdermal resorbierbare, wasserhaltige zubereitungen von arylpropionsaeurederivaten und verfahren zur herstellung derselben |
| US4684666A (en) * | 1986-08-19 | 1987-08-04 | Haas Pharmaceuticals, Inc. | Stabilized liquid analgesic compositions |
| JPS63218247A (ja) * | 1987-03-06 | 1988-09-12 | Yoshiaki Kawashima | 高機能懸濁液 |
| US4788220A (en) * | 1987-07-08 | 1988-11-29 | American Home Products Corporation (Del.) | Pediatric ibuprofen compositions |
| US4956184A (en) * | 1988-05-06 | 1990-09-11 | Alcide Corporation | Topical treatment of genital herpes lesions |
| US5006360B1 (en) * | 1988-06-27 | 1992-04-28 | Low calorie fat substitute compositions resistant to laxative side effect | |
| US4918103A (en) * | 1988-07-25 | 1990-04-17 | Formulations Development Labs | Liquid oral pharmaceutical compositions of non-steroidal anti-inflammatory drugs |
| US4883660A (en) * | 1988-10-17 | 1989-11-28 | Thames Pharmacal Co., Inc. | Gel bases for pharmaceutical compositions |
| US4975465A (en) * | 1989-03-28 | 1990-12-04 | American Home Products Corporation | Orally administrable ibuprofen compositions |
| NZ234143A (en) * | 1989-06-28 | 1991-10-25 | Mcneil Ppc Inc | Aqueous pharmaceutical suspension formulation for administering substantially insoluble pharmaceutical agents |
| JPH0714872B2 (ja) * | 1990-02-06 | 1995-02-22 | 昭和薬品化工株式会社 | シロップ剤組成物 |
| JP2814138B2 (ja) * | 1990-07-23 | 1998-10-22 | エスエス製薬株式会社 | 懸濁シロップ剤 |
| DE69131200T2 (de) * | 1990-08-02 | 1999-12-09 | Chiron Corp., Emeryville | Herpes simplex virus vp16 impfstoffe |
| US5137183A (en) * | 1990-08-02 | 1992-08-11 | Mikulec Timothy L | Compressible feeding apparatus |
| US5300302A (en) * | 1990-10-04 | 1994-04-05 | Nestec S.A. | Pharmaceutical composition in gel form in a dispensing package |
| US5881926A (en) * | 1993-03-11 | 1999-03-16 | Taro Pharmaceutical Industries, Ltd. | Pharmaceutical compositions in semisolid form and a device for administration thereof |
| IL108366A (en) * | 1993-03-11 | 1999-11-30 | Taro Vit Ind Ltd | Semi-solid pharmaceutical compounds and a device for their use |
| IT1264857B1 (it) * | 1993-06-21 | 1996-10-17 | Zambon Spa | Composizione farmaceutica liquida per uso orale contenente acido 2-(4-isobutilfenil) propionico |
| FR2713931B1 (fr) * | 1993-12-20 | 1996-04-05 | Laurence Paris | Nouvelles compositions pharmaceutiques liquides à base d'ibuprofène et leur procédé de préparation. |
| US5563177A (en) * | 1995-01-30 | 1996-10-08 | American Home Products Corporation | Taste masking guaifenesin containing liquids |
| JPH08333245A (ja) * | 1995-06-07 | 1996-12-17 | Taisho Pharmaceut Co Ltd | イブプロフェン懸濁液剤 |
| CN1220598A (zh) * | 1996-05-02 | 1999-06-23 | 大正制药株式会社 | 水难溶性酸性药物的悬浮液 |
| US5712310A (en) * | 1996-06-14 | 1998-01-27 | Alpharma Uspd, Inc. | Suspension of substantially water-insoluble drugs and methods of their manufacture |
| GB2318511A (en) * | 1996-10-23 | 1998-04-29 | Eurand Int | Process for the preparation of a pharmaceutical composition for rapid suspension in water |
| AU6855198A (en) * | 1997-04-21 | 1998-11-13 | Taisho Pharmaceutical Co., Ltd. | Ibuprofen suspension preparations |
| US5840768A (en) * | 1997-06-04 | 1998-11-24 | Fmc Corporation | MCC: alginate pharmaceutical suspensions |
| US6071523A (en) * | 1998-06-03 | 2000-06-06 | Taro Pharmaceuticals Industries, Ltd. | Spill resistant pharmaceutical compositions in semi-solid form |
| US6190701B1 (en) * | 1999-03-17 | 2001-02-20 | Peter M. Ronai | Composition and method for stable injectable liquids |
| ES2234581T3 (es) * | 1999-04-06 | 2005-07-01 | Ethypharm | Suspension farmaceutica bebible de ibuprofeno. |
| US6557732B2 (en) * | 2000-07-19 | 2003-05-06 | The Procter & Gamble Company | Detergent pack |
| JP2001294528A (ja) * | 2001-06-06 | 2001-10-23 | Kobayashi Kako Kk | アシクロビル懸濁シロップ剤 |
-
2003
- 2003-06-17 ES ES03737116T patent/ES2379464T3/es not_active Expired - Lifetime
- 2003-06-17 CN CN201010140089A patent/CN101862292A/zh active Pending
- 2003-06-17 US US10/462,998 patent/US20040258716A1/en not_active Abandoned
- 2003-06-17 EP EP03737116A patent/EP1513499B1/en not_active Expired - Lifetime
- 2003-06-17 WO PCT/US2003/018922 patent/WO2003105804A1/en not_active Ceased
- 2003-06-17 CN CN038123673A patent/CN1655762B/zh not_active Expired - Fee Related
- 2003-06-17 JP JP2004512710A patent/JP2005530822A/ja active Pending
- 2003-06-17 AU AU2003238221A patent/AU2003238221A1/en not_active Abandoned
- 2003-06-17 CA CA2486553A patent/CA2486553C/en not_active Expired - Fee Related
- 2003-06-17 AT AT03737116T patent/ATE541562T1/de active
-
2004
- 2004-12-15 IL IL16578604A patent/IL165786A0/xx unknown
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