JP2005519087A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2005519087A5 JP2005519087A5 JP2003571286A JP2003571286A JP2005519087A5 JP 2005519087 A5 JP2005519087 A5 JP 2005519087A5 JP 2003571286 A JP2003571286 A JP 2003571286A JP 2003571286 A JP2003571286 A JP 2003571286A JP 2005519087 A5 JP2005519087 A5 JP 2005519087A5
- Authority
- JP
- Japan
- Prior art keywords
- pyrimidin
- imidazo
- group
- phenyl
- ethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02290487A EP1340759A1 (en) | 2002-02-28 | 2002-02-28 | 1-[alkyl], 1-[(heteroaryl)alkyl] and 1-[(aryl)alkyl]-7-(pyrimidin-4-yl)-imidazo[1,2-a]pyrimidin-5(1H)-one derivatives |
| PCT/EP2003/002652 WO2003072580A1 (en) | 2002-02-28 | 2003-02-26 | 1-[ALKYL], 1-[HETEROARYL)ALKYL] AND 1-[ARYL)ALKYL]-7-(PYRIMIDIN-4-YL)-IMADAZO[1,2-a]PYRIMIDIN-5(1H)-ONE DERIVATIVES |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005519087A JP2005519087A (ja) | 2005-06-30 |
| JP2005519087A5 true JP2005519087A5 (https=) | 2006-04-13 |
| JP4484524B2 JP4484524B2 (ja) | 2010-06-16 |
Family
ID=27675771
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003571286A Expired - Fee Related JP4484524B2 (ja) | 2002-02-28 | 2003-02-26 | １−［アルキル］、１−［（ヘテロアリール）アルキル］および１−［（アリール）アルキル］−７−（ピリミジン−４−イル）−イミダゾ［１，２−ａ］ピリミジン−５（１Ｈ）−オン誘導体 |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US7429663B2 (https=) |
| EP (2) | EP1340759A1 (https=) |
| JP (1) | JP4484524B2 (https=) |
| KR (1) | KR100935262B1 (https=) |
| CN (1) | CN100441581C (https=) |
| AR (1) | AR038620A1 (https=) |
| AT (1) | ATE309246T1 (https=) |
| AU (1) | AU2003214127C1 (https=) |
| BR (1) | BR0308106A (https=) |
| CA (1) | CA2474875C (https=) |
| DE (1) | DE60302220T2 (https=) |
| DK (1) | DK1480981T3 (https=) |
| EA (1) | EA007459B1 (https=) |
| ES (1) | ES2250876T3 (https=) |
| IL (1) | IL163288A (https=) |
| MX (1) | MXPA04008365A (https=) |
| NO (1) | NO329756B1 (https=) |
| NZ (1) | NZ534467A (https=) |
| PL (1) | PL372664A1 (https=) |
| SI (1) | SI1480981T1 (https=) |
| TW (1) | TWI305534B (https=) |
| WO (1) | WO2003072580A1 (https=) |
| ZA (1) | ZA200406154B (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0415185A (pt) * | 2003-10-10 | 2006-11-28 | Pfizer Prod Inc | 2h-[1,2,4]triazol[4,3-a]pirazinas substituìdas como inibidores da gsk-3 |
| EP2258358A3 (en) | 2005-08-26 | 2011-09-07 | Braincells, Inc. | Neurogenesis with acetylcholinesterase inhibitor |
| EP2275095A3 (en) | 2005-08-26 | 2011-08-17 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation |
| EP1940389A2 (en) | 2005-10-21 | 2008-07-09 | Braincells, Inc. | Modulation of neurogenesis by pde inhibition |
| AU2006308889A1 (en) | 2005-10-31 | 2007-05-10 | Braincells, Inc. | GABA receptor mediated modulation of neurogenesis |
| US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
| EP2382975A3 (en) | 2006-05-09 | 2012-02-29 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
| US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
| WO2009155024A1 (en) * | 2008-05-30 | 2009-12-23 | Merck & Co., Inc. | Novel substituted indoles |
