JP2005528099A5 - - Google Patents
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- JP2005528099A5 JP2005528099A5 JP2004508275A JP2004508275A JP2005528099A5 JP 2005528099 A5 JP2005528099 A5 JP 2005528099A5 JP 2004508275 A JP2004508275 A JP 2004508275A JP 2004508275 A JP2004508275 A JP 2004508275A JP 2005528099 A5 JP2005528099 A5 JP 2005528099A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- seq
- light chain
- variable domain
- domain sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 210000004408 hybridoma Anatomy 0.000 claims 20
- 108010047041 Complementarity Determining Regions Proteins 0.000 claims 18
- 229920001184 polypeptide Polymers 0.000 claims 11
- 108090000765 processed proteins & peptides Proteins 0.000 claims 11
- 102000004196 processed proteins & peptides Human genes 0.000 claims 11
- 210000004027 cell Anatomy 0.000 claims 10
- 201000010099 disease Diseases 0.000 claims 8
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 8
- 102400000401 Latency-associated peptide Human genes 0.000 claims 4
- 101800001155 Latency-associated peptide Proteins 0.000 claims 4
- 150000001768 cations Chemical class 0.000 claims 4
- 206010028980 Neoplasm Diseases 0.000 claims 3
- 201000011510 cancer Diseases 0.000 claims 3
- 206010016654 Fibrosis Diseases 0.000 claims 2
- 101100274557 Heterodera glycines CLE1 gene Proteins 0.000 claims 2
- 241000124008 Mammalia Species 0.000 claims 2
- 230000001419 dependent effect Effects 0.000 claims 2
- 230000004761 fibrosis Effects 0.000 claims 2
- 230000001404 mediated effect Effects 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 208000024985 Alport syndrome Diseases 0.000 claims 1
- 206010006187 Breast cancer Diseases 0.000 claims 1
- 208000026310 Breast neoplasm Diseases 0.000 claims 1
- 201000009030 Carcinoma Diseases 0.000 claims 1
- 206010008342 Cervix carcinoma Diseases 0.000 claims 1
- 108091026890 Coding region Proteins 0.000 claims 1
- 206010009944 Colon cancer Diseases 0.000 claims 1
- 208000001333 Colorectal Neoplasms Diseases 0.000 claims 1
- 208000000461 Esophageal Neoplasms Diseases 0.000 claims 1
- 208000008839 Kidney Neoplasms Diseases 0.000 claims 1
- 206010023421 Kidney fibrosis Diseases 0.000 claims 1
- 206010023825 Laryngeal cancer Diseases 0.000 claims 1
- 206010058467 Lung neoplasm malignant Diseases 0.000 claims 1
- 208000003445 Mouth Neoplasms Diseases 0.000 claims 1
- 206010030155 Oesophageal carcinoma Diseases 0.000 claims 1
- 206010033128 Ovarian cancer Diseases 0.000 claims 1
- 206010061535 Ovarian neoplasm Diseases 0.000 claims 1
- 208000009565 Pharyngeal Neoplasms Diseases 0.000 claims 1
- 206010034811 Pharyngeal cancer Diseases 0.000 claims 1
- 201000004681 Psoriasis Diseases 0.000 claims 1
- 206010038389 Renal cancer Diseases 0.000 claims 1
- 206010039710 Scleroderma Diseases 0.000 claims 1
- 208000000453 Skin Neoplasms Diseases 0.000 claims 1
- 208000006105 Uterine Cervical Neoplasms Diseases 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 201000010881 cervical cancer Diseases 0.000 claims 1
- 208000019425 cirrhosis of liver Diseases 0.000 claims 1
- 229940127089 cytotoxic agent Drugs 0.000 claims 1
- 239000002254 cytotoxic agent Substances 0.000 claims 1
- 231100000599 cytotoxic agent Toxicity 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 201000004101 esophageal cancer Diseases 0.000 claims 1
- 208000003215 hereditary nephritis Diseases 0.000 claims 1
