JP2005521526A - 薬剤を皮内に供給するデバイス - Google Patents
薬剤を皮内に供給するデバイス Download PDFInfo
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- JP2005521526A JP2005521526A JP2003581834A JP2003581834A JP2005521526A JP 2005521526 A JP2005521526 A JP 2005521526A JP 2003581834 A JP2003581834 A JP 2003581834A JP 2003581834 A JP2003581834 A JP 2003581834A JP 2005521526 A JP2005521526 A JP 2005521526A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M2005/14268—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body with a reusable and a disposable component
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M2005/14506—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons mechanically driven, e.g. spring or clockwork
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0023—Drug applicators using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/003—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Dermatology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Vascular Medicine (AREA)
- Medical Informatics (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Abstract
Description
Claims (18)
- ハウジングと、
該ハウジングに取り外し可能に受容され、患者に供給される物質を収納するのに適合した内部リザーバを画成するカートリッジと、
前記患者の皮膚を貫くのに十分な長さを有し、前記リザーバと流体連通するよう配置されて前記患者に物質を供給するための少なくとも1つの皮膚貫入部材と、
を具えた皮内供給デバイス。 - 前記皮膚貫入部材が前記カートリッジに結合され、前記皮膚貫入部材は、ベースと、外側端と、前記ベースおよび前記外側端の間で延在する通路と、を有し、前記ベースが前記リザーバと流体連通するのに適合している、請求項1の供給デバイス。
- 前記ハウジングは、上縁と、底縁と、前記カートリッジに受容するよう寸法づけられた内部チャンバと、を有し、前記ハウジングがさらに、前記デバイスを前記患者の皮膚に結合させるための結合部材を含んでいる請求項1の供給デバイス。
- 前記ハウジングの前記結合部材が前記患者の皮膚に結合するストラップである請求項3の供給デバイス。
- 前記カートリッジに供給圧力を加えるよう操作可能で、前記リザーバから前記皮膚貫入部材を通って物質が患者に供給されるようにするための供給部材をさらに具えた請求項1の供給デバイス。
- 前記カートリッジが前記供給部材によって押し潰し可能である請求項5の供給デバイス。
- 前記供給部材が前記ハウジングに軸支されて開放位置と閉塞位置との間で回動可能であり、前記閉塞位置にあるときに前記供給部材が前記カートリッジに接触して前記カートリッジに前記供給圧力を加えるようにした請求項6の供給デバイス。
- 前記供給部材は、前記カートリッジと接触して前記カートリッジに前記供給圧力を加えるばね部材を具えている請求項7の供給デバイス。
- 前記供給部材は前記ハウジングに軸支されたカバーをさらに具え、前記ばね部材は前記カバーに固定された第1端と第2の自由端とを有している請求項8の供給デバイス。
- 前記ばねの前記自由端は、前記ばねが弛緩位置にあるときに前記カバーを通して視認可能で、前記ばね部材が応力を生じるときには前記カバーを通して視認できないインジケータを含んでいる請求項9の供給デバイス。
- 前記カバーは、前記ばねが弛緩位置にあるときに前記カバーを通して前記インジケータを視認するための窓を含んでいる請求項10の供給デバイス。
- 前記カートリッジから前記物質が供給されたことを示すためのインジケータをさらに具えた請求項1の供給デバイス。
- 前記カートリッジのための供給部材を形成するカバー部材をさらに具え、該カバー部材が前記ハウジングに回動可能に接続されて開放位置および閉塞位置間で回動可能であり、前記カバー部材は、前記閉塞位置にあるときに前記ハウジングに前記カートリッジを受容して前記カートリッジに供給圧力を加えるようにした請求項1の供給デバイス。
- 前記リザーバの壁を貫通して前記リザーバから前記皮膚貫入部材への流体の流れを許容する貫通部材をさらに具えた請求項13の供給デバイス。
- 前記カバー部材は、前記閉塞位置にあるときに、前記貫通部材を作動させて前記リザーバの前記壁を貫通するよう向きが定められたカム面を含んでいる請求項14の供給デバイス。
- 前記カートリッジは、前記貫通部材によって貫通が行われたときに前記リザーバの壁と前記皮膚貫入部材との間で流体の通路を形成する請求項13の供給デバイス。
- 前記皮膚貫入部材が約50ミクロンないし約5000ミクロンの長さを有している請求項1の供給デバイス。
- 前記皮膚貫入部材は配列された複数の皮膚貫入部材の1つであり、その各々が前記リザーバと流体連通するよう適合している請求項1の供給デバイス。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/112,757 US6780171B2 (en) | 2002-04-02 | 2002-04-02 | Intradermal delivery device |
PCT/US2003/009708 WO2003084597A1 (en) | 2002-04-02 | 2003-03-31 | Device for intradermal medicament delivery |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2005521526A true JP2005521526A (ja) | 2005-07-21 |
JP4384917B2 JP4384917B2 (ja) | 2009-12-16 |
Family
ID=28453419
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2003581834A Expired - Lifetime JP4384917B2 (ja) | 2002-04-02 | 2003-03-31 | 薬剤を皮内に供給するデバイス |
Country Status (9)
Country | Link |
---|---|
US (3) | US6780171B2 (ja) |
