JP2005529175A5 - - Google Patents
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- Publication number
- JP2005529175A5 JP2005529175A5 JP2004512769A JP2004512769A JP2005529175A5 JP 2005529175 A5 JP2005529175 A5 JP 2005529175A5 JP 2004512769 A JP2004512769 A JP 2004512769A JP 2004512769 A JP2004512769 A JP 2004512769A JP 2005529175 A5 JP2005529175 A5 JP 2005529175A5
- Authority
- JP
- Japan
- Prior art keywords
- drug
- film
- zajiten
- qacd
- zaditen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003814 drug Substances 0.000 description 2
- 229940079593 drugs Drugs 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- YNQQEYBLVYAWNX-WLHGVMLRSA-N (E)-but-2-enedioic acid;10-(1-methylpiperidin-4-ylidene)-5H-benzo[1,2]cyclohepta[3,4-b]thiophen-4-one Chemical compound OC(=O)\C=C\C(O)=O.C1CN(C)CCC1=C1C2=CC=CC=C2CC(=O)C2=C1C=CS2 YNQQEYBLVYAWNX-WLHGVMLRSA-N 0.000 description 1
- FBPFZTCFMRRESA-KAZBKCHUSA-N D-Mannitol Natural products OC[C@@H](O)[C@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KAZBKCHUSA-N 0.000 description 1
- ZCVMWBYGMWKGHF-UHFFFAOYSA-N Ketotifene Chemical compound C1CN(C)CCC1=C1C2=CC=CC=C2CC(=O)C2=C1C=CS2 ZCVMWBYGMWKGHF-UHFFFAOYSA-N 0.000 description 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 235000010355 mannitol Nutrition 0.000 description 1
- 238000001953 recrystallisation Methods 0.000 description 1
Description
さらに、組成物Ｆ〜Ｋを、組成物ＡおよびＤと同様に製造するが、ただし異なる量のケトチフェン水素フマル酸塩（ザジテン）、すなわちそれぞれ６.７５、１２.５および２０％の割合で添加する。生成した層は、６.７５および１２.５％の薬剤（それぞれＦおよびＩおよびＧおよびＪ）により良好で均等内容の評点を示す。フィルムに４０ｍｇ（２０％）のザジテンを添加すると（Ｈ、Ｋ）、結晶構造の存在がＤ−マンニトールに基いたフィルムで見出される。恐らくはＱＡＣＤ化合物および薬剤間におけるある種の相互作用故に、この再結晶化はＱＡ−ベータ−ＣＤの存在下では起こらない。
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02013074 | 2002-06-13 | ||
| EP02013074.6 | 2002-06-13 | ||
| EP02028554 | 2002-12-20 | ||
| EP02028554.0 | 2002-12-20 | ||
| PCT/EP2003/006192 WO2003105867A1 (en) | 2002-06-13 | 2003-06-12 | Quaternised ammonium cyclodextrin compounds |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010185238A Division JP2011006448A (ja) | 2002-06-13 | 2010-08-20 | 第四級化アンモニウムシクロデキストリン化合物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005529175A JP2005529175A (ja) | 2005-09-29 |
| JP2005529175A5 true JP2005529175A5 (ja) | 2006-07-27 |
| JP4773721B2 JP4773721B2 (ja) | 2011-09-14 |
Family
ID=29737927
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004512769A Expired - Fee Related JP4773721B2 (ja) | 2002-06-13 | 2003-06-12 | 第四級化アンモニウムシクロデキストリン化合物 |
| JP2010185238A Pending JP2011006448A (ja) | 2002-06-13 | 2010-08-20 | 第四級化アンモニウムシクロデキストリン化合物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010185238A Pending JP2011006448A (ja) | 2002-06-13 | 2010-08-20 | 第四級化アンモニウムシクロデキストリン化合物 |
Country Status (15)
| Country | Link |
|---|---|
| US (4) | US20050222085A1 (ja) |
| EP (1) | EP1515729B1 (ja) |
| JP (2) | JP4773721B2 (ja) |
| CN (1) | CN100589809C (ja) |
| AT (1) | ATE386532T1 (ja) |
| AU (1) | AU2003276957A1 (ja) |
| BR (1) | BR0311722A (ja) |
| CA (1) | CA2487332C (ja) |
| CY (1) | CY1108099T1 (ja) |
| DE (1) | DE60319221T2 (ja) |
| DK (1) | DK1515729T3 (ja) |
| ES (1) | ES2301807T3 (ja) |
| PT (1) | PT1515729E (ja) |
| SI (1) | SI1515729T1 (ja) |
| WO (1) | WO2003105867A1 (ja) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100678824B1 (ko) * | 2005-02-04 | 2007-02-05 | 한미약품 주식회사 | 용해성이 증가된 무정형 타크로리무스 고체분산체 및 이를포함하는 약제학적 조성물 |
| EP2004203A4 (en) | 2006-03-28 | 2010-03-31 | Javelin Pharmaceuticals Inc | FORMULATIONS OF DICLOFENAC AND CYCLODEXTRIN BETA WITH LOW DOSAGE |
| WO2008120249A1 (en) * | 2007-03-30 | 2008-10-09 | Sifi S.P.A. | Pharmaceutical formulations based on apolar and polar lipids for ophthalmic use |
| CN101757621B (zh) * | 2008-11-28 | 2012-07-04 | 天津金耀集团有限公司 | 一种眼部抗炎的环糊精包合药物组合物 |
