JP2005528319A5 - - Google Patents

Download PDF

Info

Publication number
JP2005528319A5
JP2005528319A5 JP2003512448A JP2003512448A JP2005528319A5 JP 2005528319 A5 JP2005528319 A5 JP 2005528319A5 JP 2003512448 A JP2003512448 A JP 2003512448A JP 2003512448 A JP2003512448 A JP 2003512448A JP 2005528319 A5 JP2005528319 A5 JP 2005528319A5
Authority
JP
Japan
Prior art keywords
cells
transduced
rrz2
lnl6
marking
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2003512448A
Other languages
English (en)
Japanese (ja)
Other versions
JP2005528319A (ja
JP5179697B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2002/021907 external-priority patent/WO2003006691A1/en
Publication of JP2005528319A publication Critical patent/JP2005528319A/ja
Publication of JP2005528319A5 publication Critical patent/JP2005528319A5/ja
Application granted granted Critical
Publication of JP5179697B2 publication Critical patent/JP5179697B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP2003512448A 2001-07-10 2002-07-10 造血前駆細胞を遺伝的に改変する方法及び改変された細胞の使用 Expired - Fee Related JP5179697B2 (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US30428301P 2001-07-10 2001-07-10
US30412701P 2001-07-10 2001-07-10
US60/304,283 2001-07-10
US60/304,127 2001-07-10
US34348401P 2001-12-21 2001-12-21
US60/343,484 2001-12-21
US38606302P 2002-06-04 2002-06-04
US60/386,063 2002-06-04
PCT/US2002/021907 WO2003006691A1 (en) 2001-07-10 2002-07-10 Methods for genetic modification of hematopoietic progenitor cells and uses of the modified cells

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2009211662A Division JP2010077125A (ja) 2001-07-10 2009-09-14 造血前駆細胞を遺伝的に改変する方法及び改変された細胞の使用

Publications (3)

Publication Number Publication Date
JP2005528319A JP2005528319A (ja) 2005-09-22
JP2005528319A5 true JP2005528319A5 (enExample) 2012-09-27
JP5179697B2 JP5179697B2 (ja) 2013-04-10

Family

ID=27501852

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2003512448A Expired - Fee Related JP5179697B2 (ja) 2001-07-10 2002-07-10 造血前駆細胞を遺伝的に改変する方法及び改変された細胞の使用
JP2009211662A Pending JP2010077125A (ja) 2001-07-10 2009-09-14 造血前駆細胞を遺伝的に改変する方法及び改変された細胞の使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2009211662A Pending JP2010077125A (ja) 2001-07-10 2009-09-14 造血前駆細胞を遺伝的に改変する方法及び改変された細胞の使用

Country Status (15)