| EP2138494A1 (en) * | 2008-06-26 | 2009-12-30 | Sanofi-Aventis | Substituted alkyl pyrimidin-4-one derivatives |
| WO2010099217A1 (en) | 2009-02-25 | 2010-09-02 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
| HUE034503T2 (en) * | 2009-07-02 | 2018-02-28 | Sanofi Sa | 2,3-Dihydro-1-imidazo [1,2-a] pyrimidin-5-one derivatives, their preparation process and their use in medicine |
| HUE053939T2 (hu) | 2014-05-13 | 2021-08-30 | Hoffmann La Roche | Deuterált heterociklikus vegyületek és képalkotó kontrasztanyagként való használatuk |
| CN112574219A (zh) * | 2021-01-31 | 2021-03-30 | 湖北大学 | 一种苯并咪唑并嘧啶酮衍生物的合成方法 |
| CN115448921B (zh) * | 2021-06-08 | 2023-08-01 | 四川大学 | 一类咪唑烷并嘧啶酮化合物及在治疗HsClpP介导的疾病中的用途 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0184384B1 (en) * | 1984-12-06 | 1989-08-02 | Pfizer Inc. | Substituted dihydroquinolone carboxylic acids, anti-bacterial compositions containing them |
| AU733877C (en) * | 1996-12-05 | 2003-05-08 | Amgen, Inc. | Substituted pyrimidine compounds and their use |
| AR023052A1 (es) * | 1998-09-25 | 2002-09-04 | Mitsuharu Yoshimura Milton | Derivados de pirimidona |
| EP1184384A1 (en) * | 2000-09-01 | 2002-03-06 | Sanofi-Synthelabo | 1-(Alkyl), 1-((heteroaryl)alkyl) and 1-((aryl)alkyl)-7-pyridin-4-ylimidazo(1,2a)pyrimidin-5(1H)-one derivatives |
| EP1295884A1 (en) * | 2001-09-21 | 2003-03-26 | Sanofi-Synthelabo | 2-pyrimidinyl-6,7,8,9-tetrahydropyrimido[1,2-a]Pyrimidin-4-one and 7-Pyrimidinyl-2,3-Dihydroimidazo[1,2-a]Pyrimidin-5(1H)one derivatives |
-
2002
- 2002-02-28 EP EP02290487A patent/EP1340759A1/en not_active Withdrawn
-
2003
- 2003-02-26 CN CNB038079380A patent/CN100441581C/zh not_active Expired - Fee Related
- 2003-02-26 MX MXPA04008365A patent/MXPA04008365A/es active IP Right Grant
- 2003-02-26 EP EP03709786A patent/EP1480981B1/en not_active Expired - Lifetime
- 2003-02-26 KR KR1020047013439A patent/KR100935262B1/ko not_active Expired - Fee Related
- 2003-02-26 CA CA2474875A patent/CA2474875C/en not_active Expired - Fee Related
- 2003-02-26 SI SI200330137T patent/SI1480981T1/sl unknown
- 2003-02-26 US US10/504,679 patent/US7429663B2/en not_active Expired - Fee Related
- 2003-02-26 AT AT03709786T patent/ATE309246T1/de active
- 2003-02-26 ES ES03709786T patent/ES2250876T3/es not_active Expired - Lifetime
- 2003-02-26 PL PL03372664A patent/PL372664A1/xx not_active IP Right Cessation
- 2003-02-26 DK DK03709786T patent/DK1480981T3/da active
- 2003-02-26 JP JP2003571286A patent/JP4484524B2/ja not_active Expired - Fee Related
- 2003-02-26 DE DE60302220T patent/DE60302220T2/de not_active Expired - Lifetime
- 2003-02-26 WO PCT/EP2003/002652 patent/WO2003072580A1/en not_active Ceased
- 2003-02-26 NZ NZ534467A patent/NZ534467A/en not_active IP Right Cessation
- 2003-02-26 AU AU2003214127A patent/AU2003214127C1/en not_active Ceased
- 2003-02-26 BR BR0308106-0A patent/BR0308106A/pt active Search and Examination
- 2003-02-26 EA EA200400937A patent/EA007459B1/ru not_active IP Right Cessation