- 201000010982 kidney cancer Diseases 0.000 claims 1
- 206010023841 laryngeal neoplasm Diseases 0.000 claims 1
- 208000012987 lip and oral cavity carcinoma Diseases 0.000 claims 1
- 201000005202 lung cancer Diseases 0.000 claims 1
- 208000020816 lung neoplasm Diseases 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 208000005069 pulmonary fibrosis Diseases 0.000 claims 1
- 231100000241 scar Toxicity 0.000 claims 1
- 201000000849 skin cancer Diseases 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36499102P | 2002-03-13 | 2002-03-13 | |
| US42628602P | 2002-11-13 | 2002-11-13 | |
| PCT/US2003/008048 WO2003100033A2 (en) | 2002-03-13 | 2003-03-13 | ANTI-αvβ6 ANTIBODIES |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009011451A Division JP2009100763A (ja) | 2002-03-13 | 2009-01-21 | 抗αｖβ６抗体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005528099A JP2005528099A (ja) | 2005-09-22 |
| JP2005528099A5 true JP2005528099A5 (cg-RX-API-DMAC7.html) | 2006-04-27 |
| JP4473117B2 JP4473117B2 (ja) | 2010-06-02 |
Family
ID=29586753
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004508275A Expired - Fee Related JP4473117B2 (ja) | 2002-03-13 | 2003-03-13 | 抗αｖβ６抗体 |
| JP2009011451A Withdrawn JP2009100763A (ja) | 2002-03-13 | 2009-01-21 | 抗αｖβ６抗体 |
| JP2012177349A Withdrawn JP2012228269A (ja) | 2002-03-13 | 2012-08-09 | 抗αｖβ６抗体 |
| JP2012177348A Expired - Lifetime JP5616932B2 (ja) | 2002-03-13 | 2012-08-09 | 抗αｖβ６抗体 |
| JP2014234208A Withdrawn JP2015091807A (ja) | 2002-03-13 | 2014-11-19 | 抗αｖβ６抗体 |
| JP2015048289A Withdrawn JP2015126743A (ja) | 2002-03-13 | 2015-03-11 | 抗αｖβ６抗体 |
Family Applications After (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009011451A Withdrawn JP2009100763A (ja) | 2002-03-13 | 2009-01-21 | 抗αｖβ６抗体 |
| JP2012177349A Withdrawn JP2012228269A (ja) | 2002-03-13 | 2012-08-09 | 抗αｖβ６抗体 |
| JP2012177348A Expired - Lifetime JP5616932B2 (ja) | 2002-03-13 | 2012-08-09 | 抗αｖβ６抗体 |
| JP2014234208A Withdrawn JP2015091807A (ja) | 2002-03-13 | 2014-11-19 | 抗αｖβ６抗体 |
| JP2015048289A Withdrawn JP2015126743A (ja) | 2002-03-13 | 2015-03-11 | 抗αｖβ６抗体 |
Country Status (23)
| Country | Link |
|---|---|
| US (4) | US7465449B2 (cg-RX-API-DMAC7.html) |
| EP (4) | EP2287199B1 (cg-RX-API-DMAC7.html) |
| JP (6) | JP4473117B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR101098109B1 (cg-RX-API-DMAC7.html) |
| CN (4) | CN102659946A (cg-RX-API-DMAC7.html) |
| AR (1) | AR038970A1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2003261071C1 (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0308585B8 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2478833C (cg-RX-API-DMAC7.html) |
| CL (8) | CL2010000789A1 (cg-RX-API-DMAC7.html) |
| EA (1) | EA011853B1 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2389037T3 (cg-RX-API-DMAC7.html) |
| HK (1) | HK1213007A1 (cg-RX-API-DMAC7.html) |
| IL (4) | IL164021A0 (cg-RX-API-DMAC7.html) |
| IS (1) | IS7443A (cg-RX-API-DMAC7.html) |
| ME (1) | ME00804B (cg-RX-API-DMAC7.html) |
| MX (1) | MXPA04008870A (cg-RX-API-DMAC7.html) |
| MY (2) | MY154009A (cg-RX-API-DMAC7.html) |
| NO (1) | NO334834B1 (cg-RX-API-DMAC7.html) |
| NZ (2) | NZ535425A (cg-RX-API-DMAC7.html) |
| PL (1) | PL216223B1 (cg-RX-API-DMAC7.html) |
| RS (1) | RS52488B (cg-RX-API-DMAC7.html) |
| WO (1) | WO2003100033A2 (cg-RX-API-DMAC7.html) |
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