Country Link
US (2) US7345025B2 (enExample)
EP (2) EP1414996B1 (enExample)
JP (2) JP5179697B2 (enExample)
KR (1) KR101015913B1 (enExample)
CN (2) CN1553963A (enExample)
AT (1) ATE490322T1 (enExample)
AU (1) AU2002316640C1 (enExample)
BR (1) BR0211079A (enExample)
CA (1) CA2453531A1 (enExample)
DE (1) DE60238486D1 (enExample)
DK (1) DK1414996T3 (enExample)
IL (2) IL159637A0 (enExample)
MX (1) MXPA04000268A (enExample)
NZ (1) NZ530624A (enExample)
WO (1) WO2003006691A1 (enExample)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020058636A1 (en) * 1994-09-21 2002-05-16 Geoffrey P. Symonds Ribozymes targeting the retroviral packaging sequence expression constructs and recombinant retroviruses containing such constructs
CA2190304A1 (en) * 1995-12-15 1997-06-16 Elazar Rabbani Property effecting and/or property exhibiting compositions for therapeutic and diagnostic uses
US6627442B1 (en) * 2000-08-31 2003-09-30 Virxsys Corporation Methods for stable transduction of cells with hiv-derived viral vectors
KR101015913B1 (ko) 2001-07-10 2011-02-23 존슨 앤드 존슨 리서치 피티와이 리미티드 조혈모세포의 유전적 변이 치료 방법 및 변이 세포의 용도
KR20040084885A (ko) * 2001-07-10 2004-10-06 존슨 앤드 존슨 리서치 피티와이 리미티드 형질도입된 조혈 선조 세포의 제조 방법
ES2358187T3 (es) * 2001-07-10 2011-05-06 JOHNSON & JOHNSON RESEARCH PTY LIMITED Procedimientos para la modificación genética de las células progenitoras hematopoyéticas y utilizaciones de las células modificadas.
WO2003022052A1 (en) * 2001-09-13 2003-03-20 California Institute Of Technology Method for expression of small rna molecules within a cell
US7737124B2 (en) 2001-09-13 2010-06-15 California Institute Of Technology Method for expression of small antiviral RNA molecules with reduced cytotoxicity within a cell
DE10212892A1 (de) * 2002-03-20 2003-10-09 Basf Plant Science Gmbh Konstrukte und Verfahren zur Regulation der Genexpression
DE10224750A1 (de) 2002-06-04 2003-12-24 Fresenius Medical Care De Gmbh Vorrichtung zur Behandlung einer medizinischen Flüssigkeit
US20040197316A1 (en) * 2003-02-06 2004-10-07 Tsokos George C. Novel method for the treatment of systemic lupus erythematosus
CA2519975C (en) * 2003-04-08 2013-07-02 Yeda Research And Development Co. Ltd Stem cells having increased sensitivity to a chemoattractant and methods of generating and using same
GB0410130D0 (en) * 2004-05-06 2004-06-09 Molmed Spa Cell preparation
US7935074B2 (en) * 2005-02-28 2011-05-03 Fresenius Medical Care Holdings, Inc. Cassette system for peritoneal dialysis machine
US8197231B2 (en) 2005-07-13 2012-06-12 Purity Solutions Llc Diaphragm pump and related methods
JP4268209B2 (ja) * 2005-07-20 2009-05-27 ソウル ナショナル ユニバーシティ インダストリー ファウンデーション 子宮内膜細胞を用いた造血幹細胞または前駆細胞の培養及び増殖方法
EP2032691A2 (en) * 2006-06-15 2009-03-11 Neostem, Inc Processing procedure for peripheral blood stem cells
JP2011160661A (ja) * 2008-06-02 2011-08-25 Kyowa Hakko Kirin Co Ltd 血球細胞の初期化法
US8112365B2 (en) * 2008-12-19 2012-02-07 Foster Scott C System and method for online employment recruiting and evaluation
US20100210989A1 (en) 2008-12-23 2010-08-19 Janet Lesley Macpherson Processing blood
US8192401B2 (en) 2009-03-20 2012-06-05 Fresenius Medical Care Holdings, Inc. Medical fluid pump systems and related components and methods
CN102438631A (zh) * 2009-04-09 2012-05-02 史坦赛特股份有限公司 抗hiv干细胞及其用途
EP2453946B1 (en) 2009-07-15 2013-02-13 Fresenius Medical Care Holdings, Inc. Medical fluid cassettes and related systems
US8720913B2 (en) 2009-08-11 2014-05-13 Fresenius Medical Care Holdings, Inc. Portable peritoneal dialysis carts and related systems
WO2012074068A1 (ja) * 2010-12-01 2012-06-07 日産化学工業株式会社 ピラゾール化合物による造血幹細胞の製造方法
DE102010053973A1 (de) 2010-12-09 2012-06-14 Fresenius Medical Care Deutschland Gmbh Medizinisches Gerät mit einer Heizung
US9694125B2 (en) 2010-12-20 2017-07-04 Fresenius Medical Care Holdings, Inc. Medical fluid cassettes and related systems and methods
US9624915B2 (en) 2011-03-09 2017-04-18 Fresenius Medical Care Holdings, Inc. Medical fluid delivery sets and related systems and methods
EP2699280B1 (en) 2011-04-21 2015-12-09 Fresenius Medical Care Holdings, Inc. Medical fluid pumping systems and related devices and methods
US9186449B2 (en) 2011-11-01 2015-11-17 Fresenius Medical Care Holdings, Inc. Dialysis machine support assemblies and related systems and methods
US9610392B2 (en) 2012-06-08 2017-04-04 Fresenius Medical Care Holdings, Inc. Medical fluid cassettes and related systems and methods
US9500188B2 (en) 2012-06-11 2016-11-22 Fresenius Medical Care Holdings, Inc. Medical fluid cassettes and related systems and methods
EP4193834B1 (en) * 2012-09-07 2025-05-14 Yale University Methods of using genetically modified mice
KR102402806B1 (ko) * 2012-11-05 2022-05-30 리제너론 파마슈티칼스 인코포레이티드 유전자 변형된 비-인간 동물 및 그것의 사용 방법
CA2893962C (en) 2012-12-06 2021-04-06 Enlivex Therapeutics Ltd Therapeutic apoptotic cell preparations, method for producing same and uses thereof
US9561323B2 (en) 2013-03-14 2017-02-07 Fresenius Medical Care Holdings, Inc. Medical fluid cassette leak detection methods and devices
US10117985B2 (en) 2013-08-21 2018-11-06 Fresenius Medical Care Holdings, Inc. Determining a volume of medical fluid pumped into or out of a medical fluid cassette
CN103471896A (zh) * 2013-09-09 2013-12-25 上海兰卫临床检验有限公司 革兰染色液质控品制备方法
US20200199534A1 (en) * 2017-04-27 2020-06-25 Fred Hutchinson Cancer Research Center Therapeutic formulations containing cd34+ stem cells derived from negative selection
AU2018367546B2 (en) * 2017-11-15 2024-07-18 Weird Science Llc Methods and compositions for non-myeloablative bone marrow reconstitution

