CN1655762B - 布洛芬混悬剂 - Google Patents

布洛芬混悬剂 Download PDF

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Publication number
CN1655762B
CN1655762B CN038123673A CN03812367A CN1655762B CN 1655762 B CN1655762 B CN 1655762B CN 038123673 A CN038123673 A CN 038123673A CN 03812367 A CN03812367 A CN 03812367A CN 1655762 B CN1655762 B CN 1655762B
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CN
China
Prior art keywords
suspension
ibuprofen
viscosity
spill
carbomer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN038123673A
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English (en)
Chinese (zh)
Other versions
CN1655762A (zh
Inventor
高深
丹尼尔·莫罗斯
玛克辛·莫尔登豪尔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Taro Pharmaceuticals USA Inc
Original Assignee
Taro Pharmaceuticals USA Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taro Pharmaceuticals USA Inc filed Critical Taro Pharmaceuticals USA Inc
Publication of CN1655762A publication Critical patent/CN1655762A/zh
Application granted granted Critical
Publication of CN1655762B publication Critical patent/CN1655762B/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN038123673A 2002-06-17 2003-06-17 布洛芬混悬剂 Expired - Fee Related CN1655762B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US38873402P 2002-06-17 2002-06-17
US60/388,734 2002-06-17
PCT/US2003/018922 WO2003105804A1 (en) 2002-06-17 2003-06-17 Ibuprofen suspension

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201010140089A Division CN101862292A (zh) 2002-06-17 2003-06-17 布洛芬混悬剂

Publications (2)

Publication Number Publication Date
CN1655762A CN1655762A (zh) 2005-08-17
CN1655762B true CN1655762B (zh) 2010-05-26

Family

ID=29736532

Family Applications (2)

Application Number Title Priority Date Filing Date
CN038123673A Expired - Fee Related CN1655762B (zh) 2002-06-17 2003-06-17 布洛芬混悬剂
CN201010140089A Pending CN101862292A (zh) 2002-06-17 2003-06-17 布洛芬混悬剂

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201010140089A Pending CN101862292A (zh) 2002-06-17 2003-06-17 布洛芬混悬剂

Country Status (10)

Country Link
US (1) US20040258716A1 (enExample)
EP (1) EP1513499B1 (enExample)
JP (1) JP2005530822A (enExample)
CN (2) CN1655762B (enExample)
AT (1) ATE541562T1 (enExample)
AU (1) AU2003238221A1 (enExample)
CA (1) CA2486553C (enExample)
ES (1) ES2379464T3 (enExample)
IL (1) IL165786A0 (enExample)
WO (1) WO2003105804A1 (enExample)

Families Citing this family (24)

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US7758877B2 (en) * 2004-02-05 2010-07-20 Taro Pharmaceuticals U.S.A., Inc. Stable loratadine spill resistant formulation
US20050266031A1 (en) * 2004-05-25 2005-12-01 Jay Dickerson Pharmaceutical suspension composition
US8021682B2 (en) * 2004-08-13 2011-09-20 Gallipot, Inc. Palatable suspending vehicle for pharmaceutical ingredients
US7799331B2 (en) 2005-08-04 2010-09-21 Taro Pharmaceutical North America, Inc. Oral suspension of prednisolone acetate
US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
CA2641450A1 (en) * 2006-02-06 2007-08-16 Taro Pharmaceuticals North America, Inc. Spill resistant antibiotic formulations
US20100048451A1 (en) * 2006-04-06 2010-02-25 Taro Pharmaceuticals North America, Inc. Novel spill-resistant formulations comprising hydrocolloidal polymers
JP5362552B2 (ja) * 2006-04-20 2013-12-11 ヴェロシス，インク． マイクロチャネルプロセス技術を用いて非ニュートン流体を処理し、および／または形成させるためのプロセス
GB2438287A (en) * 2006-05-19 2007-11-21 Norbrook Lab Ltd Stable aqueous suspension
FR2922443B1 (fr) * 2007-10-17 2012-11-09 Georgia Pacific France Composition cosmetique destinee a impregner un article de nettoyage et/ou de soin de la peau
LT3354276T (lt) 2007-11-13 2020-04-27 Meritage Pharma, Inc. Kompozicijos, skirtos skrandžio ir žarnyno uždegimo gydymui
CA2749941C (en) * 2008-09-10 2018-04-24 Biochemics, Inc. Ibuprofen for topical administration
CA2702604C (en) 2008-09-22 2013-12-03 Biochemics, Inc. Transdermal drug delivery using an osmolyte and vasoactive agent
CN102448499A (zh) * 2009-04-27 2012-05-09 药效学应用实验室股份有限公司 赖氨酸布洛芬口服混悬剂
WO2010144865A2 (en) 2009-06-12 2010-12-16 Meritage Pharma, Inc. Methods for treating gastrointestinal disorders
KR101683293B1 (ko) * 2009-06-29 2016-12-06 라이온 가부시키가이샤 경구용 조성물
KR20120094473A (ko) * 2009-09-10 2012-08-24 바이알 - 포르텔라 앤드 씨에이 에스에이 에슬리카바제핀 아세테이트의 경구용 현탁액 제제
CN104640570B (zh) * 2012-09-18 2017-04-26 麦克内尔-Ppc股份有限公司 包含低熔点丙酸衍生物颗粒的混悬药物制剂
JP6221644B2 (ja) * 2012-11-09 2017-11-01 大正製薬株式会社 経口用組成物
IN2014CH01872A (enExample) 2014-04-09 2015-05-08 Nanoceutica Lab Pvt Ltd
WO2016196085A1 (en) * 2015-05-29 2016-12-08 Kiel Laboratories, Inc. Liquid formulations of celecoxib for oral administration
CN106397181B (zh) * 2016-09-08 2019-01-01 山东理工大学 一种通过添加十二烷基硫酸钠自水溶液中制备长针状布洛芬晶体的方法
US20180078516A1 (en) * 2016-09-19 2018-03-22 Innovazone Labs LLC Pharmaceutical Composition of Ibuprofen Sodium for Oral Administration
MX2022015332A (es) * 2020-12-04 2023-01-11 Laboratorios Silanes S A De C V Composicion farmaceutica de un analgesico y un antihistaminico para el tratamiento de enfermedades respiratorias.