- 2003-02-27 TW TW092104221A patent/TWI305534B/zh not_active IP Right Cessation
- 2003-02-28 AR ARP030100658A patent/AR038620A1/es unknown
-
2004
- 2004-07-29 IL IL163288A patent/IL163288A/en not_active IP Right Cessation
- 2004-08-02 ZA ZA200406154A patent/ZA200406154B/en unknown
- 2004-08-26 NO NO20043567A patent/NO329756B1/no not_active IP Right Cessation
-
2008
- 2008-08-20 US US12/194,899 patent/US20080318980A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2005519087A5 (https=) | ||
| KR100983462B1 (ko) | 디하이드로프테리디논, 이의 제조방법 및 약제로서의 이의 용도 | |
| Yadav et al. | An overview on synthetic and pharmaceutical prospective of pyrido [2, 3‐d] pyrimidines scaffold | |
| Chen et al. | Design of 2, 5-dimethyl-3-(6-dimethyl-4-methylpyridin-3-yl)-7-dipropylaminopyrazolo [1, 5-a] pyrimidine (NBI 30775/R121919) and structure− activity relationships of a series of potent and orally active corticotropin-releasing factor receptor antagonists | |
| Joshi et al. | Pyrimidine-fused derivatives: Synthetic strategies and medicinal attributes | |
| Hammouda et al. | Insights into the medicinal chemistry of heterocycles integrated with a pyrazolo [1, 5-a] pyrimidine scaffold | |
| RU2502737C2 (ru) | Производные имидазопиридина или имидазопиримидина в качестве ингибиторов фосфодиэстеразы 10а | |
| CA2474875A1 (en) | 1-[alkyl], 1-[(heteroaryl)alkyl] and 1-[(aryl)alkyl]-7-(pyrimidin-4-yl)-imidazo[1,2,-a]pyrimidin-5(1h)-one derivatives | |
| JP2002516327A5 (https=) | ||
| JP2005504810A5 (https=) | ||
| JP2007514707A5 (https=) | ||
| RU2005137825A (ru) | Конденсированные производные пиримидина, обладающие активностью в отношении crf | |
| CA2457952A1 (en) | Substituted 2-pyrimidinyl-6,7,8,9-tetrahydropyrimido[1,2-a]pyrimidin-4-one and 7-pyrimidinyl-2,3-dihydroimidazo[1,2-a]pyrimidin-5(1h) one derivatives for neurodegenerative disorders | |
| AU2017272281A1 (en) | Inhibitors Of The Fibroblast Growth Factor Receptor | |
| Dymock et al. | Inhibitors of JAK2 and JAK3: an update on the patent literature 2010–2012 | |
| WO2022093856A1 (en) | Heterocyclic spiro compounds and methods of use | |
| KR20180080317A (ko) | 척수성 근위축증의 치료용 조성물 | |
| RU2007126570A (ru) | Аминоимидазолоны, применяемые для ингибирования бета-секретазы | |
| CA2518299A1 (en) | 8-substituted-6,7,8,9-tetrahydropyrimido[1,2-a]pyrimidin-4-one derivatives | |
| JP2000038350A (ja) | 糖尿病治療薬 | |
| AU2016351919A1 (en) | Compounds for treating amyotrophic lateral sclerosis | |
| KR102492378B1 (ko) | 선택적 jak 저해제로서 화합물, 및 이의 염 및 치료학적 용도 | |
| CA2457965A1 (en) | Substituted 2-pyridinyl-6,7,8,9-tetrahydropyrimido[1,2-a]pyrimidin-4-one and 7-pyridinyl-2,3-dihydroimidazo[1,2-a]pyrimidin-5(1h)one derivatives | |
| Gavrin et al. | Synthesis of pyrazolo [1, 5-α] pyrimidinone regioisomers | |
| Gilligan et al. | Synthesis and Structure− Activity Relationships of 8-(Pyrid-3-yl) pyrazolo [1, 5-a]-1, 3, 5-triazines: Potent, Orally Bioavailable Corticotropin Releasing Factor Receptor-1 (CRF1) Antagonists |