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5254678A (en) 1987-12-15 1993-10-19 Gene Shears Pty. Limited Ribozymes
DE3852539T3 (de) 1987-12-15 2005-08-04 Gene Shears Pty. Ltd. Ribozyme.
US5866701A (en) 1988-09-20 1999-02-02 The Board Of Regents For Northern Illinois University Of Dekalb HIV targeted hairpin ribozymes
US4978514A (en) 1989-09-12 1990-12-18 Fuel Tech, Inc. Combined catalytic/non-catalytic process for nitrogen oxides reduction
US5225337A (en) 1989-09-25 1993-07-06 Innovir Laboratories, Inc. Ribozyme compositions and methods for use
US5500357A (en) * 1990-11-02 1996-03-19 Agency Of Industrial Science & Technology, Ministry Of International Trade & Industry RNA transcription system using novel ribozyme
CA2107789A1 (en) 1991-04-05 1992-10-06 Thomas E. Wagner Retrovirus inhibition with antisense nucleic acids complementary to packaging sequences
US5693535A (en) * 1992-05-14 1997-12-02 Ribozyme Pharmaceuticals, Inc. HIV targeted ribozymes
US5525468A (en) * 1992-05-14 1996-06-11 Ribozyme Pharmaceuticals, Inc. Assay for Ribozyme target site
US5911983A (en) 1992-06-26 1999-06-15 University Of Pittsburgh Gene therapy for Gaucher disease using retroviral vectors
ATE312510T1 (de) 1992-06-29 2005-12-15 Gene Shears Pty Ltd Nukleinsäuren und sie verwendende verfahren zur bekämpfung viraler pathogene
CA2154363A1 (en) 1993-01-22 1994-08-04 Bruce A. Sullenger Localization of therapeutic agents
IL108719A0 (en) 1993-02-25 1994-08-26 Ortho Pharma Corp Expression constructs containing hiv inhibitory antisense and other nucleotide sequences, retroviralvectors and recombinant retroviruses containing them
WO1995004818A1 (en) 1993-08-06 1995-02-16 Ribozyme Pharmaceuticals, Inc. Method and reagent for inhibiting human immunodeficiency virus replication
US5624803A (en) * 1993-10-14 1997-04-29 The Regents Of The University Of California In vivo oligonucleotide generator, and methods of testing the binding affinity of triplex forming oligonucleotides derived therefrom
DK1298208T3 (da) 1994-01-05 2006-07-24 Gene Shears Pty Ltd Ribozymer der er målrettet mod en HIV-tat-sekvens
US5712384A (en) * 1994-01-05 1998-01-27 Gene Shears Pty Ltd. Ribozymes targeting retroviral packaging sequence expression constructs and recombinant retroviruses containing such constructs
US20020058636A1 (en) 1994-09-21 2002-05-16 Geoffrey P. Symonds Ribozymes targeting the retroviral packaging sequence expression constructs and recombinant retroviruses containing such constructs
JPH11514209A (ja) 1995-04-20 1999-12-07 カイロン コーポレイション 組換えレトロウイルス調製物による造血幹細胞の高効率エクスビボ形質導入
US5741706A (en) * 1996-06-13 1998-04-21 Immusol, Incorporated Anti-HIV ribozymes
TWI239352B (en) * 1997-07-23 2005-09-11 Takara Bio Inc Gene transfer method with the use of serum-free medium
US6506559B1 (en) * 1997-12-23 2003-01-14 Carnegie Institute Of Washington Genetic inhibition by double-stranded RNA
US6060317A (en) 1998-08-11 2000-05-09 The United States Of America As Represented By The Department Of Health And Human Services Method of transducing mammalian cells, and products related thereto
WO2000034495A2 (en) * 1998-12-04 2000-06-15 City Of Hope A method of genetically modifying very primitive quiescent human hematopoietic stem cells
AU5403100A (en) * 1999-06-08 2000-12-28 Novartis Ag Enforced expression of bcl-xl
EP1317454B1 (en) 2000-09-13 2011-05-25 Vertex Pharmaceuticals Incorporated Caspase inhibitors and uses thereof
EP1354038A2 (en) 2000-12-28 2003-10-22 J & J Research Pty Ltd Double-stranded rna-mediated gene suppression
KR101015913B1 (ko) 2001-07-10 2011-02-23 존슨 앤드 존슨 리서치 피티와이 리미티드 조혈모세포의 유전적 변이 치료 방법 및 변이 세포의 용도
ES2358187T3 (es) 2001-07-10 2011-05-06 JOHNSON & JOHNSON RESEARCH PTY LIMITED Procedimientos para la modificación genética de las células progenitoras hematopoyéticas y utilizaciones de las células modificadas.
KR20040084885A (ko) 2001-07-10 2004-10-06 존슨 앤드 존슨 리서치 피티와이 리미티드 형질도입된 조혈 선조 세포의 제조 방법
KR100646702B1 (ko) * 2001-08-16 2006-11-17 에스케이씨 주식회사 홀 및/또는 그루브로 형성된 화학적 기계적 연마패드