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5300302A (en) * 1990-10-04 1994-04-05 Nestec S.A. Pharmaceutical composition in gel form in a dispensing package
US6102254A (en) * 1993-03-11 2000-08-15 Taro Pharmaceutical Industies Ltd. Pharmaceutical compositions in semisolid form and a device for administration thereof
CN1352548A (zh) * 1999-04-06 2002-06-05 埃迪克埃迪法姆药品实验室 可饮用布洛芬药物悬浮液

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NZ234143A (en) * 1989-06-28 1991-10-25 Mcneil Ppc Inc Aqueous pharmaceutical suspension formulation for administering substantially insoluble pharmaceutical agents
JPH0714872B2 (ja) * 1990-02-06 1995-02-22 昭和薬品化工株式会社 シロップ剤組成物
JP2814138B2 (ja) * 1990-07-23 1998-10-22 エスエス製薬株式会社 懸濁シロップ剤
ATE179614T1 (de) * 1990-08-02 1999-05-15 Chiron Corp Herpes simplex virus vp16 impfstoffe
US5137183A (en) * 1990-08-02 1992-08-11 Mikulec Timothy L Compressible feeding apparatus
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IT1264857B1 (it) * 1993-06-21 1996-10-17 Zambon Spa Composizione farmaceutica liquida per uso orale contenente acido 2-(4-isobutilfenil) propionico
FR2713931B1 (fr) * 1993-12-20 1996-04-05 Laurence Paris Nouvelles compositions pharmaceutiques liquides à base d'ibuprofène et leur procédé de préparation.
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JPH08333245A (ja) * 1995-06-07 1996-12-17 Taisho Pharmaceut Co Ltd イブプロフェン懸濁液剤
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US6071523A (en) * 1998-06-03 2000-06-06 Taro Pharmaceuticals Industries, Ltd. Spill resistant pharmaceutical compositions in semi-solid form
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Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5300302A (en) * 1990-10-04 1994-04-05 Nestec S.A. Pharmaceutical composition in gel form in a dispensing package
US6102254A (en) * 1993-03-11 2000-08-15 Taro Pharmaceutical Industies Ltd. Pharmaceutical compositions in semisolid form and a device for administration thereof
CN1352548A (zh) * 1999-04-06 2002-06-05 埃迪克埃迪法姆药品实验室 可饮用布洛芬药物悬浮液

Also Published As

Publication number Publication date
CA2486553A1 (en) 2003-12-24
EP1513499B1 (en) 2012-01-18
CN1655762A (zh) 2005-08-17
CA2486553C (en) 2012-01-10
WO2003105804A1 (en) 2003-12-24
ATE541562T1 (de) 2012-02-15
IL165786A0 (en) 2006-01-15
US20040258716A1 (en) 2004-12-23
CN101862292A (zh) 2010-10-20
ES2379464T3 (es) 2012-04-26
AU2003238221A1 (en) 2003-12-31
EP1513499A1 (en) 2005-03-16
JP2005530822A (ja) 2005-10-13

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C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20100526

Termination date: 20140617

EXPY Termination of patent right or utility model