JP2005529840A - Ｃｎｓ標的モジュレータを使用するｃｎｓ障害の治療 - Google Patents

Ｃｎｓ標的モジュレータを使用するｃｎｓ障害の治療 Download PDF

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JP2005529840A
JP2005529840A JP2003535718A JP2003535718A JP2005529840A JP 2005529840 A JP2005529840 A JP 2005529840A JP 2003535718 A JP2003535718 A JP 2003535718A JP 2003535718 A JP2003535718 A JP 2003535718A JP 2005529840 A JP2005529840 A JP 2005529840A
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group
compound
cns
therapeutic compound
disorder
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JP2005529840A5 (enExample
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デール エム． エドガー，
デービッド ジー． ハンガウアー，
ハリー ジェファーソン レイトン，
エマニュエル ジェイ． エム． ミグノット，
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ヒプニオン， インコーポレイテッド
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    • C07D211/40—Oxygen atoms
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    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
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    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
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  • Pyridine Compounds (AREA)
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JP2003535718A 2001-10-16 2002-10-16 Ｃｎｓ標的モジュレータを使用するｃｎｓ障害の治療 Pending JP2005529840A (ja)

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US32970101P 2001-10-16 2001-10-16
US38150702P 2002-05-17 2002-05-17
US41424302P 2002-09-27 2002-09-27
PCT/US2002/032970 WO2003032912A2 (en) 2001-10-16 2002-10-16 Treatment of cns disorders using cns target modulators

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JP2005529840A true JP2005529840A (ja) 2005-10-06
JP2005529840A5 JP2005529840A5 (enExample) 2006-01-05

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US (2) US20050009730A1 (enExample)
EP (1) EP1443929A4 (enExample)
JP (1) JP2005529840A (enExample)
AU (1) AU2002347906A2 (enExample)
CA (1) CA2463579A1 (enExample)
WO (1) WO2003032912A2 (enExample)

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JP2004051600A (ja) * 2002-07-24 2004-02-19 Iyaku Bunshi Sekkei Kenkyusho:Kk 造血器型プロスタグランジンｄ２合成酵素阻害剤
JP2005505626A (ja) * 2001-10-16 2005-02-24 エスティーシー ナラ カンパニー リミテッド ピペリジン誘導体、これの製造方法及びこれを含む痴呆治療用薬学的組成物
JP2007516175A (ja) * 2003-06-27 2007-06-21 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 三環式デルタオピオイド調節剤
JP2014224146A (ja) * 2007-12-12 2014-12-04 アムジエン・インコーポレーテツド グリシン輸送体−１阻害薬

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JP2006525299A (ja) * 2003-05-01 2006-11-09 ヴァーナリス リサーチ リミテッド アゼチジンカルボキサミド誘導体及びｃｂ１レセプター媒介障害の治療におけるその使用
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ES2767973T3 (es) * 2008-02-29 2020-06-19 Lantheus Medical Imaging Inc Agentes de contraste para aplicaciones que comprenden formación de imágenes de perfusión
DK2419096T3 (da) 2009-04-15 2020-02-03 Lantheus Medical Imaging Inc Stabilisering af radiofarmaceutiske sammensætninger under anvendelse af ascorbinsyre
CN101838234B (zh) * 2009-06-17 2012-02-08 重庆华邦制药股份有限公司 阿法乙酯衍生物的合成方法
AU2011213568B2 (en) 2010-02-08 2016-05-12 Lantheus Medical Imaging, Inc. Methods and apparatus for synthesizing imaging agents, and intermediates thereof
CN102311381A (zh) * 2010-07-06 2012-01-11 重庆华邦胜凯制药有限公司 阿伐乙酯衍生物的合成方法
CN104540504A (zh) 2012-01-18 2015-04-22 苏州泰飞尔医药有限公司 治疗肺部疾病的高穿透力前药组合物和医药组合物
AU2013203000B9 (en) 2012-08-10 2017-02-02 Lantheus Medical Imaging, Inc. Compositions, methods, and systems for the synthesis and use of imaging agents
CN104447516B (zh) * 2014-12-15 2017-05-31 重庆华邦制药有限公司 一种阿伐斯丁的制备方法
BR112017020307B1 (pt) 2015-03-26 2023-11-07 Jacqueline M. Iversen Usos de uma combinação de naproxeno e fexofenadina
ES2957548T3 (es) 2016-04-15 2024-01-22 Univ Oxford Innovation Ltd Moduladores del receptor de adenosina para el tratamiento de los trastornos del ritmo circadiano
EP3391886A1 (en) 2017-04-19 2018-10-24 Novartis AG The use of a h3r inverse agonist for the treatment of shift work disorder
CN108558860B (zh) * 2018-06-04 2020-12-25 成都伊诺达博医药科技有限公司 一种合成芜地溴铵的方法
CN110903182A (zh) * 2018-09-14 2020-03-24 北京艾德旺科技发展有限公司 简单环保的4-氟-2-甲基苯甲酸的化学合成方法
JP7696354B2 (ja) 2019-10-21 2025-06-20 アライリオン インコーポレイテッド 睡眠障害の治療のためのＨ１および５－ＨＴ２Ａ受容体調節物質としての３－（４－（１１Ｈ－ジベンゾ［ｂ，ｅ］［１，４］アゼピン－６－イル）ピペラジン－１－イル）－プロパン酸誘導体および３－（４－（ジベンゾ［ｂ，ｆ］［１，４］オキサゼピン／チアゼピン／ジアゼピン－１１－イル）ピペラジン－１－イル）－プロパン酸誘導体
WO2022235813A1 (en) * 2021-05-04 2022-11-10 The Texas A&M University System Inhibitors of sars-cov-2

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WO2003032912A8 (en) 2004-08-19
CA2463579A1 (en) 2003-04-24
US7317026B2 (en) 2008-01-08
US20050009730A1 (en) 2005-01-13
US20040142972A1 (en) 2004-07-22
AU2002347906A2 (en) 2003-04-28
EP1443929A4 (en) 2008-02-06

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