Similar Documents

Publication Publication Date Title
JP2005528319A5 (enExample)
JP2005509846A5 (enExample)
Sueyoshi et al. Slack-adjusted DEA for time series analysis: Performance measurement of Japanese electric power generation industry in 1984–1993
WO2005074467A3 (en) Matrix array nanobiosensor
DE50109149D1 (de) Computertomograph zur Ermittlung des Impulsübertrags-Spektrums in einem Untersuchungsbereich
WO2006082091A3 (en) Low latency massive parallel data processing device
EP1227495A3 (en) Information storage device
AU2001281064A1 (en) Computer based instrumentation and sensing for physical examination training
JPH1062424A5 (enExample)
WO2006083969A3 (en) Blood analysis using a flow imaging cytometer
JP2009533725A5 (enExample)
ATE466930T1 (de) Universelles sammelmedium
DK1487041T3 (da) Elektrolytfilm og fastpolymerbrændselscelle hvori denne anvendes
CY1106056T1 (el) Παραγωγα 2-αμινο-2-αλκυλ-5-επτενοϊκου και επτυνοϊκου οξεος χρησιμα σαν αναστολεις συνθασης νιτρικου οξειδιου
EP1595952A4 (en) METHOD FOR EVALUATING THE ANTITUMOR EFFECT OF A HISTONE DEACETYLASE INHIBITOR
BR0210879A (pt) Método e sistema para prover métricas de performance armazenadas em uma disposição de pelo menos três dimensões, e, meio de armazenamento
CY1110543T1 (el) Προϊον και μεθοδος
WO2004016227A3 (en) Screening methods for cognitive enhancers
WO2004090506A3 (en) Surfaces that selectively bind to moieties
FI20020565A0 (fi) Kennorakenne, laite ja menetelmä
JP2005515282A5 (enExample)
JPH10255030A5 (enExample)
BR9912365A (pt) Disposição deslocada de eletrodos em um transdutor piezoelétrico
WO2006093505A3 (en) Compositions and methods for analyte detection
EP1096369A3 (en) A counter readout control apparatus and control method therefor