JP2005526064A5 - - Google Patents
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- Publication number
- JP2005526064A5 JP2005526064A5 JP2003574190A JP2003574190A JP2005526064A5 JP 2005526064 A5 JP2005526064 A5 JP 2005526064A5 JP 2003574190 A JP2003574190 A JP 2003574190A JP 2003574190 A JP2003574190 A JP 2003574190A JP 2005526064 A5 JP2005526064 A5 JP 2005526064A5
- Authority
- JP
- Japan
- Prior art keywords
- trifluoromethylphenyl
- cyclopropyl
- hydroxy
- propionylamino
- fluoro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 *C(CC1(CC1)c1c(*)ccc(C(F)(F)F)c1*)(C(N[Al])=O)O Chemical compound *C(CC1(CC1)c1c(*)ccc(C(F)(F)F)c1*)(C(N[Al])=O)O 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36304402P | 2002-03-11 | 2002-03-11 | |
| EP02005530A EP1344776A1 (en) | 2002-03-11 | 2002-03-11 | 5- 2-hydroxy-3-[1-(3-trifluoromethylphenyl)-cyclopropyl]-propionylamino -phtalide and 6- 2-hydroxy-3-[1-(3-trifluoromethylphenyl)-cyclopropyl]-propionylamino -4-methyl-2,3-benzoxazin-1-one derivatives with progesterone receptor modulating activity for use in fertility control, hormone replacement therapy and the treatment of gynecological disorders |
| PCT/EP2003/002441 WO2003075915A1 (en) | 2002-03-11 | 2003-03-10 | 5-}2-hydroxy-3-`1-(3-trifluoromethylphenyl)-cyclopropyl!-propionylamino}- phtalide and related compounds with progesterone receptor modulating activity for use in fertility control and hormone replacement therapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005526064A JP2005526064A (ja) | 2005-09-02 |
| JP2005526064A5 true JP2005526064A5 (https=) | 2006-04-27 |
Family
ID=27806515
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003574190A Pending JP2005526064A (ja) | 2002-03-11 | 2003-03-10 | 受精能制御およびホルモン置換療法における使用のためのプロゲステロン受容体調整活性を有する５−｛２−ヒドロキシ−３−１−（３−トリフルオロメチルフェニル）−シクロプロピル−プロピオニルアミノ｝−フタリドおよび関連化合物 |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US7388006B2 (https=) |
| EP (1) | EP1482925B1 (https=) |
| JP (1) | JP2005526064A (https=) |
| CN (1) | CN1652768A (https=) |
| AR (1) | AR035904A1 (https=) |
| AU (1) | AU2003209720A1 (https=) |
| BR (1) | BR0308394A (https=) |
| CA (1) | CA2478948A1 (https=) |
| CR (1) | CR7490A (https=) |
| DE (1) | DE60311236T2 (https=) |
| DK (1) | DK1482925T3 (https=) |
| ES (1) | ES2280766T3 (https=) |
| HR (1) | HRP20040923A2 (https=) |
| IL (1) | IL164032A0 (https=) |
| MX (1) | MXPA04008881A (https=) |
| NO (1) | NO20044279L (https=) |
| NZ (1) | NZ535427A (https=) |
| PE (1) | PE20040157A1 (https=) |
| PL (1) | PL372490A1 (https=) |
| PT (1) | PT1482925E (https=) |
| RS (1) | RS89504A (https=) |
| RU (1) | RU2314299C2 (https=) |
| TW (1) | TW200307674A (https=) |
| UA (1) | UA78027C2 (https=) |
| UY (1) | UY27715A1 (https=) |
| WO (1) | WO2003075915A1 (https=) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102004062182B4 (de) * | 2004-12-20 | 2007-06-06 | Bayer Schering Pharma Ag | Transdermales Pflaster mit Progesteron A-Spezifische Liganden (PRASL) als Wirkstoff |
| US20070015689A1 (en) * | 2005-06-23 | 2007-01-18 | Alza Corporation | Complexation of metal ions with polypeptides |
| US7408060B2 (en) | 2005-06-24 | 2008-08-05 | Schering Ag | Nonsteroidal progesterone receptor modulators |
| DE102005030294A1 (de) * | 2005-06-24 | 2007-01-04 | Schering Ag | Nichtsteroidale Progesteronrezeptor-Modulatoren |
| US7261742B2 (en) | 2005-10-13 | 2007-08-28 | S.C. Johnson & Son, Inc. | Method of deodorizing a textile |
| AU2006324090B2 (en) * | 2005-12-09 | 2012-05-31 | F. Hoffmann-La Roche Ag | Propionamide compounds as antiinflammatory agents |
| BRPI0619518A2 (pt) * | 2005-12-09 | 2011-10-11 | Hoffmann La Roche | moduladores do receptor de glicocorticoide, composição farmacêutica que os compreende e usos dos mesmos |
| DE102006061913A1 (de) * | 2006-12-21 | 2008-06-26 | Bayer Schering Pharma Aktiengesellschaft | Nichtsteroidale Progesteronrezeptor-Modulatoren |
| UY30805A1 (es) * | 2006-12-21 | 2008-07-31 | Bayer Schering Pharma Ag | Moduladores no esteroides de receptores de progesterona |
| CN101289408B (zh) * | 2007-04-18 | 2013-02-27 | 中国科学院上海药物研究所 | 非甾体类孕激素受体调节剂及其制备方法、药物组合物和用途 |
| DE102007032800A1 (de) | 2007-07-10 | 2009-01-15 | Bayer Schering Pharma Aktiengesellschaft | Nichtsteroidale Progesteronrezeptor-Modulatoren |
