JP2005519073A - 睡眠標的モジュレーターを使用する睡眠障害の治療 - Google Patents

睡眠標的モジュレーターを使用する睡眠障害の治療 Download PDF

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Publication number
JP2005519073A
JP2005519073A JP2003567333A JP2003567333A JP2005519073A JP 2005519073 A JP2005519073 A JP 2005519073A JP 2003567333 A JP2003567333 A JP 2003567333A JP 2003567333 A JP2003567333 A JP 2003567333A JP 2005519073 A JP2005519073 A JP 2005519073A
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compound
group
therapeutic compound
therapeutic
sleep
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Japanese (ja)
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JP2005519073A5 (https=
Inventor
デービッド ジー． ハンガウアー，
ハリー ジェファーソン レイトン，
デール エム． エドガー，
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ヒプニオン， インコーポレイテッド
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Publication of JP2005519073A publication Critical patent/JP2005519073A/ja
Publication of JP2005519073A5 publication Critical patent/JP2005519073A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/55—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being also a pharmacologically or therapeutically active agent, i.e. the entire conjugate being a codrug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2003567333A 2002-01-18 2003-01-21 睡眠標的モジュレーターを使用する睡眠障害の治療 Withdrawn JP2005519073A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US34991202P 2002-01-18 2002-01-18
US35732002P 2002-02-15 2002-02-15
PCT/US2003/001845 WO2003068148A2 (en) 2002-01-18 2003-01-21 Treatment of sleep disorders using sleep target modulators

Publications (2)

Publication Number Publication Date
JP2005519073A true JP2005519073A (ja) 2005-06-30
JP2005519073A5 JP2005519073A5 (https=) 2005-12-22

Family

ID=27737408

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003567333A Withdrawn JP2005519073A (ja) 2002-01-18 2003-01-21 睡眠標的モジュレーターを使用する睡眠障害の治療

Country Status (6)

Country Link
US (2) US20030232839A1 (https=)
EP (1) EP1471913A2 (https=)
JP (1) JP2005519073A (https=)
AU (1) AU2003210598A1 (https=)
CA (1) CA2473586A1 (https=)
WO (1) WO2003068148A2 (https=)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UY28538A1 (es) * 2003-09-26 2005-04-29 Vertex Pharma Derivados de fenil-piperazina como moduladores de receptores muscarínicos
WO2005107700A2 (en) * 2004-04-26 2005-11-17 Immuneregen Biosciences, Inc. Anti-aging effects of substance p
JP4613031B2 (ja) * 2004-05-06 2011-01-12 エスエス製薬株式会社 催眠剤組成物
DK1940467T3 (da) * 2005-09-09 2017-02-13 Paladin Labs Inc Lægemiddelsammensætning med langvarig frigivelse
CN101252932B (zh) * 2005-09-09 2012-10-03 安吉利尼莱博法姆有限责任公司 用于一天给药一次的曲唑酮组合物
CA2641821C (en) 2006-02-16 2017-10-10 Imthera Medical, Inc. An rfid-based apparatus, system, and method for therapeutic treatment of a patient
US20110077200A1 (en) * 2006-12-06 2011-03-31 Somaxon Pharmaceuticals, Inc. Combination therapy using low-dose doxepin for the improvement of sleep
CA2697826A1 (en) 2007-10-09 2009-04-16 Imthera Medical, Inc. System and method for neural stimulation
EP2349139B1 (en) 2008-10-09 2017-05-31 Imthera Medical, Inc. Stimulation of a hypoglossal nerve for controlling the position of a patient's tongue
ES2370147T5 (es) † 2009-10-23 2019-03-06 Gruppo Cimbali Spa Máquina de café con regulación de presión de distribución y procedimiento relacionado con la misma
KR20120101650A (ko) 2009-11-10 2012-09-14 임테라 메디칼, 인코포레이티드 환자 혀의 위치를 제어하기 위한 혀밑 신경 자극용 시스템
US9532952B2 (en) 2011-01-28 2017-01-03 Physician's Seal, LLC Controlled-release compositions of melatonin combined with sedative and/or analgesic ingredients
US8691275B2 (en) 2011-01-28 2014-04-08 Zx Pharma, Llc Controlled-release melatonin compositions and related methods
AU2012214553B2 (en) 2011-02-11 2015-07-09 Sociétés des Produits Nestlé S.A. Multiparticulate L-menthol formulations and related methods
US8808736B2 (en) 2011-02-11 2014-08-19 Zx Pharma, Llc Enteric coated multiparticulate controlled release peppermint oil composition and related methods
US8911780B2 (en) 2011-02-11 2014-12-16 Zx Pharma, Llc Multiparticulate L-menthol formulations and related methods
US20120315337A1 (en) * 2011-06-07 2012-12-13 Shah Syed Multiparticulate 5-htp compositions and related methods
WO2013074390A1 (en) * 2011-11-14 2013-05-23 Merck Sharp & Dohme Corp. Triazolopyridinone pde10 inhibitors
ES2706152T3 (es) 2013-04-23 2019-03-27 Zx Pharma Llc Composición entérica de múltiples partículas revestida con subrevestimiento proteico
US10420756B2 (en) 2015-03-26 2019-09-24 Sen-Jam Pharmaceutical Llc. Methods and compositions to inhibit symptoms associated with veisalgia
JP7345495B2 (ja) * 2018-04-06 2023-09-15 ビーエーエスエフ ソシエタス・ヨーロピア アミンを合成する方法
EP4615585A1 (en) * 2022-11-11 2025-09-17 Gilgamesh Pharmaceuticals, Inc. Methods of using trazodone to reverse the effects of 5-ht2a receptor agonists

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5116852A (en) * 1990-12-03 1992-05-26 Bristol-Myers Squibb Co. Treatment of sleep disorders

Also Published As

Publication number Publication date
AU2003210598A2 (en) 2003-09-04
CA2473586A1 (en) 2003-08-21
US20060009465A1 (en) 2006-01-12
US20030232839A1 (en) 2003-12-18
EP1471913A2 (en) 2004-11-03
AU2003210598A1 (en) 2003-09-04
WO2003068148A3 (en) 2004-04-01
WO2003068148A2 (en) 2003-08-21

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