EP (2) | EP1700615B1 (ja) |
JP (1) | JP4384917B2 (ja) |
AT (2) | ATE451946T1 (ja) |
AU (1) | AU2003220592B2 (ja) |
CA (1) | CA2480477A1 (ja) |
DE (2) | DE60330605D1 (ja) |
ES (2) | ES2338352T3 (ja) |
WO (1) | WO2003084597A1 (ja) |
Cited By (12)
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JP2006525046A (ja) * | 2003-05-08 | 2006-11-09 | ノボ・ノルデイスク・エー/エス | 取り外し可能な針挿入作動部を有する皮膚に取り付け可能な注入装置 |
JP2016523644A (ja) * | 2013-06-25 | 2016-08-12 | エルテーエス ローマン テラピー−ジステーメ アーゲー | 経皮吸収治療システム、および位置決め用補助器具、および貫入用補助器具を備えるデバイス |
JP2019536572A (ja) * | 2016-12-05 | 2019-12-19 | クロノ セラピューティクス インコーポレイテッドChrono Therapeutics Inc. | 薬剤経皮送達装置及び方法 |
JP2020501668A (ja) * | 2016-12-16 | 2020-01-23 | ソレント・セラピューティクス・インコーポレイテッド | 流体送達装置用の取付バンド及びその使用方法 |
CN111163833A (zh) * | 2017-08-09 | 2020-05-15 | Lts勒曼治疗系统股份公司 | 具有框架、有效成分垫和盖的适配器系统 |
JP2020174855A (ja) * | 2019-04-17 | 2020-10-29 | 富士フイルム株式会社 | 収容容器、マイクロニードルユニット、収容容器群、及びマイクロニードルユニットの製造方法 |
US11285306B2 (en) | 2017-01-06 | 2022-03-29 | Morningside Venture Investments Limited | Transdermal drug delivery devices and methods |
US11400266B2 (en) | 2015-01-28 | 2022-08-02 | Morningside Venture Investments Limited | Drug delivery methods and systems |
US11471424B2 (en) | 2004-09-13 | 2022-10-18 | Morningside Venture Investments Limited | Biosynchronous transdermal drug delivery |
WO2023276090A1 (ja) * | 2021-06-30 | 2023-01-05 | シンクランド株式会社 | 経皮投与装置及び経皮投与システム |
US11596779B2 (en) | 2018-05-29 | 2023-03-07 | Morningside Venture Investments Limited | Drug delivery methods and systems |
US12017029B2 (en) | 2023-03-03 | 2024-06-25 | Morningside Venture Investments Limited | Drug delivery methods and systems |
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JP2016523644A (ja) * | 2013-06-25 | 2016-08-12 | エルテーエス ローマン テラピー−ジステーメ アーゲー | 経皮吸収治療システム、および位置決め用補助器具、および貫入用補助器具を備えるデバイス |
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JP2020530795A (ja) * | 2017-08-09 | 2020-10-29 | エルテーエス ローマン テラピー−ジステーメ アーゲー | フレーム、有効成分パッド、およびカバーを含むアダプタシステム |
US11596779B2 (en) | 2018-05-29 | 2023-03-07 | Morningside Venture Investments Limited | Drug delivery methods and systems |
JP7074714B2 (ja) | 2019-04-17 | 2022-05-24 | 富士フイルム株式会社 | 収容容器、マイクロニードルユニット、収容容器群、及びマイクロニードルユニットの製造方法 |
JP2020174855A (ja) * | 2019-04-17 | 2020-10-29 | 富士フイルム株式会社 | 収容容器、マイクロニードルユニット、収容容器群、及びマイクロニードルユニットの製造方法 |
WO2023276090A1 (ja) * | 2021-06-30 | 2023-01-05 | シンクランド株式会社 | 経皮投与装置及び経皮投与システム |
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Also Published As
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US7156838B2 (en) | 2007-01-02 |
DE60305901D1 (de) | 2006-07-20 |
DE60305901T2 (de) | 2007-02-08 |
ATE328638T1 (de) | 2006-06-15 |
CA2480477A1 (en) | 2003-10-16 |
EP1700615B1 (en) | 2009-12-16 |
WO2003084597A1 (en) | 2003-10-16 |
DE60330605D1 (de) | 2010-01-28 |
US20030187395A1 (en) | 2003-10-02 |
ES2266803T3 (es) | 2007-03-01 |
JP4384917B2 (ja) | 2009-12-16 |
EP1490146B1 (en) | 2006-06-07 |
AU2003220592B2 (en) | 2008-11-20 |
US6780171B2 (en) | 2004-08-24 |
ATE451946T1 (de) | 2010-01-15 |
US20070021717A1 (en) | 2007-01-25 |
US20050027242A1 (en) | 2005-02-03 |
EP1700615A1 (en) | 2006-09-13 |
ES2338352T3 (es) | 2010-05-06 |
EP1490146A1 (en) | 2004-12-29 |
AU2003220592A1 (en) | 2003-10-20 |
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