| US9642920B2 (en) * | 2009-06-03 | 2017-05-09 | Case Western Reserve University | Therapeutic agent delivery system and method |
| CN102276761A (zh) * | 2010-06-11 | 2011-12-14 | 南京理工大学 | 单取代铵基正电型-β-环糊精及其制备方法 |
| GB201114459D0 (en) * | 2011-08-22 | 2011-10-05 | Isis Innovation | Anti-bacterial compounds |
| CN103497275B (zh) * | 2013-08-09 | 2015-12-23 | 华北电力大学（保定） | 一种抗菌、抗病毒胍盐星形聚合物及其制备方法和应用 |
| CZ307458B6 (cs) * | 2014-11-25 | 2018-09-12 | Spur A.S. | Vícevrstvý kryt rány s aktivní vrstvou a způsob jeho výroby |
| US20170360040A1 (en) * | 2014-12-02 | 2017-12-21 | B.G. Negev Technologies And Applications Ltd., At Ben-Gurion University | Modified polysaccharides for use as anti-microbial agents |
| CN109487588B (zh) * | 2018-11-19 | 2021-04-20 | 绍兴永通印花有限公司 | 一种印花用涤纶织物处理液及其使用方法 |
| CN114891133B (zh) * | 2019-02-14 | 2023-11-21 | 赛克洛珀股份有限公司 | 带有电荷的环糊精聚合物材料以及其制造和使用方法 |
| CN109836512A (zh) * | 2019-03-04 | 2019-06-04 | 西南石油大学 | 一种新型β-CD双子表面活性剂为稠化剂的清洁压裂液 |
| CN112386710A (zh) * | 2020-12-09 | 2021-02-23 | 星拜(苏州)生物科技有限公司 | 一种利用包埋技术改善紫檀芪水溶性的方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3453257A (en) * | 1967-02-13 | 1969-07-01 | Corn Products Co | Cyclodextrin with cationic properties |
| JPS58210901A (ja) * | 1982-06-01 | 1983-12-08 | Kao Corp | シクロデキストリン誘導体およびその製造方法 |
| IT1229133B (it) * | 1989-03-09 | 1991-07-22 | Farmhispania | Sali ammonici di policiclodestrine per l'impiego come agenti ipocolesterolemizzanti |
| WO1991018022A1 (fr) * | 1990-05-21 | 1991-11-28 | Toppan Printing Co., Ltd. | Derive de cyclodextrine |
| JPH0481401A (ja) * | 1990-07-24 | 1992-03-16 | Toppan Printing Co Ltd | シクロデキストリン誘導体 |
| JPH0665307A (ja) * | 1992-06-17 | 1994-03-08 | Sankyo Co Ltd | シクロデキストリン誘導体 |
| CA2201134A1 (en) * | 1994-10-10 | 1996-04-18 | Alfred Sallmann | Ophthalmic and aural compositions containing diclofenac potassium |
| JP3297969B2 (ja) * | 1994-12-26 | 2002-07-02 | ライオン株式会社 | 点眼剤 |
| US5869079A (en) * | 1995-06-02 | 1999-02-09 | Oculex Pharmaceuticals, Inc. | Formulation for controlled release of drugs by combining hydrophilic and hydrophobic agents |
| TW434023B (en) * | 1995-09-18 | 2001-05-16 | Novartis Ag | Preserved ophthalmic composition |
| AU759280C (en) * | 1998-02-23 | 2004-01-22 | Cyclops, Ehf | High-energy cyclodextrin complexes |
-
2003
- 2003-06-12 BR BR0311722-7A patent/BR0311722A/pt not_active IP Right Cessation
- 2003-06-12 SI SI200331202T patent/SI1515729T1/sl unknown
- 2003-06-12 DE DE60319221T patent/DE60319221T2/de not_active Expired - Lifetime
- 2003-06-12 EP EP03740232A patent/EP1515729B1/en not_active Expired - Lifetime
- 2003-06-12 CA CA2487332A patent/CA2487332C/en not_active Expired - Fee Related
- 2003-06-12 JP JP2004512769A patent/JP4773721B2/ja not_active Expired - Fee Related
- 2003-06-12 WO PCT/EP2003/006192 patent/WO2003105867A1/en active IP Right Grant
- 2003-06-12 CN CN03813614A patent/CN100589809C/zh not_active Expired - Fee Related
- 2003-06-12 PT PT03740232T patent/PT1515729E/pt unknown
- 2003-06-12 AU AU2003276957A patent/AU2003276957A1/en not_active Abandoned
- 2003-06-12 DK DK03740232T patent/DK1515729T3/da active
- 2003-06-12 AT AT03740232T patent/ATE386532T1/de active
- 2003-06-12 US US10/516,247 patent/US20050222085A1/en not_active Abandoned
- 2003-06-12 ES ES03740232T patent/ES2301807T3/es not_active Expired - Lifetime
-
2008
- 2008-05-20 CY CY20081100523T patent/CY1108099T1/el unknown
- 2008-09-26 US US12/238,473 patent/US20090110734A1/en not_active Abandoned
-
2010
- 2010-08-20 JP JP2010185238A patent/JP2011006448A/ja active Pending
-
2011
- 2011-09-16 US US13/234,912 patent/US20120004158A1/en not_active Abandoned
-
2012
- 2012-12-21 US US13/723,257 patent/US20130137657A1/en not_active Abandoned