| DE102007058747A1 (de) * | 2007-12-05 | 2009-06-10 | Bayer Schering Pharma Aktiengesellschaft | Nichtsteroidale Progesteronrezeptor-Modulatoren |
| BRPI0819571A2 (pt) * | 2007-12-20 | 2019-09-24 | Teva Womenss Health Inc | "método para contracepção de emergência, pacote farmacêutico para contracepção de emergência e composição farmacêutica" |
| BR112014012444B1 (pt) | 2011-11-23 | 2021-12-14 | Therapeuticsmd, Inc | Composição farmacêutica compreendendo estradiol solubilizado, progesterona e um agente de solubilização, bem como usos desta para tratar um sintoma relacionado à menopausa em uma mulher |
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
| US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
| US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
| JP6564369B2 (ja) | 2013-12-09 | 2019-08-21 | デュレクト コーポレイション | 薬学的活性剤複合体、ポリマー複合体、ならびにこれらを伴う組成物及び方法 |
| RU2016143081A (ru) | 2014-05-22 | 2018-06-26 | Терапьютиксмд, Инк. | Натуральные комбинированные гормонозаместительные составы и терапии |
| US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
| US10286077B2 (en) | 2016-04-01 | 2019-05-14 | Therapeuticsmd, Inc. | Steroid hormone compositions in medium chain oils |
| US9931349B2 (en) | 2016-04-01 | 2018-04-03 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical composition |
| WO2018206521A1 (en) * | 2017-05-10 | 2018-11-15 | Ventana Medical Systems, Inc. | STABILIZED TWO-PART HEMATOXYLIN SOLUTION UTILIZING pH ADJUSTMENT |
| US11633405B2 (en) | 2020-02-07 | 2023-04-25 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical formulations |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8617653D0 (en) * | 1986-07-18 | 1986-08-28 | Ici Plc | Amide derivatives |
| US6245804B1 (en) * | 1997-05-30 | 2001-06-12 | Schering Aktiengesellschaft | Nonsteroidal gestagens |
| DE19723722A1 (de) * | 1997-05-30 | 1998-12-10 | Schering Ag | Nichtsteroidale Gestagene |
| NO312255B1 (no) * | 2000-06-28 | 2002-04-15 | Pgs Reservoir Consultants As | Verktöy for gjennomhulling av et langsgående veggparti av et fôringsrör |
| DE10038639A1 (de) * | 2000-07-28 | 2002-02-21 | Schering Ag | Nichtsteroidale Entzündungshemmer |
| WO2002054064A2 (en) * | 2000-12-28 | 2002-07-11 | Schering Ag | Method for screening for progesterone receptor isoform-specific ligands |
-
2003
- 2003-03-10 JP JP2003574190A patent/JP2005526064A/ja active Pending
- 2003-03-10 IL IL16403203A patent/IL164032A0/xx unknown
- 2003-03-10 CA CA002478948A patent/CA2478948A1/en not_active Abandoned
- 2003-03-10 PT PT03743862T patent/PT1482925E/pt unknown
- 2003-03-10 HR HRP20040923 patent/HRP20040923A2/hr not_active Application Discontinuation
- 2003-03-10 DK DK03743862T patent/DK1482925T3/da active
- 2003-03-10 WO PCT/EP2003/002441 patent/WO2003075915A1/en not_active Ceased
- 2003-03-10 ES ES03743862T patent/ES2280766T3/es not_active Expired - Lifetime
- 2003-03-10 DE DE60311236T patent/DE60311236T2/de not_active Expired - Fee Related
- 2003-03-10 BR BR0308394-2A patent/BR0308394A/pt not_active IP Right Cessation
- 2003-03-10 MX MXPA04008881A patent/MXPA04008881A/es not_active Application Discontinuation
- 2003-03-10 AU AU2003209720A patent/AU2003209720A1/en not_active Abandoned
- 2003-03-10 NZ NZ535427A patent/NZ535427A/en unknown
- 2003-03-10 CN CNA038106590A patent/CN1652768A/zh active Pending
- 2003-03-10 RU RU2004130430/04A patent/RU2314299C2/ru not_active IP Right Cessation
- 2003-03-10 EP EP03743862A patent/EP1482925B1/en not_active Expired - Lifetime
- 2003-03-10 RS YU89504A patent/RS89504A/sr unknown
- 2003-03-10 PL PL03372490A patent/PL372490A1/xx not_active Application Discontinuation
- 2003-03-11 PE PE2003000244A patent/PE20040157A1/es not_active Application Discontinuation
- 2003-03-11 TW TW092105213A patent/TW200307674A/zh unknown
- 2003-03-11 UY UY27715A patent/UY27715A1/es not_active Application Discontinuation
- 2003-03-11 AR ARP030100820A patent/AR035904A1/es active IP Right Grant
- 2003-03-11 US US10/384,775 patent/US7388006B2/en not_active Expired - Fee Related
- 2003-10-03 UA UA20041008153A patent/UA78027C2/uk unknown
-
2004
- 2004-09-21 CR CR7490A patent/CR7490A/es not_active Application Discontinuation
- 2004-10-08 NO NO20044279A patent/NO20044279L/no not_active Application Discontinuation
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